AR020558A1 - Un derivado de acido pirazolcarboxilico, su utilizacion, un procedimiento para su preparacion, composiciones farmaceuticas que lo contieneny compuestos utiles como intermediarios para prepararlo - Google Patents

Un derivado de acido pirazolcarboxilico, su utilizacion, un procedimiento para su preparacion, composiciones farmaceuticas que lo contieneny compuestos utiles como intermediarios para prepararlo

Info

Publication number
AR020558A1
AR020558A1 ARP000100386A ARP000100386A AR020558A1 AR 020558 A1 AR020558 A1 AR 020558A1 AR P000100386 A ARP000100386 A AR P000100386A AR P000100386 A ARP000100386 A AR P000100386A AR 020558 A1 AR020558 A1 AR 020558A1
Authority
AR
Argentina
Prior art keywords
procedure
preparation
pharmaceutical compositions
compositions containing
acid derivative
Prior art date
Application number
ARP000100386A
Other languages
English (en)
Original Assignee
Dupuis Laurent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9901201A external-priority patent/FR2789078B3/fr
Application filed by Dupuis Laurent filed Critical Dupuis Laurent
Publication of AR020558A1 publication Critical patent/AR020558A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/78—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • C07C251/80—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un derivado de ácido pirazolcarboxílico, que es la N-piperidino-5-(4-bromofenil)-1-(2,4-diclorofenil)-4-etilpirazol-3-carboxamida, sus sales ysolvatos son potentes antagonistas de los receptores a los canabinoides CB1. Los mismos se preparan porreac cion de un derivado funcional del ácido5-(4-bromofenil)-1-(2,4-diclorofenil)-4-etilpirazol-3-carboxílico con la 1-aminopiperidina, luego la salificacion eventual. También se divulga suutilizacion, un procedimiento para su preparacion,composiciones f armacéuticas que lo contienen y compuestos utiles como intermediarios para prepararlo.
ARP000100386A 1999-02-01 2000-01-28 Un derivado de acido pirazolcarboxilico, su utilizacion, un procedimiento para su preparacion, composiciones farmaceuticas que lo contieneny compuestos utiles como intermediarios para prepararlo AR020558A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9901201A FR2789078B3 (fr) 1999-02-01 1999-02-01 Derives d'acide pyrazolecarboxylique, leur preparation, les compositions pharmaceutiques en contenant
FR9910166A FR2789079B3 (fr) 1999-02-01 1999-08-02 Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant

Publications (1)

Publication Number Publication Date
AR020558A1 true AR020558A1 (es) 2002-05-15

Family

ID=26234792

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000100386A AR020558A1 (es) 1999-02-01 2000-01-28 Un derivado de acido pirazolcarboxilico, su utilizacion, un procedimiento para su preparacion, composiciones farmaceuticas que lo contieneny compuestos utiles como intermediarios para prepararlo

Country Status (37)

Country Link
US (3) US6432984B1 (es)
EP (1) EP1150961B1 (es)
JP (1) JP3794925B2 (es)
KR (1) KR100425405B1 (es)
CN (1) CN1146544C (es)
AR (1) AR020558A1 (es)
AT (1) ATE252562T1 (es)
AU (1) AU754771B2 (es)
BG (1) BG65193B1 (es)
BR (1) BR0007895A (es)
CA (1) CA2358885C (es)
CO (1) CO5160257A1 (es)
CZ (1) CZ297667B6 (es)
DE (1) DE60006070T2 (es)
DK (1) DK1150961T3 (es)
EE (1) EE04343B1 (es)
ES (1) ES2208267T3 (es)
FR (1) FR2789079B3 (es)
HK (1) HK1039329A1 (es)
HR (1) HRP20010564B1 (es)
HU (1) HUP0201278A3 (es)
ID (1) ID29534A (es)
IL (2) IL144198A0 (es)
IS (1) IS2448B (es)
ME (2) MEP11408A (es)
NO (1) NO319824B1 (es)
NZ (1) NZ512886A (es)
PE (1) PE20001493A1 (es)
PL (1) PL198422B1 (es)
PT (1) PT1150961E (es)
RS (1) RS50209B (es)
RU (1) RU2216542C2 (es)
SK (1) SK284203B6 (es)
TR (1) TR200102054T2 (es)
TW (1) TW581764B (es)
UA (1) UA66900C2 (es)
WO (1) WO2000046209A1 (es)

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