AR005197A1 - Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen - Google Patents

Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen

Info

Publication number
AR005197A1
AR005197A1 ARP960105851A ARP960105851A AR005197A1 AR 005197 A1 AR005197 A1 AR 005197A1 AR P960105851 A ARP960105851 A AR P960105851A AR P960105851 A ARP960105851 A AR P960105851A AR 005197 A1 AR005197 A1 AR 005197A1
Authority
AR
Argentina
Prior art keywords
preparation
pharmaceutical compositions
taxoids
derivatives
contain
Prior art date
Application number
ARP960105851A
Other languages
English (en)
Spanish (es)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AR005197A1 publication Critical patent/AR005197A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ARP960105851A 1995-12-22 1996-12-20 Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen AR005197A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
AR005197A1 true AR005197A1 (es) 1999-04-14

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105851A AR005197A1 (es) 1995-12-22 1996-12-20 Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen

Country Status (40)

Country Link
US (1) US5728849A (en, 2012)
EP (1) EP0876362B1 (en, 2012)
JP (1) JP3953106B2 (en, 2012)
KR (1) KR100500351B1 (en, 2012)
CN (1) CN1103766C (en, 2012)
AR (1) AR005197A1 (en, 2012)
AT (1) ATE250593T1 (en, 2012)
AU (1) AU712597B2 (en, 2012)
BG (1) BG63204B1 (en, 2012)
BR (1) BR9612135A (en, 2012)
CA (1) CA2238884C (en, 2012)
CO (1) CO4520184A1 (en, 2012)
CZ (1) CZ294972B6 (en, 2012)
DE (1) DE69630145T2 (en, 2012)
DK (1) DK0876362T3 (en, 2012)
DZ (1) DZ2149A1 (en, 2012)
EA (1) EA001533B1 (en, 2012)
ES (1) ES2202490T3 (en, 2012)
FR (1) FR2742751B1 (en, 2012)
HU (1) HU225032B1 (en, 2012)
IL (1) IL124994A (en, 2012)
IN (4) IN186768B (en, 2012)
MA (1) MA26412A1 (en, 2012)
MX (1) MX9804688A (en, 2012)
MY (1) MY113934A (en, 2012)
NO (1) NO317358B1 (en, 2012)
NZ (1) NZ324337A (en, 2012)
OA (1) OA10700A (en, 2012)
PE (1) PE25198A1 (en, 2012)
PL (1) PL189311B1 (en, 2012)
PT (1) PT876362E (en, 2012)
RO (1) RO116194B1 (en, 2012)
SK (1) SK282835B6 (en, 2012)
TN (1) TNSN96169A1 (en, 2012)
TR (1) TR199801179T2 (en, 2012)
TW (1) TW371659B (en, 2012)
UA (1) UA48205C2 (en, 2012)
UY (1) UY24386A1 (en, 2012)
WO (1) WO1997023473A1 (en, 2012)
ZA (1) ZA9610737B (en, 2012)

Families Citing this family (41)

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GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
AU782028B2 (en) 2000-02-02 2005-06-30 Florida State University Research Foundation, Inc. C10 carbonate substituted taxanes as antitumor agents
PT2298769E (pt) * 2001-02-24 2013-11-29 Boehringer Ingelheim Pharma Derivados de xantina, sua preparação e sua utilização como produto farmacêutico
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
CA2526278A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
BRPI0711558A2 (pt) 2006-05-04 2011-11-08 Boeringer Ingelheim Internat Gmbh polimorfos
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
EP3542801A1 (en) * 2007-08-17 2019-09-25 Boehringer Ingelheim International GmbH Purin derivatives for use in the treatment of fap-related diseases
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
AU2009281122C1 (en) * 2008-08-15 2016-04-21 Boehringer Ingelheim International Gmbh Purin derivatives for use in the treatment of fab-related diseases
WO2010029089A2 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
AU2009331471B2 (en) 2008-12-23 2015-09-03 Boehringer Ingelheim International Gmbh Salt forms of organic compound
TW201036975A (en) 2009-01-07 2010-10-16 Boehringer Ingelheim Int Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
AU2010323068B2 (en) 2009-11-27 2015-09-03 Boehringer Ingelheim International Gmbh Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin
JP6034781B2 (ja) 2010-05-05 2016-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 併用療法
PH12012502524A1 (en) 2010-06-24 2014-02-10 Boehringer Ingelheim Int Diabetes therapy
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
HUE061596T2 (hu) 2011-07-15 2023-07-28 Boehringer Ingelheim Int Szubsztituált dimer kinazolin származék, annak elõállítása és alkalmazása az I. és II. típusú cukorbetegség kezelésére szolgáló gyógyszerkészítményekben
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
JP6218811B2 (ja) 2012-05-14 2017-10-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｓｉｒｓ及び／又は敗血症の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
CN105849086B (zh) 2012-11-24 2018-07-31 杭州多禧生物科技有限公司 亲水性链接体及其在药物分子和细胞结合分子共轭反应上的应用
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
US9526728B2 (en) 2014-02-28 2016-12-27 Boehringer Ingelheim International Gmbh Medical use of a DPP-4 inhibitor
CN114262344A (zh) 2014-02-28 2022-04-01 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
CN108449940B (zh) 2015-07-12 2021-06-08 杭州多禧生物科技有限公司 与细胞结合分子的共轭偶联的桥连接体
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
US10155000B2 (en) 2016-06-10 2018-12-18 Boehringer Ingelheim International Gmbh Medical use of pharmaceutical combination or composition
KR20220147720A (ko) 2016-11-14 2022-11-03 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
WO2022078524A2 (en) 2021-11-03 2022-04-21 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
US5352806A (en) * 1992-04-17 1994-10-04 Abbott Laboratories Taxol derivatives
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Also Published As

Publication number Publication date
NO317358B1 (no) 2004-10-18
UY24386A1 (es) 2001-08-27
HK1017895A1 (en) 1999-12-03
DE69630145D1 (de) 2003-10-30
KR19990076680A (ko) 1999-10-15
CA2238884A1 (fr) 1997-07-03
IN188680B (en, 2012) 2002-10-26
MX9804688A (es) 1998-10-31
UA48205C2 (uk) 2002-08-15
CZ294972B6 (cs) 2005-04-13
TNSN96169A1 (fr) 2005-03-15
TR199801179T2 (xx) 1998-10-21
EA199800588A1 (ru) 1998-12-24
FR2742751A1 (fr) 1997-06-27
MA26412A1 (fr) 2004-12-20
CN1205697A (zh) 1999-01-20
FR2742751B1 (fr) 1998-01-30
DK0876362T3 (da) 2004-02-02
AU712597B2 (en) 1999-11-11
IL124994A (en) 2000-12-06
PT876362E (pt) 2004-02-27
BG102569A (en) 1999-04-30
PL189311B1 (pl) 2005-07-29
HU225032B1 (en) 2006-05-29
BR9612135A (pt) 1999-07-13
KR100500351B1 (ko) 2005-12-21
RO116194B1 (ro) 2000-11-30
ES2202490T3 (es) 2004-04-01
CO4520184A1 (es) 1997-10-15
JP3953106B2 (ja) 2007-08-08
BG63204B1 (bg) 2001-06-29
CZ196198A3 (cs) 1998-09-16
EA001533B1 (ru) 2001-04-23
TW371659B (en) 1999-10-11
DE69630145T2 (de) 2004-07-15
NO982580D0 (no) 1998-06-05
AU1180997A (en) 1997-07-17
ATE250593T1 (de) 2003-10-15
ZA9610737B (en) 1997-06-27
WO1997023473A1 (fr) 1997-07-03
NZ324337A (en) 2000-03-27
OA10700A (fr) 2002-11-27
PL327405A1 (en) 1998-12-07
IN186768B (en, 2012) 2001-11-03
EP0876362A1 (fr) 1998-11-11
IN188470B (en, 2012) 2002-09-28
SK282835B6 (sk) 2002-12-03
EP0876362B1 (fr) 2003-09-24
DZ2149A1 (fr) 2002-10-23
CN1103766C (zh) 2003-03-26
HUP9904046A1 (hu) 2001-04-28
IN188469B (en, 2012) 2002-09-28
NO982580L (no) 1998-06-05
IL124994A0 (en) 1999-01-26
JP2000502671A (ja) 2000-03-07
SK85398A3 (en) 1998-11-04
MY113934A (en) 2002-06-29
PE25198A1 (es) 1998-05-10
US5728849A (en) 1998-03-17
CA2238884C (fr) 2007-02-06
HUP9904046A3 (en) 2001-08-28

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