AP952A - Novel erthromycin derivatives, method for preparing same, and use thereof as drugs. - Google Patents

Novel erthromycin derivatives, method for preparing same, and use thereof as drugs. Download PDF

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Publication number
AP952A
AP952A APAP/P/1998/001318A AP9801318A AP952A AP 952 A AP952 A AP 952A AP 9801318 A AP9801318 A AP 9801318A AP 952 A AP952 A AP 952A
Authority
AP
ARIPO
Prior art keywords
formula
radical
compounds
methyl
dideoxy
Prior art date
Application number
APAP/P/1998/001318A
Other languages
English (en)
Other versions
AP9801318A0 (en
Inventor
Constantin Agouridas
Jean-Francis Chantot (Deceased)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AP9801318A0 publication Critical patent/AP9801318A0/xx
Application granted granted Critical
Publication of AP952A publication Critical patent/AP952A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
APAP/P/1998/001318A 1996-02-28 1997-02-27 Novel erthromycin derivatives, method for preparing same, and use thereof as drugs. AP952A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602472A FR2745290B1 (fr) 1996-02-28 1996-02-28 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PCT/FR1997/000351 WO1997031929A1 (fr) 1996-02-28 1997-02-27 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
AP9801318A0 AP9801318A0 (en) 1998-09-30
AP952A true AP952A (en) 2001-03-29

Family

ID=9489659

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1998/001318A AP952A (en) 1996-02-28 1997-02-27 Novel erthromycin derivatives, method for preparing same, and use thereof as drugs.

Country Status (31)

Country Link
US (1) US6096714A (zh)
EP (1) EP0885234B1 (zh)
JP (1) JP4102440B2 (zh)
KR (1) KR100486053B1 (zh)
CN (1) CN1168734C (zh)
AP (1) AP952A (zh)
AR (1) AR005999A1 (zh)
AT (1) ATE217633T1 (zh)
AU (1) AU716204B2 (zh)
BG (1) BG63207B1 (zh)
BR (1) BR9707709B1 (zh)
CZ (1) CZ293893B6 (zh)
DE (1) DE69712610T2 (zh)
DK (1) DK0885234T3 (zh)
EA (1) EA001376B1 (zh)
EE (1) EE9800265A (zh)
ES (1) ES2176698T3 (zh)
FR (1) FR2745290B1 (zh)
HU (1) HU227567B1 (zh)
IL (1) IL125622A (zh)
NO (1) NO983955L (zh)
NZ (1) NZ331600A (zh)
OA (1) OA10845A (zh)
PL (1) PL191736B1 (zh)
PT (1) PT885234E (zh)
SK (1) SK118498A3 (zh)
TR (1) TR199801713T2 (zh)
UA (1) UA58504C2 (zh)
WO (1) WO1997031929A1 (zh)
YU (1) YU37098A (zh)
ZA (1) ZA971659B (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003527301A (ja) * 1997-10-29 2003-09-16 大正製薬株式会社 エリスロマイシンａ誘導体
WO1999021870A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
FR2792637B1 (fr) * 1999-04-26 2001-06-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2780977B1 (fr) * 1998-07-09 2000-09-01 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
JP3947360B2 (ja) 1999-01-27 2007-07-18 ファイザー・プロダクツ・インク ケトリド抗生物質
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
WO2001010878A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO2001010880A1 (fr) * 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
AU6316400A (en) * 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
US20050014706A1 (en) * 2003-07-14 2005-01-20 Kanakeshwari Falzari Method of treating tuberculosis
WO2007069264A2 (en) * 2005-12-15 2007-06-21 Alembic Limited Reference standards for determining the purity of telithromycin and processes therefor
EP2214484A4 (en) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
CN105616437A (zh) * 2008-10-24 2016-06-01 森普拉制药公司 使用含三唑的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
CA2793884C (en) 2010-03-22 2019-09-10 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
DK2571506T3 (en) 2010-05-20 2017-08-28 Cempra Pharmaceuticals Inc PROCEDURES FOR THE MANUFACTURE OF MACROLIDES AND KETOLIDES AND INTERMEDIATES
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
AU2013239696C1 (en) 2012-03-27 2018-11-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0487411A1 (fr) * 1990-11-21 1992-05-27 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation, les nouveaux intermédiaires obtenus et leur application comme médicaments
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487411A (en) * 1892-12-06 Island
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0487411A1 (fr) * 1990-11-21 1992-05-27 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation, les nouveaux intermédiaires obtenus et leur application comme médicaments
US5444031A (en) * 1993-01-21 1995-08-22 Calgon Carbon Corporation Process for making catalytic carbon

Also Published As

Publication number Publication date
PL191736B1 (pl) 2006-06-30
NO983955D0 (no) 1998-08-27
DE69712610T2 (de) 2002-11-28
CN1212700A (zh) 1999-03-31
DK0885234T3 (da) 2002-08-26
WO1997031929A1 (fr) 1997-09-04
BG102691A (en) 1999-06-30
US6096714A (en) 2000-08-01
HU227567B1 (en) 2011-08-29
EE9800265A (et) 1999-02-15
NZ331600A (en) 1999-08-30
ES2176698T3 (es) 2002-12-01
PL328608A1 (en) 1999-02-01
AP9801318A0 (en) 1998-09-30
SK118498A3 (en) 1999-07-12
YU37098A (sh) 1999-07-28
JP4102440B2 (ja) 2008-06-18
EP0885234A1 (fr) 1998-12-23
BG63207B1 (bg) 2001-06-29
HUP9902576A3 (en) 2001-03-28
OA10845A (fr) 2003-02-05
JP2000505469A (ja) 2000-05-09
EA001376B1 (ru) 2001-02-26
ATE217633T1 (de) 2002-06-15
PT885234E (pt) 2002-10-31
UA58504C2 (uk) 2003-08-15
KR100486053B1 (ko) 2005-06-16
BR9707709B1 (pt) 2014-10-14
CN1168734C (zh) 2004-09-29
AU1929897A (en) 1997-09-16
HUP9902576A1 (hu) 1999-12-28
BR9707709A (pt) 1999-04-06
EA199800768A1 (ru) 1999-02-25
AR005999A1 (es) 1999-07-21
EP0885234B1 (fr) 2002-05-15
FR2745290B1 (fr) 1998-04-03
CZ293893B6 (cs) 2004-08-18
NO983955L (no) 1998-08-27
CZ258798A3 (cs) 1998-12-16
DE69712610D1 (de) 2002-06-20
IL125622A (en) 2003-10-31
FR2745290A1 (fr) 1997-08-29
KR19990087324A (ko) 1999-12-27
AU716204B2 (en) 2000-02-24
ZA971659B (en) 1998-02-26
IL125622A0 (en) 1999-04-11
TR199801713T2 (xx) 1998-12-21

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