AP424A - Piperidine derivatives, their preparation and their application in therapy. - Google Patents

Piperidine derivatives, their preparation and their application in therapy. Download PDF

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Publication number
AP424A
AP424A APAP/P/1993/000575A AP9300575A AP424A AP 424 A AP424 A AP 424A AP 9300575 A AP9300575 A AP 9300575A AP 424 A AP424 A AP 424A
Authority
AP
ARIPO
Prior art keywords
group
compound
compounds
alkyl
hydrogen atom
Prior art date
Application number
APAP/P/1993/000575A
Other languages
English (en)
Other versions
AP9300575A0 (en
Inventor
Samir Jegham
Itzchak Angel
Johannes Schoemaker
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of AP9300575A0 publication Critical patent/AP9300575A0/xx
Application granted granted Critical
Publication of AP424A publication Critical patent/AP424A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
APAP/P/1993/000575A 1992-09-28 1993-09-27 Piperidine derivatives, their preparation and their application in therapy. AP424A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211551A FR2696177B1 (fr) 1992-09-28 1992-09-28 Dérivés de pipéridine, leur préparation et leur application en thérapeutique.

Publications (2)

Publication Number Publication Date
AP9300575A0 AP9300575A0 (en) 1993-10-31
AP424A true AP424A (en) 1995-11-04

Family

ID=9433967

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1993/000575A AP424A (en) 1992-09-28 1993-09-27 Piperidine derivatives, their preparation and their application in therapy.

Country Status (24)

Country Link
US (1) US5434169A (ja)
EP (1) EP0591027A1 (ja)
JP (1) JPH06211838A (ja)
KR (1) KR940007020A (ja)
CN (1) CN1087339A (ja)
AP (1) AP424A (ja)
AU (1) AU658533B2 (ja)
CA (1) CA2107061A1 (ja)
CZ (1) CZ282080B6 (ja)
DZ (1) DZ1718A1 (ja)
FI (1) FI934221A (ja)
FR (1) FR2696177B1 (ja)
HU (2) HUT65303A (ja)
IL (1) IL107133A (ja)
MA (1) MA22981A1 (ja)
MX (1) MX9305932A (ja)
NO (1) NO933435L (ja)
NZ (1) NZ248776A (ja)
OA (1) OA09840A (ja)
PL (1) PL172860B1 (ja)
SK (1) SK103193A3 (ja)
TN (1) TNSN93107A1 (ja)
TW (1) TW272190B (ja)
ZA (1) ZA937156B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990045728A (ko) * 1995-09-18 1999-06-25 그레이엄 브레레톤, 레슬리 에드워즈 운동이상증에 대한 ５-ｈｔ３ 수용체 길항제
EP0918518A4 (en) * 1996-04-19 2002-05-02 Univ California TREATMENT OF MIND AND MOOD DISEASES WITH GLUTAMATERGIC MODULATORS.
FR2765221B1 (fr) * 1997-06-25 1999-07-30 Synthelabo Derives de 4-[(1h-imidazol-4-yl)piperidin-1-yl]anilide, leur preparation et leur application en therapeutique
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
GB9918425D0 (en) * 1999-08-04 1999-10-06 Novartis Ag Organic compounds
US6887870B1 (en) * 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
US7880017B2 (en) 2003-11-11 2011-02-01 Allergan, Inc. Process for the synthesis of imidazoles
US7183305B2 (en) 2003-11-11 2007-02-27 Allergan, Inc. Process for the synthesis of imidazoles
RU2422442C2 (ru) * 2005-07-29 2011-06-27 Ф. Хоффманн-Ля Рош Аг Производные индол-3-ил-карбонил-пиперидина и пиперазина
FR2925902B1 (fr) * 2008-01-02 2011-01-07 Sanofi Aventis DERIVES D'IMIDAZO°1,2-a!PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8609696B2 (en) 2008-12-18 2013-12-17 Boehringer Ingelheim International Gmbh Serotonin 5-HT2B receptor inhibitors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197840A1 (fr) * 1985-03-26 1986-10-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) (Imidazolyl-4) piperidines, leur préparation et leur application en thérapeutique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61210080A (ja) * 1985-03-13 1986-09-18 Chisso Corp アルデヒドラクトンの製造法
US5008390A (en) * 1985-05-23 1991-04-16 Smithkline Beckman Corporation Compounds for preparing 6-phenyl-2,3-dihydroimidazo[2,1-b]-thiazoles and corresponding thiazines
IT1230703B (it) * 1989-01-26 1991-10-29 Luso Farmaco Inst Derivati imidazolonici ad attivita' antiipertensiva, loro metodi di preparazione e composizioni farmaceutiche che li contengono.
US4925851A (en) * 1989-05-23 1990-05-15 Sandoz Pharmaceuticals Corp. 2- or 4-substituted-[2-(1H-imidazol-1-yl)ethyl]piperidines
FR2671083B1 (fr) * 1990-12-31 1994-12-23 Inst Nat Sante Rech Med Nouvelles 4-(4-imidazolyl) piperidines substituees en 1, leur preparation ainsi que leurs applications therapeutiques.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197840A1 (fr) * 1985-03-26 1986-10-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) (Imidazolyl-4) piperidines, leur préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
PL172860B1 (pl) 1997-12-31
JPH06211838A (ja) 1994-08-02
FR2696177A1 (fr) 1994-04-01
AP9300575A0 (en) 1993-10-31
NO933435D0 (no) 1993-09-27
MA22981A1 (fr) 1994-04-01
NO933435L (no) 1994-03-29
NZ248776A (en) 1995-09-26
HUT65303A (en) 1994-05-02
TW272190B (ja) 1996-03-11
HU211249A9 (en) 1995-11-28
US5434169A (en) 1995-07-18
FI934221A (fi) 1994-03-29
AU4860693A (en) 1994-04-14
FR2696177B1 (fr) 1995-05-12
DZ1718A1 (fr) 2002-02-17
CZ9302015A3 (en) 1994-04-13
MX9305932A (es) 1994-04-29
AU658533B2 (en) 1995-04-13
PL300515A1 (en) 1994-04-05
CN1087339A (zh) 1994-06-01
IL107133A (en) 1998-03-10
SK103193A3 (en) 1994-08-10
KR940007020A (ko) 1994-04-26
TNSN93107A1 (fr) 1994-03-17
ZA937156B (en) 1994-05-23
FI934221A0 (fi) 1993-09-27
CZ282080B6 (cs) 1997-05-14
CA2107061A1 (en) 1994-03-29
IL107133A0 (en) 1993-12-28
HU9302727D0 (en) 1993-12-28
EP0591027A1 (fr) 1994-04-06
OA09840A (fr) 1994-08-15

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