AP303A - Benzanilide derivatives as 5-HT 1D antaginists. - Google Patents
Benzanilide derivatives as 5-HT 1D antaginists. Download PDFInfo
- Publication number
- AP303A AP303A APAP/P/1992/000427A AP9200427A AP303A AP 303 A AP303 A AP 303A AP 9200427 A AP9200427 A AP 9200427A AP 303 A AP303 A AP 303A
- Authority
- AP
- ARIPO
- Prior art keywords
- methyl
- group
- compound
- phenyl
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C07D271/107—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with two aryl or substituted aryl radicals attached in positions 2 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919119931A GB9119931D0 (en) | 1991-09-18 | 1991-09-18 | Chemical compounds |
GB929205338A GB9205338D0 (en) | 1992-03-12 | 1992-03-12 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
AP9200427A0 AP9200427A0 (en) | 1992-10-31 |
AP303A true AP303A (en) | 1994-01-28 |
Family
ID=26299553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
APAP/P/1992/000427A AP303A (en) | 1991-09-18 | 1992-09-17 | Benzanilide derivatives as 5-HT 1D antaginists. |
Country Status (26)
Country | Link |
---|---|
US (2) | US5340810A (fr) |
EP (1) | EP0533268B1 (fr) |
JP (1) | JP3295143B2 (fr) |
KR (1) | KR930006011A (fr) |
CN (1) | CN1071919A (fr) |
AP (1) | AP303A (fr) |
AT (1) | ATE204262T1 (fr) |
AU (1) | AU656021B2 (fr) |
CA (1) | CA2078505A1 (fr) |
CZ (1) | CZ285492A3 (fr) |
DE (1) | DE69232003T2 (fr) |
DK (1) | DK0533268T3 (fr) |
ES (1) | ES2162792T3 (fr) |
FI (1) | FI924160A (fr) |
HU (1) | HUT65608A (fr) |
IL (1) | IL103198A (fr) |
IS (1) | IS1618B (fr) |
MX (1) | MX9205280A (fr) |
MY (1) | MY130233A (fr) |
NO (1) | NO923618L (fr) |
NZ (1) | NZ244373A (fr) |
OA (1) | OA10049A (fr) |
PL (1) | PL295960A1 (fr) |
PT (1) | PT533268E (fr) |
RU (1) | RU2077535C1 (fr) |
TW (1) | TW224097B (fr) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
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TW240217B (fr) * | 1992-12-30 | 1995-02-11 | Glaxo Group Ltd | |
EP0712397B1 (fr) * | 1993-08-06 | 1999-04-21 | Smithkline Beecham Plc | Derives amides employes comme antagonistes du recepteur 5ht1d |
JPH09504004A (ja) * | 1993-08-20 | 1997-04-22 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 5ht1dレセプター拮抗薬用アミドおよび尿素誘導体 |
WO1995006644A1 (fr) * | 1993-09-03 | 1995-03-09 | Smithkline Beecham Plc | Derives d'amide en tant qu'antagonistes du recepteur de 5ht1d |
WO1995006637A1 (fr) * | 1993-09-03 | 1995-03-09 | Smithkline Beecham Plc | Nouveaux derives d'indole et d'indoline en tant qu'antagonistes du recepteur de 5ht1d |
WO1995011243A1 (fr) * | 1993-10-19 | 1995-04-27 | Smithkline Beecham Plc | Derives de benzanilide en tant qu'antagonistes du recepteur de 5ht-1d |
AU1108395A (en) * | 1993-12-07 | 1995-06-27 | Smithkline Beecham Plc | Heterocyclic biphenylylamides useful as 5ht1d antagonists |
US20020086053A1 (en) * | 1993-12-15 | 2002-07-04 | Smithkline Beecham Plc | Formulations, tablets of paroxetine and process to prepare them |
GB9326008D0 (en) * | 1993-12-21 | 1994-02-23 | Smithkline Beecham Plc | Novel compounds |
WO1995017398A1 (fr) * | 1993-12-21 | 1995-06-29 | Smithkline Beecham Plc | Derives indole, indoline et quinoleine possedant une activite antagoniste (anti-depressive) du 5ht¿1d? |
EP0758330A1 (fr) * | 1994-05-06 | 1997-02-19 | Smithkline Beecham Plc | Diphenylcarboxamides utiles en tant qu'antagonistes de 5-ht1d |
WO1995032967A1 (fr) * | 1994-05-28 | 1995-12-07 | Smithkline Beecham Plc | Derives amide a activite antagoniste par rapport a 5ht1d |
FR2722788B1 (fr) * | 1994-07-20 | 1996-10-04 | Pf Medicament | Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant |
US5597826A (en) | 1994-09-14 | 1997-01-28 | Pfizer Inc. | Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist |
US5527920A (en) * | 1994-11-18 | 1996-06-18 | Singh; Inder P. | Economical manufacturing process for 1,2,3-triazoles |
HUT77650A (hu) | 1994-12-22 | 1998-07-28 | Smithkline Beecham P.L.C. | Spiro{(furo[2,3-f]indol-, furo[2,3-g]kinolin- és furo[2,3-h]benzazepin)-3,4'-piperidin}-származékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények |
GB9507203D0 (en) * | 1995-04-07 | 1995-05-31 | Smithkline Beecham Plc | Novel compounds |
FR2740134B1 (fr) * | 1995-10-18 | 1998-01-09 | Pf Medicament | Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant |
US6166034A (en) * | 1995-11-08 | 2000-12-26 | Smithkline Beecham P. L. C | Spiro piperidine derivatives as 5HT1D receptor antagonists |
US5670526A (en) * | 1995-12-21 | 1997-09-23 | Otsuka Pharmaceutical Co., Ltd. | 1,3,4-oxadiazoles |
FR2744450A1 (fr) * | 1996-02-02 | 1997-08-08 | Pf Medicament | Nouvelles naphtylpiperazines derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
FR2744449B1 (fr) * | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperazines aromatiques derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
GB9605883D0 (en) * | 1996-03-20 | 1996-05-22 | Smithkline Beecham Plc | Novel compounds |
GB9605945D0 (en) * | 1996-03-21 | 1996-05-22 | Smithkline Beecham Plc | Novel compounds |
SE9601110D0 (sv) * | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
JP3118467B2 (ja) | 1996-03-29 | 2000-12-18 | ファイザー インク. | 5―ht1aおよび/または5―ht1d受容体の選択的(アンタ)アゴニストとしてのベンジル(イデン)―ラクタム誘導体、その調製法及びその使用法 |
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FR2761064B1 (fr) * | 1997-03-20 | 1999-06-04 | Pf Medicament | Piperazines derivees d'amines cycliques, leur preparation et leur application comme medicaments |
IL132409A0 (en) * | 1997-04-18 | 2001-03-19 | Smithkline Beecham Plc | Indole derivatives having combined 5ht1a 5ht1b and 5ht1d receptor antagonist activity |
SE9900190D0 (sv) | 1999-01-22 | 1999-01-22 | Astra Ab | New compounds |
SE9702799D0 (sv) | 1997-07-25 | 1997-07-25 | Astra Ab | New compounds |
JP2001512727A (ja) * | 1997-08-09 | 2001-08-28 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 5ht−1受容体のリガンドとしてのニ環式化合物 |
SE9703375D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | A new combination |
SE9703376D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | A new combination |
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GB9826412D0 (en) * | 1998-12-03 | 1999-01-27 | Glaxo Group Ltd | Chemical compounds |
HUP0202787A3 (en) | 1999-09-25 | 2003-12-29 | Smithkline Beecham Plc | Piperazine derivatives as 5-ht1b antagonists, process for their preparation and pharmaceutical compositions containing them |
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USRE46117E1 (en) | 1999-12-22 | 2016-08-23 | Teva Pharmaceuticals International Gmbh | Modulators of dopamine neurotransmission |
SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
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EP1429765A2 (fr) | 2001-09-14 | 2004-06-23 | Methylgene, Inc. | Inhibiteurs de l'histone-deacetylase |
GB0124933D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
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GB0124939D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124941D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124934D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124936D0 (en) * | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124931D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
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GB0308186D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
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WO2007077457A2 (fr) * | 2006-01-06 | 2007-07-12 | The Royal Veterinary College | Traitement de la fourbure chez le cheval |
EP1921072A1 (fr) * | 2006-11-10 | 2008-05-14 | Laboratorios del Dr. Esteve S.A. | Dérivés de 1,2,3-triazole comme modulateurs du récepteur cannabinoide |
ES2583067T3 (es) | 2010-07-23 | 2016-09-16 | The Board Of Trustees Of The Universityof Illinois | Aparato y métodos para la síntesis automática de moléculas pequeñas |
WO2012079232A1 (fr) * | 2010-12-15 | 2012-06-21 | Lai Hung-Cheng | Composés utilisés pour traiter le cancer et utilisation associée compounds used for treating cancer and the use thereof |
US9302996B2 (en) | 2010-12-17 | 2016-04-05 | Mitsubishi Tanabe Pharma Corporation | Continuous arycyclic compound |
EP2787997A4 (fr) | 2011-12-08 | 2015-05-27 | Ivax Int Gmbh | Bromhydrate de pridopidine |
MX2014011971A (es) | 2012-04-04 | 2015-01-16 | Ivax Int Gmbh | Composiciones farmaceuticas para terapia de combinacion. |
ES2690315T3 (es) | 2012-06-15 | 2018-11-20 | Mitsubishi Tanabe Pharma Corporation | Compuestos de imidazol y triazol como inhibidores de DGAT-1 |
WO2020183011A1 (fr) | 2019-03-14 | 2020-09-17 | Institut Curie | Inhibiteurs de htr1d et leurs utilisations dans le traitement du cancer |
WO2023205475A1 (fr) * | 2022-04-21 | 2023-10-26 | Nimbus Clotho, Inc. | Inhibiteurs de ctps1 et leurs utilisations |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2545978A1 (de) * | 1974-10-14 | 1976-04-22 | Chugai Pharmaceutical Co Ltd | Bis-benzamidobenzol-derivate |
EP0058779A2 (fr) * | 1981-01-10 | 1982-09-01 | Dr. Karl Thomae GmbH | Carboxamides, leur préparation et leur utilisation comme médicaments |
EP0335381A1 (fr) * | 1988-03-30 | 1989-10-04 | Boehringer Ingelheim Kg | Imidazoles substitués en 2,3,4 et 1,2,4-triazoles substitués en 3,4,5, leur préparation et leur utilisation |
Family Cites Families (15)
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US3192213A (en) * | 1962-10-12 | 1965-06-29 | Olin Mathieson | Aminoalkyl anilides |
DE1668723A1 (de) * | 1966-09-16 | 1971-04-08 | Toyo Jozo Kk | Verfahren zum Herstellen von Verbindungen mit Saeureamid-Bindung |
US4058523A (en) * | 1974-10-14 | 1977-11-15 | Chugai Seiyaku Kabushiki Kaisha | Bis(benzamido)-benzene derivatives |
US4013647A (en) * | 1976-03-23 | 1977-03-22 | American Home Products Corporation | Morpholine containing tetrazole-5-carboxamide derivatives |
DE3005287A1 (de) * | 1980-02-13 | 1981-08-20 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
US4735959A (en) * | 1981-01-10 | 1988-04-05 | Dr. Karl Thomae Gmbh | Carboxylic acid amides and pharmaceutical compositions containing them |
US4562201A (en) * | 1982-07-26 | 1985-12-31 | American Hospital Supply Corporation | Aminomethyl benzanilides |
US4579866A (en) * | 1984-05-29 | 1986-04-01 | Usv Pharmaceutical Corp. | Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents |
US4778796A (en) * | 1985-07-19 | 1988-10-18 | Dainippon Pharmaceutical Co., Ltd. | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same |
DE3600288A1 (de) * | 1986-01-08 | 1987-07-16 | Bayer Ag | Verwendung von amiden zur verbesserung der kulturpflanzen-vertraeglichkeit von herbizid wirksamen sulfonylharnstoff-derivaten |
CA1334092C (fr) * | 1986-07-11 | 1995-01-24 | David John Carini | Imidazoles bloquant les recepteurs de l'angiotensine ii |
US4853398A (en) * | 1987-04-13 | 1989-08-01 | Eli Lilly And Company | Leukotriene antagonists and use thereas |
US4826990A (en) * | 1987-09-30 | 1989-05-02 | American Home Products Corporation | 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents |
EP0324521A3 (fr) * | 1988-01-11 | 1991-11-27 | Duphar International Research B.V | Méthode de traitement des maladies hématologiques et compositions pharmaceutiques pour cet usage |
ATE81651T1 (de) * | 1988-10-10 | 1992-11-15 | Akzo Nv | Substituierte aromatische verbindungen mit zentraler nervensystem-wirkung. |
-
1992
- 1992-09-14 EP EP92202806A patent/EP0533268B1/fr not_active Expired - Lifetime
- 1992-09-14 AT AT92202806T patent/ATE204262T1/de not_active IP Right Cessation
- 1992-09-14 PT PT92202806T patent/PT533268E/pt unknown
- 1992-09-14 ES ES92202806T patent/ES2162792T3/es not_active Expired - Lifetime
- 1992-09-14 DE DE69232003T patent/DE69232003T2/de not_active Expired - Fee Related
- 1992-09-14 DK DK92202806T patent/DK0533268T3/da active
- 1992-09-17 TW TW081107321A patent/TW224097B/zh active
- 1992-09-17 OA OA60277A patent/OA10049A/en unknown
- 1992-09-17 RU SU925052871A patent/RU2077535C1/ru active
- 1992-09-17 PL PL29596092A patent/PL295960A1/xx unknown
- 1992-09-17 CZ CS922854A patent/CZ285492A3/cs unknown
- 1992-09-17 JP JP27361992A patent/JP3295143B2/ja not_active Expired - Fee Related
- 1992-09-17 NO NO92923618A patent/NO923618L/no unknown
- 1992-09-17 HU HU9202968A patent/HUT65608A/hu unknown
- 1992-09-17 KR KR1019920016904A patent/KR930006011A/ko not_active Application Discontinuation
- 1992-09-17 CA CA002078505A patent/CA2078505A1/fr not_active Abandoned
- 1992-09-17 AU AU24530/92A patent/AU656021B2/en not_active Ceased
- 1992-09-17 NZ NZ244373A patent/NZ244373A/en unknown
- 1992-09-17 FI FI924160A patent/FI924160A/fi not_active Application Discontinuation
- 1992-09-17 US US07/946,098 patent/US5340810A/en not_active Expired - Fee Related
- 1992-09-17 MY MYPI92001663A patent/MY130233A/en unknown
- 1992-09-17 MX MX9205280A patent/MX9205280A/es not_active IP Right Cessation
- 1992-09-17 AP APAP/P/1992/000427A patent/AP303A/en active
- 1992-09-17 IS IS3915A patent/IS1618B/is unknown
- 1992-09-17 IL IL10319892A patent/IL103198A/en not_active IP Right Cessation
- 1992-09-17 CN CN92111660A patent/CN1071919A/zh active Pending
-
1994
- 1994-05-03 US US08/237,297 patent/US5510350A/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2545978A1 (de) * | 1974-10-14 | 1976-04-22 | Chugai Pharmaceutical Co Ltd | Bis-benzamidobenzol-derivate |
EP0058779A2 (fr) * | 1981-01-10 | 1982-09-01 | Dr. Karl Thomae GmbH | Carboxamides, leur préparation et leur utilisation comme médicaments |
EP0335381A1 (fr) * | 1988-03-30 | 1989-10-04 | Boehringer Ingelheim Kg | Imidazoles substitués en 2,3,4 et 1,2,4-triazoles substitués en 3,4,5, leur préparation et leur utilisation |
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