AP231A - Antimalarial composition. - Google Patents

Antimalarial composition. Download PDF

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Publication number
AP231A
AP231A APAP/P/1991/000275A AP9100275A AP231A AP 231 A AP231 A AP 231A AP 9100275 A AP9100275 A AP 9100275A AP 231 A AP231 A AP 231A
Authority
AP
ARIPO
Prior art keywords
effective amount
pharmaceutical composition
benflumetol
artemether
compound
Prior art date
Application number
APAP/P/1991/000275A
Other languages
English (en)
Other versions
AP9100275A0 (en
Inventor
Yiqing Zhou
Dianxi Ning
Shufen Wang
Deben Ding
Guofu Li
Chengqoi Shan
Guangyu Liu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25742651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP231(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AP9100275A0 publication Critical patent/AP9100275A0/xx
Application granted granted Critical
Publication of AP231A publication Critical patent/AP231A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
APAP/P/1991/000275A 1990-08-08 1991-06-12 Antimalarial composition. AP231A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN90106722A CN1058717A (zh) 1990-08-08 1990-08-08 抗疟新药—复方蒿甲醚及其制备方法
CN91102575A CN1085527C (zh) 1990-08-08 1991-04-24 增效复方抗疟药本芴醇的制备方法

Publications (2)

Publication Number Publication Date
AP9100275A0 AP9100275A0 (en) 1991-07-31
AP231A true AP231A (en) 1993-01-31

Family

ID=25742651

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1991/000275A AP231A (en) 1990-08-08 1991-06-12 Antimalarial composition.

Country Status (27)

Country Link
US (1) US5677331A (pt)
EP (1) EP0500823B1 (pt)
JP (1) JP2562857B2 (pt)
KR (1) KR100221689B1 (pt)
CN (2) CN1058717A (pt)
AP (1) AP231A (pt)
AT (1) ATE135209T1 (pt)
AU (1) AU642747B2 (pt)
CA (1) CA2065285C (pt)
DE (2) DE10199038I2 (pt)
DK (1) DK0500823T3 (pt)
EG (1) EG19905A (pt)
ES (1) ES2084168T3 (pt)
FI (1) FI921491A (pt)
GR (1) GR3019313T3 (pt)
HK (1) HK1000312A1 (pt)
HU (1) HU227345B1 (pt)
IE (1) IE72095B1 (pt)
IL (1) IL98463A (pt)
LU (1) LU90844I2 (pt)
MA (1) MA22176A1 (pt)
NL (1) NL300048I2 (pt)
NZ (1) NZ238477A (pt)
PT (1) PT97945B (pt)
SA (1) SA91120263B1 (pt)
WO (1) WO1992002217A1 (pt)
ZA (1) ZA914490B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637594A (en) * 1991-04-11 1997-06-10 Ciba Geigy Corporation Antimalarial synergistic compositions containing benflumetol
JP3560970B2 (ja) * 1992-02-07 2004-09-02 ノバルティス アクチェンゲゼルシャフト ベンゾフルメトールを含有する抗マラリア性の相乗作用組成物
WO1995027964A1 (en) * 1994-04-12 1995-10-19 Qualcomm Incorporated Method and apparatus for freight transportation using a satellite navigation system
US5657088A (en) * 1995-12-22 1997-08-12 Cirrus Logic, Inc. System and method for extracting caption teletext information from a video signal
US6136847A (en) * 1996-12-02 2000-10-24 Johns Hopkins University Water-soluble trioxanes as potent and safe antimalarial agents
CH692321A5 (de) 1997-11-03 2002-05-15 Mepha Ag Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält.
CO5040050A1 (es) 1998-06-25 2001-05-29 Novartis Ag Compuestos de 2-amino-1-(9-arilmetilidina-2,7-dicloro-9h- fluoren-4-ilo)-etanoles n-sustituidos, procedimientos para su obtencion y preparados farmaceuticos que los contienen .
IN191696B (pt) 1999-02-12 2003-12-20 Council Scient Ind Res
AU2000255631A1 (en) * 2000-03-31 2001-10-15 Council Of Scientific And Industrial Research A synergistic anti-malarial formulation
AU2001295979A1 (en) * 2000-10-20 2002-04-29 Ajinomoto Co., Inc. Medicinal compositions, dose and method for treating malaria
US7842719B2 (en) * 2002-10-31 2010-11-30 Kemin Foods, L.C. Use of endoperoxides for the treatment of infections caused by flaviviridae, including hepatitis C, bovine viral diarrhea and classical swine fever virus
WO2004075817A2 (en) * 2003-02-26 2004-09-10 Vrije Universiteit Brussel Suspendable pharmaceutical composition
AP2006003557A0 (en) * 2003-09-04 2006-04-30 Cipla Ltd Antimalarial compositions and process thereof.
US20110206636A1 (en) * 2003-09-16 2011-08-25 Kemin Foods, LLC Use of Endoperoxides for the Treatment of Infections Caused by Flaviviridae, Including Hepatitis C, Bovine Viral Diarrhea and Classical Swine Fever Virus
WO2007017646A2 (en) * 2005-08-05 2007-02-15 Cipla Limited Anti-malarial composition comprising artesunate and lumefantrine
WO2007036947A1 (en) * 2005-09-30 2007-04-05 Ipca Laboratories Limited Delayed release anti-malarial composition
US20090324715A1 (en) * 2006-06-26 2009-12-31 Sumit Madan High dose oral pharmaceutical compositions of artemether and lumefantrine
CN100463669C (zh) * 2006-08-31 2009-02-25 广州市医药工业研究所 复方蒿甲醚自乳化剂
WO2008098586A1 (en) * 2007-02-13 2008-08-21 Dafra Pharma N.V. Pharmaceutical carrier composition and pharmaceutical composition
CH700941B1 (de) * 2007-12-04 2010-11-15 Mepha Ag Pharmazeutische Zusammensetzung zur Behandlung von Malaria.
FR2926993B1 (fr) * 2008-02-06 2011-03-11 Sanofi Aventis Association entre un sel de bis-thiazolium ou l'un de ses precurseurs et l'artemisinine ou l'un de ses derives pour le traitement du paludisme
WO2010004573A1 (en) * 2008-07-07 2010-01-14 Ipca Laboratories Limited Synergistic antimalarial pharmaceutical composition
US10561157B2 (en) * 2012-03-30 2020-02-18 Sudzucker Aktiengesellschaft Mannheim/Ochsenfurt Rolling compound powders for applying on the surface of chewing gum core materials
CN103251584A (zh) * 2013-05-09 2013-08-21 西安力邦制药有限公司 注射用蒿甲醚/本芴醇复方脂肪乳的制备及其在疟疾治疗中的应用
WO2015140709A1 (en) * 2014-03-19 2015-09-24 Novartis Ag Solid pharmaceutical dosage forms
US20180303837A1 (en) * 2017-04-24 2018-10-25 Novartis Ag Therapeutic regimen
CN113599382B (zh) * 2021-08-20 2023-01-03 兰州大学 喹啉类衍生物在制备治疗糖尿病及其并发症药物中的应用
CN116747218B (zh) * 2023-08-21 2023-10-31 山东省中医药研究院 百秋李醇、百秋李醇复合抗疟组合物及制备抗疟原虫药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0362810A1 (en) * 1988-10-07 1990-04-11 Hoechst Aktiengesellschaft Antimalarial compositions using quinidine, artemisinine and its derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85100978A (zh) * 1985-04-01 1986-08-13 中医研究院中药研究所 还原青蒿素的生产工艺
CN85100781B (zh) * 1985-04-01 1988-07-06 广西壮族自治区桂林制药厂 抗疟药物青蒿酯的制备方法
CN87101346A (zh) * 1987-06-09 1988-03-09 山东省中医药研究所 青蒿素提取工艺
CN1029680C (zh) * 1988-11-10 1995-09-06 军事医学科学院微生物流行病研究所 抗疟新药苯芴醇的合成新工艺

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0362810A1 (en) * 1988-10-07 1990-04-11 Hoechst Aktiengesellschaft Antimalarial compositions using quinidine, artemisinine and its derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Parasitology 90, 1985, pp. 705-715, espec. 709-710 *

Also Published As

Publication number Publication date
DK0500823T3 (da) 1996-04-01
HU9201528D0 (en) 1992-08-28
CA2065285A1 (en) 1992-02-09
ES2084168T3 (es) 1996-05-01
AP9100275A0 (en) 1991-07-31
JP2562857B2 (ja) 1996-12-11
HK1000312A1 (en) 1998-02-27
AU642747B2 (en) 1993-10-28
EP0500823B1 (en) 1996-03-13
KR100221689B1 (ko) 1999-09-15
LU90844I2 (fr) 2002-01-24
IE911989A1 (en) 1992-02-12
ATE135209T1 (de) 1996-03-15
CN1058717A (zh) 1992-02-19
SA91120263B1 (ar) 2004-08-31
ZA914490B (en) 1992-03-25
WO1992002217A1 (en) 1992-02-20
NL300048I2 (nl) 2002-03-01
GR3019313T3 (en) 1996-06-30
KR920702217A (ko) 1992-09-03
PT97945A (pt) 1992-04-30
HU227345B1 (en) 2011-04-28
PT97945B (pt) 1998-11-30
IL98463A0 (en) 1992-07-15
JPH05501568A (ja) 1993-03-25
HUT61664A (en) 1993-03-01
US5677331A (en) 1997-10-14
NZ238477A (en) 1992-12-23
AU7954991A (en) 1992-03-02
NL300048I1 (nl) 2001-10-01
EG19905A (en) 1996-05-31
MA22176A1 (fr) 1991-12-31
DE69117922D1 (de) 1996-04-18
CN1085527C (zh) 2002-05-29
DE69117922T2 (de) 1996-09-05
FI921491A0 (fi) 1992-04-03
CA2065285C (en) 2000-05-09
DE10199038I2 (de) 2007-01-04
IE72095B1 (en) 1997-03-12
EP0500823A1 (en) 1992-09-02
FI921491A (fi) 1992-04-03
CN1065993A (zh) 1992-11-11
DE10199038I1 (de) 2001-11-22
IL98463A (en) 1995-10-31

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