AP2014007844A0 - Substituted annulated pyrimidines and triazines, and use thereof - Google Patents
Substituted annulated pyrimidines and triazines, and use thereofInfo
- Publication number
- AP2014007844A0 AP2014007844A0 AP2014007844A AP2014007844A AP2014007844A0 AP 2014007844 A0 AP2014007844 A0 AP 2014007844A0 AP 2014007844 A AP2014007844 A AP 2014007844A AP 2014007844 A AP2014007844 A AP 2014007844A AP 2014007844 A0 AP2014007844 A0 AP 2014007844A0
- Authority
- AP
- ARIPO
- Prior art keywords
- triazines
- pyrimidines
- substituted annulated
- annulated
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102012200349A DE102012200349A1 (de) | 2012-01-11 | 2012-01-11 | Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung |
PCT/EP2013/050381 WO2013104703A1 (de) | 2012-01-11 | 2013-01-10 | Substituierte annellierte pyrimidine und triazine und ihre verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
AP2014007844A0 true AP2014007844A0 (en) | 2014-07-31 |
Family
ID=47559479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2014007844A AP2014007844A0 (en) | 2012-01-11 | 2013-01-10 | Substituted annulated pyrimidines and triazines, and use thereof |
Country Status (29)
Country | Link |
---|---|
US (2) | US20140357637A1 (ru) |
EP (1) | EP2802592A1 (ru) |
JP (1) | JP6251183B2 (ru) |
KR (1) | KR20140114416A (ru) |
CN (1) | CN104812762B (ru) |
AP (1) | AP2014007844A0 (ru) |
AU (1) | AU2013208968A1 (ru) |
BR (1) | BR112014016971A8 (ru) |
CA (1) | CA2860855A1 (ru) |
CL (1) | CL2014001779A1 (ru) |
CO (1) | CO7000776A2 (ru) |
CR (1) | CR20140327A (ru) |
CU (1) | CU20140082A7 (ru) |
DE (1) | DE102012200349A1 (ru) |
DO (1) | DOP2014000160A (ru) |
EA (1) | EA025837B1 (ru) |
EC (1) | ECSP14008556A (ru) |
GT (1) | GT201400147A (ru) |
HK (1) | HK1211585A1 (ru) |
IL (1) | IL233460A0 (ru) |
MA (1) | MA35844B1 (ru) |
MX (1) | MX2014008201A (ru) |
NZ (1) | NZ626394A (ru) |
PE (1) | PE20142293A1 (ru) |
PH (1) | PH12014501595A1 (ru) |
SG (2) | SG11201403345UA (ru) |
TN (1) | TN2014000298A1 (ru) |
WO (1) | WO2013104703A1 (ru) |
ZA (1) | ZA201405042B (ru) |
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EP2708539A1 (de) | 2010-07-09 | 2014-03-19 | Bayer Intellectual Property GmbH | Annellierte pyrimidine und triazine und ihre verwendung zur behandlung bzw. prophylaxe von herz-kreislauf-erkrankungen |
CN103619845B (zh) * | 2011-04-21 | 2016-08-17 | 拜耳知识产权有限责任公司 | 氟烷基取代的吡唑并吡啶及其用途 |
DE102012200349A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung |
DE102012200360A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte Triazine und ihre Verwendung |
DE102012200352A1 (de) * | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte, annellierte Imidazole und Pyrazole und ihre Verwendung |
CA2866213A1 (en) * | 2012-03-06 | 2013-09-12 | Bayer Intellectual Property Gmbh | Substituted azabicycles and use thereof |
TW201439090A (zh) | 2012-11-30 | 2014-10-16 | Astellas Pharma Inc | 咪唑並吡啶化合物 |
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US9783552B2 (en) | 2013-12-11 | 2017-10-10 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
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KR20180002657A (ko) | 2015-05-06 | 2018-01-08 | 바이엘 파마 악티엔게젤샤프트 | 전신 경화증 (SSc)에 수반되는 수족지 궤양 (DU)의 치료를 위한 sGC 자극제, sGC 활성화제 단독 및 PDE5 억제제와의 조합물의 용도 |
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MX2014000029A (es) | 2011-07-06 | 2014-02-17 | Bayer Ip Gmbh | Pirazolopiridinas sustituidas con heteroarilo y uso de las mismas como estimuladores de guanilato ciclasas solubles. |
MX359032B (es) | 2011-09-01 | 2018-09-12 | Hoffmann La Roche | Inhibidores de pirrolopirazina cinasa. |
WO2013030288A1 (de) | 2011-09-02 | 2013-03-07 | Bayer Intellectual Property Gmbh | Substituierte annellierte pyrimidine und ihre verwendung |
DE102012200349A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung |
DE102012200352A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte, annellierte Imidazole und Pyrazole und ihre Verwendung |
DE102012200360A1 (de) | 2012-01-11 | 2013-07-11 | Bayer Intellectual Property Gmbh | Substituierte Triazine und ihre Verwendung |
CA2866213A1 (en) | 2012-03-06 | 2013-09-12 | Bayer Intellectual Property Gmbh | Substituted azabicycles and use thereof |
BR112015020298A2 (pt) | 2013-03-01 | 2017-07-18 | Bayer Pharma AG | pirimidinas de anel fundido substituídas com trifluormetil e uso das mesmas |
JP2016513129A (ja) | 2013-03-01 | 2016-05-12 | バイエル・ファルマ・アクティエンゲゼルシャフト | ベンジル−置換ピラゾロピリジンおよびその使用 |
US9605008B2 (en) | 2013-07-10 | 2017-03-28 | Bayer Pharma Aktiengesellschaft | Benzyl-1H-pyrazolo[3,4-b]pyridines and use thereof |
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2012
- 2012-01-11 DE DE102012200349A patent/DE102012200349A1/de not_active Withdrawn
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2013
- 2013-01-10 CN CN201380013679.1A patent/CN104812762B/zh not_active Expired - Fee Related
- 2013-01-10 JP JP2014551609A patent/JP6251183B2/ja not_active Expired - Fee Related
- 2013-01-10 MX MX2014008201A patent/MX2014008201A/es not_active Application Discontinuation
- 2013-01-10 AP AP2014007844A patent/AP2014007844A0/xx unknown
- 2013-01-10 EA EA201491339A patent/EA025837B1/ru not_active IP Right Cessation
- 2013-01-10 KR KR1020147021969A patent/KR20140114416A/ko not_active Application Discontinuation
- 2013-01-10 US US14/371,046 patent/US20140357637A1/en not_active Abandoned
- 2013-01-10 PE PE2014001063A patent/PE20142293A1/es not_active Application Discontinuation
- 2013-01-10 NZ NZ626394A patent/NZ626394A/en not_active IP Right Cessation
- 2013-01-10 EP EP13700288.7A patent/EP2802592A1/de not_active Withdrawn
- 2013-01-10 SG SG11201403345UA patent/SG11201403345UA/en unknown
- 2013-01-10 WO PCT/EP2013/050381 patent/WO2013104703A1/de active Application Filing
- 2013-01-10 AU AU2013208968A patent/AU2013208968A1/en not_active Abandoned
- 2013-01-10 BR BR112014016971A patent/BR112014016971A8/pt not_active IP Right Cessation
- 2013-01-10 SG SG10201605655UA patent/SG10201605655UA/en unknown
- 2013-01-10 CA CA2860855A patent/CA2860855A1/en not_active Abandoned
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2014
- 2014-06-30 IL IL233460A patent/IL233460A0/en unknown
- 2014-07-03 CL CL2014001779A patent/CL2014001779A1/es unknown
- 2014-07-07 MA MA37178A patent/MA35844B1/fr unknown
- 2014-07-07 CU CU2014000082A patent/CU20140082A7/es unknown
- 2014-07-08 CR CR20140327A patent/CR20140327A/es unknown
- 2014-07-08 CO CO14146937A patent/CO7000776A2/es unknown
- 2014-07-08 DO DO2014000160A patent/DOP2014000160A/es unknown
- 2014-07-09 EC ECIEPI20148556A patent/ECSP14008556A/es unknown
- 2014-07-09 TN TNP2014000298A patent/TN2014000298A1/fr unknown
- 2014-07-10 GT GT201400147A patent/GT201400147A/es unknown
- 2014-07-10 ZA ZA2014/05042A patent/ZA201405042B/en unknown
- 2014-07-10 PH PH12014501595A patent/PH12014501595A1/en unknown
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2015
- 2015-06-12 US US14/738,148 patent/US9505786B2/en not_active Expired - Fee Related
- 2015-12-17 HK HK15112419.1A patent/HK1211585A1/xx unknown
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