BR112014016971A2 - pirimidinas e triazinas fundidas substituídas e seus usos - Google Patents

pirimidinas e triazinas fundidas substituídas e seus usos

Info

Publication number
BR112014016971A2
BR112014016971A2 BR112014016971A BR112014016971A BR112014016971A2 BR 112014016971 A2 BR112014016971 A2 BR 112014016971A2 BR 112014016971 A BR112014016971 A BR 112014016971A BR 112014016971 A BR112014016971 A BR 112014016971A BR 112014016971 A2 BR112014016971 A2 BR 112014016971A2
Authority
BR
Brazil
Prior art keywords
triazines
substituted fused
prophylaxis
treatment
fused pyrimidines
Prior art date
Application number
BR112014016971A
Other languages
English (en)
Other versions
BR112014016971A8 (pt
Inventor
Tersteegen Adrian
Lang Dieter
Wunder Frank
Redlich Gorden
Stasch Johannes-Peter
Follmann Markus
Griebenow Nils
Hübsch Walter
Original Assignee
Bayer Ip Gmbh
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47559479&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014016971(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ip Gmbh, Bayer Pharma AG filed Critical Bayer Ip Gmbh
Publication of BR112014016971A2 publication Critical patent/BR112014016971A2/pt
Publication of BR112014016971A8 publication Critical patent/BR112014016971A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

resumo da patente de invenção para: “pirimidinas e triazinas fundidas substituídas e seus usos” o presente pedido se refere a novas pirimidinas e triazinas fundidas substituídas, aos processos para a sua preparação, ao seu uso por si só ou em combinações para o tratamento e/ou profilaxia de doenças, e à sua utilização para a produção de medicamentos para o tratamento e/ou profilaxia de doenças, em particular para o tratamento e/ou profilaxia de distúrbios cardiovasculares.
BR112014016971A 2012-01-11 2013-01-10 pirimidinas e triazinas fundidas substituídas e seus usos BR112014016971A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012200349A DE102012200349A1 (de) 2012-01-11 2012-01-11 Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung
PCT/EP2013/050381 WO2013104703A1 (de) 2012-01-11 2013-01-10 Substituierte annellierte pyrimidine und triazine und ihre verwendung

Publications (2)

Publication Number Publication Date
BR112014016971A2 true BR112014016971A2 (pt) 2017-06-13
BR112014016971A8 BR112014016971A8 (pt) 2017-07-04

Family

ID=47559479

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014016971A BR112014016971A8 (pt) 2012-01-11 2013-01-10 pirimidinas e triazinas fundidas substituídas e seus usos

Country Status (29)

Country Link
US (2) US20140357637A1 (pt)
EP (1) EP2802592A1 (pt)
JP (1) JP6251183B2 (pt)
KR (1) KR20140114416A (pt)
CN (1) CN104812762B (pt)
AP (1) AP2014007844A0 (pt)
AU (1) AU2013208968A1 (pt)
BR (1) BR112014016971A8 (pt)
CA (1) CA2860855A1 (pt)
CL (1) CL2014001779A1 (pt)
CO (1) CO7000776A2 (pt)
CR (1) CR20140327A (pt)
CU (1) CU20140082A7 (pt)
DE (1) DE102012200349A1 (pt)
DO (1) DOP2014000160A (pt)
EA (1) EA025837B1 (pt)
EC (1) ECSP14008556A (pt)
GT (1) GT201400147A (pt)
HK (1) HK1211585A1 (pt)
IL (1) IL233460A0 (pt)
MA (1) MA35844B1 (pt)
MX (1) MX2014008201A (pt)
NZ (1) NZ626394A (pt)
PE (1) PE20142293A1 (pt)
PH (1) PH12014501595A1 (pt)
SG (2) SG11201403345UA (pt)
TN (1) TN2014000298A1 (pt)
WO (1) WO2013104703A1 (pt)
ZA (1) ZA201405042B (pt)

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EP2961754B1 (de) 2013-03-01 2016-11-16 Bayer Pharma Aktiengesellschaft Benzyl-substituierte pyrazolopyridine und ihre verwendung
AP2016008970A0 (en) 2013-07-10 2016-01-31 Bayer Pharma AG Benzyl-1h-pyrazolo[3,4-b]pyridines and use thereof

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CA2860855A1 (en) 2013-07-18
CL2014001779A1 (es) 2014-11-03
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US20150274754A1 (en) 2015-10-01
CU20140082A7 (es) 2014-10-30
ECSP14008556A (es) 2015-12-31
EP2802592A1 (de) 2014-11-19
PH12014501595A1 (en) 2014-10-08
CR20140327A (es) 2014-11-26
AP2014007844A0 (en) 2014-07-31
EA201491339A1 (ru) 2015-01-30
AU2013208968A1 (en) 2014-07-24
JP6251183B2 (ja) 2017-12-20
PE20142293A1 (es) 2014-12-19
SG11201403345UA (en) 2014-09-26
US20140357637A1 (en) 2014-12-04
DOP2014000160A (es) 2014-08-31
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HK1211585A1 (en) 2016-05-27
TN2014000298A1 (en) 2015-12-21
BR112014016971A8 (pt) 2017-07-04
WO2013104703A1 (de) 2013-07-18
MA35844B1 (fr) 2014-12-01
ZA201405042B (en) 2016-08-31
CN104812762A (zh) 2015-07-29
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US9505786B2 (en) 2016-11-29

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