ZA991590B - Indole derivatives and pharmaceutical compositions comprising the same. - Google Patents

Indole derivatives and pharmaceutical compositions comprising the same.

Info

Publication number
ZA991590B
ZA991590B ZA9901590A ZA991590A ZA991590B ZA 991590 B ZA991590 B ZA 991590B ZA 9901590 A ZA9901590 A ZA 9901590A ZA 991590 A ZA991590 A ZA 991590A ZA 991590 B ZA991590 B ZA 991590B
Authority
ZA
South Africa
Prior art keywords
same
pharmaceutical compositions
indole derivatives
indole
derivatives
Prior art date
Application number
ZA9901590A
Other languages
English (en)
Inventor
Makio Kitazawa
Toshiaki Yamaguchi
Hiroshi Miyata
Yukiyoshi Ajisawa
Original Assignee
Kissei Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceuticals Co Ltd filed Critical Kissei Pharmaceuticals Co Ltd
Publication of ZA991590B publication Critical patent/ZA991590B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
ZA9901590A 1998-02-27 1999-02-26 Indole derivatives and pharmaceutical compositions comprising the same. ZA991590B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9057298 1998-02-27

Publications (1)

Publication Number Publication Date
ZA991590B true ZA991590B (en) 1999-08-27

Family

ID=14002150

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901590A ZA991590B (en) 1998-02-27 1999-02-26 Indole derivatives and pharmaceutical compositions comprising the same.

Country Status (24)

Country Link
US (1) US6310086B1 (ko)
EP (1) EP1057813B1 (ko)
JP (1) JP4342101B2 (ko)
KR (1) KR100576207B1 (ko)
CN (1) CN1157375C (ko)
AR (1) AR014964A1 (ko)
AT (1) ATE264841T1 (ko)
AU (1) AU766088B2 (ko)
BR (1) BR9908301A (ko)
CA (1) CA2321547C (ko)
DE (1) DE69916586T2 (ko)
DK (1) DK1057813T3 (ko)
ES (1) ES2220043T3 (ko)
HK (1) HK1036974A1 (ko)
HU (1) HUP0100680A3 (ko)
NO (1) NO317257B1 (ko)
NZ (1) NZ506497A (ko)
PE (1) PE20000329A1 (ko)
PL (1) PL342477A1 (ko)
RU (1) RU2212404C2 (ko)
SK (1) SK12722000A3 (ko)
TW (2) TWI249525B (ko)
WO (1) WO1999043652A1 (ko)
ZA (1) ZA991590B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100576207B1 (ko) 1998-02-27 2006-05-03 깃세이 야쿠힌 고교 가부시키가이샤 인돌유도체 및 이 유도체를 함유하는 의약품 조성물
JP4634560B2 (ja) * 2000-01-14 2011-02-16 キッセイ薬品工業株式会社 光学活性なインドリン誘導体の製造方法およびその製造中間体
US6849655B2 (en) 2000-05-15 2005-02-01 Kissei Pharmaceutical Co., Ltd. Aqueous liquid formulations
EP1283199A4 (en) * 2000-05-16 2003-12-17 Takeda Chemical Industries Ltd MELANIN CONCENTRATION HORMONE ANTAGONIST
JP4921646B2 (ja) * 2001-03-08 2012-04-25 キッセイ薬品工業株式会社 1−(3−ベンジルオキシプロピル)−5−(2−置換プロピル)インドリン誘導体およびその使用方法
WO2003006061A1 (fr) * 2001-07-13 2003-01-23 Kissei Pharmaceutical Co., Ltd. Compositions de medicaments pour usage ophtalmologique
HU225505B1 (en) * 2002-09-09 2007-01-29 Richter Gedeon Vegyeszet Process for the preparation of r-(-)-tamsulosin hydrochloride and novel intermediates
PE20060373A1 (es) 2004-06-24 2006-04-29 Smithkline Beecham Corp Derivados 3-piperidinil-7-carboxamida-indazol como inhibidores de la actividad cinasa de ikk2
ES2362788T3 (es) * 2004-10-27 2011-07-13 Kissei Pharmaceutical Co., Ltd. Compuesto de indolina y proceso para la producción del mismo.
KR101326425B1 (ko) * 2005-06-21 2013-11-11 코와 가부시키가이샤 녹내장의 예방 또는 치료제
US8063071B2 (en) 2007-10-31 2011-11-22 GlaxoSmithKline, LLC Chemical compounds
US20100076010A1 (en) * 2007-02-26 2010-03-25 Concert Pharmaceuticals, Inc. Alpha 1a-adrenoceptor antagonists
US8013007B2 (en) * 2007-02-26 2011-09-06 Concert Pharmaceuticals, Inc. Alpha 1A-adrenoceptor antagonists
PE20081889A1 (es) 2007-03-23 2009-03-05 Smithkline Beecham Corp Indol carboxamidas como inhibidores de ikk2
JP2012520257A (ja) 2009-03-10 2012-09-06 グラクソ グループ リミテッド Ikk2阻害剤としてのインドール誘導体
CN104211631A (zh) * 2013-05-30 2014-12-17 中国科学院上海药物研究所 一类吲哚类化合物、其制备方法、药物组合物及应用
WO2016042441A1 (en) 2014-09-18 2016-03-24 Mankind Research Centre A novel process for the preparation of considerably pure silodosin
ES2607639B1 (es) 2015-09-30 2018-02-28 Urquima, S.A Sal de ácido maleico de un intermedio de silodosina

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5021410A (en) 1989-05-22 1991-06-04 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
EP0600675B1 (en) * 1992-12-02 1998-07-08 Kissei Pharmaceutical Co., Ltd. Indoline compounds for the treatment of dysuria
JP3331047B2 (ja) * 1994-06-01 2002-10-07 キッセイ薬品工業株式会社 インドリン誘導体
JP3331048B2 (ja) * 1994-06-01 2002-10-07 キッセイ薬品工業株式会社 インドール誘導体
JPH08143557A (ja) * 1994-11-24 1996-06-04 Toyobo Co Ltd 新規なフェニルピペラジン誘導体、その塩及びその溶媒和物
JPH0912563A (ja) * 1995-06-30 1997-01-14 Toyobo Co Ltd 新規ベンジルアルコ−ル誘導体、その製造方法およびその用途
WO1999015202A1 (fr) * 1997-09-22 1999-04-01 Kissei Pharmaceutical Co., Ltd. Medicaments contre la dysurie resultant d'une hypertrophie de la prostate
KR100576207B1 (ko) 1998-02-27 2006-05-03 깃세이 야쿠힌 고교 가부시키가이샤 인돌유도체 및 이 유도체를 함유하는 의약품 조성물

Also Published As

Publication number Publication date
TWI249525B (en) 2006-02-21
HK1036974A1 (en) 2002-01-25
AR014964A1 (es) 2001-04-11
SK12722000A3 (sk) 2001-03-12
KR20010041403A (ko) 2001-05-15
ES2220043T3 (es) 2004-12-01
PL342477A1 (en) 2001-06-04
NO317257B1 (no) 2004-09-27
CA2321547C (en) 2010-01-19
HUP0100680A2 (hu) 2001-08-28
KR100576207B1 (ko) 2006-05-03
CN1157375C (zh) 2004-07-14
NO20004277D0 (no) 2000-08-25
JP4342101B2 (ja) 2009-10-14
US6310086B1 (en) 2001-10-30
EP1057813B1 (en) 2004-04-21
ATE264841T1 (de) 2004-05-15
WO1999043652A1 (fr) 1999-09-02
AU766088B2 (en) 2003-10-09
TWI241293B (en) 2005-10-11
NZ506497A (en) 2004-12-24
PE20000329A1 (es) 2000-04-13
EP1057813A1 (en) 2000-12-06
NO20004277L (no) 2000-09-11
DE69916586D1 (de) 2004-05-27
AU2547899A (en) 1999-09-15
DE69916586T2 (de) 2004-09-16
CA2321547A1 (en) 1999-09-02
EP1057813A4 (en) 2001-11-21
BR9908301A (pt) 2000-10-31
RU2212404C2 (ru) 2003-09-20
DK1057813T3 (da) 2004-08-16
CN1291976A (zh) 2001-04-18
HUP0100680A3 (en) 2001-09-28

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