ZA988230B - Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists - Google Patents

Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists

Info

Publication number
ZA988230B
ZA988230B ZA988230A ZA988230A ZA988230B ZA 988230 B ZA988230 B ZA 988230B ZA 988230 A ZA988230 A ZA 988230A ZA 988230 A ZA988230 A ZA 988230A ZA 988230 B ZA988230 B ZA 988230B
Authority
ZA
South Africa
Prior art keywords
agonists
aromatic
substituted tetrahydro
prostaglandins useful
tetrahydro prostaglandins
Prior art date
Application number
ZA988230A
Other languages
English (en)
Inventor
John August Wos
Mitchell Anthony Delong
Jack S Amburgey
Biswanath De
Hayiyan George Dai
Yili Wang
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of ZA988230B publication Critical patent/ZA988230B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA988230A 1997-09-09 1998-09-09 Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists ZA988230B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5821797P 1997-09-09 1997-09-09

Publications (1)

Publication Number Publication Date
ZA988230B true ZA988230B (en) 1999-03-09

Family

ID=22015427

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA988230A ZA988230B (en) 1997-09-09 1998-09-09 Aromatic C16-C20-substituted tetrahydro prostaglandins useful as FP agonists

Country Status (24)

Country Link
US (1) US5977173A (es)
EP (1) EP1012136B1 (es)
JP (1) JP2001515882A (es)
KR (1) KR20010023839A (es)
CN (1) CN1269786A (es)
AR (1) AR013477A1 (es)
AT (1) ATE270660T1 (es)
AU (1) AU731153B2 (es)
BR (1) BR9811774A (es)
CA (1) CA2303764C (es)
CO (1) CO4970731A1 (es)
DE (1) DE69824966T2 (es)
ES (1) ES2223141T3 (es)
HU (1) HUP0100638A3 (es)
ID (1) ID23971A (es)
IL (1) IL134839A0 (es)
NO (1) NO20001141L (es)
NZ (1) NZ503735A (es)
PE (1) PE115499A1 (es)
PL (1) PL339212A1 (es)
SK (1) SK3372000A3 (es)
TR (1) TR200000671T2 (es)
WO (1) WO1999012895A1 (es)
ZA (1) ZA988230B (es)

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US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
KR100437873B1 (ko) * 2001-05-08 2004-06-26 연성정밀화학(주) 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질
US7351404B2 (en) 2002-02-04 2008-04-01 Allergan, Inc. Method of enhancing hair growth
US8758733B2 (en) 2002-02-04 2014-06-24 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US9216183B2 (en) 2002-02-04 2015-12-22 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
JP2008517941A (ja) 2004-10-21 2008-05-29 デューク・ユニバーシティー 眼科用薬剤
US20070254920A1 (en) * 2006-04-26 2007-11-01 Aerie Pharmaceuticals, Inc. Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use
US8455513B2 (en) 2007-01-10 2013-06-04 Aerie Pharmaceuticals, Inc. 6-aminoisoquinoline compounds
US7517912B1 (en) * 2007-10-31 2009-04-14 Meta Cosmetics, Llc Prostaglandin analog compositions and methods to treat epithelial-related conditions
WO2010039535A1 (en) * 2008-09-23 2010-04-08 Meta Cosmetics, Llc Compositions and methods to treat epithelial-related conditions
US8450344B2 (en) 2008-07-25 2013-05-28 Aerie Pharmaceuticals, Inc. Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
CA2739571A1 (en) 2008-10-29 2010-08-26 Aerie Pharmaceuticals, Inc. Amino acid salts of prostaglandins
US8637558B2 (en) 2008-12-30 2014-01-28 Industry-Academic Cooperation Foundation, Chosun University Thiazolidinedione derivative and use thereof
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
EP3828172A1 (en) 2009-05-01 2021-06-02 Aerie Pharmaceuticals, Inc. Dual mechanism inhibitors for the treatment of disease
US9149484B2 (en) 2009-11-09 2015-10-06 Allergan, Inc. Compositions and methods for stimulating hair growth
WO2011057129A2 (en) 2009-11-09 2011-05-12 Allergan, Inc. Compositions and methods for stimulating hair growth
US8859616B2 (en) 2011-01-21 2014-10-14 Allergan, Inc. Compounds and methods for enhancing hair growth
CN109528721B (zh) 2013-03-15 2021-10-01 爱瑞制药公司 联合治疗
US9643927B1 (en) 2015-11-17 2017-05-09 Aerie Pharmaceuticals, Inc. Process for the preparation of kinase inhibitors and intermediates thereof
CN109640966A (zh) 2016-08-31 2019-04-16 爱瑞制药公司 眼用组合物
MX2019011784A (es) 2017-03-31 2019-11-18 Aerie Pharmaceuticals Inc Compuestos de aril ciclopropil-amino-isoquinolinil amida.
CA3112391A1 (en) 2018-09-14 2020-03-19 Aerie Pharmaceuticals, Inc. Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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Also Published As

Publication number Publication date
JP2001515882A (ja) 2001-09-25
CN1269786A (zh) 2000-10-11
IL134839A0 (en) 2001-05-20
AR013477A1 (es) 2000-12-27
PL339212A1 (en) 2000-12-04
EP1012136A1 (en) 2000-06-28
NO20001141L (no) 2000-05-04
BR9811774A (pt) 2000-08-29
TR200000671T2 (tr) 2000-07-21
ATE270660T1 (de) 2004-07-15
CA2303764C (en) 2005-02-15
DE69824966T2 (de) 2005-04-07
DE69824966D1 (de) 2004-08-12
CA2303764A1 (en) 1999-03-18
AU731153B2 (en) 2001-03-22
HUP0100638A2 (hu) 2001-07-30
NO20001141D0 (no) 2000-03-06
WO1999012895A1 (en) 1999-03-18
AU9219398A (en) 1999-03-29
KR20010023839A (ko) 2001-03-26
CO4970731A1 (es) 2000-11-07
NZ503735A (en) 2001-05-25
SK3372000A3 (en) 2000-10-09
US5977173A (en) 1999-11-02
EP1012136B1 (en) 2004-07-07
PE115499A1 (es) 2000-02-03
ID23971A (id) 2000-06-14
ES2223141T3 (es) 2005-02-16
HUP0100638A3 (en) 2002-12-28

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