ZA9710576B - 2-imidazolinylaminoindazole compounds useful as alpha-2-adrenoceptor agonists - Google Patents

2-imidazolinylaminoindazole compounds useful as alpha-2-adrenoceptor agonists

Info

Publication number
ZA9710576B
ZA9710576B ZA9710576A ZA9710576A ZA9710576B ZA 9710576 B ZA9710576 B ZA 9710576B ZA 9710576 A ZA9710576 A ZA 9710576A ZA 9710576 A ZA9710576 A ZA 9710576A ZA 9710576 B ZA9710576 B ZA 9710576B
Authority
ZA
South Africa
Prior art keywords
imidazolinylaminoindazole
alpha
compounds useful
adrenoceptor agonists
adrenoceptor
Prior art date
Application number
ZA9710576A
Inventor
Thomas Lee Cupps
Sophie Eva Bogdan
Raymond Todd Henry
Russell James Sheldon
William Lee Seibel
Jeffrey Joseph Ares
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of ZA9710576B publication Critical patent/ZA9710576B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
ZA9710576A 1996-11-25 1997-11-25 2-imidazolinylaminoindazole compounds useful as alpha-2-adrenoceptor agonists ZA9710576B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3174096P 1996-11-25 1996-11-25
PCT/US1997/020551 WO1998023609A1 (en) 1996-11-25 1997-11-21 2-imidazolinylaminoindazole compounds useful as alpha-2 adrenoceptor agonists

Publications (1)

Publication Number Publication Date
ZA9710576B true ZA9710576B (en) 1998-09-16

Family

ID=21861136

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710576A ZA9710576B (en) 1996-11-25 1997-11-25 2-imidazolinylaminoindazole compounds useful as alpha-2-adrenoceptor agonists

Country Status (20)

Country Link
EP (1) EP0944620A1 (en)
JP (1) JP2001506599A (en)
KR (1) KR20000069104A (en)
CN (1) CN1244864A (en)
AR (1) AR010643A1 (en)
AU (1) AU5433998A (en)
BR (1) BR9713535A (en)
CA (1) CA2272644A1 (en)
CO (1) CO4910166A1 (en)
CZ (1) CZ183999A3 (en)
HU (1) HUP9904660A3 (en)
ID (1) ID22676A (en)
IL (1) IL130067A0 (en)
NO (1) NO992502L (en)
NZ (1) NZ335882A (en)
PE (1) PE47099A1 (en)
SK (1) SK69699A3 (en)
TR (1) TR199901542T2 (en)
WO (1) WO1998023609A1 (en)
ZA (1) ZA9710576B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9908175D0 (en) * 1999-04-09 1999-06-02 Lilly Co Eli Method of treating neurological disorders
US6433186B1 (en) 2000-08-16 2002-08-13 Astrazeneca Ab Amidino derivatives and their use as thormbin inhibitors
EP2226315A4 (en) 2007-12-28 2012-01-25 Carna Biosciences Inc 2-aminoquinazoline derivative
WO2010074753A1 (en) 2008-12-23 2010-07-01 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
CN112538074A (en) * 2020-12-24 2021-03-23 艾希尔(深圳)药物研发有限公司 Preparation method of debrominated impurities of brimonidine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH641782A5 (en) * 1978-12-07 1984-03-15 Siegfried Ag 1H- and 2H-indazole derivatives
US4526898A (en) * 1980-09-05 1985-07-02 Siegfried Aktiengesselschaft Antihypertensive 4-(2-imidazolin-2-yl-amino)-2-methyl-indazole
CN1137755A (en) * 1993-12-17 1996-12-11 普罗克特和甘保尔公司 6-(2-imidazolinylamino) quinoxaling compounds useful as alpha-2 adrenoceptor agonists
US5478858A (en) * 1993-12-17 1995-12-26 The Procter & Gamble Company 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists

Also Published As

Publication number Publication date
NO992502D0 (en) 1999-05-25
JP2001506599A (en) 2001-05-22
CZ183999A3 (en) 1999-11-17
BR9713535A (en) 2000-03-21
PE47099A1 (en) 1999-06-12
SK69699A3 (en) 2000-06-12
CA2272644A1 (en) 1998-06-04
AU5433998A (en) 1998-06-22
CN1244864A (en) 2000-02-16
TR199901542T2 (en) 2000-01-21
KR20000069104A (en) 2000-11-25
HUP9904660A2 (en) 2000-06-28
NO992502L (en) 1999-07-26
NZ335882A (en) 2000-12-22
IL130067A0 (en) 2000-02-29
EP0944620A1 (en) 1999-09-29
CO4910166A1 (en) 2000-04-24
WO1998023609A1 (en) 1998-06-04
HUP9904660A3 (en) 2002-02-28
ID22676A (en) 1999-12-09
AR010643A1 (en) 2000-06-28

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