HUP9904660A3 - 2-imidazolinylaminoindazole compounds useful as alpha-2 adrenoceptor agonists - Google Patents
2-imidazolinylaminoindazole compounds useful as alpha-2 adrenoceptor agonistsInfo
- Publication number
- HUP9904660A3 HUP9904660A3 HU9904660A HUP9904660A HUP9904660A3 HU P9904660 A3 HUP9904660 A3 HU P9904660A3 HU 9904660 A HU9904660 A HU 9904660A HU P9904660 A HUP9904660 A HU P9904660A HU P9904660 A3 HUP9904660 A3 HU P9904660A3
- Authority
- HU
- Hungary
- Prior art keywords
- imidazolinylaminoindazole
- alpha
- compounds useful
- adrenoceptor agonists
- adrenoceptor
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
- 102000030484 alpha-2 Adrenergic Receptor Human genes 0.000 title 1
- 108020004101 alpha-2 Adrenergic Receptor Proteins 0.000 title 1
- RGVBAADKKPKGQR-UHFFFAOYSA-N n-(4,5-dihydroimidazol-1-yl)-1h-indazol-3-amine Chemical class C1=NCCN1NC1=NNC2=CC=CC=C12 RGVBAADKKPKGQR-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3174096P | 1996-11-25 | 1996-11-25 | |
PCT/US1997/020551 WO1998023609A1 (en) | 1996-11-25 | 1997-11-21 | 2-imidazolinylaminoindazole compounds useful as alpha-2 adrenoceptor agonists |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9904660A2 HUP9904660A2 (en) | 2000-06-28 |
HUP9904660A3 true HUP9904660A3 (en) | 2002-02-28 |
Family
ID=21861136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9904660A HUP9904660A3 (en) | 1996-11-25 | 1997-11-21 | 2-imidazolinylaminoindazole compounds useful as alpha-2 adrenoceptor agonists |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0944620A1 (en) |
JP (1) | JP2001506599A (en) |
KR (1) | KR20000069104A (en) |
CN (1) | CN1244864A (en) |
AR (1) | AR010643A1 (en) |
AU (1) | AU5433998A (en) |
BR (1) | BR9713535A (en) |
CA (1) | CA2272644A1 (en) |
CO (1) | CO4910166A1 (en) |
CZ (1) | CZ183999A3 (en) |
HU (1) | HUP9904660A3 (en) |
ID (1) | ID22676A (en) |
IL (1) | IL130067A0 (en) |
NO (1) | NO992502L (en) |
NZ (1) | NZ335882A (en) |
PE (1) | PE47099A1 (en) |
SK (1) | SK69699A3 (en) |
TR (1) | TR199901542T2 (en) |
WO (1) | WO1998023609A1 (en) |
ZA (1) | ZA9710576B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9908175D0 (en) * | 1999-04-09 | 1999-06-02 | Lilly Co Eli | Method of treating neurological disorders |
US6433186B1 (en) | 2000-08-16 | 2002-08-13 | Astrazeneca Ab | Amidino derivatives and their use as thormbin inhibitors |
EP2226315A4 (en) | 2007-12-28 | 2012-01-25 | Carna Biosciences Inc | 2-aminoquinazoline derivative |
US8555875B2 (en) | 2008-12-23 | 2013-10-15 | Map Pharmaceuticals, Inc. | Inhalation devices and related methods for administration of sedative hypnotic compounds |
CN112538074A (en) * | 2020-12-24 | 2021-03-23 | 艾希尔(深圳)药物研发有限公司 | Preparation method of debrominated impurities of brimonidine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH641782A5 (en) * | 1978-12-07 | 1984-03-15 | Siegfried Ag | 1H- and 2H-indazole derivatives |
US4526898A (en) * | 1980-09-05 | 1985-07-02 | Siegfried Aktiengesselschaft | Antihypertensive 4-(2-imidazolin-2-yl-amino)-2-methyl-indazole |
US5478858A (en) * | 1993-12-17 | 1995-12-26 | The Procter & Gamble Company | 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists |
DE69425334T2 (en) * | 1993-12-17 | 2001-02-08 | Procter & Gamble | 6- (2-IMIDAZOLINYLAMINO) CHINOXALINE COMPOUNDS AS ALPHA-2 ADRENORE RECEPTORAGONISTS |
-
1997
- 1997-11-21 CN CN97181453A patent/CN1244864A/en active Pending
- 1997-11-21 ID IDW990412A patent/ID22676A/en unknown
- 1997-11-21 CA CA002272644A patent/CA2272644A1/en not_active Abandoned
- 1997-11-21 BR BR9713535A patent/BR9713535A/en unknown
- 1997-11-21 CZ CZ991839A patent/CZ183999A3/en unknown
- 1997-11-21 IL IL13006797A patent/IL130067A0/en unknown
- 1997-11-21 WO PCT/US1997/020551 patent/WO1998023609A1/en not_active Application Discontinuation
- 1997-11-21 NZ NZ335882A patent/NZ335882A/en unknown
- 1997-11-21 TR TR1999/01542T patent/TR199901542T2/en unknown
- 1997-11-21 HU HU9904660A patent/HUP9904660A3/en unknown
- 1997-11-21 AU AU54339/98A patent/AU5433998A/en not_active Abandoned
- 1997-11-21 JP JP52468698A patent/JP2001506599A/en active Pending
- 1997-11-21 KR KR1019997004569A patent/KR20000069104A/en not_active Application Discontinuation
- 1997-11-21 EP EP97948238A patent/EP0944620A1/en not_active Withdrawn
- 1997-11-24 CO CO97068615A patent/CO4910166A1/en unknown
- 1997-11-25 AR ARP970105524A patent/AR010643A1/en unknown
- 1997-11-25 PE PE1997001067A patent/PE47099A1/en not_active Application Discontinuation
- 1997-11-25 ZA ZA9710576A patent/ZA9710576B/en unknown
-
1999
- 1999-05-25 SK SK696-99A patent/SK69699A3/en unknown
- 1999-05-25 NO NO992502A patent/NO992502L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUP9904660A2 (en) | 2000-06-28 |
ZA9710576B (en) | 1998-09-16 |
SK69699A3 (en) | 2000-06-12 |
PE47099A1 (en) | 1999-06-12 |
AU5433998A (en) | 1998-06-22 |
JP2001506599A (en) | 2001-05-22 |
TR199901542T2 (en) | 2000-01-21 |
BR9713535A (en) | 2000-03-21 |
NO992502L (en) | 1999-07-26 |
NO992502D0 (en) | 1999-05-25 |
CZ183999A3 (en) | 1999-11-17 |
ID22676A (en) | 1999-12-09 |
KR20000069104A (en) | 2000-11-25 |
WO1998023609A1 (en) | 1998-06-04 |
NZ335882A (en) | 2000-12-22 |
IL130067A0 (en) | 2000-02-29 |
AR010643A1 (en) | 2000-06-28 |
CN1244864A (en) | 2000-02-16 |
CA2272644A1 (en) | 1998-06-04 |
CO4910166A1 (en) | 2000-04-24 |
EP0944620A1 (en) | 1999-09-29 |
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