ZA974981B - A novel composition for transdermal administration of an estrogen, a progestin or a mixture thereof. - Google Patents
A novel composition for transdermal administration of an estrogen, a progestin or a mixture thereof.Info
- Publication number
- ZA974981B ZA974981B ZA9704981A ZA974981A ZA974981B ZA 974981 B ZA974981 B ZA 974981B ZA 9704981 A ZA9704981 A ZA 9704981A ZA 974981 A ZA974981 A ZA 974981A ZA 974981 B ZA974981 B ZA 974981B
- Authority
- ZA
- South Africa
- Prior art keywords
- progestin
- estrogen
- mixture
- transdermal administration
- novel composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001152A IT1283102B1 (it) | 1996-06-06 | 1996-06-06 | Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA974981B true ZA974981B (en) | 1998-01-23 |
Family
ID=11374388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9704981A ZA974981B (en) | 1996-06-06 | 1997-06-05 | A novel composition for transdermal administration of an estrogen, a progestin or a mixture thereof. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5891462A (enExample) |
| EP (1) | EP0811381B1 (enExample) |
| JP (1) | JP4293293B2 (enExample) |
| AR (1) | AR007530A1 (enExample) |
| AT (1) | ATE238801T1 (enExample) |
| AU (1) | AU712465B2 (enExample) |
| CA (1) | CA2207144C (enExample) |
| DE (1) | DE69721377T2 (enExample) |
| DK (1) | DK0811381T3 (enExample) |
| ES (1) | ES2198516T3 (enExample) |
| IT (1) | IT1283102B1 (enExample) |
| NZ (1) | NZ328021A (enExample) |
| TW (1) | TW565462B (enExample) |
| ZA (1) | ZA974981B (enExample) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19701949A1 (de) * | 1997-01-13 | 1998-07-16 | Jenapharm Gmbh | Transdermales therapeutisches System |
| EP1510213B1 (en) * | 1997-11-10 | 2008-12-31 | Strakan International Limited | Penetration enhancing and irritation reducing systems comprising testosterone |
| JP3987655B2 (ja) * | 1998-03-03 | 2007-10-10 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗痴呆薬を含有した経皮適用製剤又は坐剤 |
| FR2776191B1 (fr) * | 1998-03-23 | 2002-05-31 | Theramex | Composition hormonale topique a effet systemique |
| GB9828480D0 (en) * | 1998-12-24 | 1999-02-17 | Dermatech Limited | Transdermal drug delivery system |
| WO2001013957A2 (en) | 1999-08-24 | 2001-03-01 | Cellgate, Inc. | Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties |
| DE10019171A1 (de) * | 2000-04-07 | 2001-10-18 | Schering Ag | Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe |
| US7179483B2 (en) * | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| DE60143477D1 (de) * | 2000-04-26 | 2010-12-30 | Watson Pharmaceuticals Inc | Verminderung der nebenwirkungen bei der oxybutynin-therapie |
| US7029694B2 (en) * | 2000-04-26 | 2006-04-18 | Watson Laboratories, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| DE10025970C2 (de) * | 2000-05-25 | 2002-04-25 | Lohmann Therapie Syst Lts | Estrogenhaltiges Pflaster mit einem Wirkstoffreservoir auf der Basis von Ethylcellulose und einem Ethylen-Vinylacetat-Vinylpyrrolidon-Copolymer und seine Verwendung |
| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| EP1307232B1 (en) * | 2000-08-03 | 2007-03-07 | Antares Pharma IPL AG | Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| WO2005039531A1 (en) * | 2003-10-10 | 2005-05-06 | Antares Pharma Ipl Ag | Transdermal pharmaceutical formulation for minimizing skin residues |
| US20070225379A1 (en) * | 2001-08-03 | 2007-09-27 | Carrara Dario Norberto R | Transdermal delivery of systemically active central nervous system drugs |
| US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
| US20040002482A1 (en) * | 2000-08-30 | 2004-01-01 | Dudley Robert E. | Androgen pharmaceutical composition and method for treating depression |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20030027804A1 (en) * | 2001-06-27 | 2003-02-06 | Van Der Hoop Roland Gerritsen | Therapeutic combinations for the treatment of hormone deficiencies |
| US20040062794A1 (en) * | 2002-09-30 | 2004-04-01 | Lee Shulman | 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy |
| FR2848112B1 (fr) * | 2002-12-10 | 2007-02-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse comprenant au moins un progestatif et/ou au moins un oestrogene, son procede de preparation et ses utilisations |
| US7572780B2 (en) * | 2003-01-21 | 2009-08-11 | Dimera, Incorporated | Method and kit for reducing the symptoms of peripheral vascular disease |
| FR2851470B1 (fr) * | 2003-02-20 | 2007-11-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
| US20040253326A1 (en) * | 2003-02-25 | 2004-12-16 | Mesko Charles A. | Composition for increasing levels of hormones and a method for preparation of said composition |
| CN1997357A (zh) * | 2003-03-11 | 2007-07-11 | 安塔雷斯制药Ipl股份公司 | 透皮或透粘膜应用活性剂的用途和制剂 |
| US7858607B2 (en) * | 2003-03-14 | 2010-12-28 | Mamchur Stephen A | System for use by compounding pharmacists to produce hormone replacement medicine customized for each consumer |
| US7879357B2 (en) | 2003-04-28 | 2011-02-01 | Bayer Schering Pharma Ag | Pharmaceutical composition in the form of a hydrogel for transdermal administration of active ingredients |
| JO2492B1 (en) | 2003-04-28 | 2009-10-05 | شيرينج ايه جي | A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients |
| US7387788B1 (en) | 2003-10-10 | 2008-06-17 | Antares Pharma Ipl Ag | Pharmaceutical compositions of nicotine and methods of use thereof |
| US7780973B2 (en) * | 2003-12-15 | 2010-08-24 | Ethicon Endo-Surgery, Inc. | Method and device for minimally invasive implantation of biomaterial |
| US7425340B2 (en) | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
| JP4969050B2 (ja) * | 2005-01-07 | 2012-07-04 | ロート製薬株式会社 | 皮膚外用剤 |
| JP2007045808A (ja) * | 2005-01-07 | 2007-02-22 | Rohto Pharmaceut Co Ltd | 皮膚外用剤 |
| US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
| WO2007124250A2 (en) | 2006-04-21 | 2007-11-01 | Antares Pharma Ipl Ag | Methods of treating hot flashes with formulations for transdermal or transmucosal application |
| US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
| KR100699582B1 (ko) | 2005-07-11 | 2007-03-23 | 삼성전기주식회사 | 출력 버퍼회로 |
| PL2450041T3 (pl) | 2005-10-12 | 2019-02-28 | Unimed Pharmaceuticals, Llc | Ulepszony żel zawierający testosteron do zastosowania do leczenia hipogonadyzmu |
| US20070254036A1 (en) * | 2006-04-13 | 2007-11-01 | Besins Healthcare Sa | Treatment of menopause associated symptoms |
| WO2008067991A2 (en) * | 2006-12-08 | 2008-06-12 | Antares Pharma Ipl Ag | Skin-friendly drug complexes for transdermal administration |
| WO2009037813A1 (ja) * | 2007-09-20 | 2009-03-26 | Shiseido Company, Ltd. | 経皮吸収製剤 |
| WO2010008600A1 (en) * | 2008-07-16 | 2010-01-21 | Dermworx Incorporated | Topical drug delivery system |
| US10080760B2 (en) | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
| FR2954980B1 (fr) | 2010-01-04 | 2012-02-10 | Guillemot Corp | Joystick a ressorts de compensation, procede de fabrication et manette correspondants. |
| US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| AR086400A1 (es) | 2011-05-13 | 2013-12-11 | Trimel Pharmaceuticals Corp | Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo |
| US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
| JP5820206B2 (ja) | 2011-09-13 | 2015-11-24 | 日東電工株式会社 | 経皮吸収促進用組成物および貼付製剤 |
| JP5820207B2 (ja) | 2011-09-13 | 2015-11-24 | 日東電工株式会社 | 経皮吸収促進用組成物および貼付製剤 |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| EP2782584B1 (en) | 2011-11-23 | 2021-06-09 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
| KR20170005819A (ko) | 2014-05-22 | 2017-01-16 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 천연 복합 호르몬 대체 제형 및 요법 |
| MX2016013693A (es) * | 2014-07-29 | 2017-10-31 | Therapeuticsmd Inc | Crema transdermica. |
| US10264664B1 (en) | 2015-06-04 | 2019-04-16 | Vlt, Inc. | Method of electrically interconnecting circuit assemblies |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10493049B2 (en) | 2016-02-10 | 2019-12-03 | Niracle LLC | Applicator-based transdermal drug delivery system for administration of drugs in combination with topical formulations |
| BR112018070199A2 (pt) | 2016-04-01 | 2019-01-29 | Therapeuticsmd Inc | composição farmacêutica de hormônio esteroide |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| US10556717B2 (en) | 2017-03-10 | 2020-02-11 | E-Pac Packaging Services Co. Ltd. | Packaging assembly comprising a tightening portion, a box portion, a flexible strip and a pair of securing members |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| WO2023081539A1 (en) | 2021-11-08 | 2023-05-11 | Weiyong Li | Transdermal drug delivery system for delivering a drug to a patient |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4315925A (en) * | 1980-05-30 | 1982-02-16 | University Of Kentucky Research Foundation | Method of administering natural female sex hormones |
| FR2518879A1 (fr) * | 1981-12-30 | 1983-07-01 | Besins Jean | Medicament a base d'oestradiol pour le traitement de la pathologie menopausique |
| US5145682A (en) * | 1986-05-30 | 1992-09-08 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration |
| US5023084A (en) * | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| US4788062A (en) * | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
| CH674618A5 (enExample) * | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
| US4942158A (en) * | 1988-10-13 | 1990-07-17 | Eastman Kodak | Transdermal steroid penetrant compositions and methods utilizing isopropanol and isobutanol |
| ATE132751T1 (de) * | 1988-10-27 | 1996-01-15 | Schering Ag | Mittel zur transdermalen applikation enthaltend gestoden |
| US4973468A (en) * | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
| ATE107517T1 (de) * | 1989-05-25 | 1994-07-15 | Takeda Chemical Industries Ltd | Transdermales therapeutisches mittel. |
| US4956171A (en) * | 1989-07-21 | 1990-09-11 | Paco Pharmaceutical Services, Inc. | Transdermal drug delivery using a dual permeation enhancer and method of performing the same |
| SE8904296D0 (sv) * | 1989-12-21 | 1989-12-21 | Pharmacia Ab | Transdermal system |
| JP3046346B2 (ja) * | 1990-03-12 | 2000-05-29 | 昭和電工株式会社 | 外用剤基剤又は補助剤とそれを含有する人又は動物の外用剤 |
| US5453279A (en) * | 1992-04-21 | 1995-09-26 | Tbs Laboratories, Inc. | Enhancing transdermal absorption compositions; transdermal dosage form; and process |
-
1996
- 1996-06-06 IT IT96MI001152A patent/IT1283102B1/it active IP Right Grant
-
1997
- 1997-06-04 DE DE69721377T patent/DE69721377T2/de not_active Expired - Lifetime
- 1997-06-04 DK DK97108989T patent/DK0811381T3/da active
- 1997-06-04 AT AT97108989T patent/ATE238801T1/de active
- 1997-06-04 ES ES97108989T patent/ES2198516T3/es not_active Expired - Lifetime
- 1997-06-04 EP EP97108989A patent/EP0811381B1/en not_active Expired - Lifetime
- 1997-06-05 CA CA002207144A patent/CA2207144C/en not_active Expired - Lifetime
- 1997-06-05 NZ NZ328021A patent/NZ328021A/en not_active IP Right Cessation
- 1997-06-05 JP JP18569597A patent/JP4293293B2/ja not_active Expired - Fee Related
- 1997-06-05 US US08/869,982 patent/US5891462A/en not_active Expired - Lifetime
- 1997-06-05 ZA ZA9704981A patent/ZA974981B/xx unknown
- 1997-06-05 AU AU24729/97A patent/AU712465B2/en not_active Ceased
- 1997-06-06 TW TW086107807A patent/TW565462B/zh not_active IP Right Cessation
- 1997-06-06 AR ARP970102497A patent/AR007530A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| TW565462B (en) | 2003-12-11 |
| CA2207144A1 (en) | 1997-12-06 |
| DE69721377T2 (de) | 2004-04-01 |
| JPH1072351A (ja) | 1998-03-17 |
| US5891462A (en) | 1999-04-06 |
| ITMI961152A1 (it) | 1997-12-06 |
| DK0811381T3 (da) | 2003-08-25 |
| DE69721377D1 (de) | 2003-06-05 |
| CA2207144C (en) | 2008-07-29 |
| ATE238801T1 (de) | 2003-05-15 |
| AR007530A1 (es) | 1999-11-10 |
| EP0811381B1 (en) | 2003-05-02 |
| AU2472997A (en) | 1997-12-11 |
| ES2198516T3 (es) | 2004-02-01 |
| EP0811381A1 (en) | 1997-12-10 |
| AU712465B2 (en) | 1999-11-04 |
| ITMI961152A0 (it) | 1996-06-06 |
| JP4293293B2 (ja) | 2009-07-08 |
| IT1283102B1 (it) | 1998-04-07 |
| NZ328021A (en) | 1997-11-24 |
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