AR007530A1 - Gel para la administracion transdermica - Google Patents

Gel para la administracion transdermica

Info

Publication number
AR007530A1
AR007530A1 ARP970102497A ARP970102497A AR007530A1 AR 007530 A1 AR007530 A1 AR 007530A1 AR P970102497 A ARP970102497 A AR P970102497A AR P970102497 A ARP970102497 A AR P970102497A AR 007530 A1 AR007530 A1 AR 007530A1
Authority
AR
Argentina
Prior art keywords
agent
gel
combination
glycol
transdermic administration
Prior art date
Application number
ARP970102497A
Other languages
English (en)
Original Assignee
Permatec N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Permatec N V filed Critical Permatec N V
Publication of AR007530A1 publication Critical patent/AR007530A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Abstract

Una composición farmaceútica en forma de gel apropiada para la administración transdermica de un agente activo de la clase de estrógenos yprogestina o de una mezcla de ambos, compuesta por: a) un intensificador de permeabilidad delo s agentes acitvos previamente mencionados, una combinacióncompuesta fundamentalmente por un alcohol alifático cuya fórmula general es CH3 (CH2)n CH2OH, en la cual n = 8-16 y por un éter monoalquil de glicoldietileno; b) un excipiente o agentecat alizador, una combinación de un alkanol de 2+4 C átomos, un glicol y agua; c) una amina terciaria como agenteespesante y neutralizante.
ARP970102497A 1996-06-06 1997-06-06 Gel para la administracion transdermica AR007530A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI001152A IT1283102B1 (it) 1996-06-06 1996-06-06 Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele

Publications (1)

Publication Number Publication Date
AR007530A1 true AR007530A1 (es) 1999-11-10

Family

ID=11374388

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970102497A AR007530A1 (es) 1996-06-06 1997-06-06 Gel para la administracion transdermica

Country Status (14)

Country Link
US (1) US5891462A (es)
EP (1) EP0811381B1 (es)
JP (1) JP4293293B2 (es)
AR (1) AR007530A1 (es)
AT (1) ATE238801T1 (es)
AU (1) AU712465B2 (es)
CA (1) CA2207144C (es)
DE (1) DE69721377T2 (es)
DK (1) DK0811381T3 (es)
ES (1) ES2198516T3 (es)
IT (1) IT1283102B1 (es)
NZ (1) NZ328021A (es)
TW (1) TW565462B (es)
ZA (1) ZA974981B (es)

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Also Published As

Publication number Publication date
IT1283102B1 (it) 1998-04-07
DE69721377D1 (de) 2003-06-05
TW565462B (en) 2003-12-11
AU2472997A (en) 1997-12-11
CA2207144A1 (en) 1997-12-06
DK0811381T3 (da) 2003-08-25
ZA974981B (en) 1998-01-23
AU712465B2 (en) 1999-11-04
JP4293293B2 (ja) 2009-07-08
NZ328021A (en) 1997-11-24
DE69721377T2 (de) 2004-04-01
JPH1072351A (ja) 1998-03-17
ATE238801T1 (de) 2003-05-15
ITMI961152A0 (it) 1996-06-06
ITMI961152A1 (it) 1997-12-06
EP0811381A1 (en) 1997-12-10
CA2207144C (en) 2008-07-29
ES2198516T3 (es) 2004-02-01
US5891462A (en) 1999-04-06
EP0811381B1 (en) 2003-05-02

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