ZA962598B - Cyclic peptide antifungal agents. - Google Patents

Cyclic peptide antifungal agents.

Info

Publication number
ZA962598B
ZA962598B ZA9602598A ZA962598A ZA962598B ZA 962598 B ZA962598 B ZA 962598B ZA 9602598 A ZA9602598 A ZA 9602598A ZA 962598 A ZA962598 A ZA 962598A ZA 962598 B ZA962598 B ZA 962598B
Authority
ZA
South Africa
Prior art keywords
antifungal agents
cyclic peptide
peptide antifungal
cyclic
agents
Prior art date
Application number
ZA9602598A
Other languages
English (en)
Inventor
Peter Stanley Borromeo
Michael John Rodriguez
Junior William Wilson Turner
Venkatraghaven Vasudevan
James Andrew Jamison
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA962598B publication Critical patent/ZA962598B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9602598A 1995-04-07 1996-04-01 Cyclic peptide antifungal agents. ZA962598B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41834195A 1995-04-07 1995-04-07

Publications (1)

Publication Number Publication Date
ZA962598B true ZA962598B (en) 1997-10-01

Family

ID=23657711

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9602598A ZA962598B (en) 1995-04-07 1996-04-01 Cyclic peptide antifungal agents.

Country Status (29)

Country Link
US (1) US5646111A (de)
EP (1) EP0736541B1 (de)
JP (1) JPH11504005A (de)
KR (1) KR19980703646A (de)
CN (1) CN1185739A (de)
AR (2) AR004170A1 (de)
AT (1) ATE228535T1 (de)
AU (1) AU702841B2 (de)
BR (1) BR9604906A (de)
CA (1) CA2217048A1 (de)
CO (1) CO4700480A1 (de)
CZ (1) CZ291702B6 (de)
DE (1) DE69624966T2 (de)
EA (1) EA000464B1 (de)
ES (1) ES2187617T3 (de)
HU (1) HUP9800809A3 (de)
IL (1) IL117749A (de)
IN (1) IN181897B (de)
MX (1) MX9707611A (de)
MY (1) MY132116A (de)
NO (1) NO974562L (de)
NZ (1) NZ305735A (de)
PE (1) PE39097A1 (de)
PL (1) PL322821A1 (de)
TR (1) TR199701122T1 (de)
UA (1) UA46759C2 (de)
WO (1) WO1996031228A1 (de)
YU (1) YU22496A (de)
ZA (1) ZA962598B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
CA2244238A1 (en) * 1996-02-01 1997-08-07 Eli Lilly And Company Cyclic peptide antifungal agents
CA2301184A1 (en) * 1997-08-04 1999-02-11 Eli Lilly And Company Cyclic peptide antifungal agents
UA72200C2 (uk) * 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
MA26663A1 (fr) 1998-07-23 2004-12-20 Hoffmann La Roche Nouvelles aerothricines et leurs applications antifongiques
WO2000011023A2 (en) 1998-08-20 2000-03-02 Eli Lilly And Company Ring modified cyclic peptide analogs
DK1137663T3 (da) 1998-12-09 2007-01-08 Lilly Co Eli Oprensning af Echinocandin-cyclopeptidforbindelser
CN1345230A (zh) 1999-03-03 2002-04-17 伊莱利利公司 口服ecb药物制剂和药物组合物的制备方法
KR20020002476A (ko) 1999-03-03 2002-01-09 피터 지. 스트링거 결정질 에키노칸딘 암모늄염의 형성 및 음이온 교환
BR0008712A (pt) 1999-03-03 2001-12-26 Lilly Co Eli Complexos equinocandina/carboidrato
CN100335122C (zh) * 1999-03-03 2007-09-05 伊莱利利公司 含有成胶束表面活性剂的棘白菌素药物制剂
FR2794747B1 (fr) * 1999-06-09 2004-04-16 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
ES2240394T3 (es) 2000-01-17 2005-10-16 Basilea Pharmaceutica Ag Analogos de aerotricina, su preparacion y uso.
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
CN101602795B (zh) * 2009-07-20 2011-12-21 中国人民解放军第二军医大学 环六脂肽胺类抗真菌化合物及其盐类和制备方法
CN103570530B (zh) * 2012-07-26 2016-08-10 鲁南新时代生物技术有限公司 一种阿尼芬净侧链中间体的制备方法
CN104003895B (zh) * 2014-05-29 2016-02-24 黑龙江大学 一种钯催化的串联反应合成三联苯类化合物的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320052A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) * 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5049546A (en) * 1990-03-19 1991-09-17 Merck & Co., Inc. Antibiotic agents
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IE910892A1 (en) * 1990-03-19 1991-09-25 Merck & Co Inc Lipopeptide compounds
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Peptides, of antibiotics, processes for their preparation and pharmaceutical preparations containing them
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
US5233023A (en) * 1991-07-30 1993-08-03 Merck & Co., Inc. Process for phosphate ester compounds of certain cyclohexapeptides
IL105048A (en) * 1992-03-19 2001-06-14 Eli Lilly And Company U S Antifungal substances of the cyclic peptide type and a process for their preparation

Also Published As

Publication number Publication date
DE69624966D1 (de) 2003-01-09
NZ305735A (en) 1999-01-28
NO974562D0 (no) 1997-10-02
DE69624966T2 (de) 2003-03-27
AR002731A1 (es) 1998-04-29
EP0736541B1 (de) 2002-11-27
CZ291702B6 (cs) 2003-05-14
PL322821A1 (en) 1998-02-16
WO1996031228A1 (en) 1996-10-10
HUP9800809A3 (en) 1998-12-28
CZ310297A3 (cs) 1998-06-17
IL117749A (en) 2000-06-01
CO4700480A1 (es) 1998-12-29
AU702841B2 (en) 1999-03-04
ATE228535T1 (de) 2002-12-15
NO974562L (no) 1997-11-28
PE39097A1 (es) 1997-10-13
JPH11504005A (ja) 1999-04-06
IN181897B (de) 1998-10-24
CA2217048A1 (en) 1996-10-10
EP0736541A1 (de) 1996-10-09
TR199701122T1 (xx) 1998-02-21
HUP9800809A2 (hu) 1998-08-28
US5646111A (en) 1997-07-08
KR19980703646A (ko) 1998-12-05
AR004170A1 (es) 1998-11-04
BR9604906A (pt) 1998-07-21
MY132116A (en) 2007-09-28
EA199700307A1 (ru) 1998-04-30
EA000464B1 (ru) 1999-08-26
UA46759C2 (uk) 2002-06-17
IL117749A0 (en) 1996-08-04
YU22496A (sh) 1999-06-15
ES2187617T3 (es) 2003-06-16
CN1185739A (zh) 1998-06-24
MX9707611A (es) 1997-12-31
AU5383496A (en) 1996-10-23

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