ZA932399B - Peptides with modifications at the N terminus. - Google Patents

Peptides with modifications at the N terminus.

Info

Publication number
ZA932399B
ZA932399B ZA932399A ZA932399A ZA932399B ZA 932399 B ZA932399 B ZA 932399B ZA 932399 A ZA932399 A ZA 932399A ZA 932399 A ZA932399 A ZA 932399A ZA 932399 B ZA932399 B ZA 932399B
Authority
ZA
South Africa
Prior art keywords
radical
direct linkage
formula
cyclo
hetero
Prior art date
Application number
ZA932399A
Other languages
English (en)
Inventor
Gerhard Breipohl
Stephan Henke
Jochem Knolle
Bernward Schoelkens
Hans-Georg Alpermann
Hermann Gerhards
Klaus Wirth
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA932399B publication Critical patent/ZA932399B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/18Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transceivers (AREA)
  • Mobile Radio Communication Systems (AREA)
ZA932399A 1992-04-04 1993-04-02 Peptides with modifications at the N terminus. ZA932399B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4211406 1992-04-04

Publications (1)

Publication Number Publication Date
ZA932399B true ZA932399B (en) 1993-10-19

Family

ID=6456125

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA932399A ZA932399B (en) 1992-04-04 1993-04-02 Peptides with modifications at the N terminus.

Country Status (25)

Country Link
US (1) US5597803A (xx)
EP (1) EP0564972B1 (xx)
JP (1) JP3426639B2 (xx)
KR (1) KR100273825B1 (xx)
CN (1) CN1040330C (xx)
AT (1) ATE183197T1 (xx)
AU (1) AU667707B2 (xx)
BR (1) BR9301436A (xx)
CA (1) CA2093305A1 (xx)
CZ (1) CZ285698B6 (xx)
DE (1) DE59309726D1 (xx)
DK (1) DK0564972T3 (xx)
ES (1) ES2136626T3 (xx)
FI (1) FI931474A (xx)
GR (1) GR3031543T3 (xx)
HU (1) HU217613B (xx)
IL (1) IL105287A (xx)
MX (1) MX9301926A (xx)
NO (1) NO311941B1 (xx)
NZ (1) NZ247317A (xx)
PL (1) PL175901B1 (xx)
RU (1) RU2109747C1 (xx)
SK (1) SK281970B6 (xx)
TW (1) TW258739B (xx)
ZA (1) ZA932399B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE280777T1 (de) * 1994-03-09 2004-11-15 Cortech Inc Bradykinin-antagonist peptide mit n- substituierten glycinen
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
FR2790260B1 (fr) 1999-02-26 2001-05-04 Fournier Ind & Sante Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique
US6699486B1 (en) 1999-11-18 2004-03-02 Bolla Corporation Treatment or prevention of photoaging and skin cancer
US7105172B1 (en) 1999-11-18 2006-09-12 Bolla John D Treatment of rosacea
US20040248809A1 (en) * 2003-02-07 2004-12-09 Aventis Pharma Deutschland Gmbh Use of antagonists of the bradykinin B2 receptor for the treatment of osteoarthrosis
EP3781586B1 (en) 2018-04-20 2024-04-17 Fresenius Kabi iPSUM S.r.l. A method for production of high purity icatibant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210584A (en) * 1979-01-15 1980-07-01 Eli Lilly And Company Vindesine synthesis
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE69012142D1 (de) * 1989-12-08 1994-10-06 Univ Boston Acylierte bradykininantagonisten und deren verwendung.
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina

Also Published As

Publication number Publication date
CN1040330C (zh) 1998-10-21
IL105287A (en) 1999-12-31
AU3565193A (en) 1993-10-07
IL105287A0 (en) 1993-08-18
CN1077202A (zh) 1993-10-13
ATE183197T1 (de) 1999-08-15
ES2136626T3 (es) 1999-12-01
PL298362A1 (en) 1993-10-18
FI931474A0 (fi) 1993-04-01
NO931287L (no) 1993-10-05
KR930021656A (ko) 1993-11-22
NZ247317A (en) 1995-03-28
DE59309726D1 (de) 1999-09-16
FI931474A (fi) 1993-10-05
SK281970B6 (sk) 2001-09-11
GR3031543T3 (en) 2000-01-31
HU9300972D0 (en) 1993-06-28
RU2109747C1 (ru) 1998-04-27
EP0564972A3 (en) 1994-10-05
JP3426639B2 (ja) 2003-07-14
SK28993A3 (en) 1993-11-10
EP0564972A2 (de) 1993-10-13
JPH0665289A (ja) 1994-03-08
KR100273825B1 (ko) 2000-12-15
TW258739B (xx) 1995-10-01
CA2093305A1 (en) 1993-10-05
MX9301926A (es) 1993-10-01
AU667707B2 (en) 1996-04-04
HU217613B (hu) 2000-03-28
NO931287D0 (no) 1993-04-02
NO311941B1 (no) 2002-02-18
PL175901B1 (pl) 1999-03-31
CZ57293A3 (en) 1994-03-16
EP0564972B1 (de) 1999-08-11
HUT64775A (en) 1994-02-28
BR9301436A (pt) 1993-10-13
US5597803A (en) 1997-01-28
CZ285698B6 (cs) 1999-10-13
DK0564972T3 (da) 2000-01-24

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