ZA913779B - Method for synthesis - Google Patents

Method for synthesis

Info

Publication number
ZA913779B
ZA913779B ZA913779A ZA913779A ZA913779B ZA 913779 B ZA913779 B ZA 913779B ZA 913779 A ZA913779 A ZA 913779A ZA 913779 A ZA913779 A ZA 913779A ZA 913779 B ZA913779 B ZA 913779B
Authority
ZA
South Africa
Prior art keywords
synthesis
Prior art date
Application number
ZA913779A
Other languages
English (en)
Inventor
Arne Elof Braendstroem
Elof Braendstroem Arne
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA913779B publication Critical patent/ZA913779B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
ZA913779A 1990-06-07 1991-05-17 Method for synthesis ZA913779B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002043A SE9002043D0 (sv) 1990-06-07 1990-06-07 Improved method for synthesis

Publications (1)

Publication Number Publication Date
ZA913779B true ZA913779B (en) 1992-02-26

Family

ID=20379708

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA913779A ZA913779B (en) 1990-06-07 1991-05-17 Method for synthesis

Country Status (42)

Country Link
US (1) US5386032A (xx)
EP (1) EP0533752B1 (xx)
JP (1) JP2993122B2 (xx)
KR (1) KR0178045B1 (xx)
CN (1) CN1040536C (xx)
AP (1) AP216A (xx)
AT (1) ATE162790T1 (xx)
AU (1) AU640246B2 (xx)
BG (1) BG61265B1 (xx)
CA (1) CA2083605C (xx)
CZ (1) CZ279928B6 (xx)
DE (1) DE69128832T2 (xx)
DK (1) DK0533752T3 (xx)
DZ (1) DZ1504A1 (xx)
EG (1) EG19392A (xx)
ES (1) ES2113378T3 (xx)
FI (1) FI102967B (xx)
GR (1) GR3026642T3 (xx)
HK (1) HK1003831A1 (xx)
HR (1) HRP920770B1 (xx)
HU (1) HU214323B (xx)
IE (1) IE911845A1 (xx)
IL (1) IL98274A (xx)
IS (1) IS1752B (xx)
LT (1) LT3584B (xx)
LV (1) LV10271B (xx)
MA (1) MA22171A1 (xx)
NO (1) NO300541B1 (xx)
NZ (1) NZ238224A (xx)
PL (1) PL165433B1 (xx)
PT (1) PT97873B (xx)
RO (1) RO111366B1 (xx)
RU (1) RU2061693C1 (xx)
SA (1) SA91120027B1 (xx)
SE (1) SE9002043D0 (xx)
SG (1) SG48053A1 (xx)
SK (1) SK278505B6 (xx)
TN (1) TNSN91042A1 (xx)
UA (1) UA32524C2 (xx)
WO (1) WO1991018895A1 (xx)
YU (1) YU47570B (xx)
ZA (1) ZA913779B (xx)

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SE521100C2 (sv) * 1995-12-15 2003-09-30 Astra Ab Förfarande för framställning av en bensimidazolförening
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SK283805B6 (sk) 1996-09-09 2004-02-03 Slovakofarma, A. S. Spôsob prípravy omeprazolu
US6437139B1 (en) 1997-05-06 2002-08-20 Pdi-Research Laboratories, Inc. Synthesis of pharmaceutically useful pyridine derivatives
CA2204580A1 (en) * 1997-05-06 1998-11-06 Michel Zoghbi Synthesis of pharmaceutically useful pyridine derivatives
KR100463031B1 (ko) * 1997-05-26 2005-04-06 동아제약주식회사 5-메톡시-2-[3,5-디메틸-4-메톡시피리딜메틸)설피닐]-1h-벤즈이미다졸의신규제조방법
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
SE9704183D0 (sv) 1997-11-14 1997-11-14 Astra Ab New process
SI20019A (sl) * 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
US6191148B1 (en) 1998-08-11 2001-02-20 Merck & Co., Inc. Omerazole process and compositions thereof
US6166213A (en) * 1998-08-11 2000-12-26 Merck & Co., Inc. Omeprazole process and compositions thereof
US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
UA72748C2 (en) * 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
US6353005B1 (en) 1999-03-02 2002-03-05 Sepracor, Inc. Method and compositions using (+) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
US6362202B1 (en) 1999-03-02 2002-03-26 Sepracor Inc. Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
DE19951960C2 (de) * 1999-10-28 2002-06-27 Gruenenthal Gmbh Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
ES2209678T1 (es) * 2001-02-02 2004-07-01 Teva Pharmaceutical Industries Ltd. Procedimientos para proporcionar 2-(2-piridilmetil)sulfonil-1h-benzimidazoles sustituidos.
KR100783020B1 (ko) * 2001-03-23 2007-12-07 동아제약주식회사 2-메틸클로라이드 피리딘 유도체 및 이를 이용한 벤즈이미다졸 유도체의 제조 방법
ES2261703T3 (es) * 2001-07-16 2006-11-16 Janssen Pharmaceutica N.V. Proceso mejorado para preparar compuestos de tipo bencimidazol.
EP1469839A2 (en) * 2002-01-25 2004-10-27 Santarus, Inc. Transmucosal delivery of proton pump inhibitors
SE0203092D0 (en) 2002-10-18 2002-10-18 Astrazeneca Ab Method for the synthesis of a benzimidazole compound
TWI367759B (en) * 2003-02-20 2012-07-11 Santarus Inc A novel formulation, omeprazole antacid complex-immediate release, for rapid and sustained suppression of gastric acid
TWI398273B (zh) * 2003-07-18 2013-06-11 Santarus Inc 用於抑制酸分泌之醫藥調配物及其製備及使用之方法
EP1648417A4 (en) * 2003-07-18 2010-01-20 Santarus Inc PHARMACEUTICAL FORMULATION AND METHOD FOR THE TREATMENT OF GASTROINTESTINAL ACIDITY RELATED DISORDERS
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2579665C (en) 2004-09-13 2014-03-18 Takeda Pharmaceutical Company Limited Method and apparatus for producing oxidized compound
PL1802584T3 (pl) * 2004-10-11 2010-03-31 Ranbaxy Laboratories Ltd Sposób wytwarzania podstawionych sulfotlenków
KR100641534B1 (ko) 2005-07-28 2006-11-01 한미약품 주식회사 에스오메프라졸 및 그의 염의 제조방법
EP1954669B1 (en) 2005-12-01 2015-07-08 Auspex Pharmaceuticals, Inc. Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
WO2007129328A2 (en) * 2006-05-09 2007-11-15 Cadila Healthcare Limited Process for preparing 2-[pyridinyl]sulfinyl-substituted benzimidazoles
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
EP2114919A2 (en) 2007-01-31 2009-11-11 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically pure omeprazole via salt formation with a chiral amine or treatment with an entiomer converting enzyme and chromatographic seperation
PT2125698T (pt) 2007-03-15 2016-12-12 Auspex Pharmaceuticals Inc D9-venlafaxina deuterada
GB2471619B (en) * 2008-03-31 2012-10-31 Council Scient Ind Res Method for the simultaneous preparation of 3-acetoxy-17-acetamdo-16-formyl-androst-5,16-diene and 3-acetoxy-2'-chloro-5-androsteno[17,6-B]pyridine
WO2010134099A1 (en) 2009-05-21 2010-11-25 Cadila Healthcare Limited One pot process for preparing omeprazole and related compounds
CN102786513A (zh) * 2011-05-18 2012-11-21 中国医学科学院药物研究所 奥美拉唑晶e型物质及制备方法与在药品和保健品中应用
CN104203938A (zh) 2012-01-21 2014-12-10 朱比兰特生命科学有限公司 用于制备2-吡啶基甲基亚硫酰基苯并咪唑、它们的类似物和光学活性对映体的方法
EP4034143A1 (en) 2019-09-24 2022-08-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN148930B (xx) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4307102A (en) * 1981-02-19 1981-12-22 Sterling Drug Inc. Phenanthro[2,3-c]pyrazole
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
ZW4585A1 (en) * 1984-04-19 1985-11-20 Hoffmann La Roche Imidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8500996D0 (sv) * 1985-03-01 1985-03-01 Haessle Ab Method of treatment
SE8600658D0 (sv) * 1986-02-14 1986-02-14 Haessle Ab Novel composition of matter
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
SE9002206D0 (sv) * 1990-06-20 1990-06-20 Haessle Ab New compounds
NZ244301A (en) * 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds

Also Published As

Publication number Publication date
AP216A (en) 1992-09-02
LTIP1711A (en) 1995-07-25
NO300541B1 (no) 1997-06-16
NO924682L (no) 1992-12-04
HUT63408A (en) 1993-08-30
SE9002043D0 (sv) 1990-06-07
FI925529A0 (fi) 1992-12-04
DE69128832D1 (de) 1998-03-05
PL165433B1 (pl) 1994-12-30
SG48053A1 (en) 1998-04-17
AP9100274A0 (en) 1991-07-31
IS3711A7 (is) 1991-12-08
LV10271B (en) 1995-04-20
RU2061693C1 (ru) 1996-06-10
IL98274A (en) 1995-03-30
MA22171A1 (fr) 1991-12-31
ATE162790T1 (de) 1998-02-15
NO924682D0 (no) 1992-12-04
FI925529A (fi) 1992-12-04
DK0533752T3 (da) 1998-06-02
JP2993122B2 (ja) 1999-12-20
CN1040536C (zh) 1998-11-04
LV10271A (lv) 1994-10-20
PT97873A (pt) 1992-04-30
JPH05507699A (ja) 1993-11-04
SA91120027B1 (ar) 2002-06-03
ES2113378T3 (es) 1998-05-01
HK1003831A1 (en) 1998-11-06
TNSN91042A1 (fr) 1992-10-25
EG19392A (en) 1995-06-29
IL98274A0 (en) 1992-06-21
DE69128832T2 (de) 1998-05-28
YU47570B (sh) 1995-10-03
EP0533752A1 (en) 1993-03-31
CS172691A3 (en) 1992-01-15
WO1991018895A1 (en) 1991-12-12
FI102967B1 (fi) 1999-03-31
PT97873B (pt) 1998-10-30
YU99291A (sh) 1993-11-16
HU9203855D0 (en) 1993-03-29
IE911845A1 (en) 1991-12-18
IS1752B (is) 2000-07-21
CA2083605A1 (en) 1991-12-08
NZ238224A (en) 1993-11-25
RO111366B1 (ro) 1996-09-30
BG61265B1 (en) 1997-04-30
HRP920770B1 (en) 2000-06-30
CN1058211A (zh) 1992-01-29
FI102967B (fi) 1999-03-31
HU214323B (hu) 1998-03-02
CZ279928B6 (cs) 1995-08-16
UA32524C2 (uk) 2001-02-15
DZ1504A1 (fr) 2004-09-13
AU640246B2 (en) 1993-08-19
GR3026642T3 (en) 1998-07-31
KR0178045B1 (en) 1999-03-20
HRP920770A2 (en) 1995-12-31
LT3584B (en) 1995-12-27
EP0533752B1 (en) 1998-01-28
CA2083605C (en) 1998-12-08
AU8080791A (en) 1991-12-31
US5386032A (en) 1995-01-31
SK278505B6 (en) 1997-08-06
BG97146A (bg) 1993-12-24

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