ZA91376B - Process for the preparation of medications in the form of prills - Google Patents

Process for the preparation of medications in the form of prills

Info

Publication number
ZA91376B
ZA91376B ZA91376A ZA91376A ZA91376B ZA 91376 B ZA91376 B ZA 91376B ZA 91376 A ZA91376 A ZA 91376A ZA 91376 A ZA91376 A ZA 91376A ZA 91376 B ZA91376 B ZA 91376B
Authority
ZA
South Africa
Prior art keywords
active substance
preparation
pearls
prills
medications
Prior art date
Application number
ZA91376A
Other languages
English (en)
Inventor
Michel Deleuil
Deleuil Michel
Pierre Labourt-Ibarre
Labourt-Ibarre Pierre
Robert Rona
Rona Robert
Eraclis Statiotis
Statiotis Eraclis
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA91376B publication Critical patent/ZA91376B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Measurement Of Force In General (AREA)
  • Keying Circuit Devices (AREA)
  • Air Bags (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
ZA91376A 1990-01-19 1991-01-18 Process for the preparation of medications in the form of prills ZA91376B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909000623A FR2657257B1 (fr) 1990-01-19 1990-01-19 Procede de preparation de medicaments sous forme de perles.

Publications (1)

Publication Number Publication Date
ZA91376B true ZA91376B (en) 1991-11-27

Family

ID=9392948

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA91376A ZA91376B (en) 1990-01-19 1991-01-18 Process for the preparation of medications in the form of prills

Country Status (29)

Country Link
US (2) US5188838A (lv)
EP (1) EP0438359B1 (lv)
JP (1) JP3310305B2 (lv)
KR (1) KR0163050B1 (lv)
CN (1) CN1054189A (lv)
AT (1) ATE103489T1 (lv)
AU (1) AU651566B2 (lv)
BG (1) BG60899B1 (lv)
CA (1) CA2034413A1 (lv)
CZ (1) CZ279869B6 (lv)
DE (1) DE69101493T2 (lv)
DK (1) DK0438359T3 (lv)
ES (1) ES2062700T3 (lv)
FI (1) FI102590B1 (lv)
FR (1) FR2657257B1 (lv)
HU (1) HU211076B (lv)
IE (1) IE65102B1 (lv)
IL (1) IL96984A (lv)
LV (1) LV10039B (lv)
NO (1) NO180516C (lv)
NZ (1) NZ236820A (lv)
PL (1) PL165719B1 (lv)
PT (1) PT96526B (lv)
RO (1) RO108646B1 (lv)
RU (1) RU1837872C (lv)
SK (1) SK278757B6 (lv)
TW (1) TW327131B (lv)
YU (1) YU7691A (lv)
ZA (1) ZA91376B (lv)

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DE4131562A1 (de) * 1991-09-18 1993-03-25 Medac Klinische Spezialpraep Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln)
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DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
FR2702968B1 (fr) * 1993-03-23 1995-06-23 Lafon Labor Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation .
US5843347A (en) * 1993-03-23 1998-12-01 Laboratoire L. Lafon Extrusion and freeze-drying method for preparing particles containing an active ingredient
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
EP0706374B1 (en) * 1993-06-30 1997-12-10 Genentech, Inc. Method for preparing liposomes
FR2707184B1 (fr) * 1993-07-08 1995-08-11 Rhone Poulenc Nutrition Animal Procédé de préparation de sphérules contenant un principe actif alimentaire ou pharmaceutique.
FR2710500B1 (fr) * 1993-09-27 1995-12-01 Virbac Laboratoires Composition et système à administration orale pour animaux, leur procédé de préparation et leurs applications.
ES2199981T3 (es) * 1994-02-16 2004-03-01 Abbott Laboratories Modo de preparacion de formulaciones farmaceuticas de particulas finas.
FR2720631B1 (fr) * 1994-06-03 1996-07-12 Rhone Poulenc Rorer Sa Procédé de préparation et perles obtenues contenant un principe actif présentant un point de fusion non défini.
IT1274879B (it) * 1994-08-03 1997-07-25 Saitec Srl Apparecchio e metodo per preparare forme farmaceutiche solide a rilascio controllato del principio attivo.
FR2732621B1 (fr) * 1995-04-10 1997-06-06 Rhone Poulenc Chimie Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention
FR2754177B1 (fr) * 1996-10-07 1999-08-06 Sanofi Sa Microspheres pharmaceutiques d'acide valproique pour administration orale
US6171615B1 (en) 1998-07-06 2001-01-09 Gattefoss{acute over (e)} Sustained release theophylline formulations, excipient systems and methods of production
DE19845126A1 (de) * 1998-09-30 2000-04-06 Marco Systemanalyse Entw Verfahren zur Tropfenbildung
DE19848849A1 (de) * 1998-10-22 2000-04-27 Knoll Ag Verfahren zur Herstellung von festen, sphärischen Formen, enthaltend eine biologisch aktive Substanz
EP1187601B1 (en) * 1999-06-07 2005-07-27 ALTANA Pharma AG Novel preparation and administration form comprising an acid-labile proton pump inhibitor
DE19952790A1 (de) * 1999-11-03 2001-05-17 Cognis Deutschland Gmbh Verfahren zur Herstellung von Fettstoffgranulaten
DE10009996B4 (de) * 2000-03-02 2005-10-13 Cognis Ip Management Gmbh Feststoffgranulate mit monodisperser Korngrößenverteilung, ein Verfahren zu ihrer Herstellung sowie ihre Verwendung
FR2806307B1 (fr) * 2000-03-20 2002-11-15 Mane Fils V Preparation parfumee solide sous forme de microbilles et utilisation de ladite preparation
DE10019508A1 (de) * 2000-04-19 2001-10-31 Rieter Automatik Gmbh Verfahren und Vorrichtung zur Vertropfung von Vorprodukten thermoplastischer Polyester oder Copolyester
DE10022810A1 (de) * 2000-05-10 2001-11-22 Cognis Deutschland Gmbh Granulierte Kunststoffhilfsmittel mit monodisperser Korngrößenverteilung
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
DE10124916A1 (de) * 2001-05-22 2002-11-28 Cognis Deutschland Gmbh Kugelförmige Lackadditive, deren Herstellung und Verwendung
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
RU2005108609A (ru) * 2002-09-28 2006-03-10 МакНЕЙЛ-ППС, ИНК. (US) Лекарственные формы с модифицированным высвобождением, имеющие два ядра и отверстие
US20040146553A1 (en) * 2002-12-23 2004-07-29 Aventis Pharma S.A. Compositions for oral administration of active principles requiring masking of taste
FR2848855B1 (fr) * 2002-12-23 2005-02-11 Aventis Pharma Sa Compositions pour administration orale de principes actifs necessitant un masquage du gout
RS20050669A (en) 2003-03-10 2008-04-04 Altana Pharma Ag., Novel process for the preparation of roflumilast
DK1861074T3 (da) * 2005-03-16 2013-07-29 Takeda Gmbh Smagsmaskeret doseringsform indeholdende roflumilast
KR100902781B1 (ko) * 2007-10-05 2009-06-12 (주)라이프코드 일체형 무균 캡슐 제조장치
CN101279220B (zh) * 2007-12-28 2011-06-08 天津天士力制药股份有限公司 利用冷却空气制备滴丸的方法及使用其方法的设备
KR101802553B1 (ko) * 2010-09-23 2017-11-28 모노졸 알엑스, 엘엘씨 제약 생성물을 패키지 표면 상에 직접적으로 형성시키는 방법 및 시스템
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US9545376B2 (en) 2013-01-23 2017-01-17 Arx, Llc Production of unit dose constructs
JP5959556B2 (ja) 2014-03-12 2016-08-02 三菱電機株式会社 エンジン始動装置
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
EP3452023A1 (en) 2016-05-05 2019-03-13 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions

Family Cites Families (13)

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FR1302362A (fr) * 1959-10-23 1962-08-31 Olin Mathieson Procédé pour la préparation de pilules à libération temporisée
DE2416904A1 (de) * 1974-04-06 1975-10-16 Bayer Ag Verfahren zur herstellung kugelfoermigen phenacetingranulates und vorrichtung zur durchfuehrung des verfahrens
US4035116A (en) * 1976-09-10 1977-07-12 Arthur D. Little, Inc. Process and apparatus for forming essentially spherical pellets directly from a melt
DE2725849C3 (de) * 1977-06-08 1980-11-13 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Vorrichtung zur Herstellung von kugelförmigen Teilchen
DE2725924C3 (de) * 1977-06-08 1980-11-06 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Verfahren zur Herstellung kugelförmiger Teilchen aus niedrigschmelzenden organischen Substanzen
FR2433949A1 (fr) * 1978-08-25 1980-03-21 Commissariat Energie Atomique Substrat hydrophobe apte a liberer une substance chimique
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
US4313745A (en) * 1980-12-24 1982-02-02 Lovelace Alan M Method of forming frozen spheres in a force-free drop tower
US4525198A (en) * 1981-05-13 1985-06-25 Compagnie Neerlandaise De L'azote Process for the production of urea granules
CA1154213A (en) * 1981-07-07 1983-09-27 John T. Higgins Sulfur prilling
ATE12224T1 (de) * 1981-11-17 1985-04-15 Kabivitrum Ab Verbindungen mit antifibrinolytischer wirksamkeit.
DE3345983C2 (de) * 1983-12-20 1986-09-04 Wolfgang 4600 Dortmund Seidler Verfahren und Vorrichtung zur Herstellung von kugelförmigen metallischen Partikeln
EP0209403B1 (en) * 1985-07-15 1991-10-23 Research Development Corporation of Japan Process for preparing ultrafine particles of organic compounds

Also Published As

Publication number Publication date
IL96984A0 (en) 1992-03-29
DK0438359T3 (da) 1994-05-02
CS9100105A2 (en) 1991-08-13
FI910273A0 (fi) 1991-01-18
US5188838A (en) 1993-02-23
CN1054189A (zh) 1991-09-04
ATE103489T1 (de) 1994-04-15
TW327131B (en) 1998-02-21
LV10039B (en) 1995-02-20
NO180516C (no) 1997-05-07
EP0438359B1 (fr) 1994-03-30
EP0438359A1 (fr) 1991-07-24
NO180516B (no) 1997-01-27
AU6948191A (en) 1991-07-25
JP3310305B2 (ja) 2002-08-05
PT96526A (pt) 1991-10-15
PL165719B1 (pl) 1995-01-31
HU910178D0 (en) 1991-08-28
PT96526B (pt) 1998-06-30
DE69101493D1 (de) 1994-05-05
LV10039A (lv) 1994-05-10
FI102590B (fi) 1999-01-15
HU211076B (en) 1995-10-30
SK278757B6 (sk) 1998-02-04
RU1837872C (ru) 1993-08-30
BG60899B1 (bg) 1996-06-28
KR0163050B1 (ko) 1998-12-01
FR2657257B1 (fr) 1994-09-02
CA2034413A1 (fr) 1991-07-20
NZ236820A (en) 1991-11-26
JPH04212359A (ja) 1992-08-03
ES2062700T3 (es) 1994-12-16
YU7691A (sh) 1994-04-05
US5380532A (en) 1995-01-10
AU651566B2 (en) 1994-07-28
IL96984A (en) 1996-03-31
FR2657257A1 (fr) 1991-07-26
CZ279869B6 (cs) 1995-07-12
DE69101493T2 (de) 1994-08-04
KR910014114A (ko) 1991-08-31
FI102590B1 (fi) 1999-01-15
RO108646B1 (ro) 1994-07-29
FI910273A (fi) 1991-07-20
BG93649A (bg) 1993-12-24
IE65102B1 (en) 1995-10-04
NO910218L (no) 1991-07-22
IE910176A1 (en) 1991-07-31
NO910218D0 (no) 1991-01-18

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