FI910273A - Foerfarande foer framstaellning av paerlformade laekemedel. - Google Patents

Foerfarande foer framstaellning av paerlformade laekemedel. Download PDF

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Publication number
FI910273A
FI910273A FI910273A FI910273A FI910273A FI 910273 A FI910273 A FI 910273A FI 910273 A FI910273 A FI 910273A FI 910273 A FI910273 A FI 910273A FI 910273 A FI910273 A FI 910273A
Authority
FI
Finland
Prior art keywords
paerlformade
ceekemedel
active substance
foerfarande foer
foer framstaellning
Prior art date
Application number
FI910273A
Other languages
English (en)
Other versions
FI102590B1 (fi
FI910273A0 (fi
FI102590B (fi
Inventor
Michel Deleuil
Pierre Labourt-Ibarre
Robert Rona
Eraclis Statiotis
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of FI910273A0 publication Critical patent/FI910273A0/fi
Publication of FI910273A publication Critical patent/FI910273A/fi
Application granted granted Critical
Publication of FI102590B1 publication Critical patent/FI102590B1/fi
Publication of FI102590B publication Critical patent/FI102590B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Keying Circuit Devices (AREA)
  • Air Bags (AREA)
  • Measurement Of Force In General (AREA)
  • Steroid Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI910273A 1990-01-19 1991-01-18 Menetelmä helmen muotoisten lääkkeiden valmistamiseksi FI102590B (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909000623A FR2657257B1 (fr) 1990-01-19 1990-01-19 Procede de preparation de medicaments sous forme de perles.

Publications (4)

Publication Number Publication Date
FI910273A0 FI910273A0 (fi) 1991-01-18
FI910273A true FI910273A (fi) 1991-07-20
FI102590B1 FI102590B1 (fi) 1999-01-15
FI102590B FI102590B (fi) 1999-01-15

Family

ID=9392948

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910273A FI102590B (fi) 1990-01-19 1991-01-18 Menetelmä helmen muotoisten lääkkeiden valmistamiseksi

Country Status (29)

Country Link
US (2) US5188838A (fi)
EP (1) EP0438359B1 (fi)
JP (1) JP3310305B2 (fi)
KR (1) KR0163050B1 (fi)
CN (1) CN1054189A (fi)
AT (1) ATE103489T1 (fi)
AU (1) AU651566B2 (fi)
BG (1) BG60899B1 (fi)
CA (1) CA2034413A1 (fi)
CZ (1) CZ279869B6 (fi)
DE (1) DE69101493T2 (fi)
DK (1) DK0438359T3 (fi)
ES (1) ES2062700T3 (fi)
FI (1) FI102590B (fi)
FR (1) FR2657257B1 (fi)
HU (1) HU211076B (fi)
IE (1) IE65102B1 (fi)
IL (1) IL96984A (fi)
LV (1) LV10039B (fi)
NO (1) NO180516C (fi)
NZ (1) NZ236820A (fi)
PL (1) PL165719B1 (fi)
PT (1) PT96526B (fi)
RO (1) RO108646B1 (fi)
RU (1) RU1837872C (fi)
SK (1) SK278757B6 (fi)
TW (1) TW327131B (fi)
YU (1) YU7691A (fi)
ZA (1) ZA91376B (fi)

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DE4131562A1 (de) * 1991-09-18 1993-03-25 Medac Klinische Spezialpraep Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln)
HUT75616A (en) * 1992-03-17 1997-05-28 Pfizer Method for prooucing porous delivery devices
DE4244466C2 (de) * 1992-12-24 1995-02-23 Pharmatech Gmbh Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
US5843347A (en) * 1993-03-23 1998-12-01 Laboratoire L. Lafon Extrusion and freeze-drying method for preparing particles containing an active ingredient
FR2702968B1 (fr) * 1993-03-23 1995-06-23 Lafon Labor Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation .
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
DE69407292T2 (de) * 1993-06-30 1998-06-25 Genentech Inc Verfahren zur herstellung von liposomen
FR2707184B1 (fr) * 1993-07-08 1995-08-11 Rhone Poulenc Nutrition Animal Procédé de préparation de sphérules contenant un principe actif alimentaire ou pharmaceutique.
FR2710500B1 (fr) * 1993-09-27 1995-12-01 Virbac Laboratoires Composition et système à administration orale pour animaux, leur procédé de préparation et leurs applications.
PT744941E (pt) * 1994-02-16 2003-10-31 Abbott Lab Processo para preparar formulacoes farmaceuticas de particulas finas
FR2720631B1 (fr) * 1994-06-03 1996-07-12 Rhone Poulenc Rorer Sa Procédé de préparation et perles obtenues contenant un principe actif présentant un point de fusion non défini.
IT1274879B (it) * 1994-08-03 1997-07-25 Saitec Srl Apparecchio e metodo per preparare forme farmaceutiche solide a rilascio controllato del principio attivo.
FR2732621B1 (fr) * 1995-04-10 1997-06-06 Rhone Poulenc Chimie Perles d'un produit presentant le phenomene de surfusion et leur procede d'obtention
FR2754177B1 (fr) * 1996-10-07 1999-08-06 Sanofi Sa Microspheres pharmaceutiques d'acide valproique pour administration orale
US6171615B1 (en) 1998-07-06 2001-01-09 Gattefoss{acute over (e)} Sustained release theophylline formulations, excipient systems and methods of production
DE19845126A1 (de) * 1998-09-30 2000-04-06 Marco Systemanalyse Entw Verfahren zur Tropfenbildung
DE19848849A1 (de) * 1998-10-22 2000-04-27 Knoll Ag Verfahren zur Herstellung von festen, sphärischen Formen, enthaltend eine biologisch aktive Substanz
ATE300285T1 (de) * 1999-06-07 2005-08-15 Altana Pharma Ag Neue zubereitung und darreichungsform enthaltend einen säurelabilen protonenpumpeninhibitor
DE19952790A1 (de) * 1999-11-03 2001-05-17 Cognis Deutschland Gmbh Verfahren zur Herstellung von Fettstoffgranulaten
DE10009996B4 (de) * 2000-03-02 2005-10-13 Cognis Ip Management Gmbh Feststoffgranulate mit monodisperser Korngrößenverteilung, ein Verfahren zu ihrer Herstellung sowie ihre Verwendung
FR2806307B1 (fr) * 2000-03-20 2002-11-15 Mane Fils V Preparation parfumee solide sous forme de microbilles et utilisation de ladite preparation
DE10019508A1 (de) * 2000-04-19 2001-10-31 Rieter Automatik Gmbh Verfahren und Vorrichtung zur Vertropfung von Vorprodukten thermoplastischer Polyester oder Copolyester
DE10022810A1 (de) * 2000-05-10 2001-11-22 Cognis Deutschland Gmbh Granulierte Kunststoffhilfsmittel mit monodisperser Korngrößenverteilung
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
DE10124916A1 (de) * 2001-05-22 2002-11-28 Cognis Deutschland Gmbh Kugelförmige Lackadditive, deren Herstellung und Verwendung
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
RU2005108609A (ru) * 2002-09-28 2006-03-10 МакНЕЙЛ-ППС, ИНК. (US) Лекарственные формы с модифицированным высвобождением, имеющие два ядра и отверстие
FR2848855B1 (fr) * 2002-12-23 2005-02-11 Aventis Pharma Sa Compositions pour administration orale de principes actifs necessitant un masquage du gout
US20040146553A1 (en) 2002-12-23 2004-07-29 Aventis Pharma S.A. Compositions for oral administration of active principles requiring masking of taste
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
WO2006097456A1 (en) 2005-03-16 2006-09-21 Nycomed Gmbh Taste masked dosage form containing roflumilast
KR100902781B1 (ko) * 2007-10-05 2009-06-12 (주)라이프코드 일체형 무균 캡슐 제조장치
CN101279220B (zh) * 2007-12-28 2011-06-08 天津天士力制药股份有限公司 利用冷却空气制备滴丸的方法及使用其方法的设备
EP2618822B1 (en) * 2010-09-23 2020-02-26 Aquestive Therapeutics, Inc. Method and system for forming a pharmaceutical product directly onto a packaging surface
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US9545376B2 (en) 2013-01-23 2017-01-17 Arx, Llc Production of unit dose constructs
JP5959556B2 (ja) 2014-03-12 2016-08-02 三菱電機株式会社 エンジン始動装置
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
CA3022840A1 (en) 2016-05-05 2017-11-09 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions

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FR1302362A (fr) * 1959-10-23 1962-08-31 Olin Mathieson Procédé pour la préparation de pilules à libération temporisée
DE2416904A1 (de) * 1974-04-06 1975-10-16 Bayer Ag Verfahren zur herstellung kugelfoermigen phenacetingranulates und vorrichtung zur durchfuehrung des verfahrens
US4035116A (en) * 1976-09-10 1977-07-12 Arthur D. Little, Inc. Process and apparatus for forming essentially spherical pellets directly from a melt
DE2725849C3 (de) * 1977-06-08 1980-11-13 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Vorrichtung zur Herstellung von kugelförmigen Teilchen
DE2725924C3 (de) * 1977-06-08 1980-11-06 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Verfahren zur Herstellung kugelförmiger Teilchen aus niedrigschmelzenden organischen Substanzen
FR2433949A1 (fr) * 1978-08-25 1980-03-21 Commissariat Energie Atomique Substrat hydrophobe apte a liberer une substance chimique
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
US4313745A (en) * 1980-12-24 1982-02-02 Lovelace Alan M Method of forming frozen spheres in a force-free drop tower
US4525198A (en) * 1981-05-13 1985-06-25 Compagnie Neerlandaise De L'azote Process for the production of urea granules
CA1154213A (en) * 1981-07-07 1983-09-27 John T. Higgins Sulfur prilling
DE3262698D1 (en) * 1981-11-17 1985-04-25 Kabivitrum Ab Antifibrinolytically active compounds
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Also Published As

Publication number Publication date
KR910014114A (ko) 1991-08-31
YU7691A (sh) 1994-04-05
CS9100105A2 (en) 1991-08-13
NO180516B (no) 1997-01-27
NO180516C (no) 1997-05-07
IL96984A0 (en) 1992-03-29
CZ279869B6 (cs) 1995-07-12
FI102590B1 (fi) 1999-01-15
IE65102B1 (en) 1995-10-04
EP0438359B1 (fr) 1994-03-30
DK0438359T3 (da) 1994-05-02
IE910176A1 (en) 1991-07-31
US5188838A (en) 1993-02-23
NZ236820A (en) 1991-11-26
HU211076B (en) 1995-10-30
PL165719B1 (pl) 1995-01-31
BG93649A (bg) 1993-12-24
FI910273A0 (fi) 1991-01-18
TW327131B (en) 1998-02-21
PT96526B (pt) 1998-06-30
AU651566B2 (en) 1994-07-28
KR0163050B1 (ko) 1998-12-01
JPH04212359A (ja) 1992-08-03
CN1054189A (zh) 1991-09-04
IL96984A (en) 1996-03-31
FR2657257A1 (fr) 1991-07-26
ATE103489T1 (de) 1994-04-15
SK278757B6 (sk) 1998-02-04
AU6948191A (en) 1991-07-25
RU1837872C (ru) 1993-08-30
LV10039A (lv) 1994-05-10
DE69101493T2 (de) 1994-08-04
NO910218L (no) 1991-07-22
HU910178D0 (en) 1991-08-28
FR2657257B1 (fr) 1994-09-02
ZA91376B (en) 1991-11-27
BG60899B1 (bg) 1996-06-28
CA2034413A1 (fr) 1991-07-20
NO910218D0 (no) 1991-01-18
ES2062700T3 (es) 1994-12-16
PT96526A (pt) 1991-10-15
LV10039B (en) 1995-02-20
RO108646B1 (ro) 1994-07-29
DE69101493D1 (de) 1994-05-05
JP3310305B2 (ja) 2002-08-05
US5380532A (en) 1995-01-10
FI102590B (fi) 1999-01-15
EP0438359A1 (fr) 1991-07-24

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FG Patent granted

Owner name: RHONE-POULENC SANTE