ZA89894B - Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them - Google Patents

Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA89894B
ZA89894B ZA89894A ZA89894A ZA89894B ZA 89894 B ZA89894 B ZA 89894B ZA 89894 A ZA89894 A ZA 89894A ZA 89894 A ZA89894 A ZA 89894A ZA 89894 B ZA89894 B ZA 89894B
Authority
ZA
South Africa
Prior art keywords
perhydrocycloalka
imadazone
diones
preparation
pharmaceutical compositions
Prior art date
Application number
ZA89894A
Other languages
English (en)
Inventor
Mario Pinza
Pinza Mario
Carlo Farina
Farina Carlo
Alberto Cerri
Cerri Alberto
Maria Teresa Riccaboni
Teresa Riccaboni Maria
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of ZA89894B publication Critical patent/ZA89894B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA89894A 1988-02-08 1989-02-06 Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them ZA89894B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819336A IT1233860B (it) 1988-02-08 1988-02-08 Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa

Publications (1)

Publication Number Publication Date
ZA89894B true ZA89894B (en) 1991-10-30

Family

ID=11156852

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA89894A ZA89894B (en) 1988-02-08 1989-02-06 Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (2) US5053422A (xx)
EP (1) EP0335483A3 (xx)
JP (1) JPH01246281A (xx)
KR (1) KR890013013A (xx)
CN (1) CN1036204A (xx)
AU (2) AU616240B2 (xx)
BR (1) BR8900541A (xx)
CA (1) CA1324378C (xx)
DD (2) DD283393A5 (xx)
DK (1) DK55089A (xx)
FI (1) FI890438A (xx)
HU (2) HU204794B (xx)
IT (1) IT1233860B (xx)
NO (1) NO168424C (xx)
NZ (1) NZ227833A (xx)
PL (1) PL158198B1 (xx)
PT (1) PT89657B (xx)
RO (4) RO104070B1 (xx)
RU (1) RU1799383C (xx)
ZA (1) ZA89894B (xx)
ZW (1) ZW1489A1 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9123641D0 (en) * 1991-11-07 1992-01-02 Isf Spa Process
TW304167B (xx) * 1995-01-30 1997-05-01 Lilly Co Eli
PE17897A1 (es) * 1995-02-17 1997-06-12 Lilly Co Eli Formulacion transdermica en parche del 3-(4-butiltio)-1,2,5-tiadiazol-3-il)-1-azabiciclo (2,2,2) octano
IL118323A (en) * 1995-06-02 1999-11-30 Akzo Nobel Nv 3,8-Diamino-8- hydroxyimidazo (1,5-a) pyridine -1(5H)-one derived serine protease inhibitors and pharmaceutical compositions containing them
JP3905409B2 (ja) 2002-04-10 2007-04-18 タレックス光学工業株式会社 光学レンズ成型用ポリウレタン樹脂組成物および耐衝撃性合成樹脂レンズ
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
ITMI20070770A1 (it) 2007-04-16 2008-10-17 Brane Discovery S R L Impiego di dimiracetam nel trattamento del dolore cronico
US9593209B2 (en) 2009-10-22 2017-03-14 Dow Corning Corporation Process for preparing clustered functional polyorganosiloxanes, and methods for their use
WO2012013640A1 (en) 2010-07-26 2012-02-02 Neurotune Ag Process for the preparation of dimiracetam
US9862867B2 (en) 2013-02-11 2018-01-09 Dow Corning Corporation Alkoxy-functional organopolysiloxane resin and polymer and related methods for forming same
US9670392B2 (en) 2013-02-11 2017-06-06 Dow Corning Corporation Stable thermal radical curable silicone adhesive compositions
JP6426628B2 (ja) 2013-02-11 2018-11-21 ダウ シリコーンズ コーポレーション 官能基密集型ポリオルガノシロキサン及びシリコーン反応性希釈剤を含む硬化性シリコーン組成物
EP2953994B1 (en) 2013-02-11 2021-09-08 Dow Silicones Corporation Moisture-curable hot melt silicone adhesive compositions including an alkoxy-functional siloxane reactive resin
CN105102575B (zh) 2013-02-11 2017-06-20 道康宁公司 用于形成导热热自由基固化有机硅组合物的原位方法
JP6370812B2 (ja) 2013-02-11 2018-08-08 ダウ シリコーンズ コーポレーション クラスタ化官能性ポリオルガノシロキサン、これを生成するプロセス、及びこれを使用する方法
JP6531043B2 (ja) 2013-02-11 2019-06-12 ダウ シリコーンズ コーポレーション 熱伝導性の熱ラジカル硬化型シリコーン組成物を形成する方法
EP3196229B1 (en) 2015-11-05 2018-09-26 Dow Silicones Corporation Branched polyorganosiloxanes and related curable compositions, methods, uses and devices
JOP20190251A1 (ar) 2017-05-31 2019-10-21 Metys Pharmaceuticals AG تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334099A (en) * 1965-03-31 1967-08-01 Sandoz Ag Novel pyrrolo-diazepines, pyrrolo-imidazolidines, and pyrrolo-pyrimidines
CA1067079A (en) * 1976-07-22 1979-11-27 Yamanouchi Pharmaceutical Co. Nitrogen-containing heterobicyclic compounds
US4372966A (en) * 1980-09-15 1983-02-08 Warner-Lambert Company Use of dihydro-1H-pyrrolizine-3,5(2H,6H)-dione as a cognition activator
US4582838A (en) * 1984-08-24 1986-04-15 Warner-Lambert Company Derivatives of dihydro-1H-pyrrolo[1,2-c]imidazol-3,5-dione as cognition activators
US4677098A (en) * 1985-11-22 1987-06-30 Warner-Lambert Company Substituted dihydro-1H-pyrolizine-3,5(2H,6H)-diones
JPS62289581A (ja) * 1986-06-09 1987-12-16 Idemitsu Kosan Co Ltd イミダゾピロリンジオン誘導体，その製造方法およびそれを有効成分とする除草剤
JPS62292783A (ja) * 1986-06-12 1987-12-19 Idemitsu Kosan Co Ltd イミダゾピロリンジオン誘導体，その製造方法およびそれを有効成分として含有する除草剤

Also Published As

Publication number Publication date
US5130319A (en) 1992-07-14
RO105963B1 (ro) 1993-01-30
RO105965B1 (ro) 1993-01-30
IT8819336A0 (it) 1988-02-08
NO890515D0 (no) 1989-02-07
RU1799383C (ru) 1993-02-28
ZW1489A1 (en) 1989-08-02
FI890438A0 (fi) 1989-01-30
AU2969289A (en) 1989-08-10
KR890013013A (ko) 1989-09-20
HU204794B (en) 1992-02-28
CN1036204A (zh) 1989-10-11
NO168424B (no) 1991-11-11
CA1324378C (en) 1993-11-16
EP0335483A3 (en) 1991-12-18
NZ227833A (en) 1991-09-25
DK55089A (da) 1989-08-09
DD283393A5 (de) 1990-10-10
NO890515L (no) 1989-08-09
BR8900541A (pt) 1989-10-03
DK55089D0 (da) 1989-02-07
IT1233860B (it) 1992-04-21
AU616240B2 (en) 1991-10-24
RO104070B1 (en) 1993-07-20
RO105964B1 (ro) 1993-01-30
AU7947991A (en) 1991-09-12
JPH01246281A (ja) 1989-10-02
FI890438A (fi) 1989-08-09
US5053422A (en) 1991-10-01
HUT53363A (en) 1990-10-28
PT89657B (pt) 1994-02-28
PL158198B1 (pl) 1992-08-31
EP0335483A2 (en) 1989-10-04
HU203104B (en) 1991-05-28
NO168424C (no) 1992-02-19
DD291996A5 (de) 1991-07-18
PT89657A (pt) 1989-10-04
HU904864D0 (en) 1991-01-28

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