ZA884339B - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
ZA884339B
ZA884339B ZA884339A ZA884339A ZA884339B ZA 884339 B ZA884339 B ZA 884339B ZA 884339 A ZA884339 A ZA 884339A ZA 884339 A ZA884339 A ZA 884339A ZA 884339 B ZA884339 B ZA 884339B
Authority
ZA
South Africa
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
ZA884339A
Other languages
English (en)
Inventor
Klaus Peter Boegesoe
Peter Boegesoe Klaus
Klaus Gundertofte Jensen
Gundertofte Jensen Klaus
Ejner Knud Moltzen
Knud Moltzen Ejner
Hendrik Pedersen
Pedersen Hendrik
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of ZA884339B publication Critical patent/ZA884339B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA884339A 1987-06-24 1988-06-17 Heterocyclic compounds ZA884339B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878714789A GB8714789D0 (en) 1987-06-24 1987-06-24 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
ZA884339B true ZA884339B (en) 1989-05-30

Family

ID=10619472

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA884339A ZA884339B (en) 1987-06-24 1988-06-17 Heterocyclic compounds

Country Status (19)

Country Link
US (3) US4866077A (fr)
EP (1) EP0296721B1 (fr)
JP (1) JP2703268B2 (fr)
AU (1) AU615917B2 (fr)
BR (1) BR1100658A (fr)
CA (1) CA1340458C (fr)
DE (1) DE3881970T2 (fr)
DK (1) DK168600B1 (fr)
ES (1) ES2056928T3 (fr)
FI (1) FI93356C (fr)
GB (1) GB8714789D0 (fr)
HK (1) HK84194A (fr)
HU (1) HU210809A9 (fr)
IE (1) IE61694B1 (fr)
IL (1) IL86618A (fr)
NO (1) NO174051C (fr)
NZ (1) NZ224868A (fr)
PT (1) PT87820B (fr)
ZA (1) ZA884339B (fr)

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IT1229491B (it) * 1988-12-28 1991-09-03 Roussel Maestretti S P A Ora R Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
JP3003148B2 (ja) * 1989-01-05 2000-01-24 藤沢薬品工業株式会社 チアゾール化合物、その製造法およびそれを含有する医薬組成物
US4902695A (en) * 1989-02-13 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
US5328925A (en) * 1989-02-22 1994-07-12 Novo Nordisk A/S Piperidine compounds and their use
US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
US5264444A (en) * 1989-02-22 1993-11-23 Novo Nordisk A/S Piperidine compounds and use
EP0402056A3 (fr) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Composés azabicycliques, procédé pour leur préparation et compositions pharmaceutiques les contenant
ATE136031T1 (de) * 1989-10-07 1996-04-15 Beecham Group Plc Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
IE911994A1 (en) * 1990-07-03 1992-01-15 Akzo Nv 5-isothiazolamine derivatives
US5418240A (en) * 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
USRE35822E (en) * 1990-08-21 1998-06-09 Novo Nordisk A/S Heterocyclic compounds
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
WO1992009280A1 (fr) * 1990-11-29 1992-06-11 Allergan, Inc. Utilisation de derives de pyridine pour traiter l'hypertension oculaire
WO1992016239A1 (fr) * 1991-03-13 1992-10-01 The Regents Of The University Of Minnesota Agents radiopharmaceutiques pour la detection de la maladie d'alzheimer
IE922270A1 (en) * 1991-07-26 1993-01-27 Akzo Nv Pyrazole derivatives
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists
WO1993014089A1 (fr) * 1992-01-13 1993-07-22 Novo Nordisk A/S Composes heterocycliques, leur preparation et leur utilisation
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
ES2133416T3 (es) * 1992-10-23 1999-09-16 Merck Sharp & Dohme Ligandos de subtipos de receptores de dopamina.
US5753683A (en) * 1993-08-19 1998-05-19 Novo Nordisk A/S Antipsychotic method
US5612351A (en) * 1994-11-08 1997-03-18 Novo Nordisk A/S Method of treating urinary bladder dysfunctions
US5668148A (en) * 1995-04-20 1997-09-16 Merck & Co., Inc. Alpha1a adrenergic receptor antagonists
US5994373A (en) * 1995-06-29 1999-11-30 Novo Nordisk A/S Novo Alle Dk 2880 Substituted azacyclic compounds
JPH11514654A (ja) * 1995-11-06 1999-12-14 ハー・ルンドベック・アクチェゼルスカベット 外傷による脳損傷の治療方法
AU2568597A (en) * 1996-04-24 1997-11-12 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
ATE273007T1 (de) 1997-05-29 2004-08-15 Lundbeck & Co As H Behandlung der schizophrenie und der psychose
AR013096A1 (es) * 1997-07-01 2000-12-13 Lundbeck & Co As H Sal de adicion de acido maleico de 5-(2-etil-2-h-tetrazol-5-il)-1-metil- 1,2,3,6-tetrahidropiridina, composicion farmaceutica que la contiene, su usoen terapia y metodo de preparacion de la misma.
AU9432498A (en) * 1997-10-02 1999-04-27 H. Lundbeck A/S Granular preparations of 5-(2-ethyl- 2(h)-tetrazol- 5-yl)-1-methyl-1, 2,3,6-tetrahydropyridine
JP2003527305A (ja) * 1998-07-27 2003-09-16 イーライ・リリー・アンド・カンパニー 不安症の処置
AU6686700A (en) * 1999-08-23 2001-03-19 H. Lundbeck A/S Treatment of urinary incontinence
WO2001078723A1 (fr) * 2000-04-12 2001-10-25 Smithkline Beecham Corporation Composes et procedes
CA2439593C (fr) * 2001-04-05 2010-02-09 Torrent Pharmaceuticals Ltd. Composes heterocycliques pour des complications vasculaires diabetiques et liees au vieillissement
US20030069597A1 (en) * 2001-10-10 2003-04-10 Scimed Life Systems, Inc. Loading tool
GEP20074045B (en) 2001-11-19 2007-02-26 Elan Pharm Inc (4-phenyl) piperidin-3-yl-phenylcarboxylate derivatives and related compounds as beta-secretase inhibitors for the treatment of alzheimer's disease
CN100400519C (zh) 2002-12-18 2008-07-09 拜尔农科股份公司 N-(取代的芳基甲基)-4-(二取代的甲基)哌啶和哌嗪
WO2004058148A2 (fr) * 2002-12-20 2004-07-15 Merck & Co., Inc. Inhibiteurs de la kinesine mitotique
CA2556589A1 (fr) * 2004-02-24 2005-09-01 Bioaxone Therapeutique Inc. Derives de piperidine substitues en position 4
US20060224175A1 (en) * 2005-03-29 2006-10-05 Vrba Anthony C Methods and apparatuses for disposition of a medical device onto an elongate medical device
CA2620333A1 (fr) * 2005-08-26 2007-03-01 Braincells, Inc. Neurogenese par modulation du recepteur muscarinique
EP2258359A3 (fr) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (fr) 2005-10-31 2007-05-10 Braincells, Inc. Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
EP2026813A2 (fr) 2006-05-09 2009-02-25 Braincells, Inc. Neurogenèse induite par le récepteur 5ht
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス，インコーポレイティド ４−アシルアミノピリジン誘導体を含む組み合わせ
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US8084473B2 (en) 2007-04-24 2011-12-27 Solvay Pharmaceuticals B.V. Heterocyclic compounds with affinity to muscarinic receptors
JP2010525020A (ja) * 2007-04-24 2010-07-22 ソルベイ・フアーマシユーチカルズ・ベー・ブイ ムスカリン性受容体への親和性を有する複素環式化合物
JP2011520905A (ja) 2008-05-15 2011-07-21 ザ・ユニバーシティ・オブ・トレド 向知性剤としてのムスカリンアゴニスト
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WO2010128528A2 (fr) * 2009-05-07 2010-11-11 Torrent Pharmaceuticals Limited Nouveaux composés hétérocycliques
ES2603032T3 (es) 2010-07-15 2017-02-23 Bayer Intellectual Property Gmbh Compuestos de 3-piridil-heteroarilcarboxamida como pesticidas
BR112013009823A2 (pt) 2010-10-22 2016-07-05 Bayer Ip Gmbh novos compostos heterocíclicos como pesticidas
US9549928B2 (en) 2011-04-29 2017-01-24 The University Of Toledo Muscarinic agonists as enhancers of cognitive flexibility
CN103848850B (zh) * 2013-08-28 2016-03-23 沈阳东瑞精细化工有限公司 一种舒巴坦的制备方法
US10149856B2 (en) 2015-01-26 2018-12-11 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10857157B2 (en) 2015-01-26 2020-12-08 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10106525B2 (en) 2015-01-26 2018-10-23 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
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US2659739A (en) 1950-04-14 1953-11-17 Eastman Kodak Co 1-hydroxy-4-beta-cyanopropylamino-anthraquinone and process for preparing same
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EP0372125A1 (fr) * 1988-11-08 1990-06-13 Akzo N.V. Dérivés de thiazole et d'oxazole

Also Published As

Publication number Publication date
US4866077A (en) 1989-09-12
EP0296721B1 (fr) 1993-06-23
BR1100658A (pt) 1999-08-31
NO882799D0 (no) 1988-06-23
ES2056928T3 (es) 1994-10-16
DE3881970T2 (de) 1993-11-11
JP2703268B2 (ja) 1998-01-26
HU210809A9 (en) 1995-08-28
DE3881970D1 (de) 1993-07-29
USRE36374E (en) 1999-11-02
IL86618A0 (en) 1988-11-30
JPS6422869A (en) 1989-01-25
IE881631L (en) 1988-12-24
EP0296721A2 (fr) 1988-12-28
GB8714789D0 (en) 1987-07-29
NO174051B (no) 1993-11-29
AU1828288A (en) 1989-01-05
NO882799L (no) 1988-12-27
NO174051C (no) 1994-03-09
IL86618A (en) 1992-07-15
AU615917B2 (en) 1991-10-17
CA1340458C (fr) 1999-03-23
FI883064A0 (fi) 1988-06-23
NZ224868A (en) 1990-07-26
FI93356B (fi) 1994-12-15
FI93356C (fi) 1995-03-27
PT87820B (pt) 1992-10-30
US4925858A (en) 1990-05-15
DK321688D0 (da) 1988-06-13
FI883064A (fi) 1988-12-25
DK168600B1 (da) 1994-05-02
DK321688A (da) 1988-12-25
PT87820A (pt) 1989-05-31
EP0296721A3 (en) 1990-04-25
IE61694B1 (en) 1994-11-16
HK84194A (en) 1994-08-26

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