HK84194A - Heterocyclic compounds - Google Patents

Heterocyclic compounds

Info

Publication number
HK84194A
HK84194A HK84194A HK84194A HK84194A HK 84194 A HK84194 A HK 84194A HK 84194 A HK84194 A HK 84194A HK 84194 A HK84194 A HK 84194A HK 84194 A HK84194 A HK 84194A
Authority
HK
Hong Kong
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
HK84194A
Other languages
English (en)
Inventor
Klaus Peter Bogeso
Klaus Gundertofte Jensen
Ejner Knud Moltzen
Pedersen Henrik
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of HK84194A publication Critical patent/HK84194A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK84194A 1987-06-24 1994-08-18 Heterocyclic compounds HK84194A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878714789A GB8714789D0 (en) 1987-06-24 1987-06-24 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
HK84194A true HK84194A (en) 1994-08-26

Family

ID=10619472

Family Applications (1)

Application Number Title Priority Date Filing Date
HK84194A HK84194A (en) 1987-06-24 1994-08-18 Heterocyclic compounds

Country Status (19)

Country Link
US (3) US4866077A (fr)
EP (1) EP0296721B1 (fr)
JP (1) JP2703268B2 (fr)
AU (1) AU615917B2 (fr)
BR (1) BR1100658A (fr)
CA (1) CA1340458C (fr)
DE (1) DE3881970T2 (fr)
DK (1) DK168600B1 (fr)
ES (1) ES2056928T3 (fr)
FI (1) FI93356C (fr)
GB (1) GB8714789D0 (fr)
HK (1) HK84194A (fr)
HU (1) HU210809A9 (fr)
IE (1) IE61694B1 (fr)
IL (1) IL86618A (fr)
NO (1) NO174051C (fr)
NZ (1) NZ224868A (fr)
PT (1) PT87820B (fr)
ZA (1) ZA884339B (fr)

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US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
US5328925A (en) * 1989-02-22 1994-07-12 Novo Nordisk A/S Piperidine compounds and their use
US5264444A (en) * 1989-02-22 1993-11-23 Novo Nordisk A/S Piperidine compounds and use
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
EP0402056A3 (fr) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Composés azabicycliques, procédé pour leur préparation et compositions pharmaceutiques les contenant
DE69026197T2 (de) * 1989-10-07 1997-01-09 Beecham Group Plc Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
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DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5418240A (en) * 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
USRE35822E (en) * 1990-08-21 1998-06-09 Novo Nordisk A/S Heterocyclic compounds
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WO1992016239A1 (fr) * 1991-03-13 1992-10-01 The Regents Of The University Of Minnesota Agents radiopharmaceutiques pour la detection de la maladie d'alzheimer
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US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists
WO1993014089A1 (fr) * 1992-01-13 1993-07-22 Novo Nordisk A/S Composes heterocycliques, leur preparation et leur utilisation
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
CA2146019A1 (fr) * 1992-10-23 1994-05-11 Howard B. Broughton Ligands de sous-types de recepteurs dopaminergiques
US5753683A (en) * 1993-08-19 1998-05-19 Novo Nordisk A/S Antipsychotic method
US5612351A (en) * 1994-11-08 1997-03-18 Novo Nordisk A/S Method of treating urinary bladder dysfunctions
US5668148A (en) * 1995-04-20 1997-09-16 Merck & Co., Inc. Alpha1a adrenergic receptor antagonists
EP0835255A1 (fr) * 1995-06-29 1998-04-15 Novo Nordisk A/S Nouveaux composes azacycliques substitues
TR199800801T2 (xx) * 1995-11-06 1998-08-21 H. Lund-Beck A/S Travmatik beyin yaralanmalar�n�n tedavisi.
WO1997040045A1 (fr) * 1996-04-24 1997-10-30 Novo Nordisk A/S Composes heterocycliques, preparation et utilisation
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
JP2002500651A (ja) 1997-05-29 2002-01-08 ハー・ルンドベック・アクティーゼルスカブ 精神分裂病及び精神病の治療方法
AR013096A1 (es) * 1997-07-01 2000-12-13 Lundbeck & Co As H Sal de adicion de acido maleico de 5-(2-etil-2-h-tetrazol-5-il)-1-metil- 1,2,3,6-tetrahidropiridina, composicion farmaceutica que la contiene, su usoen terapia y metodo de preparacion de la misma.
WO1999017771A1 (fr) * 1997-10-02 1999-04-15 H. Lundbeck A/S Preparations granulaires de 5-(2-ethyle- 2h-tetrazol- 5-yle)-1-methyle-1, 2,3,6-tetrahydropyridine
IL140540A0 (en) * 1998-07-27 2002-02-10 Lilly Co Eli Treatment of anxiety disorders
AR025353A1 (es) * 1999-08-23 2002-11-20 Lundbeck & Co As H Tratamiento de la incontinencia urinaria
US20030220371A1 (en) * 2000-04-12 2003-11-27 Kallander Lara S. Compounds and methods
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US20030069597A1 (en) * 2001-10-10 2003-04-10 Scimed Life Systems, Inc. Loading tool
EP1448200A2 (fr) * 2001-11-19 2004-08-25 Elan Pharmaceuticals, Inc. Piperidines et piperazines 3,4-disubstituees, 3,5-disubstituees et 3,4,5-substituees
CN100400519C (zh) 2002-12-18 2008-07-09 拜尔农科股份公司 N-(取代的芳基甲基)-4-(二取代的甲基)哌啶和哌嗪
US7622468B2 (en) * 2002-12-20 2009-11-24 Merck & Co. Inc. Mitotic kinesin inhibitors
EP1720874A4 (fr) * 2004-02-24 2010-03-03 Bioaxone Therapeutique Inc Derives de piperidine substitues en position 4
US20060224175A1 (en) * 2005-03-29 2006-10-05 Vrba Anthony C Methods and apparatuses for disposition of a medical device onto an elongate medical device
EP2258359A3 (fr) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenèse par modulation des récepteurs muscariniques avec sabcomeline
WO2007025177A2 (fr) * 2005-08-26 2007-03-01 Braincells, Inc. Neurogenese par modulation du recepteur muscarinique
EP1940389A2 (fr) 2005-10-21 2008-07-09 Braincells, Inc. Modulation de la neurogenese par inhibition de la pde
CA2625210A1 (fr) 2005-10-31 2007-05-10 Braincells, Inc. Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
WO2007134077A2 (fr) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenèse induite par le récepteur 5ht
CA2651813A1 (fr) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenese par modulation de l'angiotensine
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス，インコーポレイティド ４−アシルアミノピリジン誘導体を含む組み合わせ
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008129054A2 (fr) * 2007-04-24 2008-10-30 Solvay Pharmaceuticals B.V. Composés hétérocycliques présentant une affinité pour les récepteurs muscariniques
US8084473B2 (en) 2007-04-24 2011-12-27 Solvay Pharmaceuticals B.V. Heterocyclic compounds with affinity to muscarinic receptors
EP2296471A4 (fr) 2008-05-15 2012-03-14 Univ Toledo Agonistes muscariniques servant de stimulateurs cognitifs
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TW201102380A (en) * 2009-05-07 2011-01-16 Torrent Pharmaceuticals Ltd Novel heterocyclic compounds
EP2593447B1 (fr) 2010-07-15 2016-08-17 Bayer Intellectual Property GmbH Composés de 3-pyridyl-heteroarylcarboxamide comme d'agents de lutte contre les nuisibles
EP2630133A1 (fr) 2010-10-22 2013-08-28 Bayer Intellectual Property GmbH Nouveaux composés hétérocycliques utilisés en tant qu'agents pour lutter contre des nuisibles
US9549928B2 (en) 2011-04-29 2017-01-24 The University Of Toledo Muscarinic agonists as enhancers of cognitive flexibility
CN103848850B (zh) * 2013-08-28 2016-03-23 沈阳东瑞精细化工有限公司 一种舒巴坦的制备方法
US10149856B2 (en) 2015-01-26 2018-12-11 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10106525B2 (en) 2015-01-26 2018-10-23 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US10857157B2 (en) 2015-01-26 2020-12-08 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US11198680B2 (en) 2016-12-21 2021-12-14 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
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IL83275A (en) * 1986-09-08 1994-02-27 Novo Nordisk As Compounds 1,2, 4-Oxadiazolyl Pipridine Transformed, their preparation and pharmaceutical preparations containing them
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EP0372125A1 (fr) * 1988-11-08 1990-06-13 Akzo N.V. Dérivés de thiazole et d'oxazole

Also Published As

Publication number Publication date
FI93356B (fi) 1994-12-15
AU1828288A (en) 1989-01-05
IE881631L (en) 1988-12-24
DK321688A (da) 1988-12-25
NZ224868A (en) 1990-07-26
GB8714789D0 (en) 1987-07-29
PT87820B (pt) 1992-10-30
NO882799D0 (no) 1988-06-23
FI883064A (fi) 1988-12-25
EP0296721A2 (fr) 1988-12-28
IE61694B1 (en) 1994-11-16
JP2703268B2 (ja) 1998-01-26
US4925858A (en) 1990-05-15
DK168600B1 (da) 1994-05-02
ES2056928T3 (es) 1994-10-16
HU210809A9 (en) 1995-08-28
DE3881970T2 (de) 1993-11-11
NO174051B (no) 1993-11-29
ZA884339B (en) 1989-05-30
USRE36374E (en) 1999-11-02
JPS6422869A (en) 1989-01-25
BR1100658A (pt) 1999-08-31
NO882799L (no) 1988-12-27
IL86618A0 (en) 1988-11-30
AU615917B2 (en) 1991-10-17
CA1340458C (fr) 1999-03-23
US4866077A (en) 1989-09-12
NO174051C (no) 1994-03-09
EP0296721A3 (en) 1990-04-25
PT87820A (pt) 1989-05-31
FI93356C (fi) 1995-03-27
EP0296721B1 (fr) 1993-06-23
DE3881970D1 (de) 1993-07-29
DK321688D0 (da) 1988-06-13
FI883064A0 (fi) 1988-06-23
IL86618A (en) 1992-07-15

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Effective date: 20080526