ZA86838B - Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same - Google Patents

Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same

Info

Publication number
ZA86838B
ZA86838B ZA86838A ZA86838A ZA86838B ZA 86838 B ZA86838 B ZA 86838B ZA 86838 A ZA86838 A ZA 86838A ZA 86838 A ZA86838 A ZA 86838A ZA 86838 B ZA86838 B ZA 86838B
Authority
ZA
South Africa
Prior art keywords
same
tetracyclines
preparing
methods
possessing anti
Prior art date
Application number
ZA86838A
Other languages
English (en)
Inventor
Thomas F Mcnamara
Nungavaram S Ramamurthy
Lorne M Golub
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Publication of ZA86838B publication Critical patent/ZA86838B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
ZA86838A 1985-02-07 1986-02-05 Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same ZA86838B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/699,048 US4704383A (en) 1983-12-29 1985-02-07 Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same

Publications (1)

Publication Number Publication Date
ZA86838B true ZA86838B (en) 1986-10-29

Family

ID=24807719

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA86838A ZA86838B (en) 1985-02-07 1986-02-05 Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same

Country Status (12)

Country Link
US (1) US4704383A (ja)
EP (1) EP0195906B1 (ja)
JP (1) JP2676080B2 (ja)
AT (1) ATE81460T1 (ja)
AU (1) AU583884B2 (ja)
CA (1) CA1297410C (ja)
DE (1) DE3686956T2 (ja)
DK (1) DK174997B1 (ja)
ES (1) ES8708182A1 (ja)
GR (1) GR860333B (ja)
IE (1) IE58813B1 (ja)
ZA (1) ZA86838B (ja)

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JP3016587B2 (ja) * 1989-12-04 2000-03-06 ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク 非ステロイド抗炎症剤及びテトラサイクリンの配合
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US5223248A (en) * 1991-02-11 1993-06-29 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing antiplaque properties
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CA2094874C (en) * 1992-04-27 2003-02-11 Thomas F. Mcnamara Non-antibacterial tetracycline compositons possessing antiplaque properties
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US5922340A (en) 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5523297A (en) * 1993-03-02 1996-06-04 The Research Foundation Of State University Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
US6043231A (en) * 1993-03-02 2000-03-28 The Research Foundation Of State Univ. Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
US5641636A (en) * 1994-05-20 1997-06-24 University Of Pennsylvania Method of predicting fetal membrane rupture based on matrix metalloproteinase-9 activity
US6140099A (en) * 1994-05-20 2000-10-31 The Trustees Of The University Of Pennsylvania Method of delaying fetal membrane rupture by inhibiting matrix metalloproteinase-9 activity
KR100245395B1 (ko) 1995-06-09 2000-03-02 그린 마틴, 브라이언 쥐 테슬리 장기간의 국소 마취를 제공하는 제형 및 그 방법
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US5827840A (en) * 1996-08-01 1998-10-27 The Research Foundation Of State University Of New York Promotion of wound healing by chemically-modified tetracyclines
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US5773430A (en) * 1997-03-13 1998-06-30 Research Foundation Of State University Of New York Serine proteinase inhibitory activity by hydrophobic tetracycline
JP2908375B2 (ja) * 1997-04-01 1999-06-21 ザ リサーチ ファンデーション オブ ステート ユニバーシティ オブ ニューヨーク 非抗バクテリア性テトラサイクリン組成物
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AU8918898A (en) 1997-08-25 1999-03-16 Harold Brem Prevention of adhesions and excessive scar formation using angiogenesis inhibi tors
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ES2302373T3 (es) * 1998-02-13 2008-07-01 Nutramax Laboratories, Inc. Agentes y metodos para la proteccion, tratamiento y reparacion de tejidos conectivos.
US6277061B1 (en) * 1998-03-31 2001-08-21 The Research Foundation Of State University Of New York Method of inhibiting membrane-type matrix metalloproteinase
RU2211693C2 (ru) * 1998-05-27 2003-09-10 Юроселтик С.А. Препараты для введения противовоспалительных, особенно антисептических веществ и/или веществ, способствующих заживлению ран, в верхние дыхательные пути и/или в ухо
US6015804A (en) * 1998-09-11 2000-01-18 The Research Foundation Of State University Of New York Method of using tetracycline compounds to enhance interleukin-10 production
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US6294694B1 (en) 1999-06-04 2001-09-25 Wisconsin Alumni Research Foundation Matrix metalloproteinase inhibitors and method of using same
US6673843B2 (en) * 1999-06-30 2004-01-06 Emory University Curcumin and curcuminoid inhibition of angiogenesis
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US7211267B2 (en) * 2001-04-05 2007-05-01 Collagenex Pharmaceuticals, Inc. Methods of treating acne
JP2004537544A (ja) 2001-07-13 2004-12-16 パラテック ファーマシューティカルズ インコーポレイテッド 標的治療活性を有するテトラサイクリン化合物
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
EP1439843A4 (en) * 2001-10-05 2007-01-03 Tetragenex Pharmaceuticals Inc TETRACYCLINE DERIVATIVES AND METHODS OF USE
US7056902B2 (en) 2002-01-08 2006-06-06 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
US20090011991A1 (en) * 2002-03-08 2009-01-08 Emory University Novel Curcuminoid-Factor VIIA Constructs as Suppressors of Tumor Growth and Angiogenesis
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EP1496742B1 (en) * 2002-03-29 2010-11-24 The Research Foundation Of State University Of New York Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins
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BRPI0602372B8 (pt) 2006-05-18 2021-06-22 Einco Biomaterial Ltda processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado
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CA2892739A1 (en) * 2006-12-21 2008-07-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
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EA201070233A1 (ru) * 2007-07-06 2010-08-30 Паратек Фармасьютикалс, Инк. Способы синтеза замещённых соединений тетрациклина (варианты)
TW202021946A (zh) 2008-05-23 2020-06-16 美商派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
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Also Published As

Publication number Publication date
DE3686956T2 (de) 1993-05-06
US4704383A (en) 1987-11-03
AU583884B2 (en) 1989-05-11
DK174997B1 (da) 2004-04-13
CA1297410C (en) 1992-03-17
IE58813B1 (en) 1993-11-17
GR860333B (en) 1986-06-13
DK62286D0 (da) 1986-02-07
JP2676080B2 (ja) 1997-11-12
ATE81460T1 (de) 1992-10-15
JPS61243023A (ja) 1986-10-29
EP0195906B1 (en) 1992-10-14
EP0195906A2 (en) 1986-10-01
ES8708182A1 (es) 1987-10-01
ES551701A0 (es) 1987-10-01
IE860333L (en) 1986-08-07
DE3686956D1 (de) 1992-11-19
EP0195906A3 (en) 1988-10-19
DK62286A (da) 1986-08-08
AU5298486A (en) 1986-08-14

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