ES8802468A1 - Metodo de preparar medicamentos que incluyen un agente buscador de hueso y un inhibidor de anhidrasa carbonica, para impedir y curar enfermedades oseas. - Google Patents
Metodo de preparar medicamentos que incluyen un agente buscador de hueso y un inhibidor de anhidrasa carbonica, para impedir y curar enfermedades oseas.Info
- Publication number
- ES8802468A1 ES8802468A1 ES555118A ES555118A ES8802468A1 ES 8802468 A1 ES8802468 A1 ES 8802468A1 ES 555118 A ES555118 A ES 555118A ES 555118 A ES555118 A ES 555118A ES 8802468 A1 ES8802468 A1 ES 8802468A1
- Authority
- ES
- Spain
- Prior art keywords
- carbonic anhydrase
- bone
- targeted inhibitors
- bone targeted
- prophylaxis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
METODO DE PREPARAR MEDICAMENTOS QUE INCLUYEN UN AGENTE BUSCADOR DE HUESO Y UN INHIBIDOR ANANHIDRASA CARBONICA EN EL QUE SE HACE REACCIONAR UN AGENTE BUSCADOR DE HUESO, UNA TETRACICLINA O UN DIFOSFATO, QUE CONTIENE UN DICLORURO DE ADIPOILO COMO AGENTE PUENTE, CON UN INHIBIDOR DE ENCIMA ANHIDRASA CARBONICA, TAL COMO UNA SULFONAMIDA HETEROCICLICA O UN IMIDAZOL, EN UN DISOLVENTE ORGANICO A TEMPERATURA DESDE LA AMBIENTAL HASTA LA DE REFLUJO DE LA MEZCLA DE REACCION, DURANTE EL TIEMPO SUFICIENTE PARA QUE SE FORMEN DICHOS COMPUESTOS. TIENE APLICACION MEDICA PARA EL TRATAMIENTO DE PROFILAXIS DE TRASTORNOS OSEOS DEGENERATIVOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73087385A | 1985-05-02 | 1985-05-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8802468A1 true ES8802468A1 (es) | 1988-07-16 |
ES555118A0 ES555118A0 (es) | 1988-07-16 |
Family
ID=24937140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES555118A Expired ES8802468A1 (es) | 1985-05-02 | 1986-04-30 | Metodo de preparar medicamentos que incluyen un agente buscador de hueso y un inhibidor de anhidrasa carbonica, para impedir y curar enfermedades oseas. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0201057B1 (es) |
JP (1) | JP2578098B2 (es) |
AT (1) | ATE82854T1 (es) |
DE (1) | DE3687181T2 (es) |
DK (1) | DK201486A (es) |
ES (1) | ES8802468A1 (es) |
GR (1) | GR861167B (es) |
IE (1) | IE59801B1 (es) |
IL (1) | IL78661A (es) |
PT (1) | PT82499B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0341961A3 (en) * | 1988-05-09 | 1990-06-20 | Merck & Co. Inc. | Polymalonic acids as boneaffinity agents |
JPH0778024B2 (ja) * | 1988-10-14 | 1995-08-23 | 藤沢薬品工業株式会社 | 医薬化合物とジホスホン酸誘導体の結合体を含有する医薬用製剤 |
US4990523A (en) * | 1989-06-19 | 1991-02-05 | A. H. Robins Company, Incorporated | Treatment of chronic inflammatory joint disease with arylsulfonamides |
EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
US5183815A (en) * | 1991-01-22 | 1993-02-02 | Merck & Co., Inc. | Bone acting agents |
JP3377856B2 (ja) * | 1993-03-25 | 2003-02-17 | イスクラ産業株式会社 | 骨吸収抑制・骨形成促進化合物 |
US5698542A (en) * | 1993-12-29 | 1997-12-16 | Iskra Industry Co., Ltd. | Bone resorption inhibition/osteogenesis promotion pharmaceutical composition |
US5880111A (en) * | 1995-06-07 | 1999-03-09 | Farcasiu; Dan | Therapeutic derivations of diphosphonates |
PL336231A1 (en) | 1997-02-13 | 2000-06-19 | Bone Care International | System for aimed therapeutic delivery of vitamin d compounds |
DE19828068C2 (de) * | 1998-06-24 | 2003-12-18 | Peter Dietsch | Mittel zur spezifischen Hemmung osteoklastärer Knochenresorption |
US6214381B1 (en) | 1998-09-08 | 2001-04-10 | Effcon, Inc. | Methazolamide composition and method of use |
AU4682700A (en) * | 1999-04-30 | 2000-11-17 | Research Corporation Technologies, Inc. | Bone targeting agents for osteoporosis |
US6436386B1 (en) * | 2000-11-14 | 2002-08-20 | Shearwater Corporation | Hydroxyapatite-targeting poly (ethylene glycol) and related polymers |
US7829074B2 (en) | 2001-10-18 | 2010-11-09 | Nektar Therapeutics | Hydroxypatite-targeting poly(ethylene glycol) and related polymers |
US9980946B1 (en) | 2017-01-25 | 2018-05-29 | Effcon Laboratories, Inc. | Extended release methazolamide formulation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4704383A (en) * | 1983-12-29 | 1987-11-03 | The Research Foundation Of State University Of New York | Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same |
US4666897A (en) * | 1983-12-29 | 1987-05-19 | Research Foundation Of State University | Inhibition of mammalian collagenolytic enzymes by tetracyclines |
DE3587956T2 (de) * | 1984-04-30 | 1995-05-24 | Procter & Gamble | Ausrüstung für die Verwendung bei der Behandlung von Osteoporose. |
-
1986
- 1986-04-30 GR GR861167A patent/GR861167B/el unknown
- 1986-04-30 ES ES555118A patent/ES8802468A1/es not_active Expired
- 1986-05-01 IE IE114886A patent/IE59801B1/en not_active IP Right Cessation
- 1986-05-01 DK DK201486A patent/DK201486A/da not_active Application Discontinuation
- 1986-05-02 JP JP61102965A patent/JP2578098B2/ja not_active Expired - Lifetime
- 1986-05-02 DE DE8686106031T patent/DE3687181T2/de not_active Expired - Fee Related
- 1986-05-02 IL IL8678661A patent/IL78661A/xx not_active IP Right Cessation
- 1986-05-02 PT PT82499A patent/PT82499B/pt not_active IP Right Cessation
- 1986-05-02 AT AT86106031T patent/ATE82854T1/de not_active IP Right Cessation
- 1986-05-02 EP EP86106031A patent/EP0201057B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0201057A2 (en) | 1986-11-12 |
GR861167B (en) | 1986-09-30 |
JP2578098B2 (ja) | 1997-02-05 |
ATE82854T1 (de) | 1992-12-15 |
EP0201057B1 (en) | 1992-12-02 |
DE3687181T2 (de) | 1993-04-15 |
JPS6226256A (ja) | 1987-02-04 |
IL78661A0 (en) | 1986-08-31 |
DK201486A (da) | 1986-11-04 |
DK201486D0 (da) | 1986-05-01 |
IE59801B1 (en) | 1994-04-06 |
IL78661A (en) | 1992-08-18 |
IE861148L (en) | 1986-11-02 |
PT82499B (pt) | 1988-10-14 |
DE3687181D1 (de) | 1993-01-14 |
EP0201057A3 (en) | 1989-10-18 |
PT82499A (en) | 1986-06-01 |
ES555118A0 (es) | 1988-07-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20020506 |