ZA865262B - Distamycin derivatives and process for their preparation - Google Patents

Distamycin derivatives and process for their preparation

Info

Publication number
ZA865262B
ZA865262B ZA865262A ZA865262A ZA865262B ZA 865262 B ZA865262 B ZA 865262B ZA 865262 A ZA865262 A ZA 865262A ZA 865262 A ZA865262 A ZA 865262A ZA 865262 B ZA865262 B ZA 865262B
Authority
ZA
South Africa
Prior art keywords
preparation
distamycin derivatives
distamycin
derivatives
Prior art date
Application number
ZA865262A
Other languages
English (en)
Inventor
Federico Arcamone
Nicola Mongelli Fabio Animati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ZA865262B publication Critical patent/ZA865262B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA865262A 1985-07-16 1986-07-15 Distamycin derivatives and process for their preparation ZA865262B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858517923A GB8517923D0 (en) 1985-07-16 1985-07-16 Distamycin derivatives

Publications (1)

Publication Number Publication Date
ZA865262B true ZA865262B (en) 1987-03-25

Family

ID=10582358

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA865262A ZA865262B (en) 1985-07-16 1986-07-15 Distamycin derivatives and process for their preparation

Country Status (29)

Country Link
US (1) US4738980A (no)
JP (1) JPH0780842B2 (no)
KR (1) KR940003495B1 (no)
CN (2) CN85103908A (no)
AT (1) AT386822B (no)
AU (1) AU584723B2 (no)
BE (1) BE905109A (no)
CA (1) CA1247627A (no)
CH (1) CH671958A5 (no)
CZ (1) CZ277823B6 (no)
DE (1) DE3623853C2 (no)
DK (1) DK335886A (no)
ES (1) ES2000346A6 (no)
FI (1) FI82929C (no)
FR (1) FR2585019B1 (no)
GB (2) GB8517923D0 (no)
GR (1) GR861840B (no)
HU (1) HU198087B (no)
IE (1) IE59275B1 (no)
IL (1) IL79401A (no)
IT (1) IT1213103B (no)
NL (1) NL8601838A (no)
NO (1) NO169014C (no)
NZ (1) NZ216828A (no)
PH (1) PH23459A (no)
PT (1) PT82985B (no)
SE (1) SE468594B (no)
SU (2) SU1535378A3 (no)
ZA (1) ZA865262B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
US5049579A (en) * 1986-05-20 1991-09-17 Farmitalia Carlo Erba, S.R.L. Site specific alkylating agents
US5310752A (en) * 1986-05-20 1994-05-10 Farmitalia Carlo Erba Spa Site specific alkylating agents
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
WO1992013838A1 (en) * 1991-02-06 1992-08-20 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
DE4205948C2 (de) * 1992-02-24 1996-10-31 Mannesmann Ag Farbbandkassette für ein endloses Farbband
US5273991A (en) * 1992-07-29 1993-12-28 Research Corporation Technologies, Inc. Imidazole-containing compositions and methods of use thereof analogs of distamycin
US5637621A (en) * 1994-11-14 1997-06-10 Nzym, Inc. Methods and compositions for treating Botrytis infections
US5629348A (en) * 1994-11-14 1997-05-13 Nzym, Inc. Methods and compositions for treating septoria infections
EP0792262A2 (en) * 1994-11-14 1997-09-03 Nzym, Inc. Methods and compositions for treating phytopathogenic fungi infections
DE19805431A1 (de) * 1998-02-11 1999-08-12 Merck Patent Gmbh Heteroaromatische Oligoamide als Affinitätsliganden
US6555693B2 (en) 2000-03-16 2003-04-29 Genesoft, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7078536B2 (en) * 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
ITTO20010633A1 (it) * 2001-07-02 2003-01-02 Univ Ferrara Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a.
DE60326735D1 (de) 2002-08-02 2009-04-30 Genesoft Pharmaceuticals Inc Biaryl-verbindungen mit antiinfektiver wirkung
US7265129B2 (en) * 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション (ピロールカルボキサミド)−(ベンズアミド)−(イミダゾールカルボキサミド)モチーフを有する抗菌化合物
US20070269420A1 (en) * 2003-11-24 2007-11-22 Chunduru Srinivas K Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases
KR102155411B1 (ko) * 2015-03-30 2020-09-11 메이지 세이카 파루마 가부시키가이샤 에피루비신 제조방법 및 그의 신규한 제조 중간체

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA557568A (en) * 1958-05-20 J. Weiss Martin Substituted aminopyrrolecarboxylic acids and esters
CA547128A (en) * 1957-10-08 W. Waller Coy Substituted pyrrolecarboxamidopyrroles
FR86210E (no) * 1963-04-04 1966-03-23
BE666612A (no) * 1963-07-26 1965-11-03
FR141F (no) * 1963-07-26
BR6461040D0 (pt) * 1963-07-26 1973-08-02 Farmaceutici Italia Processo para preparar novos derivados de pirrol
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
NL130086C (no) * 1964-07-14 1970-06-15
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents

Also Published As

Publication number Publication date
PT82985B (pt) 1989-01-30
DE3623853C2 (de) 1995-12-21
CS541186A3 (en) 1992-09-16
ATA188786A (de) 1988-03-15
BE905109A (fr) 1987-01-15
NZ216828A (en) 1989-11-28
CH671958A5 (no) 1989-10-13
US4738980A (en) 1988-04-19
NL8601838A (nl) 1987-02-16
SE8603099D0 (sv) 1986-07-11
IL79401A (en) 1991-05-12
CN86104774A (zh) 1987-02-11
HU198087B (en) 1989-07-28
AU584723B2 (en) 1989-06-01
KR940003495B1 (ko) 1994-04-23
JPS6230755A (ja) 1987-02-09
PT82985A (pt) 1986-08-01
GB2178037A (en) 1987-02-04
SE8603099L (sv) 1987-01-17
GB8617293D0 (en) 1986-08-20
AU6020386A (en) 1987-01-22
DE3623853A1 (de) 1987-01-29
PH23459A (en) 1989-08-07
CZ277823B6 (en) 1993-06-16
DK335886A (da) 1987-01-17
SE468594B (sv) 1993-02-15
JPH0780842B2 (ja) 1995-08-30
FI862960A0 (fi) 1986-07-16
FI862960A (fi) 1987-01-17
FI82929B (fi) 1991-01-31
IL79401A0 (en) 1986-10-31
DK335886D0 (da) 1986-07-15
IE861874L (en) 1987-01-16
NO862861L (no) 1987-01-19
NO169014B (no) 1992-01-20
AT386822B (de) 1988-10-25
CN85103908A (zh) 1986-11-05
ES2000346A6 (es) 1988-02-16
HUT41814A (en) 1987-05-28
SU1535378A3 (ru) 1990-01-07
KR870001228A (ko) 1987-03-12
GB8517923D0 (en) 1985-08-21
FI82929C (fi) 1991-05-10
NO169014C (no) 1992-04-29
GB2178037B (en) 1989-07-26
NO862861D0 (no) 1986-07-15
IT1213103B (it) 1989-12-07
GR861840B (en) 1986-11-18
FR2585019B1 (fr) 1989-07-13
IE59275B1 (en) 1994-02-09
SU1538893A3 (ru) 1990-01-23
IT8621124A0 (it) 1986-07-15
FR2585019A1 (fr) 1987-01-23
CA1247627A (en) 1988-12-28
CN1026984C (zh) 1994-12-14

Similar Documents

Publication Publication Date Title
GB2178037B (en) Distamycin derivatives and process for their preparation
GR3002475T3 (en) Quinoline derivatives and processes for preparation thereof
GR861695B (en) Isoxazol and furane derivatives preparation process
EP0169114A3 (en) Human alpha-1-antitrypin derivatives and process for their preparation
ZA865263B (en) Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation
GR3002032T3 (en) Heteroaryl 3-oxo-propanenitrile derivatives and process for their preparation
GB2178036B (en) Poly-4-aminopyrrole-2-carboxamido derivatives and process for their preparation
DE3661343D1 (en) Castings and process for their preparation
GR862211B (en) Azolyl-cyclopropyl-ethanol derivatives methods for their preparation and their use
ZA865328B (en) Oxa-thia and d1-azabicycloalkane derivatives;process for their preparation and their use as pharmaceuticals
GR860870B (en) Novel benzisolelenazolonyl derivatives method for their preparation and pharmaceutical preparation containing them
GR862198B (en) Propionamidine derivatives and process for their preparation
DE3661830D1 (en) 2,4-dichlorothiazole derivatives and process for their preparation
DE3662097D1 (en) 4-mercaptobenzonitriles and process for their preparation
ZA891183B (en) Novel 16-homo-piperidino-androstane derivatives and processes for their preparation
PL249198A1 (en) Process for preparing n-phosphonmethylglycine and its derivatives
DE3661635D1 (en) Ketosultams and process for their preparation
GB2185257B (en) 10 beta-alkynyl-4, 9(11)-estradiene derivatives and process for their preparation
GB2185258B (en) 10 beta-alkynyl estrene derivatives and process for their preparation
EP0232536A3 (en) Spirodiphosphoamidate type compounds and process for their preparation
HUT40657A (en) Process for preparing imidazo-isoquinoline and imidazo-thieno-pyridine derivatives
ZA881990B (en) Dicyanoethylaryl derivatives and process for their preparation
ZA865554B (en) Antiparasitc agents and process for their preparation
BG43611A1 (en) Phenylxanthenic derivatives and method for their preparation
BG44288A1 (en) Trimethincyanine derivatives and method for their preparation