IT8621124A0 - Derivati della distamicina eprocedimento per la loro preparazione.! - Google Patents
Derivati della distamicina eprocedimento per la loro preparazione.!Info
- Publication number
- IT8621124A0 IT8621124A0 IT8621124A IT2112486A IT8621124A0 IT 8621124 A0 IT8621124 A0 IT 8621124A0 IT 8621124 A IT8621124 A IT 8621124A IT 2112486 A IT2112486 A IT 2112486A IT 8621124 A0 IT8621124 A0 IT 8621124A0
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- distamycin derivatives
- distamycin
- derivatives
- Prior art date
Links
- UPBAOYRENQEPJO-UHFFFAOYSA-N n-[5-[[5-[(3-amino-3-iminopropyl)carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]-4-formamido-1-methylpyrrole-2-carboxamide Chemical class CN1C=C(NC=O)C=C1C(=O)NC1=CN(C)C(C(=O)NC2=CN(C)C(C(=O)NCCC(N)=N)=C2)=C1 UPBAOYRENQEPJO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858517923A GB8517923D0 (en) | 1985-07-16 | 1985-07-16 | Distamycin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8621124A0 true IT8621124A0 (it) | 1986-07-15 |
| IT1213103B IT1213103B (it) | 1989-12-07 |
Family
ID=10582358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8621124A IT1213103B (it) | 1985-07-16 | 1986-07-15 | Derivati della distamicina eprocedimento per la loro preparazione.! |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US4738980A (it) |
| JP (1) | JPH0780842B2 (it) |
| KR (1) | KR940003495B1 (it) |
| CN (2) | CN85103908A (it) |
| AT (1) | AT386822B (it) |
| AU (1) | AU584723B2 (it) |
| BE (1) | BE905109A (it) |
| CA (1) | CA1247627A (it) |
| CH (1) | CH671958A5 (it) |
| CZ (1) | CZ277823B6 (it) |
| DE (1) | DE3623853C2 (it) |
| DK (1) | DK335886A (it) |
| ES (1) | ES2000346A6 (it) |
| FI (1) | FI82929C (it) |
| FR (1) | FR2585019B1 (it) |
| GB (2) | GB8517923D0 (it) |
| GR (1) | GR861840B (it) |
| HU (1) | HU198087B (it) |
| IE (1) | IE59275B1 (it) |
| IL (1) | IL79401A (it) |
| IT (1) | IT1213103B (it) |
| NL (1) | NL8601838A (it) |
| NO (1) | NO169014C (it) |
| NZ (1) | NZ216828A (it) |
| PH (1) | PH23459A (it) |
| PT (1) | PT82985B (it) |
| SE (1) | SE468594B (it) |
| SU (2) | SU1535378A3 (it) |
| ZA (1) | ZA865262B (it) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT387013B (de) * | 1985-07-16 | 1988-11-25 | Erba Farmitalia | Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten |
| GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
| US5310752A (en) * | 1986-05-20 | 1994-05-10 | Farmitalia Carlo Erba Spa | Site specific alkylating agents |
| US5049579A (en) * | 1986-05-20 | 1991-09-17 | Farmitalia Carlo Erba, S.R.L. | Site specific alkylating agents |
| GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| AU1224392A (en) * | 1991-02-06 | 1992-09-07 | Synphar Laboratories, Inc. | Oligopeptide antiretroviral agents |
| IT1262921B (it) * | 1992-01-10 | 1996-07-22 | Federico Arcamone | Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono |
| DE4205948C2 (de) * | 1992-02-24 | 1996-10-31 | Mannesmann Ag | Farbbandkassette für ein endloses Farbband |
| US5273991A (en) * | 1992-07-29 | 1993-12-28 | Research Corporation Technologies, Inc. | Imidazole-containing compositions and methods of use thereof analogs of distamycin |
| US5637621A (en) * | 1994-11-14 | 1997-06-10 | Nzym, Inc. | Methods and compositions for treating Botrytis infections |
| WO1996015104A2 (en) * | 1994-11-14 | 1996-05-23 | Nzym, Inc. | Methods and compositions for treating phytopathogenic fungi infections |
| US5629348A (en) * | 1994-11-14 | 1997-05-13 | Nzym, Inc. | Methods and compositions for treating septoria infections |
| DE19805431A1 (de) * | 1998-02-11 | 1999-08-12 | Merck Patent Gmbh | Heteroaromatische Oligoamide als Affinitätsliganden |
| DE60128551D1 (de) | 2000-03-16 | 2007-07-05 | Genesoft Inc | Geladene verbindungen mit einer nukleinsäure-bindenden einheit sowie deren verwendungen |
| US7078536B2 (en) * | 2001-03-14 | 2006-07-18 | Genesoft Pharmaceuticals, Inc. | Charged compounds comprising a nucleic acid binding moiety and uses therefor |
| GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| ITTO20010633A1 (it) * | 2001-07-02 | 2003-01-02 | Univ Ferrara | Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a. |
| WO2004012736A1 (en) | 2002-08-02 | 2004-02-12 | Genesoft Pharmaceuticals, Inc. | Biaryl compounds having anti-infective activity |
| WO2004039318A2 (en) * | 2002-10-25 | 2004-05-13 | Genesoft Pharmaceuticals, Inc. | Anti-infective biaryl compounds |
| EP1587529A4 (en) | 2002-12-10 | 2009-08-12 | Oscient Pharmaceuticals Corp | ANTIBACTERIAL COMPOUNDS HAVING A PATTERN (CARBOXAMIDE PYRROLE) - (BENZAMIDE) - (IMIDAZOLE CARBOXAMIDE) |
| US20070269420A1 (en) * | 2003-11-24 | 2007-11-22 | Chunduru Srinivas K | Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases |
| WO2016159092A1 (ja) * | 2015-03-30 | 2016-10-06 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | エピルビシンの製造方法およびその新規な製造中間体 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA557568A (en) * | 1958-05-20 | J. Weiss Martin | Substituted aminopyrrolecarboxylic acids and esters | |
| CA547128A (en) * | 1957-10-08 | W. Waller Coy | Substituted pyrrolecarboxamidopyrroles | |
| FR86210E (it) * | 1963-04-04 | 1966-03-23 | ||
| BE666612A (it) * | 1963-07-26 | 1965-11-03 | ||
| DE1795539A1 (de) * | 1963-07-26 | 1972-01-13 | Farmaceutici Italia | Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen |
| DE1470284B1 (de) * | 1963-07-26 | 1971-12-16 | Farmaceutici Italia | Beta-{1-Methyl-4-[1-methyl-4-(1-methyl-4-formylamino-pyrrol-2-carboxamido)-pyrrol-2-carboxamido]-pyrrol-2-carboxamido}-propionamidin sowie dessen Saeureadditionssalze |
| FR90359E (it) * | 1963-07-26 | 1968-02-14 | ||
| NL130086C (it) * | 1964-07-14 | 1970-06-15 | ||
| AT387013B (de) * | 1985-07-16 | 1988-11-25 | Erba Farmitalia | Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten |
| GB8612218D0 (en) * | 1986-05-20 | 1986-06-25 | Erba Farmitalia | Site specific alkylating agents |
-
1985
- 1985-06-08 CN CN198585103908A patent/CN85103908A/zh active Pending
- 1985-07-16 GB GB858517923A patent/GB8517923D0/en active Pending
- 1985-10-03 US US06/783,508 patent/US4738980A/en not_active Expired - Fee Related
-
1986
- 1986-07-11 SE SE8603099A patent/SE468594B/sv not_active IP Right Cessation
- 1986-07-11 AT AT0188786A patent/AT386822B/de not_active IP Right Cessation
- 1986-07-14 IE IE187486A patent/IE59275B1/en not_active IP Right Cessation
- 1986-07-14 NZ NZ216828A patent/NZ216828A/xx unknown
- 1986-07-14 NL NL8601838A patent/NL8601838A/xx not_active Application Discontinuation
- 1986-07-14 HU HU862903A patent/HU198087B/hu not_active IP Right Cessation
- 1986-07-14 IL IL79401A patent/IL79401A/xx not_active IP Right Cessation
- 1986-07-14 AU AU60203/86A patent/AU584723B2/en not_active Ceased
- 1986-07-14 ES ES8600291A patent/ES2000346A6/es not_active Expired
- 1986-07-15 GR GR861840A patent/GR861840B/el unknown
- 1986-07-15 DK DK335886A patent/DK335886A/da not_active Application Discontinuation
- 1986-07-15 PH PH34013A patent/PH23459A/en unknown
- 1986-07-15 SU SU864027842A patent/SU1535378A3/ru active
- 1986-07-15 NO NO862861A patent/NO169014C/no unknown
- 1986-07-15 CH CH2821/86A patent/CH671958A5/de not_active IP Right Cessation
- 1986-07-15 CA CA000513756A patent/CA1247627A/en not_active Expired
- 1986-07-15 FR FR868610295A patent/FR2585019B1/fr not_active Expired
- 1986-07-15 KR KR1019860005716A patent/KR940003495B1/ko not_active IP Right Cessation
- 1986-07-15 PT PT82985A patent/PT82985B/pt not_active IP Right Cessation
- 1986-07-15 BE BE0/216923A patent/BE905109A/fr not_active IP Right Cessation
- 1986-07-15 IT IT8621124A patent/IT1213103B/it active
- 1986-07-15 JP JP61164878A patent/JPH0780842B2/ja not_active Expired - Lifetime
- 1986-07-15 ZA ZA865262A patent/ZA865262B/xx unknown
- 1986-07-15 DE DE3623853A patent/DE3623853C2/de not_active Expired - Fee Related
- 1986-07-16 FI FI862960A patent/FI82929C/fi not_active IP Right Cessation
- 1986-07-16 CN CN86104774A patent/CN1026984C/zh not_active Expired - Fee Related
- 1986-07-16 GB GB8617293A patent/GB2178037B/en not_active Expired
- 1986-07-16 CZ CS865411A patent/CZ277823B6/cs unknown
-
1987
- 1987-11-11 SU SU874203631A patent/SU1538893A3/ru active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970716 |