FI862960A - Foerfarande foer framstaellning av distamycinderivat. - Google Patents

Foerfarande foer framstaellning av distamycinderivat. Download PDF

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Publication number
FI862960A
FI862960A FI862960A FI862960A FI862960A FI 862960 A FI862960 A FI 862960A FI 862960 A FI862960 A FI 862960A FI 862960 A FI862960 A FI 862960A FI 862960 A FI862960 A FI 862960A
Authority
FI
Finland
Prior art keywords
distamycinderivat
foerfarande foer
foer framstaellning
framstaellning
foerfarande
Prior art date
Application number
FI862960A
Other languages
English (en)
Other versions
FI862960A0 (fi
FI82929B (fi
FI82929C (fi
Inventor
Federico Arcamone
Nicola Mongelli
Fabio Animati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI862960A0 publication Critical patent/FI862960A0/fi
Publication of FI862960A publication Critical patent/FI862960A/fi
Publication of FI82929B publication Critical patent/FI82929B/fi
Application granted granted Critical
Publication of FI82929C publication Critical patent/FI82929C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI862960A 1985-07-16 1986-07-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara distamycinderivat. FI82929C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858517923A GB8517923D0 (en) 1985-07-16 1985-07-16 Distamycin derivatives
GB8517923 1985-07-16

Publications (4)

Publication Number Publication Date
FI862960A0 FI862960A0 (fi) 1986-07-16
FI862960A true FI862960A (fi) 1987-01-17
FI82929B FI82929B (fi) 1991-01-31
FI82929C FI82929C (fi) 1991-05-10

Family

ID=10582358

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862960A FI82929C (fi) 1985-07-16 1986-07-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara distamycinderivat.

Country Status (29)

Country Link
US (1) US4738980A (fi)
JP (1) JPH0780842B2 (fi)
KR (1) KR940003495B1 (fi)
CN (2) CN85103908A (fi)
AT (1) AT386822B (fi)
AU (1) AU584723B2 (fi)
BE (1) BE905109A (fi)
CA (1) CA1247627A (fi)
CH (1) CH671958A5 (fi)
CZ (1) CZ277823B6 (fi)
DE (1) DE3623853C2 (fi)
DK (1) DK335886A (fi)
ES (1) ES2000346A6 (fi)
FI (1) FI82929C (fi)
FR (1) FR2585019B1 (fi)
GB (2) GB8517923D0 (fi)
GR (1) GR861840B (fi)
HU (1) HU198087B (fi)
IE (1) IE59275B1 (fi)
IL (1) IL79401A (fi)
IT (1) IT1213103B (fi)
NL (1) NL8601838A (fi)
NO (1) NO169014C (fi)
NZ (1) NZ216828A (fi)
PH (1) PH23459A (fi)
PT (1) PT82985B (fi)
SE (1) SE468594B (fi)
SU (2) SU1535378A3 (fi)
ZA (1) ZA865262B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
US5049579A (en) * 1986-05-20 1991-09-17 Farmitalia Carlo Erba, S.R.L. Site specific alkylating agents
US5310752A (en) * 1986-05-20 1994-05-10 Farmitalia Carlo Erba Spa Site specific alkylating agents
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
WO1992013838A1 (en) * 1991-02-06 1992-08-20 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
DE4205948C2 (de) * 1992-02-24 1996-10-31 Mannesmann Ag Farbbandkassette für ein endloses Farbband
US5273991A (en) * 1992-07-29 1993-12-28 Research Corporation Technologies, Inc. Imidazole-containing compositions and methods of use thereof analogs of distamycin
US5637621A (en) * 1994-11-14 1997-06-10 Nzym, Inc. Methods and compositions for treating Botrytis infections
US5629348A (en) * 1994-11-14 1997-05-13 Nzym, Inc. Methods and compositions for treating septoria infections
EP0792262A2 (en) * 1994-11-14 1997-09-03 Nzym, Inc. Methods and compositions for treating phytopathogenic fungi infections
DE19805431A1 (de) * 1998-02-11 1999-08-12 Merck Patent Gmbh Heteroaromatische Oligoamide als Affinitätsliganden
US6555693B2 (en) 2000-03-16 2003-04-29 Genesoft, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7078536B2 (en) * 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
ITTO20010633A1 (it) * 2001-07-02 2003-01-02 Univ Ferrara Nuovo impiego di poliammidi eterocicliche e benzoeterocicliche strutturalmente correlate all'antibiotico naturale distamicina a.
DE60326735D1 (de) 2002-08-02 2009-04-30 Genesoft Pharmaceuticals Inc Biaryl-verbindungen mit antiinfektiver wirkung
US7265129B2 (en) * 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション （ピロールカルボキサミド）−（ベンズアミド）−（イミダゾールカルボキサミド）モチーフを有する抗菌化合物
US20070269420A1 (en) * 2003-11-24 2007-11-22 Chunduru Srinivas K Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases
KR102155411B1 (ko) * 2015-03-30 2020-09-11 메이지 세이카 파루마 가부시키가이샤 에피루비신 제조방법 및 그의 신규한 제조 중간체

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA557568A (en) * 1958-05-20 J. Weiss Martin Substituted aminopyrrolecarboxylic acids and esters
CA547128A (en) * 1957-10-08 W. Waller Coy Substituted pyrrolecarboxamidopyrroles
FR86210E (fi) * 1963-04-04 1966-03-23
BE666612A (fi) * 1963-07-26 1965-11-03
FR141F (fi) * 1963-07-26
BR6461040D0 (pt) * 1963-07-26 1973-08-02 Farmaceutici Italia Processo para preparar novos derivados de pirrol
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
NL130086C (fi) * 1964-07-14 1970-06-15
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
GB8612218D0 (en) * 1986-05-20 1986-06-25 Erba Farmitalia Site specific alkylating agents

Also Published As

Publication number Publication date
PT82985B (pt) 1989-01-30
DE3623853C2 (de) 1995-12-21
CS541186A3 (en) 1992-09-16
ATA188786A (de) 1988-03-15
ZA865262B (en) 1987-03-25
BE905109A (fr) 1987-01-15
NZ216828A (en) 1989-11-28
CH671958A5 (fi) 1989-10-13
US4738980A (en) 1988-04-19
NL8601838A (nl) 1987-02-16
SE8603099D0 (sv) 1986-07-11
IL79401A (en) 1991-05-12
CN86104774A (zh) 1987-02-11
HU198087B (en) 1989-07-28
AU584723B2 (en) 1989-06-01
KR940003495B1 (ko) 1994-04-23
JPS6230755A (ja) 1987-02-09
PT82985A (pt) 1986-08-01
GB2178037A (en) 1987-02-04
SE8603099L (sv) 1987-01-17
GB8617293D0 (en) 1986-08-20
AU6020386A (en) 1987-01-22
DE3623853A1 (de) 1987-01-29
PH23459A (en) 1989-08-07
CZ277823B6 (en) 1993-06-16
DK335886A (da) 1987-01-17
SE468594B (sv) 1993-02-15
JPH0780842B2 (ja) 1995-08-30
FI862960A0 (fi) 1986-07-16
FI82929B (fi) 1991-01-31
IL79401A0 (en) 1986-10-31
DK335886D0 (da) 1986-07-15
IE861874L (en) 1987-01-16
NO862861L (no) 1987-01-19
NO169014B (no) 1992-01-20
AT386822B (de) 1988-10-25
CN85103908A (zh) 1986-11-05
ES2000346A6 (es) 1988-02-16
HUT41814A (en) 1987-05-28
SU1535378A3 (ru) 1990-01-07
KR870001228A (ko) 1987-03-12
GB8517923D0 (en) 1985-08-21
FI82929C (fi) 1991-05-10
NO169014C (no) 1992-04-29
GB2178037B (en) 1989-07-26
NO862861D0 (no) 1986-07-15
IT1213103B (it) 1989-12-07
GR861840B (en) 1986-11-18
FR2585019B1 (fr) 1989-07-13
IE59275B1 (en) 1994-02-09
SU1538893A3 (ru) 1990-01-23
IT8621124A0 (it) 1986-07-15
FR2585019A1 (fr) 1987-01-23
CA1247627A (en) 1988-12-28
CN1026984C (zh) 1994-12-14

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Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: PHARMACIA & UPJOHN S.P.A.

MM Patent lapsed
MM Patent lapsed

Owner name: PHARMACIA & UPJOHN S., P.A.