ZA844767B - Novel beta-carbolines,their preparation and use as medicinal agents(s) - Google Patents

Novel beta-carbolines,their preparation and use as medicinal agents(s)

Info

Publication number
ZA844767B
ZA844767B ZA844767A ZA844767A ZA844767B ZA 844767 B ZA844767 B ZA 844767B ZA 844767 A ZA844767 A ZA 844767A ZA 844767 A ZA844767 A ZA 844767A ZA 844767 B ZA844767 B ZA 844767B
Authority
ZA
South Africa
Prior art keywords
alkyl
meaning
radical
image
denotes
Prior art date
Application number
ZA844767A
Other languages
English (en)
Inventor
Dieter Seidelmann
Andreas Huth
Claus Thyco Braestrup
Ralph Schmiechen
Dieter Rahtz
Mogens Engelstoft
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA844767B publication Critical patent/ZA844767B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Treating Waste Gases (AREA)
ZA844767A 1983-06-23 1984-06-22 Novel beta-carbolines,their preparation and use as medicinal agents(s) ZA844767B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833322895 DE3322895A1 (de) 1983-06-23 1983-06-23 Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)

Publications (1)

Publication Number Publication Date
ZA844767B true ZA844767B (en) 1985-02-27

Family

ID=6202362

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA844767A ZA844767B (en) 1983-06-23 1984-06-22 Novel beta-carbolines,their preparation and use as medicinal agents(s)

Country Status (17)

Country Link
US (1) US4894377A (hu)
EP (1) EP0130140B1 (hu)
JP (1) JPS6013790A (hu)
AT (1) ATE60332T1 (hu)
AU (1) AU575566B2 (hu)
CA (1) CA1254895A (hu)
DE (2) DE3322895A1 (hu)
DK (1) DK169785B1 (hu)
ES (1) ES533377A0 (hu)
FI (1) FI79109C (hu)
GR (1) GR82124B (hu)
HU (1) HU190573B (hu)
IE (1) IE57623B1 (hu)
IL (1) IL72165A (hu)
NO (1) NO160612C (hu)
SU (2) SU1376946A3 (hu)
ZA (1) ZA844767B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3240514A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung
DE3540654A1 (de) * 1985-11-13 1987-05-14 Schering Ag Phenoxy-substituierte ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3540653A1 (de) * 1985-11-13 1987-05-14 Schering Ag Neue 3-oxadiazol- und 3-carbonsaeure-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
US4952584A (en) * 1986-01-11 1990-08-28 Beecham Group P.L.C. 9H-pyrido[2,B-8]indole-3-carboxylic acid ester compounds having useful pharmaceutical activity
DE3609699A1 (de) * 1986-03-20 1987-09-24 Schering Ag 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
IL87563A (en) * 1987-08-28 1993-08-18 Schering Ag Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4029389A1 (de) * 1990-09-13 1992-03-26 Schering Ag Verfahren zur herstellung von (beta)-carbolin-derivaten
DE4109342A1 (de) * 1991-03-19 1992-09-24 Schering Ag Selektive phenylierung von 5-hydroxy-ss-carbolinderivaten
US5350750A (en) * 1991-04-27 1994-09-27 Schering Aktiengesellschaft β-carboline-3-hydroxyalkylcarboxylic acid ester derivatives, process for their production and their use in pharmaceutical agents
US5543519A (en) * 1991-06-15 1996-08-06 Schering Aktiengesellschaft 3-aryl or 3-hetaryl-β-carbolines, their production and use in pharmaceutical agents
DE4120109A1 (de) * 1991-06-15 1992-12-17 Schering Ag 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3023567A1 (de) * 1980-06-20 1982-01-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Substituierte (beta) -carbolin-3-carbonsaeurederivate
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3136857A1 (de) * 1981-09-14 1983-03-31 Schering Ag, 1000 Berlin Und 4619 Bergkamen Substituierte (beta)-carbolin-3-carbonsaeurealkylester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3048318A1 (de) * 1980-12-17 1982-07-22 Schering Ag, 1000 Berlin Und 4619 Bergkamen 4-alkoxyalkyl substituierte (beta)-carbolin-3-carbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DE3240514A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DK149270C (da) * 1983-05-27 1986-08-25 Schering Ag Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater

Also Published As

Publication number Publication date
EP0130140A3 (en) 1985-09-25
HUT34484A (en) 1985-03-28
ES8502998A1 (es) 1985-02-16
DK304484D0 (da) 1984-06-21
FI842499A0 (fi) 1984-06-20
FI842499A (fi) 1984-12-24
EP0130140B1 (de) 1991-01-23
ES533377A0 (es) 1985-02-16
SU1428202A3 (ru) 1988-09-30
JPS6013790A (ja) 1985-01-24
US4894377A (en) 1990-01-16
AU575566B2 (en) 1988-08-04
NO160612C (no) 1989-05-10
IE841573L (en) 1984-12-23
HU190573B (en) 1986-09-29
DK169785B1 (da) 1995-02-27
IE57623B1 (en) 1993-02-10
IL72165A0 (en) 1984-10-31
CA1254895A (en) 1989-05-30
NO842483L (no) 1984-12-27
FI79109C (fi) 1989-11-10
ATE60332T1 (de) 1991-02-15
FI79109B (fi) 1989-07-31
GR82124B (hu) 1984-12-13
AU2955284A (en) 1985-01-03
NO160612B (no) 1989-01-30
IL72165A (en) 1987-11-30
EP0130140A2 (de) 1985-01-02
SU1376946A3 (ru) 1988-02-23
DE3322895A1 (de) 1985-01-03
JPH0585552B2 (hu) 1993-12-07
DK304484A (da) 1984-12-24
DE3483980D1 (de) 1991-02-28

Similar Documents

Publication Publication Date Title
ZA844767B (en) Novel beta-carbolines,their preparation and use as medicinal agents(s)
DE3571322D1 (en) Bisacylphosphinoxides, their preparation and use
EA199800357A1 (ru) Фармацевтические ангиостатические дипептидные композиции и способы их применения
ES470155A1 (es) Un procedimiento para la obtencion de derivados de espiroa- mina
PT86225A (de) Neue diphosphonsaurederivate verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
ES8105969A1 (es) Procedimiento para preparar derivados fluorados de metil-be ta-alanina.
BE842440A (fr) Compositions analgesiques renfermant un derive de l'acide indole-3-acetique
ZA844782B (en) Novel beta-carbolines,a process for the preparation thereof and use as medicinal agents(h)
ES453162A1 (es) Un procedimiento para la obtencion de compuestos heteroci- clicos.
ES8304975A1 (es) "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES2104688T3 (es) Un procedimiento para la preparacion de un compuesto de tio-3-cefem 3-sustituido.
DK148804C (da) Fremgangsmaade til fremstilling af 1,2,3,4-tetrahydroquinolin-4-oner
ES8401456A1 (es) Procedimiento para la preparacion de 2-aminometilfenoles.
ATE16383T1 (de) Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
ATE18993T1 (de) Dibenzocycloheptenyliden-verbindungen zur verwendung bei der modulation der immunreaktion.
ES8308870A1 (es) Procedimiento para la preparacion de derivados de acido 5-(4-fenil-1-piperidinil) metil-2,3-dihidro-2-oxo-1h-imidazol-4-carboxilico.
DE3662099D1 (en) Saturated cycloalkylûc¨pyrrole-2(1h)-acetic acid amides and derivatives thereof
GB2001627A (en) alpha -Vinyl and ethynyl amino acid derivatives
DK0462556T3 (da) Hypotriglyceridæmisk anvendelse af bis(3,5-di-alkyl-4-hydroxyphenylthio)methaner
ES473636A1 (es) Un procedimiento para la preparacion de compuestos derivadosde lasalocida.
ES458203A1 (es) Procedimiento de obtencion de vincamina racemica desdoblableen susisomeros opticos.
ES367589A1 (es) Un procedimiento para la preparacion de un 2,3,5,9 b-tetra-hidro-5h-imidazo (2,i-a) isoindol-5-ol.
SU946176A1 (ru) Алкиловые эфиры 2,3,4,5-тетрабромкапроновой кислоты в качестве гербицидов