ES2104688T3 - Un procedimiento para la preparacion de un compuesto de tio-3-cefem 3-sustituido. - Google Patents
Un procedimiento para la preparacion de un compuesto de tio-3-cefem 3-sustituido.Info
- Publication number
- ES2104688T3 ES2104688T3 ES91900053T ES91900053T ES2104688T3 ES 2104688 T3 ES2104688 T3 ES 2104688T3 ES 91900053 T ES91900053 T ES 91900053T ES 91900053 T ES91900053 T ES 91900053T ES 2104688 T3 ES2104688 T3 ES 2104688T3
- Authority
- ES
- Spain
- Prior art keywords
- cefem
- tio
- procedure
- preparation
- substituted compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
SE PUEDE PRODUCIR UN ESTER DE 7 UIDO 5)$0 PREFERENCIAL, FACIL Y EFICAZMENTE HACIENDO REACCIONAR EL ESTER DE 7 ARBOXILICO CON LA FORMULA GENERAL *FIG* (EN DONDE R1 REPRESENTA ACILO, R REPRESENTA UN GRUPO PROTECTOR DEL GRUPO CARBOXILO Y R'' REPRESENTA ALQUILO INFERIOR O ARILO (NO)SUSTITUIDO) O UNA MEZCLA DE LOS MISMOS CON AMINOS SECUNDARIOS Y TERCIARIOS Y, ADEMAS, REACCIONANDO UNA SAL DE AMINO TERCIARIA DEL PRODUCTO DE REACCION CON UN COMPUESTO DE FORMULA GENERAL (4): R4 QUILO O METILO DE HETEROALQUILO SUSTITUIDO Y X REPRESENTA UN GRUPO DE SALIDA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1316424A JPH0686459B2 (ja) | 1989-12-07 | 1989-12-07 | 3―置換チオ―3―セフエム化合物の製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2104688T3 true ES2104688T3 (es) | 1997-10-16 |
Family
ID=18076928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91900053T Expired - Lifetime ES2104688T3 (es) | 1989-12-07 | 1990-12-07 | Un procedimiento para la preparacion de un compuesto de tio-3-cefem 3-sustituido. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5294705A (es) |
EP (1) | EP0504404B1 (es) |
JP (1) | JPH0686459B2 (es) |
DE (1) | DE69031222T2 (es) |
ES (1) | ES2104688T3 (es) |
WO (1) | WO1991009037A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL100576A (en) * | 1991-01-18 | 1995-11-27 | Eli Lilley And Company | Cephalosporin antibiotics |
TW427993B (en) * | 1993-09-09 | 2001-04-01 | Fujisawa Pharmaceutical Co | New cephem compounds |
US5698547A (en) * | 1994-04-01 | 1997-12-16 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
US5688786A (en) * | 1994-04-01 | 1997-11-18 | Microcide Pharmaceuticals, Inc. | β-lactam antibiotics |
US5593986A (en) * | 1994-04-01 | 1997-01-14 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
US5498777A (en) * | 1994-07-20 | 1996-03-12 | Merck & Co., Inc. | 3-thioheteroaryl cephalosporin compounds, compositions and methods of use |
AU4123396A (en) * | 1994-12-09 | 1996-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and pharmaceutical use thereof |
CA2461577A1 (en) * | 2001-11-12 | 2003-05-22 | Hans Rudolf Pfaendler | Novel c-3 s/o- and s/n formaldehe acetal derivatives of cephalosporins and their use as antibiotics |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH605997A5 (es) * | 1974-08-30 | 1978-10-13 | Ciba Geigy Ag | |
US3992377A (en) * | 1974-12-13 | 1976-11-16 | Eli Lilly And Company | 3-Thio-substituted cephalosporin antibiotics |
US4812562A (en) * | 1985-07-25 | 1989-03-14 | Taisho Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
JPS62267228A (ja) * | 1986-05-16 | 1987-11-19 | Kyowa Hakko Kogyo Co Ltd | 抗菌剤 |
DE3642450A1 (de) * | 1986-12-12 | 1988-06-23 | Bayer Ag | Substituierte benzamide |
JPH01128986A (ja) * | 1987-11-14 | 1989-05-22 | Banyu Pharmaceut Co Ltd | 3−ピリジニオアルキルチオセファロスポリン誘導体 |
-
1989
- 1989-12-07 JP JP1316424A patent/JPH0686459B2/ja not_active Expired - Fee Related
-
1990
- 1990-12-07 ES ES91900053T patent/ES2104688T3/es not_active Expired - Lifetime
- 1990-12-07 DE DE69031222T patent/DE69031222T2/de not_active Expired - Fee Related
- 1990-12-07 EP EP91900053A patent/EP0504404B1/en not_active Expired - Lifetime
- 1990-12-07 WO PCT/JP1990/001599 patent/WO1991009037A1/ja active IP Right Grant
- 1990-12-07 US US07/853,730 patent/US5294705A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1991009037A1 (en) | 1991-06-27 |
EP0504404A1 (en) | 1992-09-23 |
JPH0686459B2 (ja) | 1994-11-02 |
US5294705A (en) | 1994-03-15 |
DE69031222T2 (de) | 1997-12-11 |
JPH03178980A (ja) | 1991-08-02 |
EP0504404A4 (en) | 1993-03-10 |
EP0504404B1 (en) | 1997-08-06 |
DE69031222D1 (de) | 1997-09-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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