ES8304975A1 - "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos". - Google Patents

"procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".

Info

Publication number
ES8304975A1
ES8304975A1 ES513576A ES513576A ES8304975A1 ES 8304975 A1 ES8304975 A1 ES 8304975A1 ES 513576 A ES513576 A ES 513576A ES 513576 A ES513576 A ES 513576A ES 8304975 A1 ES8304975 A1 ES 8304975A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
thienyloxypropanol
amines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513576A
Other languages
English (en)
Other versions
ES513576A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES513576A0 publication Critical patent/ES513576A0/es
Publication of ES8304975A1 publication Critical patent/ES8304975A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS TRIPTAMINICOS SUSTITUIDOS DE TIENILOXIPROPANOLAMINAS, RACEMICOS Y OPTICAMENTE ACTIVOS Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R , R , R , R , R , R E Y PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA (III), EN LAS QUE W ES UN GRUPO REEMPLAZABLE POR SUSTITUCION NUCLEOFILICA, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE, TAL COMO METANOL, A LA TEMPERATURA DE REFLUJO DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS ~J-SIMPATOLITICOS Y VASODILATADORES.
ES513576A 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos". Expired ES8304975A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813119796 DE3119796A1 (de) 1981-05-19 1981-05-19 Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung

Publications (2)

Publication Number Publication Date
ES513576A0 ES513576A0 (es) 1983-03-16
ES8304975A1 true ES8304975A1 (es) 1983-03-16

Family

ID=6132635

Family Applications (5)

Application Number Title Priority Date Filing Date
ES512109A Expired ES8304122A1 (es) 1981-05-19 1982-05-12 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES513579A Granted ES513579A0 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES513578A Expired ES8304977A1 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES513576A Expired ES8304975A1 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES513577A Granted ES513577A0 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES512109A Expired ES8304122A1 (es) 1981-05-19 1982-05-12 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES513579A Granted ES513579A0 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".
ES513578A Expired ES8304977A1 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES513577A Granted ES513577A0 (es) 1981-05-19 1982-06-30 "procedimiento para la preparacion de derivados triptaminicos sustituidos de tieniloxipropanolaminas, racemicos y opticamente activos".

Country Status (12)

Country Link
EP (1) EP0065295A1 (es)
JP (1) JPS57193476A (es)
KR (1) KR830010110A (es)
AU (1) AU8378182A (es)
DE (1) DE3119796A1 (es)
DK (1) DK225382A (es)
ES (5) ES8304122A1 (es)
FI (1) FI821738A0 (es)
GR (1) GR76454B (es)
IL (1) IL65810A0 (es)
NO (1) NO821651L (es)
PT (1) PT74922B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703056A (en) * 1983-01-21 1987-10-27 Alkaloida Vegyeszeti Gyar New alkyl diamine derivatives
US4800211A (en) * 1986-08-18 1989-01-24 Merck & Co., Inc. 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
GB8708833D0 (en) * 1987-04-13 1987-05-20 Lilly S A E Organic compounds
GB8823041D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823040D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
GB8823042D0 (en) * 1988-09-30 1988-11-09 Lilly Sa Organic compounds & their use as pharmaceuticals
DE102008015032A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte Pyrazolamide und ihre Verwendung
DE102008015033A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062863A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062878A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte Furancarboxamide und ihre Verwendung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2720613A1 (de) * 1977-05-07 1978-11-16 Basf Ag Aminoderivate von substituierten hydroxy-thiophenen
CA1116598A (en) * 1977-07-13 1982-01-19 William T. Comer 3-indolyl-tertiary butylaminopropanols
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
FR2464952A1 (fr) * 1979-09-13 1981-03-20 Roussel Uclaf Nouveaux derives thienyliques, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
FI821738A0 (fi) 1982-05-17
ES8304978A1 (es) 1983-03-16
ES513579A0 (es) 1983-03-16
ES513578A0 (es) 1983-03-16
EP0065295A1 (de) 1982-11-24
PT74922A (de) 1982-06-01
DE3119796A1 (de) 1982-12-23
ES512109A0 (es) 1983-02-16
GR76454B (es) 1984-08-10
AU8378182A (en) 1982-11-25
PT74922B (de) 1984-11-26
ES513576A0 (es) 1983-03-16
KR830010110A (ko) 1983-12-26
IL65810A0 (en) 1982-08-31
NO821651L (no) 1982-11-22
JPS57193476A (en) 1982-11-27
ES8304122A1 (es) 1983-02-16
DK225382A (da) 1982-11-20
ES8304976A1 (es) 1983-03-16
ES8304977A1 (es) 1983-03-16
ES513577A0 (es) 1983-03-16

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