ZA201106618B - Modulators of cystic fibrosis transmembrane conductance regulator - Google Patents

Modulators of cystic fibrosis transmembrane conductance regulator

Info

Publication number
ZA201106618B
ZA201106618B ZA2011/06618A ZA201106618A ZA201106618B ZA 201106618 B ZA201106618 B ZA 201106618B ZA 2011/06618 A ZA2011/06618 A ZA 2011/06618A ZA 201106618 A ZA201106618 A ZA 201106618A ZA 201106618 B ZA201106618 B ZA 201106618B
Authority
ZA
South Africa
Prior art keywords
modulators
cystic fibrosis
fibrosis transmembrane
conductance regulator
transmembrane conductance
Prior art date
Application number
ZA2011/06618A
Other languages
English (en)
Inventor
Xiaoqing Yang
Ruah Sara S Hadida
Peter D J Grootenhuis
Goor Frederick F Van
Martyn C Botfield
Gregor Zlokarnik
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of ZA201106618B publication Critical patent/ZA201106618B/en

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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
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    • C—CHEMISTRY; METALLURGY
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    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
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ZA2011/06618A 2009-03-20 2011-09-09 Modulators of cystic fibrosis transmembrane conductance regulator ZA201106618B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16213009P 2009-03-20 2009-03-20
PCT/US2010/028062 WO2010108155A1 (en) 2009-03-20 2010-03-19 Modulators of cystic fibrosis transmembrane conductance regulator

Publications (1)

Publication Number Publication Date
ZA201106618B true ZA201106618B (en) 2012-11-28

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ZA2011/06618A ZA201106618B (en) 2009-03-20 2011-09-09 Modulators of cystic fibrosis transmembrane conductance regulator

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US (4) US8614325B2 (https=)
EP (1) EP2408749B1 (https=)
JP (3) JP5636418B2 (https=)
CN (1) CN102361856A (https=)
AU (1) AU2010226393B2 (https=)
BR (1) BRPI1012549B8 (https=)
CA (1) CA2755969C (https=)
CY (1) CY1120593T1 (https=)
DK (1) DK2408749T3 (https=)
ES (1) ES2683633T3 (https=)
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