ZA200606083B - Anti-epcam immunoglobulins - Google Patents

Anti-epcam immunoglobulins Download PDF

Info

Publication number
ZA200606083B
ZA200606083B ZA200606083A ZA200606083A ZA200606083B ZA 200606083 B ZA200606083 B ZA 200606083B ZA 200606083 A ZA200606083 A ZA 200606083A ZA 200606083 A ZA200606083 A ZA 200606083A ZA 200606083 B ZA200606083 B ZA 200606083B
Authority
ZA
South Africa
Prior art keywords
cancer
immunoglobulin
epcam
administration
serum
Prior art date
Application number
ZA200606083A
Other languages
English (en)
Inventor
Peters Malte
Locher Mathias
Prang Nadja
Quadt Cornelia
Original Assignee
Micromet Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromet Ag filed Critical Micromet Ag
Publication of ZA200606083B publication Critical patent/ZA200606083B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
ZA200606083A 2004-02-13 2006-07-21 Anti-epcam immunoglobulins ZA200606083B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/778,915 US20050180979A1 (en) 2004-02-13 2004-02-13 Anti-EpCAM immunoglobulins

Publications (1)

Publication Number Publication Date
ZA200606083B true ZA200606083B (en) 2007-10-31

Family

ID=34838270

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200606083A ZA200606083B (en) 2004-02-13 2006-07-21 Anti-epcam immunoglobulins

Country Status (23)

Country Link
US (3) US20050180979A1 (cg-RX-API-DMAC7.html)
EP (2) EP1713830B1 (cg-RX-API-DMAC7.html)
JP (1) JP5220315B2 (cg-RX-API-DMAC7.html)
KR (1) KR101236224B1 (cg-RX-API-DMAC7.html)
CN (1) CN1976951B (cg-RX-API-DMAC7.html)
AT (1) ATE437186T1 (cg-RX-API-DMAC7.html)
AU (1) AU2005215874B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0507660A (cg-RX-API-DMAC7.html)
CA (1) CA2555694C (cg-RX-API-DMAC7.html)
DE (1) DE602005015544D1 (cg-RX-API-DMAC7.html)
DK (1) DK1713830T3 (cg-RX-API-DMAC7.html)
EA (1) EA011951B1 (cg-RX-API-DMAC7.html)
ES (1) ES2328159T3 (cg-RX-API-DMAC7.html)
IL (1) IL177069A (cg-RX-API-DMAC7.html)
MX (1) MXPA06008942A (cg-RX-API-DMAC7.html)
NO (1) NO339364B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ549125A (cg-RX-API-DMAC7.html)
PL (1) PL1713830T3 (cg-RX-API-DMAC7.html)
PT (1) PT1713830E (cg-RX-API-DMAC7.html)
SI (1) SI1713830T1 (cg-RX-API-DMAC7.html)
UA (1) UA87128C2 (cg-RX-API-DMAC7.html)
WO (1) WO2005080428A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200606083B (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3351919A1 (en) 2003-01-24 2018-07-25 University of Utah Methods of predicting mortality risk by determining telomere length
WO2007008943A2 (en) 2005-07-08 2007-01-18 Xencor, Inc. Optimized anti-ep-cam antibodies
WO2007090670A1 (en) 2006-02-09 2007-08-16 Micromet Ag Treatment of metastatic breast cancer
US20100226922A1 (en) * 2006-06-08 2010-09-09 Dorothea Maetzel Specific protease inhibitors and their use in cancer therapy
EP1865001A1 (en) * 2006-06-08 2007-12-12 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Specific protease inhibitors and their use in cancer therapy
ATE512988T1 (de) 2007-04-04 2011-07-15 Sigma Tau Ind Farmaceuti Antikörper gegen epcam und anwendungen davon
EP2379747B1 (en) 2008-12-22 2013-07-03 University of Utah Research Foundation Monochrome multiplex quantitative pcr
CN102844443B (zh) * 2009-09-21 2014-08-06 保罗·沃尔菲什 用于甲状腺癌诊断和治疗的方法和组合物
JP6163502B2 (ja) * 2012-03-02 2017-07-12 アカデミア シニカAcademia Sinica 抗上皮細胞接着分子(EpCAM)抗体及びその使用方法
CN103409427B (zh) * 2012-09-24 2016-05-18 厦门大学 上皮细胞粘附分子的核酸适体EpCAM C及其制备方法
WO2014190138A2 (en) 2013-05-22 2014-11-27 Telomere Diagnostics, Inc. Measures of short telomere abundance
CN103275226B (zh) * 2013-06-09 2017-08-29 中国科学技术大学 特异性抗人上皮细胞粘附分子(EpCAM)的单克隆抗体的制备、鉴定及应用
PL3553087T3 (pl) * 2014-01-08 2025-04-28 The Board Of Trustees Of The Leland Stanford Junior University Terapia celowana nowotworu złośliwego płuc
JP2018501799A (ja) 2014-12-30 2018-01-25 テロメア ダイアグノスティクス インコーポレイテッド マルチプレックス定量的pcr
DK3377103T4 (en) * 2015-11-19 2025-05-19 Revitope Ltd Functional antibody fragment complementation for a two-components system for redirected killing of unwanted cells
CN110035768A (zh) 2016-07-26 2019-07-19 泰莎治疗私人有限公司 嵌合抗原受体
WO2020018964A1 (en) 2018-07-20 2020-01-23 Fred Hutchinson Cancer Research Center Compositions and methods for controlled expression of antigen-specific receptors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853697A (en) * 1995-10-25 1998-12-29 The United States Of America, As Represented By The Department Of Health & Human Services Methods of treating established colitis using antibodies against IL-12
ATE200679T1 (de) * 1997-04-14 2001-05-15 Micromet Ag Neues verfahren zur herstellung von anti-humanen antigenrezeptoren und deren verwendungen
US6855544B1 (en) * 1999-04-15 2005-02-15 Crucell Holland B.V. Recombinant protein production in a human cell
US7605238B2 (en) * 1999-08-24 2009-10-20 Medarex, Inc. Human CTLA-4 antibodies and their uses
CA2446087C (en) * 2001-05-03 2013-06-18 Stephen D. Gillies Recombinant tumor specific antibody and use thereof
US20030175268A1 (en) * 2002-01-11 2003-09-18 Saint-Remy Jean-Marie R. Method and pharmaceutical composition for preventing and/or treating systemic inflammatory response syndrome
CA2485691A1 (en) * 2002-05-20 2003-12-04 Abgenix, Inc. Treatment of renal carcinoma using antibodies against the egfr

Also Published As

Publication number Publication date
ATE437186T1 (de) 2009-08-15
WO2005080428A2 (en) 2005-09-01
EP2107071A3 (en) 2009-12-30
EA011951B1 (ru) 2009-06-30
BRPI0507660A (pt) 2007-07-17
SI1713830T1 (sl) 2009-10-31
US20120294873A1 (en) 2012-11-22
NO20064136L (no) 2006-11-07
US20070274982A1 (en) 2007-11-29
WO2005080428A3 (en) 2005-11-10
IL177069A0 (en) 2006-12-10
EP1713830B1 (en) 2009-07-22
EP2107071A2 (en) 2009-10-07
NO339364B1 (no) 2016-12-05
AU2005215874B2 (en) 2011-01-27
CA2555694A1 (en) 2005-09-01
KR101236224B1 (ko) 2013-02-22
AU2005215874A1 (en) 2005-09-01
EA200601386A1 (ru) 2007-06-29
UA87128C2 (ru) 2009-06-25
NZ549125A (en) 2008-09-26
JP2008500277A (ja) 2008-01-10
PL1713830T3 (pl) 2010-01-29
JP5220315B2 (ja) 2013-06-26
CA2555694C (en) 2013-04-16
ES2328159T3 (es) 2009-11-10
US20050180979A1 (en) 2005-08-18
IL177069A (en) 2010-11-30
KR20070009988A (ko) 2007-01-19
MXPA06008942A (es) 2007-01-26
CN1976951A (zh) 2007-06-06
PT1713830E (pt) 2009-10-19
HK1096103A1 (en) 2007-05-25
DE602005015544D1 (de) 2009-09-03
DK1713830T3 (da) 2009-10-12
CN1976951B (zh) 2012-03-14
EP1713830A2 (en) 2006-10-25

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