AU2005215874B2 - Anti-EpCAM immunoglobulins - Google Patents

Anti-EpCAM immunoglobulins Download PDF

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Publication number
AU2005215874B2
AU2005215874B2 AU2005215874A AU2005215874A AU2005215874B2 AU 2005215874 B2 AU2005215874 B2 AU 2005215874B2 AU 2005215874 A AU2005215874 A AU 2005215874A AU 2005215874 A AU2005215874 A AU 2005215874A AU 2005215874 B2 AU2005215874 B2 AU 2005215874B2
Authority
AU
Australia
Prior art keywords
cancer
immunoglobulin
epcam
administration
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005215874A
Other languages
English (en)
Other versions
AU2005215874A1 (en
Inventor
Mathias Locher
Malte Peters
Nadja Prang
Cornelia Quadt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Research Munich GmbH
Original Assignee
Amgen Research Munich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Research Munich GmbH filed Critical Amgen Research Munich GmbH
Publication of AU2005215874A1 publication Critical patent/AU2005215874A1/en
Application granted granted Critical
Publication of AU2005215874B2 publication Critical patent/AU2005215874B2/en
Assigned to AMGEN RESEARCH (MUNICH) GMBH reassignment AMGEN RESEARCH (MUNICH) GMBH Request to Amend Deed and Register Assignors: MICROMET AG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AU2005215874A 2004-02-13 2005-02-09 Anti-EpCAM immunoglobulins Ceased AU2005215874B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/778,915 2004-02-13
US10/778,915 US20050180979A1 (en) 2004-02-13 2004-02-13 Anti-EpCAM immunoglobulins
PCT/EP2005/001307 WO2005080428A2 (en) 2004-02-13 2005-02-09 Anti-epcam immunoglobulins

Publications (2)

Publication Number Publication Date
AU2005215874A1 AU2005215874A1 (en) 2005-09-01
AU2005215874B2 true AU2005215874B2 (en) 2011-01-27

Family

ID=34838270

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005215874A Ceased AU2005215874B2 (en) 2004-02-13 2005-02-09 Anti-EpCAM immunoglobulins

Country Status (23)

Country Link
US (3) US20050180979A1 (cg-RX-API-DMAC7.html)
EP (2) EP1713830B1 (cg-RX-API-DMAC7.html)
JP (1) JP5220315B2 (cg-RX-API-DMAC7.html)
KR (1) KR101236224B1 (cg-RX-API-DMAC7.html)
CN (1) CN1976951B (cg-RX-API-DMAC7.html)
AT (1) ATE437186T1 (cg-RX-API-DMAC7.html)
AU (1) AU2005215874B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0507660A (cg-RX-API-DMAC7.html)
CA (1) CA2555694C (cg-RX-API-DMAC7.html)
DE (1) DE602005015544D1 (cg-RX-API-DMAC7.html)
DK (1) DK1713830T3 (cg-RX-API-DMAC7.html)
EA (1) EA011951B1 (cg-RX-API-DMAC7.html)
ES (1) ES2328159T3 (cg-RX-API-DMAC7.html)
IL (1) IL177069A (cg-RX-API-DMAC7.html)
MX (1) MXPA06008942A (cg-RX-API-DMAC7.html)
NO (1) NO339364B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ549125A (cg-RX-API-DMAC7.html)
PL (1) PL1713830T3 (cg-RX-API-DMAC7.html)
PT (1) PT1713830E (cg-RX-API-DMAC7.html)
SI (1) SI1713830T1 (cg-RX-API-DMAC7.html)
UA (1) UA87128C2 (cg-RX-API-DMAC7.html)
WO (1) WO2005080428A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200606083B (cg-RX-API-DMAC7.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3351919A1 (en) 2003-01-24 2018-07-25 University of Utah Methods of predicting mortality risk by determining telomere length
WO2007008943A2 (en) 2005-07-08 2007-01-18 Xencor, Inc. Optimized anti-ep-cam antibodies
WO2007090670A1 (en) 2006-02-09 2007-08-16 Micromet Ag Treatment of metastatic breast cancer
US20100226922A1 (en) * 2006-06-08 2010-09-09 Dorothea Maetzel Specific protease inhibitors and their use in cancer therapy
EP1865001A1 (en) * 2006-06-08 2007-12-12 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Specific protease inhibitors and their use in cancer therapy
ATE512988T1 (de) 2007-04-04 2011-07-15 Sigma Tau Ind Farmaceuti Antikörper gegen epcam und anwendungen davon
EP2379747B1 (en) 2008-12-22 2013-07-03 University of Utah Research Foundation Monochrome multiplex quantitative pcr
CN102844443B (zh) * 2009-09-21 2014-08-06 保罗·沃尔菲什 用于甲状腺癌诊断和治疗的方法和组合物
JP6163502B2 (ja) * 2012-03-02 2017-07-12 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ 抗上皮細胞接着分子（ＥｐＣＡＭ）抗体及びその使用方法
CN103409427B (zh) * 2012-09-24 2016-05-18 厦门大学 上皮细胞粘附分子的核酸适体EpCAM C及其制备方法
WO2014190138A2 (en) 2013-05-22 2014-11-27 Telomere Diagnostics, Inc. Measures of short telomere abundance
CN103275226B (zh) * 2013-06-09 2017-08-29 中国科学技术大学 特异性抗人上皮细胞粘附分子（EpCAM）的单克隆抗体的制备、鉴定及应用
PL3553087T3 (pl) * 2014-01-08 2025-04-28 The Board Of Trustees Of The Leland Stanford Junior University Terapia celowana nowotworu złośliwego płuc
JP2018501799A (ja) 2014-12-30 2018-01-25 テロメア ダイアグノスティクス インコーポレイテッド マルチプレックス定量的ｐｃｒ
DK3377103T4 (en) * 2015-11-19 2025-05-19 Revitope Ltd Functional antibody fragment complementation for a two-components system for redirected killing of unwanted cells
CN110035768A (zh) 2016-07-26 2019-07-19 泰莎治疗私人有限公司 嵌合抗原受体
WO2020018964A1 (en) 2018-07-20 2020-01-23 Fred Hutchinson Cancer Research Center Compositions and methods for controlled expression of antigen-specific receptors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046645A2 (en) * 1997-04-14 1998-10-22 Micromet Gesellschaft Für Biomedizinische Forschung Mbh Method for the production of antihuman antigen receptors and uses thereof
US20030092160A1 (en) * 1999-04-15 2003-05-15 Abraham Bout Recombinant protein production in a human cell

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853697A (en) * 1995-10-25 1998-12-29 The United States Of America, As Represented By The Department Of Health & Human Services Methods of treating established colitis using antibodies against IL-12
US7605238B2 (en) * 1999-08-24 2009-10-20 Medarex, Inc. Human CTLA-4 antibodies and their uses
CA2446087C (en) * 2001-05-03 2013-06-18 Stephen D. Gillies Recombinant tumor specific antibody and use thereof
US20030175268A1 (en) * 2002-01-11 2003-09-18 Saint-Remy Jean-Marie R. Method and pharmaceutical composition for preventing and/or treating systemic inflammatory response syndrome
CA2485691A1 (en) * 2002-05-20 2003-12-04 Abgenix, Inc. Treatment of renal carcinoma using antibodies against the egfr

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998046645A2 (en) * 1997-04-14 1998-10-22 Micromet Gesellschaft Für Biomedizinische Forschung Mbh Method for the production of antihuman antigen receptors and uses thereof
US20030092160A1 (en) * 1999-04-15 2003-05-15 Abraham Bout Recombinant protein production in a human cell

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Lewis et al. Current Opinion in Molecular Therapeutics 2003, 5(4), 433-436 *

Also Published As

Publication number Publication date
ATE437186T1 (de) 2009-08-15
WO2005080428A2 (en) 2005-09-01
EP2107071A3 (en) 2009-12-30
EA011951B1 (ru) 2009-06-30
BRPI0507660A (pt) 2007-07-17
SI1713830T1 (sl) 2009-10-31
US20120294873A1 (en) 2012-11-22
NO20064136L (no) 2006-11-07
US20070274982A1 (en) 2007-11-29
WO2005080428A3 (en) 2005-11-10
ZA200606083B (en) 2007-10-31
IL177069A0 (en) 2006-12-10
EP1713830B1 (en) 2009-07-22
EP2107071A2 (en) 2009-10-07
NO339364B1 (no) 2016-12-05
CA2555694A1 (en) 2005-09-01
KR101236224B1 (ko) 2013-02-22
AU2005215874A1 (en) 2005-09-01
EA200601386A1 (ru) 2007-06-29
UA87128C2 (ru) 2009-06-25
NZ549125A (en) 2008-09-26
JP2008500277A (ja) 2008-01-10
PL1713830T3 (pl) 2010-01-29
JP5220315B2 (ja) 2013-06-26
CA2555694C (en) 2013-04-16
ES2328159T3 (es) 2009-11-10
US20050180979A1 (en) 2005-08-18
IL177069A (en) 2010-11-30
KR20070009988A (ko) 2007-01-19
MXPA06008942A (es) 2007-01-26
CN1976951A (zh) 2007-06-06
PT1713830E (pt) 2009-10-19
HK1096103A1 (en) 2007-05-25
DE602005015544D1 (de) 2009-09-03
DK1713830T3 (da) 2009-10-12
CN1976951B (zh) 2012-03-14
EP1713830A2 (en) 2006-10-25

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE PATENTEE TO READ AMGEN RESEARCH (MUNICH) GMBH .

MK14 Patent ceased section 143(a) (annual fees not paid) or expired