ZA200501913B - New compounds for the inhibition of rotamases and use thereof - Google Patents

New compounds for the inhibition of rotamases and use thereof

Info

Publication number
ZA200501913B
ZA200501913B ZA2005/01913A ZA200501913A ZA200501913B ZA 200501913 B ZA200501913 B ZA 200501913B ZA 2005/01913 A ZA2005/01913 A ZA 2005/01913A ZA 200501913 A ZA200501913 A ZA 200501913A ZA 200501913 B ZA200501913 B ZA 200501913B
Authority
ZA
South Africa
Prior art keywords
rotamases
inhibition
new compounds
compounds
new
Prior art date
Application number
ZA2005/01913A
Other languages
English (en)
Inventor
Jochen Knolle
Mike Schutkowski
Gerd Hummel
Thomas Tradler
Frank Osterkamp
Christoph Gibson
Laurence Jobron
Claudia Christner
Dirk Scharn
Roland Stragies
Original Assignee
Jerini Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jerini Ag filed Critical Jerini Ag
Publication of ZA200501913B publication Critical patent/ZA200501913B/en

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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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ZA2005/01913A 2002-09-18 2005-03-07 New compounds for the inhibition of rotamases and use thereof ZA200501913B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20020020987 EP1402888A1 (en) 2002-09-18 2002-09-18 The use of substituted carbocyclic compounds as rotamases inhibitors
PCT/EP2003/010406 WO2004026815A2 (en) 2002-09-18 2003-09-18 Phenol derivatives and their use as rotamase inhibitors

Publications (1)

Publication Number Publication Date
ZA200501913B true ZA200501913B (en) 2005-07-27

Family

ID=31970282

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2005/01913A ZA200501913B (en) 2002-09-18 2005-03-07 New compounds for the inhibition of rotamases and use thereof

Country Status (14)

Country Link
US (2) US20070054904A1 (enExample)
EP (3) EP1402888A1 (enExample)
JP (2) JP2005539072A (enExample)
KR (1) KR20050053673A (enExample)
CN (1) CN100546977C (enExample)
AU (1) AU2003271619A1 (enExample)
BR (1) BR0314544A (enExample)
CA (1) CA2498662A1 (enExample)
MX (1) MXPA05003084A (enExample)
PL (1) PL374846A1 (enExample)
RU (2) RU2005111256A (enExample)
SG (1) SG165995A1 (enExample)
WO (1) WO2004026815A2 (enExample)
ZA (1) ZA200501913B (enExample)

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AU2004303461B2 (en) * 2003-12-23 2011-04-28 H. Lundbeck A/S 2-(1H-indolylsulfanyl)-benzyl amine derivatives as SSRI
EP1713780B1 (en) * 2004-02-05 2012-01-18 Probiodrug AG Novel inhibitors of glutaminyl cyclase
CA2559665A1 (en) 2004-03-16 2005-09-29 The Regents Of The University Of California Reducing nephropathy with inhibitors of soluble epoxide hydrolase and epoxyeicosanoids
KR20070011475A (ko) * 2004-05-12 2007-01-24 쉐링 코포레이션 Ｃｘｃｒ1 및 ｃｘｃｒ2 케모카인 길항제
US7550499B2 (en) 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
CN101084216B (zh) 2004-10-20 2011-09-14 加利福尼亚大学董事会 可溶性环氧化物水解酶的改进抑制剂
AU2006206611A1 (en) 2005-01-19 2006-07-27 Bristol-Myers Squibb Company 2-phenoxy-N- (1, 3 , 4-thiadizol-2-yl) pyridin-3-amine derivatives and related compounds as P2Y1 receptor inhibitors for the treatment of thromboembolic disorders
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