ZA200500065B - Crystalline 2,5,-dione-3-(1-methyl-1H-indol-3-yl)-Ä1-(pyridin-2-ylmethyl)piperidin-4-ylÜ-1H-indol-3-ylÜ-1H-pyrrole mono-hydrochloride - Google Patents

Crystalline 2,5,-dione-3-(1-methyl-1H-indol-3-yl)-Ä1-(pyridin-2-ylmethyl)piperidin-4-ylÜ-1H-indol-3-ylÜ-1H-pyrrole mono-hydrochloride

Info

Publication number
ZA200500065B
ZA200500065B ZA200500065A ZA200500065A ZA200500065B ZA 200500065 B ZA200500065 B ZA 200500065B ZA 200500065 A ZA200500065 A ZA 200500065A ZA 200500065 A ZA200500065 A ZA 200500065A ZA 200500065 B ZA200500065 B ZA 200500065B
Authority
ZA
South Africa
Prior art keywords
ylü
indol
piperidin
ylmethyl
dione
Prior art date
Application number
ZA200500065A
Other languages
English (en)
Inventor
Julie K Bush
Susan M Reutzel-Edens
Margaret M Faul
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42799191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200500065(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA200500065B publication Critical patent/ZA200500065B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200500065A 2002-07-12 2006-01-04 Crystalline 2,5,-dione-3-(1-methyl-1H-indol-3-yl)-Ä1-(pyridin-2-ylmethyl)piperidin-4-ylÜ-1H-indol-3-ylÜ-1H-pyrrole mono-hydrochloride ZA200500065B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39597602P 2002-07-12 2002-07-12

Publications (1)

Publication Number Publication Date
ZA200500065B true ZA200500065B (en) 2006-03-29

Family

ID=42799191

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200500065A ZA200500065B (en) 2002-07-12 2006-01-04 Crystalline 2,5,-dione-3-(1-methyl-1H-indol-3-yl)-Ä1-(pyridin-2-ylmethyl)piperidin-4-ylÜ-1H-indol-3-ylÜ-1H-pyrrole mono-hydrochloride

Country Status (21)

Country Link
US (2) US8114901B2 (https=)
EP (1) EP1523313B1 (https=)
JP (2) JP4771356B2 (https=)
KR (1) KR100687165B1 (https=)
CN (1) CN100430058C (https=)
AU (1) AU2003280958B9 (https=)
CA (1) CA2393720C (https=)
DE (1) DE60317675T2 (https=)
EA (1) EA007463B1 (https=)
EC (1) ECSP055537A (https=)
ES (1) ES2295605T3 (https=)
HR (1) HRP20050035B1 (https=)
IL (1) IL165747A (https=)
NO (1) NO330254B1 (https=)
NZ (1) NZ537137A (https=)
PE (1) PE20040652A1 (https=)
PL (1) PL373046A1 (https=)
TW (1) TWI315667B (https=)
UA (1) UA78801C2 (https=)
WO (1) WO2004006928A1 (https=)
ZA (1) ZA200500065B (https=)

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CN101146532B (zh) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 药物化合物
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
WO2010101626A1 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Techniques and devices associated with blood sampling
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
MX339926B (es) * 2010-09-30 2016-06-16 Wisconsin Alumni Res Found * (20r, 25s)-metilen-19,26-dinor-1a,25-dihidroxivitamina d3 en forma cristalina.
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
JP6121400B2 (ja) 2011-04-29 2017-04-26 セブンス センス バイオシステムズ，インコーポレーテッド 流体の送達および／または受け取り
CN109952341A (zh) 2016-06-17 2019-06-28 洛斯安第斯大学 衍生自天然来源的冷适应海洋物种的明胶聚合物及其用途
BR112019002007B1 (pt) 2016-08-10 2024-01-16 F. Hoffmann-La Roche Ag Composição farmacêutica e uso de uma composição farmacêutica
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين
CN116199590B (zh) * 2022-12-26 2024-12-24 湖北美林药业有限公司 一种盐酸多巴酚丁胺及其注射剂

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US4808613A (en) * 1986-11-21 1989-02-28 Bristol-Myers Company Rebeccamycin derivative containing pharmaceutical composition
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
DE3803620A1 (de) 1988-02-06 1989-08-17 Goedecke Ag Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
NZ227850A (en) * 1988-02-10 1991-11-26 Hoffmann La Roche Indole substituted pyrrole derivatives; preparatory process and medicaments for use against inflammatory immunological, bronchopulmonary or vascular disorders
GB8904161D0 (en) * 1989-02-23 1989-04-05 Hoffmann La Roche Substituted pyrroles
US5380746A (en) * 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
CA2015996C (en) 1989-05-05 2001-08-28 Hartmut Osswald Bis-(1h-indol-3-yl)-maleinimide derivatives and their use as pharmaceuticals
US5489608A (en) * 1989-12-21 1996-02-06 Goedecke Aktiengesellschaft Indolocarbazole derivatives and the use thereof
DE4005969A1 (de) 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4005970A1 (de) 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte maleinimide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
CA2046801C (en) 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles
US5292747A (en) * 1990-08-07 1994-03-08 Hoffman-La Roche Inc. Substituted pyrroles
GB9123396D0 (en) 1991-11-04 1991-12-18 Hoffmann La Roche A process for the manufacture of substituted maleimides
US5461146A (en) 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
DE4243321A1 (de) 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
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SE501711C2 (sv) * 1993-09-08 1995-05-02 Jimek Int Ab Sprayrör för en duktvättanordning vid en tryckpress
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
CA2179650C (en) * 1993-12-23 2007-10-30 William Francis Heath, Jr. Bisindolemaleimides and their use as protein kinase c inhibitors
US5545636A (en) * 1993-12-23 1996-08-13 Eli Lilly And Company Protein kinase C inhibitors
US5481003A (en) * 1994-06-22 1996-01-02 Eli Lilly And Company Protein kinase C inhibitors
PE91598A1 (es) * 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
GB9620390D0 (en) * 1996-09-30 1996-11-13 Eisai London Res Lab Ltd Substances and their uses
AU6335600A (en) * 1999-07-29 2001-02-19 Eli Lilly And Company A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride
WO2001030331A2 (en) * 1999-10-22 2001-05-03 Eli Lilly And Company Therapeutic compositions including protein kinase c inhibitors
WO2002002116A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Therapeutic treatment of cancer with a protein kinase c inhibitor
AU2001271257A1 (en) * 2000-06-29 2002-01-14 Eli Lilly And Company Use of a protein kinase c inhibitor to enhance the clinical efficacy of anti-neoplastic chemotherapeutic agents and radiation therapy
EP1513830A1 (en) * 2002-06-05 2005-03-16 Janssen Pharmaceutica N.V. Bisindolyl-maleimid derivatives as kinase inhibitors

Also Published As

Publication number Publication date
PL373046A1 (en) 2005-08-08
KR100687165B1 (ko) 2007-02-27
JP2011144182A (ja) 2011-07-28
AU2003280958B2 (en) 2008-12-18
US20050288332A1 (en) 2005-12-29
NO20050676L (no) 2005-02-09
HK1075839A1 (en) 2005-12-30
ECSP055537A (es) 2005-03-10
JP4771356B2 (ja) 2011-09-14
JP5242718B2 (ja) 2013-07-24
CN1668304A (zh) 2005-09-14
ES2295605T3 (es) 2008-04-16
HRP20050035B1 (hr) 2013-07-31
NO330254B1 (no) 2011-03-14
CA2393720C (en) 2010-09-14
US20070270465A1 (en) 2007-11-22
KR20050021453A (ko) 2005-03-07
TWI315667B (en) 2009-10-11
DE60317675D1 (de) 2008-01-03
AU2003280958B9 (en) 2009-07-02
EP1523313B1 (en) 2007-11-21
HRP20050035A2 (en) 2005-04-30
EA200500191A1 (ru) 2005-06-30
NZ537137A (en) 2007-11-30
CA2393720A1 (en) 2004-01-16
WO2004006928A1 (en) 2004-01-22
IL165747A (en) 2010-05-17
DE60317675T2 (de) 2008-10-30
AU2003280958B8 (en) 2009-02-19
AU2003280958A1 (en) 2004-02-02
EP1523313A1 (en) 2005-04-20
UA78801C2 (en) 2007-04-25
TW200408392A (en) 2004-06-01
IL165747A0 (en) 2006-01-15
EA007463B1 (ru) 2006-10-27
PE20040652A1 (es) 2004-10-05
US8114901B2 (en) 2012-02-14
JP2006502115A (ja) 2006-01-19
CN100430058C (zh) 2008-11-05

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