HRP20050035B1 - Kristalniäśni 2,5-dion-3-(1-metil-1h-indol-3-il)-4-[1-(piridin-2-ilmetil)piperidin-4-il]-1h-indol-3-il]-1h-pirol monohidroklorid - Google Patents

Kristalniäśni 2,5-dion-3-(1-metil-1h-indol-3-il)-4-[1-(piridin-2-ilmetil)piperidin-4-il]-1h-indol-3-il]-1h-pirol monohidroklorid

Info

Publication number
HRP20050035B1
HRP20050035B1 HRP20050035AA HRP20050035A HRP20050035B1 HR P20050035 B1 HRP20050035 B1 HR P20050035B1 HR P20050035A A HRP20050035A A HR P20050035AA HR P20050035 A HRP20050035 A HR P20050035A HR P20050035 B1 HRP20050035 B1 HR P20050035B1
Authority
HR
Croatia
Prior art keywords
indol
piperidin
ylmethyl
dione
pyridin
Prior art date
Application number
HRP20050035AA
Other languages
English (en)
Inventor
Julie Kay Bush
Margaret Mary Ful
Susan Marie Reutzel-Edens
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42799191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20050035(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of HRP20050035A2 publication Critical patent/HRP20050035A2/hr
Publication of HRP20050035B1 publication Critical patent/HRP20050035B1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Opisani izum se odnosi na kristalinični 2,5-dion-3-(1-metil-1H-indol-3-il)-4-[1-(piridin-2-ilmetil)piperidin-4-il]-1H-indol-3-il]-1H-pirol monohidroklorid, farmaceutsku formulaciju koja sadrži spomenutu sol i na postupke liječenja raka te inhibiranje rasta tumora korištenjem spomenute soli.
HRP20050035AA 2002-07-12 2005-01-12 Kristalniäśni 2,5-dion-3-(1-metil-1h-indol-3-il)-4-[1-(piridin-2-ilmetil)piperidin-4-il]-1h-indol-3-il]-1h-pirol monohidroklorid HRP20050035B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39597602P 2002-07-12 2002-07-12
PCT/US2003/019548 WO2004006928A1 (en) 2002-07-12 2003-07-08 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride

Publications (2)

Publication Number Publication Date
HRP20050035A2 HRP20050035A2 (en) 2005-04-30
HRP20050035B1 true HRP20050035B1 (hr) 2013-07-31

Family

ID=42799191

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20050035AA HRP20050035B1 (hr) 2002-07-12 2005-01-12 Kristalniäśni 2,5-dion-3-(1-metil-1h-indol-3-il)-4-[1-(piridin-2-ilmetil)piperidin-4-il]-1h-indol-3-il]-1h-pirol monohidroklorid

Country Status (22)

Country Link
US (2) US8114901B2 (hr)
EP (1) EP1523313B1 (hr)
JP (2) JP4771356B2 (hr)
KR (1) KR100687165B1 (hr)
CN (1) CN100430058C (hr)
AU (1) AU2003280958B9 (hr)
CA (1) CA2393720C (hr)
DE (1) DE60317675T2 (hr)
EA (1) EA007463B1 (hr)
EC (1) ECSP055537A (hr)
ES (1) ES2295605T3 (hr)
HK (1) HK1075839A1 (hr)
HR (1) HRP20050035B1 (hr)
IL (1) IL165747A (hr)
NO (1) NO330254B1 (hr)
NZ (1) NZ537137A (hr)
PE (1) PE20040652A1 (hr)
PL (1) PL373046A1 (hr)
TW (1) TWI315667B (hr)
UA (1) UA78801C2 (hr)
WO (1) WO2004006928A1 (hr)
ZA (1) ZA200500065B (hr)

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KR101345002B1 (ko) 2005-01-21 2013-12-31 아스텍스 테라퓨틱스 리미티드 제약 화합물
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
WO2010101620A2 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
CN103068308B (zh) 2010-07-16 2016-03-16 第七感生物系统有限公司 用于流体传输装置的低压环境
AU2011308911B2 (en) * 2010-09-30 2014-10-02 Wisconsin Alumni Research Foundation (20R,25S)-2-methylene-19,26-dinor-1alpha, 25-dihydroxyvitamin D3 in crystalline form
CN103370007B (zh) 2010-11-09 2018-12-18 第七感生物系统有限公司 用于采血的系统和界面
EP2701598A1 (en) 2011-04-29 2014-03-05 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
ES2597081T3 (es) 2011-04-29 2017-01-13 Seventh Sense Biosystems, Inc. Entrega y/o recepción de fluidos
KR20190086655A (ko) 2016-06-17 2019-07-23 유니버시다드 데 로스 안데스 저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도
BR112019002007B1 (pt) 2016-08-10 2024-01-16 F. Hoffmann-La Roche Ag Composição farmacêutica e uso de uma composição farmacêutica
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين

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WO2001030331A2 (en) * 1999-10-22 2001-05-03 Eli Lilly And Company Therapeutic compositions including protein kinase c inhibitors
WO2002002116A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Therapeutic treatment of cancer with a protein kinase c inhibitor
WO2002002094A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Use of a protein kinase c inhibitor to enhance the clinical efficacy of anti-neoplastic chemotherapeutic agents and radiation therapy

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US4808613A (en) 1986-11-21 1989-02-28 Bristol-Myers Company Rebeccamycin derivative containing pharmaceutical composition
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WO1995017182A1 (en) * 1993-12-23 1995-06-29 Eli Lilly And Company Protein kinase c inhibitors
WO2001030331A2 (en) * 1999-10-22 2001-05-03 Eli Lilly And Company Therapeutic compositions including protein kinase c inhibitors
WO2002002116A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Therapeutic treatment of cancer with a protein kinase c inhibitor
WO2002002094A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Use of a protein kinase c inhibitor to enhance the clinical efficacy of anti-neoplastic chemotherapeutic agents and radiation therapy

Also Published As

Publication number Publication date
ECSP055537A (es) 2005-03-10
HK1075839A1 (en) 2005-12-30
CN100430058C (zh) 2008-11-05
IL165747A0 (en) 2006-01-15
CA2393720A1 (en) 2004-01-16
KR20050021453A (ko) 2005-03-07
JP5242718B2 (ja) 2013-07-24
TW200408392A (en) 2004-06-01
DE60317675D1 (de) 2008-01-03
AU2003280958B9 (en) 2009-07-02
AU2003280958A1 (en) 2004-02-02
NO20050676L (no) 2005-02-09
AU2003280958B8 (en) 2009-02-19
US8114901B2 (en) 2012-02-14
EP1523313A1 (en) 2005-04-20
EP1523313B1 (en) 2007-11-21
DE60317675T2 (de) 2008-10-30
PL373046A1 (en) 2005-08-08
NO330254B1 (no) 2011-03-14
UA78801C2 (en) 2007-04-25
CA2393720C (en) 2010-09-14
US20050288332A1 (en) 2005-12-29
JP2006502115A (ja) 2006-01-19
TWI315667B (en) 2009-10-11
JP4771356B2 (ja) 2011-09-14
CN1668304A (zh) 2005-09-14
ZA200500065B (en) 2006-03-29
NZ537137A (en) 2007-11-30
WO2004006928A1 (en) 2004-01-22
JP2011144182A (ja) 2011-07-28
PE20040652A1 (es) 2004-10-05
HRP20050035A2 (en) 2005-04-30
EA007463B1 (ru) 2006-10-27
US20070270465A1 (en) 2007-11-22
ES2295605T3 (es) 2008-04-16
IL165747A (en) 2010-05-17
KR100687165B1 (ko) 2007-02-27
EA200500191A1 (ru) 2005-06-30
AU2003280958B2 (en) 2008-12-18

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