ZA200201188B - Drug delivery device. - Google Patents
Drug delivery device. Download PDFInfo
- Publication number
- ZA200201188B ZA200201188B ZA200201188A ZA200201188A ZA200201188B ZA 200201188 B ZA200201188 B ZA 200201188B ZA 200201188 A ZA200201188 A ZA 200201188A ZA 200201188 A ZA200201188 A ZA 200201188A ZA 200201188 B ZA200201188 B ZA 200201188B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutically active
- active agent
- well
- drug delivery
- inner core
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title claims description 33
- 239000013543 active substance Substances 0.000 claims description 82
- 210000003786 sclera Anatomy 0.000 claims description 35
- 239000003732 agents acting on the eye Substances 0.000 claims description 18
- 229940023490 ophthalmic product Drugs 0.000 claims description 18
- 239000000017 hydrogel Substances 0.000 claims description 11
- 150000001875 compounds Chemical class 0.000 claims description 4
- GGUSQTSTQSHJAH-UHFFFAOYSA-N 1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol Chemical compound C=1C=C(Cl)C=CC=1C(O)CN(CC1)CCC1CC1=CC=C(F)C=C1 GGUSQTSTQSHJAH-UHFFFAOYSA-N 0.000 claims description 2
- 229950005455 eliprodil Drugs 0.000 claims description 2
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- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
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- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 2
- 238000001721 transfer moulding Methods 0.000 description 2
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
- A61F2009/00891—Glaucoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16067399P | 1999-10-21 | 1999-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200201188B true ZA200201188B (en) | 2003-04-30 |
Family
ID=22577913
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200201189A ZA200201189B (en) | 1999-10-21 | 2002-02-12 | Ophthalmic drug delivery device. |
ZA200201188A ZA200201188B (en) | 1999-10-21 | 2002-02-12 | Drug delivery device. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200201189A ZA200201189B (en) | 1999-10-21 | 2002-02-12 | Ophthalmic drug delivery device. |
Country Status (22)
Country | Link |
---|---|
US (3) | US6413540B1 (pl) |
EP (2) | EP1221917B1 (pl) |
JP (1) | JP4837861B2 (pl) |
KR (1) | KR100732262B1 (pl) |
CN (1) | CN1292721C (pl) |
AR (3) | AR026165A1 (pl) |
AT (2) | ATE414494T1 (pl) |
AU (2) | AU768400B2 (pl) |
BR (1) | BR0014929B1 (pl) |
CA (1) | CA2383499C (pl) |
CY (1) | CY1109489T1 (pl) |
DE (2) | DE60040876D1 (pl) |
DK (1) | DK1473003T3 (pl) |
ES (2) | ES2315598T3 (pl) |
HK (2) | HK1048427B (pl) |
MX (1) | MXPA02002338A (pl) |
PL (1) | PL196988B1 (pl) |
PT (2) | PT1221917E (pl) |
TR (1) | TR200201047T2 (pl) |
TW (1) | TW555575B (pl) |
WO (1) | WO2001028472A1 (pl) |
ZA (2) | ZA200201189B (pl) |
Families Citing this family (182)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1104302A4 (en) * | 1998-07-10 | 2006-08-09 | Retmed Pty Ltd | PROPHYLACTIC TREATMENTS OF BLOOD VESSEL NEOFORMATION IN MACULAR DEGENERATION |
AU772917B2 (en) | 1999-04-26 | 2004-05-13 | Gmp Vision Solutions, Inc. | Stent device and method for treating glaucoma |
US7943162B2 (en) | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
US6416777B1 (en) * | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
ATE414494T1 (de) * | 1999-10-21 | 2008-12-15 | Alcon Inc | Medikamentenzuführeinrichtung |
US20050119737A1 (en) * | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
US7867186B2 (en) | 2002-04-08 | 2011-01-11 | Glaukos Corporation | Devices and methods for treatment of ocular disorders |
US20020143284A1 (en) * | 2001-04-03 | 2002-10-03 | Hosheng Tu | Drug-releasing trabecular implant for glaucoma treatment |
US6638239B1 (en) | 2000-04-14 | 2003-10-28 | Glaukos Corporation | Apparatus and method for treating glaucoma |
US7708711B2 (en) | 2000-04-14 | 2010-05-04 | Glaukos Corporation | Ocular implant with therapeutic agents and methods thereof |
AR030345A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
US6756049B2 (en) * | 2000-12-29 | 2004-06-29 | Bausch & Lomb Incorporated | Sustained release drug delivery devices |
EP1347742A1 (en) * | 2001-01-03 | 2003-10-01 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with prefabricated permeable plugs |
JP4184082B2 (ja) | 2001-01-03 | 2008-11-19 | ボシュ・アンド・ロム・インコーポレイテッド | 複数の薬剤を備えた徐放薬剤送達装置 |
WO2002058667A2 (en) * | 2001-01-26 | 2002-08-01 | Bausch & Lomb Incorporated | Improved process for the production of sustained release drug delivery devices |
AU2002258754B2 (en) | 2001-04-07 | 2006-08-17 | Glaukos Corporation | Glaucoma stent and methods thereof for glaucoma treatment |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
US7488303B1 (en) * | 2002-09-21 | 2009-02-10 | Glaukos Corporation | Ocular implant with anchor and multiple openings |
US7678065B2 (en) | 2001-05-02 | 2010-03-16 | Glaukos Corporation | Implant with intraocular pressure sensor for glaucoma treatment |
WO2002089767A1 (en) * | 2001-05-03 | 2002-11-14 | Massachusetts Eye And Ear Infirmary | Implantable drug delivery device and use thereof |
WO2002089699A2 (en) | 2001-05-03 | 2002-11-14 | Glaukos Corporation | Medical device and methods of use for glaucoma treatment |
EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
ES2271301T3 (es) * | 2001-07-23 | 2007-04-16 | Alcon, Inc. | Dispositivo de suministro de farmaco oftalmico. |
CA2447802C (en) | 2001-07-23 | 2009-09-29 | Alcon, Inc. | Ophthalmic drug delivery device |
US7331984B2 (en) | 2001-08-28 | 2008-02-19 | Glaukos Corporation | Glaucoma stent for treating glaucoma and methods of use |
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2000
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- 2000-09-12 US US09/660,000 patent/US6413540B1/en not_active Expired - Lifetime
- 2000-09-12 PL PL355263A patent/PL196988B1/pl not_active IP Right Cessation
- 2000-09-12 EP EP00961836A patent/EP1221917B1/en not_active Expired - Lifetime
- 2000-09-12 KR KR1020027005020A patent/KR100732262B1/ko not_active IP Right Cessation
- 2000-09-12 DE DE60040876T patent/DE60040876D1/de not_active Expired - Lifetime
- 2000-09-12 AU AU73733/00A patent/AU768400B2/en not_active Ceased
- 2000-09-12 WO PCT/US2000/024983 patent/WO2001028472A1/en active IP Right Grant
- 2000-09-12 TR TR2002/01047T patent/TR200201047T2/xx unknown
- 2000-09-12 PT PT00961836T patent/PT1221917E/pt unknown
- 2000-09-12 ES ES04018677T patent/ES2315598T3/es not_active Expired - Lifetime
- 2000-09-12 JP JP2001531069A patent/JP4837861B2/ja not_active Expired - Fee Related
- 2000-09-12 CA CA002383499A patent/CA2383499C/en not_active Expired - Fee Related
- 2000-09-12 PT PT04018677T patent/PT1473003E/pt unknown
- 2000-09-12 MX MXPA02002338A patent/MXPA02002338A/es active IP Right Grant
- 2000-09-12 AT AT00961836T patent/ATE283013T1/de active
- 2000-09-12 ES ES00961836T patent/ES2231257T3/es not_active Expired - Lifetime
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2002
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- 2002-02-12 ZA ZA200201188A patent/ZA200201188B/en unknown
- 2002-07-01 US US10/186,960 patent/US6808719B2/en not_active Expired - Lifetime
- 2002-11-15 HK HK02108313.1A patent/HK1048427B/zh not_active IP Right Cessation
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2003
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2004
- 2004-03-02 AU AU2004200908A patent/AU2004200908B2/en not_active Ceased
- 2004-10-04 US US10/957,910 patent/US20050112175A1/en not_active Abandoned
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