YU64702A - Antiinfektivne kombinacije aktivnih supstanci i njihova primena za lokalno lečenje gljivičnih oboljenja noktiju na prstima nogu i ruku - Google Patents
Antiinfektivne kombinacije aktivnih supstanci i njihova primena za lokalno lečenje gljivičnih oboljenja noktiju na prstima nogu i rukuInfo
- Publication number
- YU64702A YU64702A YU64702A YUP64702A YU64702A YU 64702 A YU64702 A YU 64702A YU 64702 A YU64702 A YU 64702A YU P64702 A YUP64702 A YU P64702A YU 64702 A YU64702 A YU 64702A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- active substance
- toe
- antimycotic agent
- topical treatment
- substance combinations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Pronalazak se odnosi na preparat, koji sadrži kombinaciju aktivnih supstanci koja uključuje jedan antimikotik sa lokalnim dejstvom i jedan sistemski antimikotik i fiziološki prihvatljivu onsnovu laka. Preparat je podesan za lečenje onihomikoze. Prioritetno se koriste preparati na bazi laka, koji nije u vodi rastvoran, i kombinacije najmanje jednog sistemskog antimikotika iz grupe itraconazol, terbinafin i fluconazol ili njihovih soli i najmanje jedan antimikotik sa lokalnim dejstvom iz grupe ciclopirox, 6-(2,4,4-trimetilpentil)-1-hidroksi-4-metil-2(1H)-piridon, amorolfin i butenafin ili njihovih soli.[The invention relates to a preparation containing an active substance combination comprised of a topical antimycotic agent, of a systemic antimycotic agent, and of a physiologically safe lacquer base. The inventive preparation is suited for treating onychomycoses. The invention preferably uses water-insoluble lacquer preparations and a combination of at least one systemic antimycotic agent from the group containing itraconazole, terbinafine, fluconazole or the salts thereof with at least one topical antimycotic agent from the group containing ciclopirox 6-(2,4,4-trimethylpentyl)-1-hydroxy-4-methyl-2 (1H)-pyridone, amorolfine and butenafine or the salts thereof.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10011081A DE10011081A1 (de) | 2000-03-09 | 2000-03-09 | Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel |
Publications (2)
Publication Number | Publication Date |
---|---|
YU64702A true YU64702A (sh) | 2005-09-19 |
RS50450B RS50450B (sr) | 2010-03-02 |
Family
ID=7633836
Country Status (29)
Country | Link |
---|---|
US (2) | US20010046478A1 (sh) |
EP (1) | EP1267932B1 (sh) |
JP (1) | JP4843176B2 (sh) |
KR (1) | KR100766738B1 (sh) |
CN (1) | CN1216642C (sh) |
AT (1) | ATE259660T1 (sh) |
AU (2) | AU4648401A (sh) |
BR (1) | BRPI0108981B8 (sh) |
CA (1) | CA2402267C (sh) |
CZ (1) | CZ298718B6 (sh) |
DE (2) | DE10011081A1 (sh) |
DK (1) | DK1267932T3 (sh) |
EE (1) | EE04994B1 (sh) |
ES (1) | ES2211792T3 (sh) |
HK (1) | HK1054197B (sh) |
HR (1) | HRP20020731B1 (sh) |
HU (1) | HU228788B1 (sh) |
IL (2) | IL151519A0 (sh) |
ME (2) | MEP28808A (sh) |
MX (1) | MXPA02008292A (sh) |
NO (1) | NO330245B1 (sh) |
NZ (1) | NZ521226A (sh) |
PL (1) | PL200700B1 (sh) |
PT (1) | PT1267932E (sh) |
RS (1) | RS50450B (sh) |
RU (1) | RU2261701C2 (sh) |
SK (1) | SK287076B6 (sh) |
WO (1) | WO2001066145A1 (sh) |
ZA (1) | ZA200207213B (sh) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19639816A1 (de) * | 1996-09-27 | 1998-04-02 | Hoechst Ag | Antimykotische Mittel mit hoher Wirkstofffreisetzung |
US20040039030A1 (en) * | 1996-09-27 | 2004-02-26 | Hoechst Akeengesellschaft | Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis |
US6585963B1 (en) * | 2001-02-15 | 2003-07-01 | Watson Pharmaceuticals, Inc. | Nail compositions and methods of administering same |
US7244703B2 (en) * | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
GB0203276D0 (en) * | 2002-02-12 | 2002-03-27 | Novartis Ag | Organic compounds |
JP4081312B2 (ja) * | 2002-06-28 | 2008-04-23 | 佐藤製薬株式会社 | 外用抗真菌剤 |
DK1545619T3 (da) * | 2002-09-05 | 2008-05-26 | Galderma Sa | Oplösning til ungual påföring |
US7112561B2 (en) | 2003-12-08 | 2006-09-26 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for insulin treatment |
US8309103B2 (en) * | 2004-01-22 | 2012-11-13 | Alparis, S.A. De C.V. | Association of fluconazole-tinidazole for the treatment of vaginal infections, its composition, preparation process and usage |
US7740875B2 (en) * | 2004-10-08 | 2010-06-22 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US20060078580A1 (en) | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US20090036531A1 (en) * | 2005-02-22 | 2009-02-05 | Nguyen Tim T | Method for treatment of onychomycosis |
US20060251593A1 (en) * | 2005-04-07 | 2006-11-09 | Work By Docs, Inc. | Colored nail enamel treatment |
JP5010125B2 (ja) * | 2005-09-02 | 2012-08-29 | 有限会社日本健康科学研究センター | 水虫治療用フィルム製剤 |
US20070071705A1 (en) * | 2005-09-29 | 2007-03-29 | De Oliveira Monica A M | Topical anti-microbial compositions |
FR2892023B1 (fr) * | 2005-10-14 | 2009-09-25 | Galderma Sa | Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale |
MXPA05012961A (es) * | 2005-11-30 | 2007-05-30 | Fernando Ahumada Ayala | Preparaciones para el cuidado de las unas que contienen clorhidrato de terbinafina. |
RU2008131498A (ru) * | 2006-01-02 | 2010-02-10 | Тлт Медикал Лтд. (Ch) | Фармацевтическая композиция для лечения заболевний ногтей |
WO2007098591A2 (en) * | 2006-03-02 | 2007-09-07 | Nuvo Research Inc. | Topical nail formulation |
DE102008041049A1 (de) | 2008-08-06 | 2010-02-11 | Sonja Spohler | Verwendung einer antimykotischen Zusammensetzung zur topischen Behandlung von Pilzerkrankungen von Fuß- und Fingernägeln |
CN102319326A (zh) * | 2011-07-23 | 2012-01-18 | 李玮 | 一种治疗脚癣的浸药卫生纸 |
WO2013106566A1 (en) * | 2012-01-10 | 2013-07-18 | Arch Wood Protection, Inc. | Preservatives for wood |
CA2775393C (en) * | 2012-05-02 | 2014-04-29 | Samy Saad | Topical non-aqueous pharmaceutical formulations |
US8697753B1 (en) | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
KR101580077B1 (ko) | 2015-03-28 | 2015-12-24 | 한국콜마주식회사 | 시크로피록스 함유 네일락카 조성물 |
WO2017029387A1 (en) * | 2015-08-20 | 2017-02-23 | Galderma Sa | Method of improving visual appearance of nails affected by onychomycosis |
WO2017216722A2 (en) * | 2016-06-13 | 2017-12-21 | Vyome Biosciences Pvt. Ltd. | Synergistic antifungal compositions and methods thereof |
EP3468544A2 (en) * | 2016-06-13 | 2019-04-17 | Vyome Therapeutics Limited | Synergistic antifungal compositions and methods thereof |
CN106726750A (zh) * | 2016-12-09 | 2017-05-31 | 李晓光 | 一种环保抑菌护甲油及其制备方法 |
US20220211717A1 (en) * | 2021-01-04 | 2022-07-07 | Garry Alan Katz | Topical treatment of fungal infections of the hair, skin, and nails |
Family Cites Families (29)
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US202098A (en) * | 1878-04-09 | Improvement in harrow and weed-cutter | ||
US2134293A (en) * | 1936-06-04 | 1938-10-25 | Eastwood Nealley Corp | Woven wire fabric for dandy rolls, cylinder molds, or the like, for paper making machines |
US3968118A (en) * | 1968-08-31 | 1976-07-06 | Hoechst Aktiengesellschaft | Process for the manufacture of 1-hydroxy-2-pyridones |
US4185106A (en) * | 1972-07-11 | 1980-01-22 | Hoechst Aktiengesellschaft | Pyridones as antidandruff agents |
US4762703A (en) * | 1982-01-25 | 1988-08-09 | Dow Corning Corp. | Nitrocellulose free nail lacquer composition |
GB8302683D0 (en) * | 1983-02-01 | 1983-03-02 | Unilever Plc | Skin treatment composition |
AU599064B2 (en) * | 1985-11-04 | 1990-07-12 | Dermatological Products Of Texas | Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same |
DE3544983A1 (de) * | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
EP0241918B1 (de) * | 1986-04-18 | 1992-05-27 | Hoechst Aktiengesellschaft | 1-Hydroxy-2-pyridone, Verfahren zu ihrer Herstellung und Arzneimittel, die sie enthalten, sowie bei der Herstellung der 1-Hydroxy-2-pyridone gebildete Zwischenprodukte |
NL8601762A (nl) * | 1986-07-07 | 1988-02-01 | Bouke Jan Lange | Werkwijze voor de reiniging en conditionering en eventuele medicinale behandeling van het haar en de hoofdhuid, een voor dit doel bruikbare tweefasen shampoo, alsmede een verpakking daarvoor. |
DE3720147A1 (de) * | 1987-06-16 | 1988-12-29 | Hoechst Ag | Antimykotisch wirksamer nagellack sowie verfahren zu dessen herstellung |
CA2008775C (en) * | 1989-02-24 | 1998-12-22 | Alberto Ferro | Nail lacquer |
US5123107A (en) * | 1989-06-20 | 1992-06-16 | Mensch Jr William D | Topography of CMOS microcomputer integrated circuit chip including core processor and memory, priority, and I/O interface circuitry coupled thereto |
JPH0623087B2 (ja) * | 1989-10-09 | 1994-03-30 | 花王株式会社 | 洗浄剤組成物 |
US5066484A (en) * | 1990-04-30 | 1991-11-19 | Revlon, Inc. | Nail enamels containing glyceryl, glycol or citrate esters |
FR2673537B1 (fr) * | 1991-03-08 | 1993-06-11 | Oreal | Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes. |
HU223343B1 (hu) * | 1991-05-20 | 2004-06-28 | Novartis Ag. | Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására |
HU219480B (hu) * | 1991-05-23 | 2001-04-28 | Novartis Ag. | Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására |
DE4212105A1 (de) * | 1992-04-10 | 1993-10-14 | Roehm Pharma Gmbh | Nagellack zur Behandlung von Onychomykosen |
FR2697749B1 (fr) * | 1992-11-12 | 1995-01-13 | Oreal | Composition cosmétique filmogène à base d'un copolymère chloré greffé résultant du greffage d'une polyoléfine chlorée et de monomères insaturés du type acrylique, styrénique et/ou vinylique. |
DE4333893A1 (de) * | 1993-10-05 | 1995-04-06 | Hoechst Ag | Kosmetische Zubereitungen |
DE19518262A1 (de) * | 1995-05-18 | 1996-11-21 | Hoechst Ag | Die Verwendung von Glyceryltriacetat zur Behandlung von Onychomykosen |
US5424435A (en) * | 1993-10-18 | 1995-06-13 | Olin Corporation | 1-hydroxy-6-substituted-2-pyridones |
FR2718349B1 (fr) * | 1994-04-07 | 1996-05-31 | Oreal | Compositions cosmétiques à appliquer sur l'ongle. |
FR2719481B1 (fr) * | 1994-05-05 | 1996-05-31 | Oreal | Composition à base de composés antifongiques et de composés antibactériens halogènes pour diminuer la chute des cheveux. |
DE19604190A1 (de) * | 1996-02-06 | 1997-08-07 | Hoechst Ag | Nagelwachstumsfördernde Zubereitungen |
US6169721B1 (en) * | 1997-08-27 | 2001-01-02 | Pioneer Electronic Corporation | Two-disc laminated optical recording medium |
PT983037E (pt) * | 1998-02-09 | 2003-09-30 | Macrochem Corp | Verniz para unhas antifungico |
US6231875B1 (en) * | 1998-03-31 | 2001-05-15 | Johnson & Johnson Consumer Companies, Inc. | Acidified composition for topical treatment of nail and skin conditions |
-
2000
- 2000-03-09 DE DE10011081A patent/DE10011081A1/de not_active Withdrawn
-
2001
- 2001-02-28 JP JP2001564797A patent/JP4843176B2/ja not_active Expired - Lifetime
- 2001-02-28 RU RU2002126618/15A patent/RU2261701C2/ru active
- 2001-02-28 ES ES01919354T patent/ES2211792T3/es not_active Expired - Lifetime
- 2001-02-28 AU AU4648401A patent/AU4648401A/xx active Pending
- 2001-02-28 MX MXPA02008292A patent/MXPA02008292A/es active IP Right Grant
- 2001-02-28 SK SK1276-2002A patent/SK287076B6/sk not_active IP Right Cessation
- 2001-02-28 IL IL15151901A patent/IL151519A0/xx unknown
- 2001-02-28 CA CA002402267A patent/CA2402267C/en not_active Expired - Lifetime
- 2001-02-28 DK DK01919354T patent/DK1267932T3/da active
- 2001-02-28 CZ CZ20023001A patent/CZ298718B6/cs not_active IP Right Cessation
- 2001-02-28 PT PT01919354T patent/PT1267932E/pt unknown
- 2001-02-28 AT AT01919354T patent/ATE259660T1/de active
- 2001-02-28 PL PL359705A patent/PL200700B1/pl unknown
- 2001-02-28 RS YUP-647/02A patent/RS50450B/sr unknown
- 2001-02-28 CN CN018062075A patent/CN1216642C/zh not_active Expired - Lifetime
- 2001-02-28 AU AU2001246484A patent/AU2001246484B2/en not_active Expired
- 2001-02-28 ME MEP-288/08A patent/MEP28808A/xx unknown
- 2001-02-28 HU HU0300135A patent/HU228788B1/hu unknown
- 2001-02-28 ME MEP-2008-288A patent/ME00177B/me unknown
- 2001-02-28 WO PCT/EP2001/002236 patent/WO2001066145A1/de active IP Right Grant
- 2001-02-28 EP EP01919354A patent/EP1267932B1/de not_active Expired - Lifetime
- 2001-02-28 KR KR1020027011812A patent/KR100766738B1/ko active IP Right Grant
- 2001-02-28 NZ NZ521226A patent/NZ521226A/en not_active IP Right Cessation
- 2001-02-28 DE DE50101510T patent/DE50101510D1/de not_active Expired - Lifetime
- 2001-02-28 BR BRPI0108981A patent/BRPI0108981B8/pt not_active IP Right Cessation
- 2001-02-28 EE EEP200200482A patent/EE04994B1/xx unknown
- 2001-03-07 US US09/799,726 patent/US20010046478A1/en not_active Abandoned
-
2002
- 2002-08-28 IL IL151519A patent/IL151519A/en active IP Right Grant
- 2002-09-05 HR HR20020731A patent/HRP20020731B1/xx not_active IP Right Cessation
- 2002-09-06 NO NO20024271A patent/NO330245B1/no not_active IP Right Cessation
- 2002-09-06 ZA ZA200207213A patent/ZA200207213B/en unknown
- 2002-12-16 US US10/319,626 patent/US20030086881A1/en not_active Abandoned
-
2003
- 2003-09-11 HK HK03106498.1A patent/HK1054197B/zh not_active IP Right Cessation
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