YU64702A - Antiinfektivne kombinacije aktivnih supstanci i njihova primena za lokalno lečenje gljivičnih oboljenja noktiju na prstima nogu i ruku - Google Patents

Antiinfektivne kombinacije aktivnih supstanci i njihova primena za lokalno lečenje gljivičnih oboljenja noktiju na prstima nogu i ruku

Info

Publication number
YU64702A
YU64702A YU64702A YUP64702A YU64702A YU 64702 A YU64702 A YU 64702A YU 64702 A YU64702 A YU 64702A YU P64702 A YUP64702 A YU P64702A YU 64702 A YU64702 A YU 64702A
Authority
YU
Yugoslavia
Prior art keywords
active substance
toe
antimycotic agent
topical treatment
substance combinations
Prior art date
Application number
YU64702A
Other languages
English (en)
Inventor
Manfred Bohn
Karl Theodor Kraemer
Original Assignee
Aventis Pharma Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh. filed Critical Aventis Pharma Deutschland Gmbh.
Publication of YU64702A publication Critical patent/YU64702A/sh
Publication of RS50450B publication Critical patent/RS50450B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Pronalazak se odnosi na preparat, koji sadrži kombinaciju aktivnih supstanci koja uključuje jedan antimikotik sa lokalnim dejstvom i jedan sistemski antimikotik i fiziološki prihvatljivu onsnovu laka. Preparat je podesan za lečenje onihomikoze. Prioritetno se koriste preparati na bazi laka, koji nije u vodi rastvoran, i kombinacije najmanje jednog sistemskog antimikotika iz grupe itraconazol, terbinafin i fluconazol ili njihovih soli i najmanje jedan antimikotik sa lokalnim dejstvom iz grupe ciclopirox, 6-(2,4,4-trimetilpentil)-1-hidroksi-4-metil-2(1H)-piridon, amorolfin i butenafin ili njihovih soli.[The invention relates to a preparation containing an active substance combination comprised of a topical antimycotic agent, of a systemic antimycotic agent, and of a physiologically safe lacquer base. The inventive preparation is suited for treating onychomycoses. The invention preferably uses water-insoluble lacquer preparations and a combination of at least one systemic antimycotic agent from the group containing itraconazole, terbinafine, fluconazole or the salts thereof with at least one topical antimycotic agent from the group containing ciclopirox 6-(2,4,4-trimethylpentyl)-1-hydroxy-4-methyl-2 (1H)-pyridone, amorolfine and butenafine or the salts thereof.
YUP-647/02A 2000-03-09 2001-02-28 Antiinfektivne kombinacije aktivnih supstanci i njihova primena za topikalno lečenje gljivičnih oboljenja noktiju na prstima nogu i ruku RS50450B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10011081A DE10011081A1 (de) 2000-03-09 2000-03-09 Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel

Publications (2)

Publication Number Publication Date
YU64702A true YU64702A (sh) 2005-09-19
RS50450B RS50450B (sr) 2010-03-02

Family

ID=7633836

Country Status (29)

Country Link
US (2) US20010046478A1 (sh)
EP (1) EP1267932B1 (sh)
JP (1) JP4843176B2 (sh)
KR (1) KR100766738B1 (sh)
CN (1) CN1216642C (sh)
AT (1) ATE259660T1 (sh)
AU (2) AU4648401A (sh)
BR (1) BRPI0108981B8 (sh)
CA (1) CA2402267C (sh)
CZ (1) CZ298718B6 (sh)
DE (2) DE10011081A1 (sh)
DK (1) DK1267932T3 (sh)
EE (1) EE04994B1 (sh)
ES (1) ES2211792T3 (sh)
HK (1) HK1054197B (sh)
HR (1) HRP20020731B1 (sh)
HU (1) HU228788B1 (sh)
IL (2) IL151519A0 (sh)
ME (2) MEP28808A (sh)
MX (1) MXPA02008292A (sh)
NO (1) NO330245B1 (sh)
NZ (1) NZ521226A (sh)
PL (1) PL200700B1 (sh)
PT (1) PT1267932E (sh)
RS (1) RS50450B (sh)
RU (1) RU2261701C2 (sh)
SK (1) SK287076B6 (sh)
WO (1) WO2001066145A1 (sh)
ZA (1) ZA200207213B (sh)

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KR101580077B1 (ko) 2015-03-28 2015-12-24 한국콜마주식회사 시크로피록스 함유 네일락카 조성물
WO2017029387A1 (en) * 2015-08-20 2017-02-23 Galderma Sa Method of improving visual appearance of nails affected by onychomycosis
EP3468544A2 (en) * 2016-06-13 2019-04-17 Vyome Therapeutics Limited Synergistic antifungal compositions and methods thereof
WO2017216722A2 (en) * 2016-06-13 2017-12-21 Vyome Biosciences Pvt. Ltd. Synergistic antifungal compositions and methods thereof
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Also Published As

Publication number Publication date
BRPI0108981B8 (pt) 2021-05-25
EP1267932B1 (de) 2004-02-18
PT1267932E (pt) 2004-07-30
HUP0300135A3 (en) 2005-04-28
DE10011081A1 (de) 2001-09-13
ATE259660T1 (de) 2004-03-15
MXPA02008292A (es) 2002-12-09
CN1416353A (zh) 2003-05-07
RU2261701C2 (ru) 2005-10-10
BR0108981A (pt) 2003-06-03
KR20030016237A (ko) 2003-02-26
BR0108981B1 (pt) 2014-01-07
ZA200207213B (en) 2003-02-26
ME00177B (me) 2011-02-10
CN1216642C (zh) 2005-08-31
ES2211792T3 (es) 2004-07-16
SK287076B6 (sk) 2009-11-05
CZ298718B6 (cs) 2008-01-09
NO20024271D0 (no) 2002-09-06
NO20024271L (no) 2002-10-18
IL151519A0 (en) 2003-04-10
IL151519A (en) 2011-07-31
HUP0300135A2 (hu) 2003-06-28
DK1267932T3 (da) 2004-06-01
EP1267932A1 (de) 2003-01-02
WO2001066145A1 (de) 2001-09-13
SK12762002A3 (sk) 2003-04-01
US20030086881A1 (en) 2003-05-08
AU4648401A (en) 2001-09-17
NZ521226A (en) 2004-08-27
CZ20023001A3 (cs) 2002-11-13
CA2402267A1 (en) 2001-09-13
HRP20020731B1 (en) 2011-07-31
MEP28808A (en) 2010-10-10
EE04994B1 (et) 2008-04-15
HK1054197A1 (en) 2003-11-21
JP2003525910A (ja) 2003-09-02
CA2402267C (en) 2009-10-20
AU2001246484B2 (en) 2005-04-14
RS50450B (sr) 2010-03-02
PL200700B1 (pl) 2009-01-30
US20010046478A1 (en) 2001-11-29
NO330245B1 (no) 2011-03-14
JP4843176B2 (ja) 2011-12-21
PL359705A1 (en) 2004-09-06
EE200200482A (et) 2004-02-16
HK1054197B (zh) 2005-12-16
KR100766738B1 (ko) 2007-10-15
HU228788B1 (en) 2013-05-28
DE50101510D1 (de) 2004-03-25
HRP20020731A2 (en) 2004-12-31

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