YU58103A - Farmaceutski preparati, dozirane forme i postupci za oralnu primenu epotilona - Google Patents

Farmaceutski preparati, dozirane forme i postupci za oralnu primenu epotilona

Info

Publication number
YU58103A
YU58103A YU58103A YUP58103A YU58103A YU 58103 A YU58103 A YU 58103A YU 58103 A YU58103 A YU 58103A YU P58103 A YUP58103 A YU P58103A YU 58103 A YU58103 A YU 58103A
Authority
YU
Yugoslavia
Prior art keywords
epothilones
dosage forms
pharmaceutical dosage
oral administration
methods
Prior art date
Application number
YU58103A
Other languages
English (en)
Inventor
Rebanta Bandyopadhyay
Timothy M. Malloy
Andrea Panaggio
Krishnaswamy Srinivas Raghavan
Sailesh Amilal Varia
Original Assignee
Bristol-Myers Squibb Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Co. filed Critical Bristol-Myers Squibb Co.
Publication of YU58103A publication Critical patent/YU58103A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Pronalasci su povezani sa postupcima povećanja bioraspoloživosti oralno primenjenih epotilona. Primenjeni epotiloni su smanjene bioraspoloživosti da daju farmakološki efekat. Buduća istraživanja povezana su sa farmaceutskim jedinjenjima, farmaceutskim doziranim oblicima i kitovima za korišćenje u ovim pronalascima.[The invention relates to methods of increasing the bioavailability of orally administered epothilones. Epothilones administered by the methods of the invention are sufficiently bioavailable to have a pharmacological effect. The invention further relates to pharmaceutical compositions, pharmaceutical dosage forms, and kits for use in the methods of the invention.
YU58103A 2001-01-25 2002-01-25 Farmaceutski preparati, dozirane forme i postupci za oralnu primenu epotilona YU58103A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26422801P 2001-01-25 2001-01-25
US29001901P 2001-05-11 2001-05-11

Publications (1)

Publication Number Publication Date
YU58103A true YU58103A (sh) 2006-03-03

Family

ID=26950349

Family Applications (1)

Application Number Title Priority Date Filing Date
YU58103A YU58103A (sh) 2001-01-25 2002-01-25 Farmaceutski preparati, dozirane forme i postupci za oralnu primenu epotilona

Country Status (26)

Country Link
US (2) US6576651B2 (sh)
EP (1) EP1361877A1 (sh)
JP (1) JP2004528287A (sh)
KR (1) KR20040025888A (sh)
CN (1) CN1268336C (sh)
AR (1) AR035078A1 (sh)
BG (1) BG108027A (sh)
BR (1) BR0206695A (sh)
CA (1) CA2434584A1 (sh)
CZ (1) CZ20032023A3 (sh)
EE (1) EE200300329A (sh)
HR (1) HRP20030674A2 (sh)
HU (1) HUP0303800A3 (sh)
IL (1) IL156759A0 (sh)
IS (1) IS6892A (sh)
MX (1) MXPA03006476A (sh)
NO (1) NO20033343L (sh)
NZ (1) NZ526871A (sh)
PE (1) PE20020853A1 (sh)
PL (1) PL368636A1 (sh)
RU (1) RU2291695C2 (sh)
SK (1) SK9212003A3 (sh)
TW (1) TWI250017B (sh)
UY (1) UY27138A1 (sh)
WO (2) WO2002058699A1 (sh)
YU (1) YU58103A (sh)

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US6867305B2 (en) 1996-12-03 2005-03-15 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
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US8618085B2 (en) * 2000-04-28 2013-12-31 Koasn Biosciences Incorporated Therapeutic formulations of desoxyepothilones
NZ526871A (en) 2001-01-25 2006-01-27 Bristol Myers Squibb Co Pharmaceutical dosage forms of epothilones for oral administration
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WO2002066038A1 (en) 2001-02-20 2002-08-29 Bristol-Myers Squibb Company Treatment of refractory tumors using epothilone derivatives
ES2384789T3 (es) * 2001-03-14 2012-07-12 Bristol-Myers Squibb Company Combinación de un análogo de epotilona y agentes quimioterapéuticos para el tratamiento de enfermedades proliferativas
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AU2003218107A1 (en) * 2002-03-12 2003-09-29 Bristol-Myers Squibb Company C12-cyano epothilone derivatives
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US7649006B2 (en) * 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
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US8053159B2 (en) 2003-11-18 2011-11-08 Honeywell International Inc. Antireflective coatings for via fill and photolithography applications and methods of preparation thereof
US20090004277A1 (en) * 2004-05-18 2009-01-01 Franchini Miriam K Nanoparticle dispersion containing lactam compound
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AR057325A1 (es) * 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
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CN102276433B (zh) * 2011-06-30 2016-04-20 南昌大学 木豆素c及其衍生物及其在制备抗癌药物中的应用
JP6803842B2 (ja) 2015-04-13 2020-12-23 ハネウェル・インターナショナル・インコーポレーテッドＨｏｎｅｙｗｅｌｌ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃ． オプトエレクトロニクス用途のためのポリシロキサン製剤及びコーティング

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Also Published As

Publication number Publication date
KR20040025888A (ko) 2004-03-26
JP2004528287A (ja) 2004-09-16
NO20033343L (no) 2003-09-24
HUP0303800A2 (hu) 2004-03-29
UY27138A1 (es) 2002-08-30
AU2002253880B2 (en) 2006-11-09
CA2434584A1 (en) 2002-08-01
SK9212003A3 (en) 2004-11-03
PE20020853A1 (es) 2002-09-27
TWI250017B (en) 2006-03-01
NO20033343D0 (no) 2003-07-24
NZ526871A (en) 2006-01-27
CN1268336C (zh) 2006-08-09
CN1498106A (zh) 2004-05-19
IS6892A (is) 2003-07-24
EE200300329A (et) 2003-10-15
MXPA03006476A (es) 2003-09-22
HRP20030674A2 (en) 2005-06-30
US6576651B2 (en) 2003-06-10
HUP0303800A3 (en) 2005-02-28
IL156759A0 (en) 2004-02-08
RU2003126174A (ru) 2005-02-27
EP1361877A1 (en) 2003-11-19
PL368636A1 (en) 2005-04-04
RU2291695C2 (ru) 2007-01-20
BG108027A (bg) 2004-12-30
CZ20032023A3 (cs) 2005-03-16
AR035078A1 (es) 2004-04-14
BR0206695A (pt) 2004-04-20
US20020177615A1 (en) 2002-11-28
WO2002058701A1 (en) 2002-08-01
USRE40387E1 (en) 2008-06-17
WO2002058699A1 (en) 2002-08-01

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