YU49494B - Primena 1-hidroksi-2-piridona za dobijanje leka za lečenje infekcije kože - Google Patents

Primena 1-hidroksi-2-piridona za dobijanje leka za lečenje infekcije kože

Info

Publication number
YU49494B
YU49494B YU13699A YU13699A YU49494B YU 49494 B YU49494 B YU 49494B YU 13699 A YU13699 A YU 13699A YU 13699 A YU13699 A YU 13699A YU 49494 B YU49494 B YU 49494B
Authority
YU
Yugoslavia
Prior art keywords
atoms
alkyl
residues
residue
bromine
Prior art date
Application number
YU13699A
Other languages
English (en)
Other versions
YU13699A (sh
Inventor
Manfred Bohn
Karl Theodor Kraemer
Astrid Markus
Original Assignee
Sanofi-Aventis Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis Deutschland Gmbh. filed Critical Sanofi-Aventis Deutschland Gmbh.
Publication of YU13699A publication Critical patent/YU13699A/sh
Publication of YU49494B publication Critical patent/YU49494B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Primena 1-hidroksi-2-prirodna za dobijanej leka za lečenje infekcije kože prema formuli I: pri čemu R1, R2 i R3, koji su isti ili različiti, predstavljaju atom vodonika ili alkil sa 1 do 4 atoma ugljenika, a R4 predstavlja zasićen ostatak ugljovodonika sa 6 do 9 atoma ugljenika ili ostatak prema formuli II: X označava S ili O, Y označava atom vodonika ili do 2 atoma halogena kao što su hlor i/ili brom; Z označava jednogubu vezu ili dvovalentni ostatak O, S, -CR2-(R=H ili (C1-C4)-alkil) ili druge dvovalentne ostatke sa 2 do 10 C-atoma u lancu i eventualno O-atoma i/ili S-atoma, pri čemu ako ostaci imaju 2 ili više O-atoma i/iliS-atoma ovi poslednje navedeni moraju biti međusobno razdvojeni sa najmanje 2 C-atoma, pri čemu dva susedna C-atoma mogu biti međusobno vezani dvostrukom vezom, dok su slobodne veze C-atoma zasićene H i/ili (C1-C4)-alkil grupama; Ar označava aromatični prstenasti sistem sa dva prstena, koji mogu biti supstituisani sa do tri ostatka iz grupe flour, hlor, brom, metoksi, (C1-C4)-alkil, trifluormetil i trifluormetoksi, gde se jedinjenja primenjuju za dobijanje leka za lečenje infekcije kože uzrokovanih bakterijama rezistentnim na antibiotike. Prijava sadrži još 5 zavisnih patentnih zahteva.
YU13699A 1996-09-27 1997-09-16 Primena 1-hidroksi-2-piridona za dobijanje leka za lečenje infekcije kože YU49494B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19639817A DE19639817A1 (de) 1996-09-27 1996-09-27 Verwendung von 1-Hydroxy-2-pyridonen zur Behandlung von Hautinfektionen

Publications (2)

Publication Number Publication Date
YU13699A YU13699A (sh) 1999-12-27
YU49494B true YU49494B (sh) 2006-08-17

Family

ID=7807117

Family Applications (1)

Application Number Title Priority Date Filing Date
YU13699A YU49494B (sh) 1996-09-27 1997-09-16 Primena 1-hidroksi-2-piridona za dobijanje leka za lečenje infekcije kože

Country Status (33)

Country Link
US (1) US6469033B1 (sh)
EP (1) EP0928193B1 (sh)
JP (1) JP4203125B2 (sh)
KR (1) KR100457851B1 (sh)
CN (1) CN1141096C (sh)
AR (1) AR008859A1 (sh)
AT (1) ATE218862T1 (sh)
AU (1) AU717333B2 (sh)
BG (1) BG64370B1 (sh)
BR (1) BR9712141A (sh)
CA (1) CA2267309C (sh)
CZ (1) CZ290701B6 (sh)
DE (2) DE19639817A1 (sh)
DK (1) DK0928193T3 (sh)
ES (1) ES2178761T3 (sh)
HK (1) HK1022269A1 (sh)
HU (1) HU226911B1 (sh)
ID (1) ID21948A (sh)
IL (1) IL129144A0 (sh)
MA (1) MA24332A1 (sh)
MY (1) MY117381A (sh)
NO (1) NO322072B1 (sh)
NZ (1) NZ334848A (sh)
OA (1) OA11027A (sh)
PL (1) PL190298B1 (sh)
PT (1) PT928193E (sh)
RU (1) RU2203059C2 (sh)
TR (1) TR199900661T2 (sh)
TW (1) TW531418B (sh)
UA (1) UA56192C2 (sh)
WO (1) WO1998013043A1 (sh)
YU (1) YU49494B (sh)
ZA (1) ZA978639B (sh)

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WO2005110988A1 (en) * 2004-05-07 2005-11-24 Janssen Pharmaceutica, N.V. Pyridone compounds as inhibitors of bacterial type iii protein secretion systems
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US20070071705A1 (en) * 2005-09-29 2007-03-29 De Oliveira Monica A M Topical anti-microbial compositions
EP2750505A4 (en) 2011-08-29 2015-08-05 Ptc Therapeutics Inc ANTIBACTERIAL COMPOUNDS AND METHODS FOR THEIR USE
KR20140097118A (ko) * 2011-08-29 2014-08-06 피티씨 테라퓨틱스, 인크. 항균 화합물 및 이의 사용 방법
CN103360308A (zh) * 2012-03-28 2013-10-23 孙伟新 1,4-二羟基-6-甲基-2-吡啶酮类化合物及其制备方法和用途
DE102015219008A1 (de) 2015-10-01 2017-04-06 Beiersdorf Ag Sonnenschutzmittel mit reduzierter Textilverfleckung durch 4-(tert.-Butyl)-4'-methoxydibenzoylmethan
DE102015219009A1 (de) 2015-10-01 2017-04-06 Beiersdorf Ag Sonnenschutzmittel mit reduzierter Textilverfleckung durch Diethylamino Hydroxybenzoyl Hexyl Benzoate
DE102015219006A1 (de) 2015-10-01 2017-04-20 Beiersdorf Ag Sonnenschutzmittel mit reduzierter Textilverfleckung durch Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine
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Also Published As

Publication number Publication date
IL129144A0 (en) 2000-02-17
CZ107499A3 (cs) 1999-07-14
CN1141096C (zh) 2004-03-10
HUP9904317A3 (en) 2001-07-30
CN1231610A (zh) 1999-10-13
NO991459D0 (no) 1999-03-25
RU2203059C2 (ru) 2003-04-27
TW531418B (en) 2003-05-11
YU13699A (sh) 1999-12-27
JP4203125B2 (ja) 2008-12-24
DE59707519D1 (de) 2002-07-18
ES2178761T3 (es) 2003-01-01
NZ334848A (en) 2000-09-29
AU4774597A (en) 1998-04-17
ZA978639B (en) 1998-03-27
AR008859A1 (es) 2000-02-23
KR100457851B1 (ko) 2004-11-18
PL190298B1 (pl) 2005-11-30
JP2001501200A (ja) 2001-01-30
KR20000048674A (ko) 2000-07-25
AU717333B2 (en) 2000-03-23
ATE218862T1 (de) 2002-06-15
HK1022269A1 (en) 2000-08-04
PL332579A1 (en) 1999-09-27
CA2267309A1 (en) 1998-04-02
DE19639817A1 (de) 1998-04-02
EP0928193B1 (de) 2002-06-12
EP0928193A1 (de) 1999-07-14
NO991459L (no) 1999-03-25
MA24332A1 (fr) 1998-04-01
HU226911B1 (en) 2010-03-01
ID21948A (id) 1999-08-12
HUP9904317A2 (hu) 2000-05-28
UA56192C2 (uk) 2003-05-15
US6469033B1 (en) 2002-10-22
BG64370B1 (bg) 2004-12-30
NO322072B1 (no) 2006-08-07
MY117381A (en) 2004-06-30
DK0928193T3 (da) 2002-10-07
OA11027A (fr) 2003-03-06
WO1998013043A1 (de) 1998-04-02
BG103261A (en) 1999-09-30
TR199900661T2 (xx) 1999-06-21
PT928193E (pt) 2002-11-29
BR9712141A (pt) 1999-08-31
CZ290701B6 (cs) 2002-09-11
CA2267309C (en) 2006-02-21

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