PT771197E - Utilizacao de compostos heterociclicos como ligantes de dopamina-d 3 - Google Patents

Utilizacao de compostos heterociclicos como ligantes de dopamina-d 3

Info

Publication number
PT771197E
PT771197E PT95926896T PT95926896T PT771197E PT 771197 E PT771197 E PT 771197E PT 95926896 T PT95926896 T PT 95926896T PT 95926896 T PT95926896 T PT 95926896T PT 771197 E PT771197 E PT 771197E
Authority
PT
Portugal
Prior art keywords
dopamine
pct
heterocyclic compounds
ligants
utilization
Prior art date
Application number
PT95926896T
Other languages
English (en)
Inventor
Beate Hellendahl
Liliane Unger
Hans-Juergen Teschendorf
Annegret Lansky
Alfred Bach
Beatrice Rendenbach-Mueller
Carsten Wicke
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of PT771197E publication Critical patent/PT771197E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PT95926896T 1994-07-15 1995-07-14 Utilizacao de compostos heterociclicos como ligantes de dopamina-d 3 PT771197E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4425146A DE4425146A1 (de) 1994-07-15 1994-07-15 Verwendung heterocyclischer Verbindungen

Publications (1)

Publication Number Publication Date
PT771197E true PT771197E (pt) 2003-08-29

Family

ID=6523325

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95926896T PT771197E (pt) 1994-07-15 1995-07-14 Utilizacao de compostos heterociclicos como ligantes de dopamina-d 3

Country Status (22)

Country Link
US (1) US6090807A (pt)
EP (1) EP0771197B1 (pt)
JP (1) JPH10502658A (pt)
KR (2) KR100443850B1 (pt)
CN (2) CN1152870A (pt)
AT (1) ATE236629T1 (pt)
AU (1) AU704839B2 (pt)
BG (1) BG63487B1 (pt)
BR (1) BR9508296A (pt)
CA (1) CA2195242A1 (pt)
CZ (1) CZ293126B6 (pt)
DE (2) DE4425146A1 (pt)
DK (1) DK0771197T3 (pt)
ES (1) ES2196072T3 (pt)
FI (1) FI970148A (pt)
HU (1) HUT77608A (pt)
MX (1) MX9700430A (pt)
NO (1) NO311683B1 (pt)
NZ (1) NZ290388A (pt)
PT (1) PT771197E (pt)
SI (1) SI9520084B (pt)
WO (1) WO1996002246A1 (pt)

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AU4204697A (en) * 1996-08-14 1998-03-06 Smithkline Beecham Plc Tetrahydroisoquinoline derivatives and their pharmaceutical use
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GB9708805D0 (en) * 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
GB9709303D0 (en) * 1997-05-09 1997-06-25 Smithkline Beecham Plc Compounds
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
TW530054B (en) * 1997-09-24 2003-05-01 Duphar Int Res New piperazine and piperidine compounds
US6632823B1 (en) 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
US6218396B1 (en) * 1998-02-20 2001-04-17 Orth-Mcneil Pharmaceutical, Inc. Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia
GB9810876D0 (en) 1998-05-20 1998-07-22 Smithkline Beecham Plc Compounds
ID28385A (id) 1998-10-08 2001-05-17 Smithkline Beecham Plc Turunan-turunan tetrahidrobenzazepina yang berguna sebagai modulator reseptor d3 dopamina (bahan antipsikotik)
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GB9923748D0 (en) * 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
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US6365591B1 (en) 1999-10-18 2002-04-02 Recordati, S.A., Chemical And Pharmacueticals Company Isoxazolecarboxamide derivatives
EP1272187B1 (de) * 2000-03-27 2008-07-30 Abbott GmbH & Co. KG Dopamin-d3-rezeptor-liganden zur behandlung von sucht
GB0025354D0 (en) * 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
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GB0108594D0 (en) * 2001-04-05 2001-05-23 Glaxo Group Ltd Chemical compounds
HUP0103987A3 (en) * 2001-09-28 2004-11-29 Richter Gedeon Vegyeszet Phenylpiperazinylalkyl carboxylic acid amid derivatives, process for their preparation, pharmaceutical compositions containing them and their intermediates
GB0203020D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
JP2005522436A (ja) * 2002-02-08 2005-07-28 グラクソ　グループ　リミテッド ピペリジルカルボキシアミド誘導体またはそのタキキニン介在疾患の治療における使用
GB0203022D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
DK1519726T3 (da) * 2002-07-04 2007-06-04 Sanol Arznei Schwarz Gmbh Heteroarencarboxamider til anvendelse som dopamin-D3-ligander til behandling af CNS-sygdomme
DE10232020A1 (de) * 2002-07-04 2004-02-26 Friedrich-Alexander-Universität Erlangen-Nürnberg Neurorezeptoraktive Heteroarencarboxamide
TW200507841A (en) * 2003-03-27 2005-03-01 Glaxo Group Ltd Antibacterial agents
DE10315569A1 (de) * 2003-04-05 2004-10-14 Merck Patent Gmbh Substituierte Pyrazolverbindungen
US7320979B2 (en) * 2003-04-14 2008-01-22 Abbott Gmbh & Co. Kg. N-[(piperazinyl)hetaryl]arylsulfonamide compounds
US20040204422A1 (en) 2003-04-14 2004-10-14 Abbott Gmbh & Co. Kg. N-[(Piperazinyl)hetaryl]arylsulfonamide compounds
DE10358004A1 (de) 2003-12-11 2005-07-14 Abbott Gmbh & Co. Kg Ketolactam-Verbindungen und ihre Verwendung
US20050137186A1 (en) 2003-12-18 2005-06-23 Abbott Gmbh & Co. Kg. Tetrahydrobenzazepines and their use
EP1694334B1 (en) 2003-12-18 2011-10-19 Abbott GmbH & Co. KG Tetrahydrobenzazepines and their use in the modulation of the dopamine d3 receptor
DE102004027358A1 (de) 2004-06-04 2005-12-29 Abbott Gmbh & Co. Kg Pyrimidinverbindungen und ihre Verwendung
DE102004027359A1 (de) 2004-06-04 2005-12-29 Abbott Gmbh & Co. Kg Pyridin-2-onverbindungen und deren Verwendung
MX2007001530A (es) 2004-08-09 2007-04-23 Abbott Gmbh & Co Kg Compuestos de 4-piperazinil-pirimidina adecuados para tratar trastornos que responde a la modulacion del receptor dopamina d3.
NZ555491A (en) * 2005-01-03 2010-01-29 Univ Siena Aryl piperazine derivatives for the treatment of neuropsychiatric disorders
JP2008528604A (ja) * 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
PA8802101A1 (es) 2007-11-02 2009-08-26 Abbott Gmbh & Co Kg Compuestos de 1,2,4-3,5-diona adecuados para el tratamiento de trastornos que responden a la modulación del receptor de dopamina d3
US20110059019A1 (en) * 2008-02-01 2011-03-10 Neurosearch A/S Novel aryl piperazine derivatives useful as modulators of dopamine and serotonin receptors
US9227944B2 (en) 2008-10-10 2016-01-05 Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China Dopamine D3 receptor ligands and preparation and medical uses of the same
US8829001B2 (en) 2008-10-10 2014-09-09 The Institute of Pharmacology and Toxicology Academy of Military Medical Science P.L.A. China Dopamine D3 receptor ligands and preparation and medical uses of the same
EP2451796B1 (en) 2009-07-08 2013-04-17 Dermira (Canada), Inc. Tofa analogs useful in treating dermatological disorders or conditions
US8609672B2 (en) 2010-08-27 2013-12-17 University Of The Pacific Piperazinylpyrimidine analogues as protein kinase inhibitors
US20130289047A1 (en) * 2010-10-14 2013-10-31 Epiomed Therapeutics, Inc. Heteroarylthio derivatives and analogues
US9199975B2 (en) 2011-09-30 2015-12-01 Asana Biosciences, Llc Biaryl imidazole derivatives for regulating CYP17
CN102408397B (zh) 2011-10-19 2014-08-20 上海贝美医药科技有限公司 紫杉烷类衍生物及其制备方法
WO2023144764A1 (en) 2022-01-29 2023-08-03 Suven Life Sciences Limited Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders

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Also Published As

Publication number Publication date
EP0771197B1 (de) 2003-04-09
KR20040000412A (ko) 2004-01-03
KR970704435A (ko) 1997-09-06
AU704839B2 (en) 1999-05-06
SI9520084A (en) 1997-08-31
BG63487B1 (bg) 2002-03-29
CA2195242A1 (en) 1996-02-01
FI970148A0 (fi) 1997-01-14
NO970163L (no) 1997-03-14
DE4425146A1 (de) 1996-01-18
DE59510635D1 (de) 2003-05-15
HU9700111D0 (en) 1997-02-28
MX9700430A (es) 1998-05-31
HUT77608A (hu) 1998-06-29
ES2196072T3 (es) 2003-12-16
AU3111495A (en) 1996-02-16
CN1152870A (zh) 1997-06-25
FI970148A (fi) 1997-01-14
BR9508296A (pt) 1998-05-19
US6090807A (en) 2000-07-18
NO311683B1 (no) 2002-01-07
NZ290388A (en) 2001-04-27
JPH10502658A (ja) 1998-03-10
CZ293126B6 (cs) 2004-02-18
EP0771197A1 (de) 1997-05-07
BG101112A (en) 1998-04-30
WO1996002246A1 (de) 1996-02-01
CZ9697A3 (en) 1997-08-13
DK0771197T3 (da) 2003-06-23
CN1534023A (zh) 2004-10-06
KR100443850B1 (ko) 2004-08-11
ATE236629T1 (de) 2003-04-15
NO970163D0 (no) 1997-01-14
SI9520084B (sl) 2005-02-28

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