YU46222B - Postupak za dobijanje novih (benzofuran-2-il)imidazola - Google Patents

Postupak za dobijanje novih (benzofuran-2-il)imidazola

Info

Publication number
YU46222B
YU46222B YU150787A YU150787A YU46222B YU 46222 B YU46222 B YU 46222B YU 150787 A YU150787 A YU 150787A YU 150787 A YU150787 A YU 150787A YU 46222 B YU46222 B YU 46222B
Authority
YU
Yugoslavia
Prior art keywords
atoms
group
halogen
alkyl moiety
alkyl
Prior art date
Application number
YU150787A
Other languages
English (en)
Other versions
YU150787A (en
Inventor
V. Pestellini
M. Ghelardoni
D. Giannotti
A. Giolitti
A. Barzanti
R. Ciappi
C. Ortolani
Original Assignee
A. Menarini S.A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A. Menarini S.A.S. filed Critical A. Menarini S.A.S.
Publication of YU150787A publication Critical patent/YU150787A/xx
Publication of YU46222B publication Critical patent/YU46222B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

koji mogu biti različiti, predstavljaju atom vodonika, halogena, poželjno hlora ili broma alkil grupa sa 1-4 C-atoma, alkoksi grupu sa 1-4 C-atoma u alkil delu, nitro ili cijano grupu; R2 predstavlja atom vodonika, halogena, alkoksi radikal u kome alkil deo sadrži 1-4 C-atoma, alkil grupu sa 1-4 C-atoma, fenil grupu, fenilalkil grupu u kojoj alkil deo ima 1-4 C-atoma, ili alkilen fenil u kome alkilen radikal ima 2-4 C-atoma, nitro ili cijano grupu; R3 predstavlja atom vodonika, alkil grupu sa 1-3 C-atoma; i njihovih soli, naznačen time, što se jedinjenje formule u kojoj R, R1, R2 i R3 imaju gore data značenja, tretira sa tionilbismidazolom formule u podesnom organskom rastvaraču; ili se trasformiše u odgovarajući halogeni derivat dejstvom podesnog sredstva za halogenovanje i posle toga se tako dobijeni intermedijarni halogeni derivat tretira imidazolom, i kao slobodni i u obliku soli, u organskom rastvaraču, poželjno polarne prirode i na temperaturi ključanja, i posle toga, ako se želi, tako dobijeno jedinjenje prevodi u svoju kiselinsku adicionu so.
YU150787A 1986-08-13 1987-08-13 Postupak za dobijanje novih (benzofuran-2-il)imidazola YU46222B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8609461A IT1216256B (it) 1986-08-13 1986-08-13 (benzofuran-2-il) imidazoli, con attivita' farmacologica,loro sali e procedimenti di fabbricazione relativi.

Publications (2)

Publication Number Publication Date
YU150787A YU150787A (en) 1988-10-31
YU46222B true YU46222B (sh) 1993-05-28

Family

ID=11130481

Family Applications (1)

Application Number Title Priority Date Filing Date
YU150787A YU46222B (sh) 1986-08-13 1987-08-13 Postupak za dobijanje novih (benzofuran-2-il)imidazola

Country Status (23)

Country Link
US (1) US4800208A (sh)
EP (1) EP0257171B1 (sh)
JP (1) JPS6372687A (sh)
AR (1) AR243181A1 (sh)
AT (1) ATE56008T1 (sh)
AU (1) AU604042B2 (sh)
CA (1) CA1325212C (sh)
CS (1) CS272226B2 (sh)
DD (1) DD270305A5 (sh)
DE (1) DE3673822D1 (sh)
DK (1) DK166917B1 (sh)
ES (1) ES2037011T3 (sh)
GR (1) GR3000903T3 (sh)
HU (1) HU202864B (sh)
IE (1) IE61019B1 (sh)
IT (1) IT1216256B (sh)
MX (1) MX7723A (sh)
NO (1) NO170085C (sh)
PL (1) PL149009B1 (sh)
PT (1) PT85491B (sh)
SU (1) SU1600630A3 (sh)
YU (1) YU46222B (sh)
ZA (1) ZA875908B (sh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0574992A1 (en) * 1992-06-17 1993-12-22 Glaxo Group Limited 5-(1,2,4-Triazol-1-ylmethyl)-3H-isobenzofuran-1-one derivatives, their preparation and use as aromatase inhibitors
GB9212833D0 (en) * 1992-06-17 1992-07-29 Glaxo Group Ltd Chemical compounds
US5426196A (en) * 1993-12-22 1995-06-20 Glaxo Inc. Synthesis of diaryl methanes
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
US6503935B1 (en) 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
GB0223915D0 (en) * 2002-10-15 2002-11-20 Univ Cardiff Benzofuran derivatives formulations and uses thereof
CA2652280C (en) 2006-05-15 2014-01-28 Massachusetts Institute Of Technology Polymers for functional particles
JP2011500569A (ja) 2007-10-12 2011-01-06 マサチューセッツ インスティテュート オブ テクノロジー ワクチンナノテクノロジー
US7762049B2 (en) 2008-12-31 2010-07-27 Black & Decker Inc. Electric mower having two-motion activation system
CN112063532B (zh) * 2020-08-11 2022-05-24 浙江工业大学 林生地霉及其制备(s)-1-(2-三氟甲基苯基)乙醇的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6915465D0 (pt) * 1969-03-07 1973-01-04 Bayer Ag Processo para preparar n-benzimidazois substituidos na posicao alfa por heterociclos penta-membrados com atividade antimicotica
DE2009020C3 (de) * 1970-02-26 1979-09-13 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von N-(l,l,l-trisubstituierten)-Methylazolen
US3928348A (en) * 1970-03-23 1975-12-23 Bayer Ag N-methyl-imidazole derivatives and their production
IT1154888B (it) * 1980-11-12 1987-01-21 Menarini Sas Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione
DE3049542A1 (de) * 1980-12-31 1982-07-29 Basf Ag, 6700 Ludwigshafen Azolylalkyl-2,3-dihydrobenzofurane, diese enthaltende fungizide und verfahren zu ihrer herstellung
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
FI842502A (fi) * 1983-06-27 1984-12-28 Ciba Geigy Ag Foerfarande foer framstaellning av nya 2-substituerade bensofuran derivat.
DE3413363A1 (de) * 1984-04-09 1985-10-17 Merz + Co GmbH & Co, 6000 Frankfurt Benzofuran-2-yl-ethyl-imidazolderivate, verfahren zu ihrer herstellung und pharmazeutische mittel

Also Published As

Publication number Publication date
HUT46910A (en) 1988-12-28
ZA875908B (en) 1988-02-12
EP0257171A1 (en) 1988-03-02
CS597887A2 (en) 1990-03-14
AU604042B2 (en) 1990-12-06
SU1600630A3 (ru) 1990-10-15
PT85491B (pt) 1990-06-29
CS272226B2 (en) 1991-01-15
HU202864B (en) 1991-04-29
EP0257171B1 (en) 1990-08-29
DK166917B1 (da) 1993-08-02
PL267298A1 (en) 1988-12-08
DD270305A5 (de) 1989-07-26
IE61019B1 (en) 1994-09-07
NO170085C (no) 1992-09-09
PT85491A (en) 1987-09-01
GR3000903T3 (en) 1991-12-10
IT8609461A0 (it) 1986-08-13
DE3673822D1 (de) 1990-10-04
MX7723A (es) 1993-12-01
PL149009B1 (en) 1989-12-30
AU7679987A (en) 1988-02-18
ATE56008T1 (de) 1990-09-15
IE872153L (en) 1988-02-13
DK418187A (da) 1988-02-14
NO873383L (no) 1988-02-15
YU150787A (en) 1988-10-31
JPS6372687A (ja) 1988-04-02
IT1216256B (it) 1990-02-22
NO873383D0 (no) 1987-08-12
US4800208A (en) 1989-01-24
AR243181A1 (es) 1993-07-30
CA1325212C (en) 1993-12-14
DK418187D0 (da) 1987-08-11
NO170085B (no) 1992-06-01
ES2037011T3 (es) 1993-06-16

Similar Documents

Publication Publication Date Title
DE69021502T2 (de) Benzimidazolderivate, Verfahren zu deren Herstellung und Anwendung.
SE8201145L (sv) Nya aminometyl-5 oxazolidiniska derivat, deras framstellningssett och derasterapeutiska anvendning
KR880001651A (ko) 이미다조 [4,5-b] 피리딘 유도체, 그의 제조방법 및 그를 함유하는 항궤양제
IL67744A0 (en) N-phenylsulfonyl-n'-pyrimidinyl-and n'-triazinylureas,their preparation and the use as herbicides and plant growth regulants
YU46222B (sh) Postupak za dobijanje novih (benzofuran-2-il)imidazola
EA199800759A1 (ru) 2-гетароилциклогексан-1,3-дионы
KR870002056A (ko) 치환된 프로파르길옥시아세토니트릴 유도체의 제조 방법
KR850004483A (ko) 치환된 2-피리딜메틸-티오 및 -설피닐 벤즈이미다졸의 제조방법
IT1264563B1 (it) Composti fotocromatici e metodo per la loro preparazione
KR840004345A (ko) 피라졸 유도체 및 그것의 제조방법과 유효성분으로서 그것을 함유하는 선택적인 제초조성물, 그리고 그것을 사용하여 잡초를 제거하고 억제하는 방법.
SE7710873L (sv) Nya 1h-pyrazolo(3,4-b)pyridiner
SE7714940L (sv) Forfarande for framstellning av nya derivat av 4,5,6,7-tetrahydrotieno (2,3-c) - och (3,2-c) pyridin
NZ212156A (en) Substituted imidazoles and triazoles and microbicidal compositions
KR860007251A (ko) 트리아졸 유도체의 제조방법
PT81556B (pt) Processo para a preparacao de agentes anti-fungicos de triazole
YU48331B (sh) Postupak za dobijanje triazolil-izopropanola
KR840008357A (ko) 4-페닐-테트라히드로-푸라노[2,3-c]피리딘 및 이의 산 부가염의 제조방법
KR870008860A (ko) 설포닐 아졸 및 그의 제조방법
ES8307766A1 (es) Procedimiento para la preparacion de derivados de azolil-penteno.
YU48037B (sh) POSTUPAK ZA DOBIJANJE NOVIH ENOLETARA 1,1-DIOKSIDA AMIDA 6-HLOR-4-HIDROKSI-2-METIL-n-(2-PIRIDIL)-2H-TIENO(2,3-e)-1,2 -TIAZIN-3-KARBOKSILNE KISELINE
ATE9899T1 (de) Pyridinderivate, ihre herstellung und verwendung.
ATE102610T1 (de) Imidazolderivate, verfahren zu deren herstellung und diese enthaltende antiulkusmittel.
MX5687E (es) Procedimiento para la preparacion de derivados imidazo(1,2-alpha)-imidazol substituidos
ATE39687T1 (de) Verfahren zur herstellung von keten-o,n-acetalen.
DK82583A (da) Furyloxazolyleddikesyrederivater og fremgangsmaader til fremstilling deraf