YU46156B - Sredstvo koje u rastvaraču emituje biološki aktivnu supstancu konstantnom brzinom - Google Patents

Sredstvo koje u rastvaraču emituje biološki aktivnu supstancu konstantnom brzinom

Info

Publication number
YU46156B
YU46156B YU121485A YU121485A YU46156B YU 46156 B YU46156 B YU 46156B YU 121485 A YU121485 A YU 121485A YU 121485 A YU121485 A YU 121485A YU 46156 B YU46156 B YU 46156B
Authority
YU
Yugoslavia
Prior art keywords
solvent
active substance
biologically active
membrane
emisses
Prior art date
Application number
YU121485A
Other languages
English (en)
Other versions
YU121485A (en
Inventor
P. Colombo
U. Conte
A. Reiner
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of YU121485A publication Critical patent/YU121485A/xx
Publication of YU46156B publication Critical patent/YU46156B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Abstract

naznačena time, što je čvrsta porozna matrica (1A, 1B) homogeni polimerni materijal nerastvorljiv u rastvaraču i u količini od 3-20 mas.%, što je 5-50 mas.% rastvora aditiv sa negativnom toplotom rastvaranja i 30-90 mas.% je biološki aktivna supstanca koja je sa aditivom dispergovana u porama matrice (1A, 1B) koju okružuje obloga membrane (2A, 2B) i (3A, 3B), gde membrana (2A, 2B) je polimerni film, homogen i nerastvoran za rastvarač od oko 0.04 - 0.01 mm, najpogodnije 4-8 mg/cm2, a membrana (3A, 3B) je polimer rastvoran u rastvaraču i obavija membranu (2A, 2B). Prijava sadrži još 5 patentnih zahteva.
YU121485A 1984-07-26 1985-07-24 Sredstvo koje u rastvaraču emituje biološki aktivnu supstancu konstantnom brzinom YU46156B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8448632A IT1206166B (it) 1984-07-26 1984-07-26 Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione

Publications (2)

Publication Number Publication Date
YU121485A YU121485A (en) 1990-12-31
YU46156B true YU46156B (sh) 1993-05-28

Family

ID=11267748

Family Applications (1)

Application Number Title Priority Date Filing Date
YU121485A YU46156B (sh) 1984-07-26 1985-07-24 Sredstvo koje u rastvaraču emituje biološki aktivnu supstancu konstantnom brzinom

Country Status (23)

Country Link
US (1) US4681755A (sh)
EP (1) EP0169821B1 (sh)
JP (1) JPS6143109A (sh)
KR (1) KR920005808B1 (sh)
AT (1) ATE60709T1 (sh)
AU (1) AU578299B2 (sh)
BR (1) BR8503539A (sh)
DE (1) DE3581673D1 (sh)
DK (1) DK166992B1 (sh)
ES (1) ES8801123A1 (sh)
FI (1) FI86372C (sh)
GR (1) GR851844B (sh)
IE (1) IE58120B1 (sh)
IL (1) IL75915A (sh)
IN (1) IN162047B (sh)
IT (1) IT1206166B (sh)
MX (1) MX173488B (sh)
NO (1) NO171004C (sh)
PH (1) PH22507A (sh)
PT (1) PT80865B (sh)
TR (1) TR23019A (sh)
YU (1) YU46156B (sh)
ZA (1) ZA855553B (sh)

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DE3686275T2 (de) * 1985-01-11 1993-03-18 Teijin Ltd Praeparate mit verzoegerter freisetzung.
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
SE450087B (sv) * 1985-10-11 1987-06-09 Haessle Ab Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
US4898733A (en) * 1985-11-04 1990-02-06 International Minerals & Chemical Corp. Layered, compression molded device for the sustained release of a beneficial agent
US4775536A (en) * 1986-02-24 1988-10-04 Bristol-Myers Company Enteric coated tablet and process for making
US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
SE8703881D0 (sv) * 1987-10-08 1987-10-08 Haessle Ab New pharmaceutical preparation
US5219621A (en) * 1987-10-16 1993-06-15 Elan Corporation, Plc Methods of treatment with diltiazem formulations
IL88083A (en) * 1987-11-06 1992-11-15 Tanabe Seiyaku Co Controlled release pharmaceutical dosage form and its preparation
US4859470A (en) * 1988-06-02 1989-08-22 Alza Corporation Dosage form for delivering diltiazem
US4931287A (en) * 1988-06-14 1990-06-05 University Of Utah Heterogeneous interpenetrating polymer networks for the controlled release of drugs
GR1000503B (el) * 1988-12-07 1992-07-30 Ferring Bv Μεθοδος και συσκευη χρησιμη για την παροχη ιατρικων συνθεσεων στην κυστη και στην ουροποιητικη οδο.
FR2640876B1 (sh) * 1988-12-28 1993-09-24 Jouveinal Sa
US4983399A (en) * 1989-10-18 1991-01-08 Eastman Kodak Company Direct compression carrier composition
US5378475A (en) * 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5407686A (en) * 1991-11-27 1995-04-18 Sidmak Laboratories, Inc. Sustained release composition for oral administration of active ingredient
US20030170290A1 (en) * 1993-06-16 2003-09-11 Shug Austin L. Delayed release carnitine
WO1995005168A1 (en) * 1993-08-19 1995-02-23 Shug Austin L Delayed release carnitine
US5783212A (en) * 1996-02-02 1998-07-21 Temple University--of the Commonwealth System of Higher Education Controlled release drug delivery system
US5902598A (en) * 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
US6337091B1 (en) 1997-10-27 2002-01-08 Temple University - Of The Commonwealth System Of Higher Education Matrix for controlled delivery of highly soluble pharmaceutical agents
FR2772615B1 (fr) 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
US20040121014A1 (en) * 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
ITMI20012481A1 (it) * 2001-11-23 2003-05-23 Univ Parma Sistemi modulari per il rilascio controllato di sostanza a controllo spaziale e temporale
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US6986901B2 (en) * 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
CA2491797A1 (en) * 2002-07-10 2004-01-22 Warner-Lambert Company Llc Gastrointestinal compositions
US20040010035A1 (en) * 2002-07-15 2004-01-15 Ciociola Arthur A. Gastrointestinal compositions
US7063862B2 (en) * 2003-06-03 2006-06-20 Biokey, Inc. Pharmaceutical composition and method for treating
US20060024368A1 (en) * 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
US8128460B2 (en) * 2006-09-14 2012-03-06 The Material Works, Ltd. Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell
CN101863942B (zh) * 2009-04-14 2013-05-22 北京赛而生物药业有限公司 一种异丙肌苷的制备方法及其口服制剂
US20110238036A1 (en) * 2009-12-23 2011-09-29 Psivida Us, Inc. Sustained release delivery devices
JP4877538B2 (ja) * 2010-06-08 2012-02-15 東洋製罐株式会社 シームレス缶体

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Also Published As

Publication number Publication date
NO171004B (no) 1992-10-05
BR8503539A (pt) 1986-04-22
PT80865B (pt) 1987-09-18
FI852894A0 (fi) 1985-07-25
TR23019A (tr) 1989-01-23
IN162047B (sh) 1988-03-19
DK339385D0 (da) 1985-07-25
IL75915A (en) 1988-09-30
DE3581673D1 (de) 1991-03-14
IE58120B1 (en) 1993-07-14
FI852894L (fi) 1986-01-27
NO171004C (no) 1993-01-13
EP0169821B1 (en) 1991-02-06
PT80865A (en) 1985-08-01
IT1206166B (it) 1989-04-14
AU578299B2 (en) 1988-10-20
MX173488B (es) 1994-03-08
IL75915A0 (en) 1985-12-31
FI86372B (fi) 1992-05-15
KR860000800A (ko) 1986-02-20
US4681755A (en) 1987-07-21
PH22507A (en) 1988-09-12
ZA855553B (en) 1986-03-26
YU121485A (en) 1990-12-31
DK166992B1 (da) 1993-08-16
FI86372C (fi) 1992-08-25
ES545679A0 (es) 1987-12-16
DK339385A (da) 1986-01-27
EP0169821A3 (en) 1987-05-06
ATE60709T1 (de) 1991-02-15
GR851844B (sh) 1985-12-02
IT8448632A0 (it) 1984-07-26
KR920005808B1 (ko) 1992-07-20
AU4525185A (en) 1986-01-30
ES8801123A1 (es) 1987-12-16
JPS6143109A (ja) 1986-03-01
EP0169821A2 (en) 1986-01-29
IE851796L (en) 1986-01-26
NO852966L (no) 1986-01-27

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