ES8801123A1 - Procedimiento para producir un comprimido de dispensacion de un principio biologicamente activo. - Google Patents
Procedimiento para producir un comprimido de dispensacion de un principio biologicamente activo.Info
- Publication number
- ES8801123A1 ES8801123A1 ES545679A ES545679A ES8801123A1 ES 8801123 A1 ES8801123 A1 ES 8801123A1 ES 545679 A ES545679 A ES 545679A ES 545679 A ES545679 A ES 545679A ES 8801123 A1 ES8801123 A1 ES 8801123A1
- Authority
- ES
- Spain
- Prior art keywords
- active principle
- dissolution fluid
- zero
- delivery device
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Lubricants (AREA)
Abstract
METODO DE PREPARACION DE COMPRIMIDOS DE LIBERACION CONTROLADA DE PRINCIPIOS BIOLOGICAMENTE ACTIVOS. CONSISTE EN PREPARAR UNA MEZCLA CONSTITUIDA POR UNA MATRIZ SOLIDA POROSA DE MATERIAL POLIMERO HOMOGENEO INSOLUBLE EN EL MEDIO E HINCHABLE, UN ADITIVO SOLUBLE EN EL MEDIO, CUYO CALOR DE DISOLUCION ES NEGATIVO, EL INGREDIENTE BIOLOGICAMENTE ACTIVO, UN PRIMER REVESTIMIENTO, HOMOGENEO Y CONTINUO DE UN POLIMERO FILMOGENO, INSOLUBLE EN EL MEDIO Y UN SEGUNDO REVESTIMIENTO DE IGUALES CARACTERISTICAS PERO SOLUBLE EN EL MEDIO; GRANULAR LA MEZCLA CON UN TAMAÑO DE GRANO INFERIOR A 420 MICRAS, SECAR, AÑADIR UN LUBRICANTE, COMPRIMIR Y APLICAR LA MEMBRANA CONTROLADORA DEL RITMO DE LIBERACION POR CONTACTO CON EL PRIMER POLIMERO FILMOGENO; FINALMENTE, APLICAR EL SEGUNDO POLIMERO FILMOGENO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8448632A IT1206166B (it) | 1984-07-26 | 1984-07-26 | Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione |
Publications (2)
Publication Number | Publication Date |
---|---|
ES545679A0 ES545679A0 (es) | 1987-12-16 |
ES8801123A1 true ES8801123A1 (es) | 1987-12-16 |
Family
ID=11267748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES545679A Expired ES8801123A1 (es) | 1984-07-26 | 1985-07-24 | Procedimiento para producir un comprimido de dispensacion de un principio biologicamente activo. |
Country Status (23)
Country | Link |
---|---|
US (1) | US4681755A (es) |
EP (1) | EP0169821B1 (es) |
JP (1) | JPS6143109A (es) |
KR (1) | KR920005808B1 (es) |
AT (1) | ATE60709T1 (es) |
AU (1) | AU578299B2 (es) |
BR (1) | BR8503539A (es) |
DE (1) | DE3581673D1 (es) |
DK (1) | DK166992B1 (es) |
ES (1) | ES8801123A1 (es) |
FI (1) | FI86372C (es) |
GR (1) | GR851844B (es) |
IE (1) | IE58120B1 (es) |
IL (1) | IL75915A (es) |
IN (1) | IN162047B (es) |
IT (1) | IT1206166B (es) |
MX (1) | MX173488B (es) |
NO (1) | NO171004C (es) |
PH (1) | PH22507A (es) |
PT (1) | PT80865B (es) |
TR (1) | TR23019A (es) |
YU (1) | YU46156B (es) |
ZA (1) | ZA855553B (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3686275T2 (de) * | 1985-01-11 | 1993-03-18 | Teijin Ltd | Praeparate mit verzoegerter freisetzung. |
DE3505433A1 (de) * | 1985-02-16 | 1986-08-21 | Basf Ag, 6700 Ludwigshafen | Direkttablettierhilfsmittel |
SE450087B (sv) * | 1985-10-11 | 1987-06-09 | Haessle Ab | Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial |
SE455836B (sv) * | 1985-10-11 | 1988-08-15 | Haessle Ab | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
US4898733A (en) * | 1985-11-04 | 1990-02-06 | International Minerals & Chemical Corp. | Layered, compression molded device for the sustained release of a beneficial agent |
US4775536A (en) * | 1986-02-24 | 1988-10-04 | Bristol-Myers Company | Enteric coated tablet and process for making |
US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
US5219621A (en) * | 1987-10-16 | 1993-06-15 | Elan Corporation, Plc | Methods of treatment with diltiazem formulations |
IL88083A (en) * | 1987-11-06 | 1992-11-15 | Tanabe Seiyaku Co | Controlled release pharmaceutical dosage form and its preparation |
US4859470A (en) * | 1988-06-02 | 1989-08-22 | Alza Corporation | Dosage form for delivering diltiazem |
US4931287A (en) * | 1988-06-14 | 1990-06-05 | University Of Utah | Heterogeneous interpenetrating polymer networks for the controlled release of drugs |
GR1000503B (el) * | 1988-12-07 | 1992-07-30 | Ferring Bv | Μεθοδος και συσκευη χρησιμη για την παροχη ιατρικων συνθεσεων στην κυστη και στην ουροποιητικη οδο. |
FR2640876B1 (es) * | 1988-12-28 | 1993-09-24 | Jouveinal Sa | |
US4983399A (en) * | 1989-10-18 | 1991-01-08 | Eastman Kodak Company | Direct compression carrier composition |
US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
US5407686A (en) * | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
US20030170290A1 (en) * | 1993-06-16 | 2003-09-11 | Shug Austin L. | Delayed release carnitine |
WO1995005168A1 (en) * | 1993-08-19 | 1995-02-23 | Shug Austin L | Delayed release carnitine |
US5783212A (en) * | 1996-02-02 | 1998-07-21 | Temple University--of the Commonwealth System of Higher Education | Controlled release drug delivery system |
US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
US6342611B1 (en) * | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
US6337091B1 (en) | 1997-10-27 | 2002-01-08 | Temple University - Of The Commonwealth System Of Higher Education | Matrix for controlled delivery of highly soluble pharmaceutical agents |
FR2772615B1 (fr) | 1997-12-23 | 2002-06-14 | Lipha | Comprime multicouche pour la liberation instantanee puis prolongee de substances actives |
SA99191255B1 (ar) | 1998-11-30 | 2006-11-25 | جي دي سيرل اند كو | مركبات سيليكوكسيب celecoxib |
US20040121014A1 (en) * | 1999-03-22 | 2004-06-24 | Control Delivery Systems, Inc. | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
US6217895B1 (en) * | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
ITMI20012481A1 (it) | 2001-11-23 | 2003-05-23 | Univ Parma | Sistemi modulari per il rilascio controllato di sostanza a controllo spaziale e temporale |
US8871241B2 (en) | 2002-05-07 | 2014-10-28 | Psivida Us, Inc. | Injectable sustained release delivery devices |
JP2005533101A (ja) * | 2002-07-10 | 2005-11-04 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | アロステリック阻害剤又はマトリックス金属タンパク質分解酵素−13の、セレコキシブでもバルデコキシブでもないシクロオキシゲナーゼ−2の選択的阻害剤との組合せ物 |
US6986901B2 (en) * | 2002-07-15 | 2006-01-17 | Warner-Lambert Company Llc | Gastrointestinal compositions |
US20040010035A1 (en) * | 2002-07-15 | 2004-01-15 | Ciociola Arthur A. | Gastrointestinal compositions |
US7063862B2 (en) * | 2003-06-03 | 2006-06-20 | Biokey, Inc. | Pharmaceutical composition and method for treating |
US20060024368A1 (en) * | 2004-07-30 | 2006-02-02 | Reza Fassihi | Compressed composite delivery system for release-rate modulation of bioactives |
US8128460B2 (en) * | 2006-09-14 | 2012-03-06 | The Material Works, Ltd. | Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell |
CN101863942B (zh) * | 2009-04-14 | 2013-05-22 | 北京赛而生物药业有限公司 | 一种异丙肌苷的制备方法及其口服制剂 |
EP2515864A4 (en) * | 2009-12-23 | 2013-09-11 | Psivida Inc | DELAYED RELEASE DELIVERY DEVICES |
JP4877538B2 (ja) * | 2010-06-08 | 2012-02-15 | 東洋製罐株式会社 | シームレス缶体 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3275519A (en) * | 1965-10-01 | 1966-09-27 | Jacob A Glassman | Peroral pellet and the method of making same |
US3577512A (en) * | 1968-10-11 | 1971-05-04 | Nat Patent Dev Corp | Sustained release tablets |
US3832252A (en) * | 1970-09-29 | 1974-08-27 | T Higuchi | Method of making a drug-delivery device |
US4118336A (en) * | 1974-03-25 | 1978-10-03 | Toyo Jozo Company, Ltd. | Novel cellulose microcapsules and preparation thereof |
US4140756A (en) * | 1976-06-10 | 1979-02-20 | Mead Johnson & Company | Film-coated matrix core tablet |
US4180560A (en) * | 1976-10-26 | 1979-12-25 | Syntex Corporation | Inert core implant pellet |
US4218433A (en) * | 1977-03-03 | 1980-08-19 | Nippon Kayaku Kabushiki Kaisha | Constant-rate eluting tablet and method of producing same |
US4173626A (en) * | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
US4309405A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
FR2471186A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
DE3013059A1 (de) * | 1980-04-03 | 1981-10-08 | Sandoz-Patent-GmbH, 7850 Lörrach | Neue galenische zusammensetzung |
JPS5835110A (ja) * | 1981-08-28 | 1983-03-01 | Tetsuo Kato | 徐放性マイクロカプセル |
IT1153487B (it) * | 1982-04-15 | 1987-01-14 | Prophin Lab Spa | Prodotti farmaceutici in forma-ritardo e procedimento per ottenerli |
US4557925A (en) * | 1982-07-08 | 1985-12-10 | Ab Ferrosan | Membrane-coated sustained-release tablets and method |
US4505890A (en) * | 1983-06-30 | 1985-03-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation and method |
US4539198A (en) * | 1983-07-07 | 1985-09-03 | Rowell Laboratories, Inc. | Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range |
-
1984
- 1984-07-26 IT IT8448632A patent/IT1206166B/it active
-
1985
- 1985-07-16 AT AT85830182T patent/ATE60709T1/de not_active IP Right Cessation
- 1985-07-16 DE DE8585830182T patent/DE3581673D1/de not_active Expired - Fee Related
- 1985-07-16 EP EP85830182A patent/EP0169821B1/en not_active Expired - Lifetime
- 1985-07-17 IE IE179685A patent/IE58120B1/en not_active IP Right Cessation
- 1985-07-18 IN IN555/MAS/85A patent/IN162047B/en unknown
- 1985-07-19 KR KR1019850005159A patent/KR920005808B1/ko not_active IP Right Cessation
- 1985-07-22 US US06/757,601 patent/US4681755A/en not_active Expired - Fee Related
- 1985-07-23 AU AU45251/85A patent/AU578299B2/en not_active Ceased
- 1985-07-23 ZA ZA855553A patent/ZA855553B/xx unknown
- 1985-07-24 JP JP60163777A patent/JPS6143109A/ja active Pending
- 1985-07-24 YU YU121485A patent/YU46156B/sh unknown
- 1985-07-24 TR TR33231/85A patent/TR23019A/xx unknown
- 1985-07-24 ES ES545679A patent/ES8801123A1/es not_active Expired
- 1985-07-25 NO NO852966A patent/NO171004C/no unknown
- 1985-07-25 IL IL75915A patent/IL75915A/xx not_active IP Right Cessation
- 1985-07-25 PH PH32566A patent/PH22507A/en unknown
- 1985-07-25 PT PT80865A patent/PT80865B/pt unknown
- 1985-07-25 FI FI852894A patent/FI86372C/fi not_active IP Right Cessation
- 1985-07-25 BR BR8503539A patent/BR8503539A/pt not_active IP Right Cessation
- 1985-07-25 DK DK339385A patent/DK166992B1/da not_active IP Right Cessation
- 1985-07-25 GR GR851844A patent/GR851844B/el unknown
- 1985-07-25 MX MX206098A patent/MX173488B/es unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |