YU45607B - Postupak za dobijanje pirimidintrionskih derivata - Google Patents
Postupak za dobijanje pirimidintrionskih derivataInfo
- Publication number
- YU45607B YU45607B YU66484A YU66484A YU45607B YU 45607 B YU45607 B YU 45607B YU 66484 A YU66484 A YU 66484A YU 66484 A YU66484 A YU 66484A YU 45607 B YU45607 B YU 45607B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- formula
- group
- alkyl group
- temperature
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
Abstract
POSTUPAK ZA DOBIJANJE PIRIMIDINTRIONSKIH DERIVATA, formule (I): u kojoj R1 i R2 koji mogu biti isti ili različiti, predstavljaju C1-5 alkil grupu, C2-5 alkenil grupu, aralkil grupu u kojoj svaka alkil grupa sadrži 1-4 ugljenikova atoma ili karbocikličnu aril grupu, i R3 predstavlja grupu formule -CH2CH(OCONH2)CH2OX, gde je X vodonik ili C1-5 alkil grupa, naznačen time, što obuhvata reakciju približno ekvimolarnih količina natrijumove soli jedinjenja formule (I) u kome je R3 atom vodonika, sa sredstvom za alkilovanje formule R3Hal, gde je R3 definisano kao gore, a Hal predstavlja atom halogena, na povišenoj temperaturi, kao što je temperatura reaktanata, u prisustvu najmanje 0.2 mola kiseline formule (I) gde je R3 atom vodonika na mol natrijumove soli. Postupak prema zahtevima 1-3, na značen time, što se reakcija izvodi u rastopu na temperaturi od 100-110 C. Postupak prema zahtevu 1, naznačen time, što se R1 i R2 svaki posebno biraju medju etil, propil, izopentil, alil, benzil i fenil grupama. Prijava sadrži još 3 patentna zahteva.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838309813A GB8309813D0 (en) | 1983-04-12 | 1983-04-12 | Pyrimidinetrione derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
YU66484A YU66484A (en) | 1986-12-31 |
YU45607B true YU45607B (sh) | 1992-07-20 |
Family
ID=10540932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU66484A YU45607B (sh) | 1983-04-12 | 1984-04-11 | Postupak za dobijanje pirimidintrionskih derivata |
Country Status (39)
Country | Link |
---|---|
US (1) | US4611057A (sh) |
EP (1) | EP0125046B1 (sh) |
JP (1) | JPS59205370A (sh) |
AR (1) | AR240317A1 (sh) |
AT (1) | AT388917B (sh) |
AU (1) | AU554056B2 (sh) |
BE (1) | BE899385A (sh) |
BG (1) | BG65031A (sh) |
BR (1) | BR8401679A (sh) |
CA (1) | CA1247619A (sh) |
CH (1) | CH658653A5 (sh) |
CS (1) | CS276389B6 (sh) |
DD (1) | DD222018A5 (sh) |
DE (1) | DE3464910D1 (sh) |
DK (1) | DK158726C (sh) |
EG (1) | EG17794A (sh) |
ES (1) | ES531498A0 (sh) |
FI (1) | FI84348C (sh) |
FR (1) | FR2544312B1 (sh) |
GB (1) | GB8309813D0 (sh) |
GR (1) | GR79890B (sh) |
HU (1) | HU192548B (sh) |
IE (1) | IE57321B1 (sh) |
IL (1) | IL71515A (sh) |
IN (1) | IN161291B (sh) |
IT (1) | IT1177658B (sh) |
LU (1) | LU85296A1 (sh) |
MA (1) | MA20092A1 (sh) |
MX (1) | MX159632A (sh) |
NO (1) | NO170928C (sh) |
NZ (1) | NZ207802A (sh) |
PH (1) | PH24131A (sh) |
PL (1) | PL144481B1 (sh) |
PT (1) | PT78400B (sh) |
RO (1) | RO89141A (sh) |
SU (1) | SU1380611A3 (sh) |
UA (1) | UA7040A1 (sh) |
YU (1) | YU45607B (sh) |
ZA (1) | ZA842687B (sh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9002890D0 (en) * | 1990-02-08 | 1990-04-04 | Sapos Sa | Process for preparing pyrimidinetrione derivatives |
JPH0436236A (ja) * | 1990-05-30 | 1992-02-06 | Mitsui Pharmaceut Inc | 脳神経障害及び脳循環代謝障害の改善治療剤 |
RU2141322C1 (ru) * | 1997-08-12 | 1999-11-20 | Голощапов Николай Михайлович | Иммуномодулятор с антимикобактериальной активностью "изофон", способ его получения и применения |
WO1999061427A1 (fr) * | 1998-05-26 | 1999-12-02 | Rimma Iliinichna Ashkinazi | Derives n-substitues d'acide 5-oxyiminobarbiturique |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3075983A (en) * | 1963-01-29 | -oconh | ||
CA873891A (en) * | 1971-06-22 | Melkonian Diran | Barbituric acid derivatives | |
GB1193438A (en) * | 1966-10-26 | 1970-06-03 | Phillipe Gold-Aubert | Barbituric Acid Derivatives, preparation thereof and Pharmaceutical Compositions containing them |
GB1581834A (en) * | 1976-11-01 | 1980-12-31 | Sapos Sa | Complexes of barbituric acid derivatives |
FR2424262A1 (fr) * | 1978-04-24 | 1979-11-23 | Sapos Sa | Nouveaux complexes tetrameres de derives de la malonyl-uree a action psychotrope et procede de preparation |
-
1983
- 1983-04-12 GB GB838309813A patent/GB8309813D0/en active Pending
-
1984
- 1984-04-11 DE DE8484302489T patent/DE3464910D1/de not_active Expired
- 1984-04-11 NO NO841438A patent/NO170928C/no unknown
- 1984-04-11 EG EG238/84A patent/EG17794A/xx active
- 1984-04-11 IT IT48019/84A patent/IT1177658B/it active
- 1984-04-11 US US06/598,969 patent/US4611057A/en not_active Expired - Fee Related
- 1984-04-11 FR FR8405750A patent/FR2544312B1/fr not_active Expired
- 1984-04-11 AT AT0122084A patent/AT388917B/de not_active IP Right Cessation
- 1984-04-11 AU AU26749/84A patent/AU554056B2/en not_active Ceased
- 1984-04-11 MA MA20313A patent/MA20092A1/fr unknown
- 1984-04-11 CS CS842762A patent/CS276389B6/cs unknown
- 1984-04-11 IE IE890/84A patent/IE57321B1/en not_active IP Right Cessation
- 1984-04-11 YU YU66484A patent/YU45607B/sh unknown
- 1984-04-11 CH CH1826/84A patent/CH658653A5/de not_active IP Right Cessation
- 1984-04-11 ES ES531498A patent/ES531498A0/es active Granted
- 1984-04-11 IN IN318/DEL/84A patent/IN161291B/en unknown
- 1984-04-11 ZA ZA842687A patent/ZA842687B/xx unknown
- 1984-04-11 SU SU843723552A patent/SU1380611A3/ru active
- 1984-04-11 FI FI841430A patent/FI84348C/fi not_active IP Right Cessation
- 1984-04-11 CA CA000451688A patent/CA1247619A/en not_active Expired
- 1984-04-11 MX MX8203A patent/MX159632A/es unknown
- 1984-04-11 EP EP84302489A patent/EP0125046B1/en not_active Expired
- 1984-04-11 BG BG65031A patent/BG65031A/xx unknown
- 1984-04-11 NZ NZ207802A patent/NZ207802A/en unknown
- 1984-04-11 RO RO84114230A patent/RO89141A/ro unknown
- 1984-04-11 LU LU85296A patent/LU85296A1/fr unknown
- 1984-04-11 GR GR74381A patent/GR79890B/el unknown
- 1984-04-11 AR AR296253A patent/AR240317A1/es active
- 1984-04-11 JP JP59071048A patent/JPS59205370A/ja active Granted
- 1984-04-11 UA UA3723552A patent/UA7040A1/uk unknown
- 1984-04-11 IL IL71515A patent/IL71515A/xx not_active IP Right Cessation
- 1984-04-11 PT PT78400A patent/PT78400B/pt not_active IP Right Cessation
- 1984-04-11 BE BE0/212734A patent/BE899385A/fr not_active IP Right Cessation
- 1984-04-11 PL PL1984247174A patent/PL144481B1/pl unknown
- 1984-04-11 BR BR8401679A patent/BR8401679A/pt unknown
- 1984-04-11 HU HU841424A patent/HU192548B/hu not_active IP Right Cessation
- 1984-04-11 DD DD84261877A patent/DD222018A5/de not_active IP Right Cessation
- 1984-04-11 DK DK186784A patent/DK158726C/da not_active IP Right Cessation
- 1984-04-12 PH PH30536A patent/PH24131A/en unknown
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