YU43675B - Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acids - Google Patents
Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acidsInfo
- Publication number
- YU43675B YU43675B YU1630/84A YU163084A YU43675B YU 43675 B YU43675 B YU 43675B YU 1630/84 A YU1630/84 A YU 1630/84A YU 163084 A YU163084 A YU 163084A YU 43675 B YU43675 B YU 43675B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- oxo
- radical
- acids
- hydrogen
- lower alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Control Of Motors That Do Not Use Commutators (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8122020A FR2516922A1 (fr) | 1981-11-25 | 1981-11-25 | Acides (oxo-4-4h-(1)-benzopyran-8-yl) alcanoiques, sels et derives, preparation et medicament les contenant |
Publications (2)
Publication Number | Publication Date |
---|---|
YU163084A YU163084A (en) | 1985-03-20 |
YU43675B true YU43675B (en) | 1989-10-31 |
Family
ID=9264332
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2649/82A YU43726B (en) | 1981-11-25 | 1982-11-25 | Process for obtaining (oxo-4-4h(1)benzopyrane-8-yl-alkanic acids |
YU1630/84A YU43675B (en) | 1981-11-25 | 1984-09-21 | Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acids |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU2649/82A YU43726B (en) | 1981-11-25 | 1982-11-25 | Process for obtaining (oxo-4-4h(1)benzopyrane-8-yl-alkanic acids |
Country Status (24)
Country | Link |
---|---|
US (2) | US4602034A (xx) |
EP (1) | EP0080934B1 (xx) |
JP (1) | JPS5896082A (xx) |
AT (1) | ATE31927T1 (xx) |
AU (1) | AU563190B2 (xx) |
CA (1) | CA1213595A (xx) |
CS (1) | CS248035B2 (xx) |
DD (1) | DD204919A5 (xx) |
DE (1) | DE3277970D1 (xx) |
DK (1) | DK164163C (xx) |
ES (1) | ES517637A0 (xx) |
FR (1) | FR2516922A1 (xx) |
HU (1) | HU192112B (xx) |
IE (1) | IE54130B1 (xx) |
IL (1) | IL67291A0 (xx) |
IN (1) | IN158843B (xx) |
MA (1) | MA19650A1 (xx) |
MX (1) | MX173498B (xx) |
NO (1) | NO159169C (xx) |
NZ (1) | NZ202596A (xx) |
OA (1) | OA07257A (xx) |
SU (1) | SU1250171A3 (xx) |
YU (2) | YU43726B (xx) |
ZA (1) | ZA828436B (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2536397A2 (en) * | 1981-11-25 | 1984-05-25 | Lipha | [4-oxo-4H-1-Benzopyran-8-yl]alkanoic acids, their salts and derivatives, their preparation and medicinal products containing them |
DE3311004A1 (de) * | 1983-03-25 | 1984-09-27 | Bayer Ag, 5090 Leverkusen | Chromon- und thiochromon-8-aldehyde, sowie ein verfahren zu ihrer herstellung |
JPS62215581A (ja) * | 1986-03-18 | 1987-09-22 | Koichi Shiyudo | フラボンカルボン酸誘導体 |
IL85554A0 (en) * | 1987-03-02 | 1988-08-31 | Takeda Chemical Industries Ltd | Chromone derivatives |
IL89840A (en) * | 1988-04-06 | 1996-10-31 | Lipha | Substituted flavonoid compounds and salts thereof their preparation and pharmaceutical composition containing them |
USH1427H (en) * | 1988-04-06 | 1995-04-04 | Briet; Phillipe | Substituted flavonoid compounds, their salts, their manufacture and their use in combination with interleukin-2 |
US5116954A (en) * | 1988-04-06 | 1992-05-26 | Lipha, Lyonnaise Industrielle Pharmaceutique | Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety |
US5126129A (en) * | 1988-05-23 | 1992-06-30 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services | Cancer therapy using interleukin-2 and flavone compounds |
JPH04502761A (ja) * | 1989-01-19 | 1992-05-21 | ジ・アップジョン・カンパニー | フッ素化フラボン酢酸 |
US5238954A (en) * | 1989-01-19 | 1993-08-24 | The Upjohn Company | Fluorinated flavone acetic acid |
US5716982A (en) * | 1995-06-07 | 1998-02-10 | Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences | Retinoids and methods of use of same |
US5703130A (en) * | 1995-06-07 | 1997-12-30 | Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences | Chalcone retinoids and methods of use of same |
US5968940A (en) * | 1995-06-08 | 1999-10-19 | Institute Of Materia Medica | Retinoids and methods of use of same |
AU5717400A (en) * | 1999-06-14 | 2001-01-02 | Cancer Research Ventures Limited | Cancer therapy |
AU2001232917A1 (en) | 2000-01-24 | 2001-07-31 | Jozef S. Mruk | Use of flavone 8-acetic acid in vascular and cardiovascular interventions and acute coronary syndromes |
WO2002009700A1 (en) * | 2000-07-28 | 2002-02-07 | Cancer Research Technology Limited | Cancer treatment by combination therapy |
GB0121285D0 (en) * | 2001-09-03 | 2001-10-24 | Cancer Res Ventures Ltd | Anti-cancer combinations |
GB2386836B (en) * | 2002-03-22 | 2006-07-26 | Cancer Res Ventures Ltd | Anti-cancer combinations |
GB2394658A (en) * | 2002-11-01 | 2004-05-05 | Cancer Rec Tech Ltd | Oral anti-cancer composition |
GB0321999D0 (en) * | 2003-09-19 | 2003-10-22 | Cancer Rec Tech Ltd | Anti-cancer combinations |
AU2006283371A1 (en) * | 2005-08-26 | 2007-03-01 | Antisoma Research Limited | Combinations comprising DMXAA for the treatment of cancer |
EP2470174A1 (en) | 2009-08-27 | 2012-07-04 | Merck Patent GmbH | Use of faa and its derivatives in cosmetics and dermatology |
DK2496567T3 (en) | 2009-11-05 | 2017-10-30 | Rhizen Pharmaceuticals S A | PRESENT UNKNOWN BENZOPYRANKINA MODULATORS |
CN103304531A (zh) * | 2013-06-25 | 2013-09-18 | 南方医科大学 | 一种3-芳基黄酮乙酸 |
KR20180120746A (ko) * | 2016-03-11 | 2018-11-06 | 에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨 | 이카리인 및 이카리틴 유도체 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2921070A (en) * | 1957-11-05 | 1960-01-12 | Recordati Lab Farmacologico S | Basic esters of 3-methylflavone-8-carboxylic acid |
US3350411A (en) * | 1963-10-10 | 1967-10-31 | Pharma Seceph S A Soc D Expl C | Process for preparing 3-methylflavone-8-carboxylic acid |
BE757821A (fr) * | 1970-08-01 | 1971-04-01 | Recordati Chem Pharm | Procede de preparation de l'acide 3-propionyl-salicylique et dederives de cet acide |
GB1479518A (en) * | 1973-12-27 | 1977-07-13 | Erba Carlo Spa | 5,6-benzo-ypsilon-pyrone derivatives |
US4148900A (en) * | 1973-12-27 | 1979-04-10 | Carlo Erba S.P.A. | 5:6-Benzo-γ-pyrone derivatives and process for their preparation |
FR2281112A1 (fr) * | 1974-08-05 | 1976-03-05 | Lipha | Nouveau medicament choleretique et anti-inflammatoire |
GB1469823A (en) * | 1974-08-13 | 1977-04-06 | Farma Lepori | Flavone derivatives |
DE2549745A1 (de) * | 1974-11-20 | 1976-05-26 | Lipha | Durch einen chromonylrest substituierte propionsaeuren sowie deren derivate und verwendungen |
-
1981
- 1981-11-25 FR FR8122020A patent/FR2516922A1/fr active Granted
-
1982
- 1982-11-16 ZA ZA828436A patent/ZA828436B/xx unknown
- 1982-11-17 IL IL67291A patent/IL67291A0/xx not_active IP Right Cessation
- 1982-11-18 IE IE2752/82A patent/IE54130B1/en not_active IP Right Cessation
- 1982-11-18 IN IN848/DEL/82A patent/IN158843B/en unknown
- 1982-11-19 AU AU90730/82A patent/AU563190B2/en not_active Ceased
- 1982-11-23 HU HU823764A patent/HU192112B/hu not_active IP Right Cessation
- 1982-11-24 NZ NZ202596A patent/NZ202596A/en unknown
- 1982-11-24 MX MX010425A patent/MX173498B/es unknown
- 1982-11-24 SU SU823516803A patent/SU1250171A3/ru active
- 1982-11-24 ES ES517637A patent/ES517637A0/es active Granted
- 1982-11-24 DE DE8282402137T patent/DE3277970D1/de not_active Expired
- 1982-11-24 MA MA19863A patent/MA19650A1/fr unknown
- 1982-11-24 AT AT82402137T patent/ATE31927T1/de not_active IP Right Cessation
- 1982-11-24 EP EP82402137A patent/EP0080934B1/fr not_active Expired
- 1982-11-24 DK DK523082A patent/DK164163C/da not_active IP Right Cessation
- 1982-11-24 CS CS828426A patent/CS248035B2/cs unknown
- 1982-11-24 NO NO823940A patent/NO159169C/no unknown
- 1982-11-25 YU YU2649/82A patent/YU43726B/xx unknown
- 1982-11-25 CA CA000416354A patent/CA1213595A/fr not_active Expired
- 1982-11-25 DD DD82245217A patent/DD204919A5/de unknown
- 1982-11-25 JP JP57205582A patent/JPS5896082A/ja active Granted
- 1982-11-25 OA OA57850A patent/OA07257A/xx unknown
-
1984
- 1984-09-21 YU YU1630/84A patent/YU43675B/xx unknown
- 1984-11-06 US US06/669,037 patent/US4602034A/en not_active Expired - Fee Related
-
1986
- 1986-05-29 US US06/872,381 patent/US4783533A/en not_active Expired - Fee Related
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