YU43675B - Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acids - Google Patents

Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acids

Info

Publication number
YU43675B
YU43675B YU1630/84A YU163084A YU43675B YU 43675 B YU43675 B YU 43675B YU 1630/84 A YU1630/84 A YU 1630/84A YU 163084 A YU163084 A YU 163084A YU 43675 B YU43675 B YU 43675B
Authority
YU
Yugoslavia
Prior art keywords
oxo
radical
acids
hydrogen
lower alkyl
Prior art date
Application number
YU1630/84A
Other languages
English (en)
Other versions
YU163084A (en
Inventor
P Briet
J J Berthelon
F Collonges
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Publication of YU163084A publication Critical patent/YU163084A/xx
Publication of YU43675B publication Critical patent/YU43675B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
YU1630/84A 1981-11-25 1984-09-21 Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acids YU43675B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8122020A FR2516922A1 (fr) 1981-11-25 1981-11-25 Acides (oxo-4-4h-(1)-benzopyran-8-yl) alcanoiques, sels et derives, preparation et medicament les contenant

Publications (2)

Publication Number Publication Date
YU163084A YU163084A (en) 1985-03-20
YU43675B true YU43675B (en) 1989-10-31

Family

ID=9264332

Family Applications (2)

Application Number Title Priority Date Filing Date
YU2649/82A YU43726B (en) 1981-11-25 1982-11-25 Process for obtaining (oxo-4-4h(1)benzopyrane-8-yl-alkanic acids
YU1630/84A YU43675B (en) 1981-11-25 1984-09-21 Process for obtaining derivatives of (oxo-4-4h(1)benzopyrane-8-yl)alcanic acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU2649/82A YU43726B (en) 1981-11-25 1982-11-25 Process for obtaining (oxo-4-4h(1)benzopyrane-8-yl-alkanic acids

Country Status (24)

Country Link
US (2) US4602034A (xx)
EP (1) EP0080934B1 (xx)
JP (1) JPS5896082A (xx)
AT (1) ATE31927T1 (xx)
AU (1) AU563190B2 (xx)
CA (1) CA1213595A (xx)
CS (1) CS248035B2 (xx)
DD (1) DD204919A5 (xx)
DE (1) DE3277970D1 (xx)
DK (1) DK164163C (xx)
ES (1) ES517637A0 (xx)
FR (1) FR2516922A1 (xx)
HU (1) HU192112B (xx)
IE (1) IE54130B1 (xx)
IL (1) IL67291A0 (xx)
IN (1) IN158843B (xx)
MA (1) MA19650A1 (xx)
MX (1) MX173498B (xx)
NO (1) NO159169C (xx)
NZ (1) NZ202596A (xx)
OA (1) OA07257A (xx)
SU (1) SU1250171A3 (xx)
YU (2) YU43726B (xx)
ZA (1) ZA828436B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2536397A2 (en) * 1981-11-25 1984-05-25 Lipha [4-oxo-4H-1-Benzopyran-8-yl]alkanoic acids, their salts and derivatives, their preparation and medicinal products containing them
DE3311004A1 (de) * 1983-03-25 1984-09-27 Bayer Ag, 5090 Leverkusen Chromon- und thiochromon-8-aldehyde, sowie ein verfahren zu ihrer herstellung
JPS62215581A (ja) * 1986-03-18 1987-09-22 Koichi Shiyudo フラボンカルボン酸誘導体
IL85554A0 (en) * 1987-03-02 1988-08-31 Takeda Chemical Industries Ltd Chromone derivatives
IL89840A (en) * 1988-04-06 1996-10-31 Lipha Substituted flavonoid compounds and salts thereof their preparation and pharmaceutical composition containing them
USH1427H (en) * 1988-04-06 1995-04-04 Briet; Phillipe Substituted flavonoid compounds, their salts, their manufacture and their use in combination with interleukin-2
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
US5126129A (en) * 1988-05-23 1992-06-30 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Cancer therapy using interleukin-2 and flavone compounds
JPH04502761A (ja) * 1989-01-19 1992-05-21 ジ・アップジョン・カンパニー フッ素化フラボン酢酸
US5238954A (en) * 1989-01-19 1993-08-24 The Upjohn Company Fluorinated flavone acetic acid
US5716982A (en) * 1995-06-07 1998-02-10 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Retinoids and methods of use of same
US5703130A (en) * 1995-06-07 1997-12-30 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Chalcone retinoids and methods of use of same
US5968940A (en) * 1995-06-08 1999-10-19 Institute Of Materia Medica Retinoids and methods of use of same
AU5717400A (en) * 1999-06-14 2001-01-02 Cancer Research Ventures Limited Cancer therapy
AU2001232917A1 (en) 2000-01-24 2001-07-31 Jozef S. Mruk Use of flavone 8-acetic acid in vascular and cardiovascular interventions and acute coronary syndromes
WO2002009700A1 (en) * 2000-07-28 2002-02-07 Cancer Research Technology Limited Cancer treatment by combination therapy
GB0121285D0 (en) * 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
GB2386836B (en) * 2002-03-22 2006-07-26 Cancer Res Ventures Ltd Anti-cancer combinations
GB2394658A (en) * 2002-11-01 2004-05-05 Cancer Rec Tech Ltd Oral anti-cancer composition
GB0321999D0 (en) * 2003-09-19 2003-10-22 Cancer Rec Tech Ltd Anti-cancer combinations
AU2006283371A1 (en) * 2005-08-26 2007-03-01 Antisoma Research Limited Combinations comprising DMXAA for the treatment of cancer
EP2470174A1 (en) 2009-08-27 2012-07-04 Merck Patent GmbH Use of faa and its derivatives in cosmetics and dermatology
DK2496567T3 (en) 2009-11-05 2017-10-30 Rhizen Pharmaceuticals S A PRESENT UNKNOWN BENZOPYRANKINA MODULATORS
CN103304531A (zh) * 2013-06-25 2013-09-18 南方医科大学 一种3-芳基黄酮乙酸
KR20180120746A (ko) * 2016-03-11 2018-11-06 에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨 이카리인 및 이카리틴 유도체

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921070A (en) * 1957-11-05 1960-01-12 Recordati Lab Farmacologico S Basic esters of 3-methylflavone-8-carboxylic acid
US3350411A (en) * 1963-10-10 1967-10-31 Pharma Seceph S A Soc D Expl C Process for preparing 3-methylflavone-8-carboxylic acid
BE757821A (fr) * 1970-08-01 1971-04-01 Recordati Chem Pharm Procede de preparation de l'acide 3-propionyl-salicylique et dederives de cet acide
GB1479518A (en) * 1973-12-27 1977-07-13 Erba Carlo Spa 5,6-benzo-ypsilon-pyrone derivatives
US4148900A (en) * 1973-12-27 1979-04-10 Carlo Erba S.P.A. 5:6-Benzo-γ-pyrone derivatives and process for their preparation
FR2281112A1 (fr) * 1974-08-05 1976-03-05 Lipha Nouveau medicament choleretique et anti-inflammatoire
GB1469823A (en) * 1974-08-13 1977-04-06 Farma Lepori Flavone derivatives
DE2549745A1 (de) * 1974-11-20 1976-05-26 Lipha Durch einen chromonylrest substituierte propionsaeuren sowie deren derivate und verwendungen

Also Published As

Publication number Publication date
ES8308323A1 (es) 1983-08-16
DK164163B (da) 1992-05-18
AU9073082A (en) 1983-06-02
YU43726B (en) 1989-10-31
DE3277970D1 (en) 1988-02-18
IN158843B (xx) 1987-01-31
SU1250171A3 (ru) 1986-08-07
MA19650A1 (fr) 1983-07-01
OA07257A (fr) 1984-04-30
CS248035B2 (en) 1987-01-15
EP0080934A1 (fr) 1983-06-08
DK523082A (da) 1983-05-26
US4602034A (en) 1986-07-22
HU192112B (en) 1987-05-28
NO159169B (no) 1988-08-29
CA1213595A (fr) 1986-11-04
ZA828436B (en) 1983-09-28
IE54130B1 (en) 1989-06-21
JPH0214352B2 (xx) 1990-04-06
DK164163C (da) 1992-10-19
DD204919A5 (de) 1983-12-14
EP0080934B1 (fr) 1988-01-13
US4783533A (en) 1988-11-08
NZ202596A (en) 1986-02-21
YU264982A (en) 1984-12-31
ES517637A0 (es) 1983-08-16
ATE31927T1 (de) 1988-01-15
AU563190B2 (en) 1987-07-02
MX173498B (es) 1994-03-10
FR2516922B1 (xx) 1984-02-10
IE822752L (en) 1983-05-25
JPS5896082A (ja) 1983-06-07
IL67291A0 (en) 1983-03-31
NO823940L (no) 1983-05-26
NO159169C (no) 1988-12-07
FR2516922A1 (fr) 1983-05-27
YU163084A (en) 1985-03-20

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