SE7908994L - Tiazolidin- och pyrrolidinderivat - Google Patents
Tiazolidin- och pyrrolidinderivatInfo
- Publication number
- SE7908994L SE7908994L SE7908994A SE7908994A SE7908994L SE 7908994 L SE7908994 L SE 7908994L SE 7908994 A SE7908994 A SE 7908994A SE 7908994 A SE7908994 A SE 7908994A SE 7908994 L SE7908994 L SE 7908994L
- Authority
- SE
- Sweden
- Prior art keywords
- tiazolidine
- pyrrolidine derivatives
- acids
- methylene
- sulfur
- Prior art date
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13509378A JPS5562060A (en) | 1978-10-31 | 1978-10-31 | Sulfur-containing compound |
| JP15516678A JPS5581854A (en) | 1978-12-14 | 1978-12-14 | Sulfur-containing compound |
| JP1251979A JPS55104275A (en) | 1979-02-06 | 1979-02-06 | Sulfur-containing compound |
| JP1881279A JPS55111481A (en) | 1979-02-19 | 1979-02-19 | Ester type hypotensive agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7908994L true SE7908994L (sv) | 1980-05-01 |
| SE448541B SE448541B (sv) | 1987-03-02 |
Family
ID=27455824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7908994A SE448541B (sv) | 1978-10-31 | 1979-10-30 | Nya tiazolidin- och pyrrolidinderivat samt en farmaceutisk beredning derav |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US4483861A (sv) |
| CH (1) | CH642351A5 (sv) |
| DE (1) | DE2944037A1 (sv) |
| FR (1) | FR2440365A1 (sv) |
| GB (1) | GB2038800B (sv) |
| IT (1) | IT1124841B (sv) |
| SE (1) | SE448541B (sv) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| JPS5683483A (en) * | 1979-12-13 | 1981-07-08 | Santen Pharmaceut Co Ltd | Thiazolidine compound |
| US4692458A (en) * | 1980-03-05 | 1987-09-08 | University Of Miami | Anti-hypertensive agents |
| US4482725A (en) * | 1980-04-03 | 1984-11-13 | E. R. Squibb & Sons, Inc. | S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics |
| DE3152643A1 (de) * | 1980-12-29 | 1982-12-16 | Santen Pharmaceutical Co Ltd | Heterocyclic 5-membered ring compounds |
| JPS57112381A (en) * | 1980-12-29 | 1982-07-13 | Santen Pharmaceut Co Ltd | Five-membered heterocyclic compound |
| US4661515A (en) * | 1982-07-21 | 1987-04-28 | Usv Pharmaceutical Corporation | Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity |
| HU203872B (en) * | 1989-07-14 | 1991-10-28 | Richter Gedeon Vegyeszet | Process for producing amides of acrylic acid and their salts and pharmaceutical compositions containing them |
| CN102573466A (zh) * | 2009-04-22 | 2012-07-11 | 墨卡托医疗系统公司 | 局部血管递送胍乙啶在治疗高血压中的用途 |
| JP6069336B2 (ja) | 2011-10-19 | 2017-02-01 | マーケイター メドシステムズ, インコーポレイテッド | 腎の脱神経を包含する治療効果を増強するための組織および細胞の局所的調節 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
| AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| AU518147B2 (en) * | 1976-12-03 | 1981-09-17 | E.R. Squibb & Sons, Inc. | Derivatives of thiazolidine, thiazine and morpholine carboxylic acids |
| US4091024A (en) * | 1976-12-03 | 1978-05-23 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
| IT1105731B (it) * | 1977-06-29 | 1985-11-04 | Yoshitomi Pharmaceutical | Composti di tiazolidina |
| JPS5834474B2 (ja) * | 1977-06-29 | 1983-07-27 | ウェルファイド株式会社 | チアゾリジン誘導体の製造法 |
| JPS5455565A (en) * | 1977-10-06 | 1979-05-02 | Santen Pharmaceut Co Ltd | Novel thiazolidine derivative |
| IT7851510A0 (it) * | 1977-10-28 | 1978-10-16 | Sandoz Ag | Ammidi di amminoacidi ciclici loro preparazione e loro applicazione quali medicamenti |
| US4233309A (en) * | 1977-12-06 | 1980-11-11 | Teijin Limited | Novel 1-substituted-3-acylpyrrole derivatives, platelet aggregation inhibitors containing them, as active ingredients, and processes for production of said derivatives |
| FR2412537A1 (fr) * | 1977-12-22 | 1979-07-20 | Science Union & Cie | Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique |
| PH15381A (en) * | 1978-02-21 | 1982-12-17 | Squibb & Sons Inc | Halogen substituted mercaptoacylamino acids |
| US4430344A (en) * | 1978-04-08 | 1984-02-07 | Santen Pharmaceutical Co., Ltd. | Antihypertensive 4-thiazolidinecarboxylic acids |
| US4282235A (en) * | 1978-05-22 | 1981-08-04 | E. R. Squibb & Sons, Inc. | Derivatives of thiazolidinecarboxylic acids and related acids |
| JPS584711B2 (ja) * | 1978-08-02 | 1983-01-27 | 参天製薬株式会社 | ピロリジン誘導体 |
| CA1144930A (en) * | 1978-08-11 | 1983-04-19 | Miguel A. Ondetti | Mercaptoacyl derivatives of substituted prolines |
| NL7809120A (nl) * | 1978-09-07 | 1980-03-11 | Oce Andeno B V Grubbenvorsterw | Werkwijze voor de bereiding van proline-derivaten. |
| JPS5829950B2 (ja) * | 1978-10-05 | 1983-06-25 | ウェルファイド株式会社 | 環状イミノカルボン酸誘導体およびその塩類 |
| US4290952A (en) * | 1980-06-23 | 1981-09-22 | American Home Products Corporation | Aryl-1-mercaptoalkanoylproline and homoproline derivatives |
| JPS5756425A (en) * | 1980-09-20 | 1982-04-05 | Santen Pharmaceut Co Ltd | Hypotensor |
-
1979
- 1979-10-22 US US06/086,996 patent/US4483861A/en not_active Expired - Lifetime
- 1979-10-25 GB GB7936988A patent/GB2038800B/en not_active Expired
- 1979-10-30 IT IT26923/79A patent/IT1124841B/it active
- 1979-10-30 SE SE7908994A patent/SE448541B/sv not_active IP Right Cessation
- 1979-10-31 DE DE19792944037 patent/DE2944037A1/de active Granted
- 1979-10-31 CH CH977979A patent/CH642351A5/de not_active IP Right Cessation
- 1979-10-31 FR FR7926983A patent/FR2440365A1/fr active Granted
-
1982
- 1982-07-06 US US06/395,128 patent/US4496578A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US4483861A (en) | 1984-11-20 |
| GB2038800A (en) | 1980-07-30 |
| DE2944037A1 (de) | 1980-05-08 |
| IT1124841B (it) | 1986-05-14 |
| IT7926923A0 (it) | 1979-10-30 |
| US4496578A (en) | 1985-01-29 |
| CH642351A5 (de) | 1984-04-13 |
| FR2440365A1 (fr) | 1980-05-30 |
| SE448541B (sv) | 1987-03-02 |
| DE2944037C2 (sv) | 1988-04-14 |
| GB2038800B (en) | 1983-05-05 |
| FR2440365B1 (sv) | 1983-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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