JPS5562060A - Sulfur-containing compound - Google Patents

Sulfur-containing compound

Info

Publication number
JPS5562060A
JPS5562060A JP13509378A JP13509378A JPS5562060A JP S5562060 A JPS5562060 A JP S5562060A JP 13509378 A JP13509378 A JP 13509378A JP 13509378 A JP13509378 A JP 13509378A JP S5562060 A JPS5562060 A JP S5562060A
Authority
JP
Japan
Prior art keywords
formula
compound
methylene
halogen
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13509378A
Other languages
Japanese (ja)
Other versions
JPS6213350B2 (en
Inventor
Junichi Iwao
Masayuki Ooya
Tadashi Iso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Priority to JP13509378A priority Critical patent/JPS5562060A/en
Priority to US06/086,996 priority patent/US4483861A/en
Priority to GB7936988A priority patent/GB2038800B/en
Priority to IT26923/79A priority patent/IT1124841B/en
Priority to SE7908994A priority patent/SE448541B/en
Priority to FR7926983A priority patent/FR2440365A1/en
Priority to CH977979A priority patent/CH642351A5/en
Priority to DE19792944037 priority patent/DE2944037A1/en
Publication of JPS5562060A publication Critical patent/JPS5562060A/en
Priority to US06/395,128 priority patent/US4496578A/en
Publication of JPS6213350B2 publication Critical patent/JPS6213350B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Compounds of formula I [Q<1>, Q<2> are methylene, O, S, wherein at least one is methylene; R<1> is H, alkyl, cycloalkyl, aralkyl, which may be substituted with lowr alkyl, hydroxy, lower alkoxy, halogen, etc., R<2> is lower alkanoyl, substituted or unsubstituted benzoyl, pyridiylcarbonyl; Z is 1-3C alkylene] or their salts. EXAMPLE:(4R)-3-[ (2s)-S-Acetyl-3-mercapto-2-methylpropanoyl ]-4-thiazolidine- carboxylic acid. USE:Hypotensor; The reduction of potency is lowered because it is more stable than existing preparations. PREPARATION:For example, the Schotten-Baumann reaction between a compound of R<2>SZCOY (Y is OH, halogen) and another compound of formula II (R<3> equals to R<1>; however, in the group resulting from removing R<1> from formula I, COZSR<2> shows the group that is sustituted with H) is effected to give the compound of formula I.
JP13509378A 1978-10-31 1978-10-31 Sulfur-containing compound Granted JPS5562060A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP13509378A JPS5562060A (en) 1978-10-31 1978-10-31 Sulfur-containing compound
US06/086,996 US4483861A (en) 1978-10-31 1979-10-22 Antihypertensive sulfur-containing compounds
GB7936988A GB2038800B (en) 1978-10-31 1979-10-25 Antihypertensive sulphurcontaining compounds
IT26923/79A IT1124841B (en) 1978-10-31 1979-10-30 COMPOUNDS CONTAINING SULFUR ANTI-HYPERTENSION
SE7908994A SE448541B (en) 1978-10-31 1979-10-30 NEW TIAZOLIDINE AND PYRROLIDINE DERIVATIVES AND A PHARMACEUTICAL PREPARATION THEREOF
FR7926983A FR2440365A1 (en) 1978-10-31 1979-10-31 NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS
CH977979A CH642351A5 (en) 1978-10-31 1979-10-31 Antihypertensive, SULPHUR CONTAINING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND CONTAINING THEM Pharmaceutical Compositions.
DE19792944037 DE2944037A1 (en) 1978-10-31 1979-10-31 ANTI-HYPERTENSIVE SULFURING COMPOUNDS
US06/395,128 US4496578A (en) 1978-10-31 1982-07-06 Antihypertensive sulfur-containing compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13509378A JPS5562060A (en) 1978-10-31 1978-10-31 Sulfur-containing compound

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP60006850A Division JPS6122064A (en) 1985-01-18 1985-01-18 Sulfur-containing compound

Publications (2)

Publication Number Publication Date
JPS5562060A true JPS5562060A (en) 1980-05-10
JPS6213350B2 JPS6213350B2 (en) 1987-03-25

Family

ID=15143663

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13509378A Granted JPS5562060A (en) 1978-10-31 1978-10-31 Sulfur-containing compound

Country Status (1)

Country Link
JP (1) JPS5562060A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5382778A (en) * 1976-12-03 1978-07-21 Squibb & Sons Inc Thiazolidinecarboxylate derivative and related compounds thereof process for preparing same and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5382778A (en) * 1976-12-03 1978-07-21 Squibb & Sons Inc Thiazolidinecarboxylate derivative and related compounds thereof process for preparing same and application thereof

Also Published As

Publication number Publication date
JPS6213350B2 (en) 1987-03-25

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