JPS5562060A - Sulfur-containing compound - Google Patents
Sulfur-containing compoundInfo
- Publication number
- JPS5562060A JPS5562060A JP13509378A JP13509378A JPS5562060A JP S5562060 A JPS5562060 A JP S5562060A JP 13509378 A JP13509378 A JP 13509378A JP 13509378 A JP13509378 A JP 13509378A JP S5562060 A JPS5562060 A JP S5562060A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- methylene
- halogen
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula I [Q<1>, Q<2> are methylene, O, S, wherein at least one is methylene; R<1> is H, alkyl, cycloalkyl, aralkyl, which may be substituted with lowr alkyl, hydroxy, lower alkoxy, halogen, etc., R<2> is lower alkanoyl, substituted or unsubstituted benzoyl, pyridiylcarbonyl; Z is 1-3C alkylene] or their salts. EXAMPLE:(4R)-3-[ (2s)-S-Acetyl-3-mercapto-2-methylpropanoyl ]-4-thiazolidine- carboxylic acid. USE:Hypotensor; The reduction of potency is lowered because it is more stable than existing preparations. PREPARATION:For example, the Schotten-Baumann reaction between a compound of R<2>SZCOY (Y is OH, halogen) and another compound of formula II (R<3> equals to R<1>; however, in the group resulting from removing R<1> from formula I, COZSR<2> shows the group that is sustituted with H) is effected to give the compound of formula I.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13509378A JPS5562060A (en) | 1978-10-31 | 1978-10-31 | Sulfur-containing compound |
US06/086,996 US4483861A (en) | 1978-10-31 | 1979-10-22 | Antihypertensive sulfur-containing compounds |
GB7936988A GB2038800B (en) | 1978-10-31 | 1979-10-25 | Antihypertensive sulphurcontaining compounds |
IT26923/79A IT1124841B (en) | 1978-10-31 | 1979-10-30 | COMPOUNDS CONTAINING SULFUR ANTI-HYPERTENSION |
SE7908994A SE448541B (en) | 1978-10-31 | 1979-10-30 | NEW TIAZOLIDINE AND PYRROLIDINE DERIVATIVES AND A PHARMACEUTICAL PREPARATION THEREOF |
FR7926983A FR2440365A1 (en) | 1978-10-31 | 1979-10-31 | NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS |
CH977979A CH642351A5 (en) | 1978-10-31 | 1979-10-31 | Antihypertensive, SULPHUR CONTAINING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND CONTAINING THEM Pharmaceutical Compositions. |
DE19792944037 DE2944037A1 (en) | 1978-10-31 | 1979-10-31 | ANTI-HYPERTENSIVE SULFURING COMPOUNDS |
US06/395,128 US4496578A (en) | 1978-10-31 | 1982-07-06 | Antihypertensive sulfur-containing compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13509378A JPS5562060A (en) | 1978-10-31 | 1978-10-31 | Sulfur-containing compound |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60006850A Division JPS6122064A (en) | 1985-01-18 | 1985-01-18 | Sulfur-containing compound |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5562060A true JPS5562060A (en) | 1980-05-10 |
JPS6213350B2 JPS6213350B2 (en) | 1987-03-25 |
Family
ID=15143663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13509378A Granted JPS5562060A (en) | 1978-10-31 | 1978-10-31 | Sulfur-containing compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5562060A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5382778A (en) * | 1976-12-03 | 1978-07-21 | Squibb & Sons Inc | Thiazolidinecarboxylate derivative and related compounds thereof process for preparing same and application thereof |
-
1978
- 1978-10-31 JP JP13509378A patent/JPS5562060A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5382778A (en) * | 1976-12-03 | 1978-07-21 | Squibb & Sons Inc | Thiazolidinecarboxylate derivative and related compounds thereof process for preparing same and application thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS6213350B2 (en) | 1987-03-25 |
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