JPS55104275A - Sulfur-containing compound - Google Patents

Sulfur-containing compound

Info

Publication number
JPS55104275A
JPS55104275A JP1251979A JP1251979A JPS55104275A JP S55104275 A JPS55104275 A JP S55104275A JP 1251979 A JP1251979 A JP 1251979A JP 1251979 A JP1251979 A JP 1251979A JP S55104275 A JPS55104275 A JP S55104275A
Authority
JP
Japan
Prior art keywords
compound
formula
sulfur
containing compound
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1251979A
Other languages
Japanese (ja)
Other versions
JPS6213955B2 (en
Inventor
Junichi Iwao
Masayuki Ooya
Tadashi Iso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Priority to JP1251979A priority Critical patent/JPS55104275A/en
Priority to US06/086,996 priority patent/US4483861A/en
Priority to GB7936988A priority patent/GB2038800B/en
Priority to SE7908994A priority patent/SE448541B/en
Priority to IT26923/79A priority patent/IT1124841B/en
Priority to DE19792944037 priority patent/DE2944037A1/en
Priority to FR7926983A priority patent/FR2440365A1/en
Priority to CH977979A priority patent/CH642351A5/en
Publication of JPS55104275A publication Critical patent/JPS55104275A/en
Priority to US06/395,128 priority patent/US4496578A/en
Publication of JPS6213955B2 publication Critical patent/JPS6213955B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A sulfur-containing compound of formula I (R1 is H, lower alkyl, higher alkyl, cycloalkyl, aralkyl, phenyl, etc.; R2 is lower alkyl, higher alkanoyl, 6W7C cycloalkanecarbonyl, naphthoyl, etc.; Z is 1W3C straight or branched chain alkylene), and its salt.
EXAMPLE: (4R)-3-[ (2s)-S-Methyl-3-mercapto-2-methylpropanoyl ]-4-thiazolidinecarboxylic acid.
USE: A long-acting hypotensor. Free from lowering of titer and emission of ill-odor during or after the preparation.
PROCESS: The compound of formula I can be prepared, e.g. from the compound of formula II (Y is OH or halogen) and a compound III (R3 is same as R1) by a conventional process such as Schotten-Baumann reaction, mixed acid anhydride reaction, etc.
COPYRIGHT: (C)1980,JPO&Japio
JP1251979A 1978-10-31 1979-02-06 Sulfur-containing compound Granted JPS55104275A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP1251979A JPS55104275A (en) 1979-02-06 1979-02-06 Sulfur-containing compound
US06/086,996 US4483861A (en) 1978-10-31 1979-10-22 Antihypertensive sulfur-containing compounds
GB7936988A GB2038800B (en) 1978-10-31 1979-10-25 Antihypertensive sulphurcontaining compounds
SE7908994A SE448541B (en) 1978-10-31 1979-10-30 NEW TIAZOLIDINE AND PYRROLIDINE DERIVATIVES AND A PHARMACEUTICAL PREPARATION THEREOF
IT26923/79A IT1124841B (en) 1978-10-31 1979-10-30 COMPOUNDS CONTAINING SULFUR ANTI-HYPERTENSION
DE19792944037 DE2944037A1 (en) 1978-10-31 1979-10-31 ANTI-HYPERTENSIVE SULFURING COMPOUNDS
FR7926983A FR2440365A1 (en) 1978-10-31 1979-10-31 NOVEL MERCAPTO-AZOLIDINE-CARBOXYLIC ACID DERIVATIVES USEFUL AS HYPERTENSORS
CH977979A CH642351A5 (en) 1978-10-31 1979-10-31 Antihypertensive, SULPHUR CONTAINING COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND CONTAINING THEM Pharmaceutical Compositions.
US06/395,128 US4496578A (en) 1978-10-31 1982-07-06 Antihypertensive sulfur-containing compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1251979A JPS55104275A (en) 1979-02-06 1979-02-06 Sulfur-containing compound

Publications (2)

Publication Number Publication Date
JPS55104275A true JPS55104275A (en) 1980-08-09
JPS6213955B2 JPS6213955B2 (en) 1987-03-30

Family

ID=11807584

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1251979A Granted JPS55104275A (en) 1978-10-31 1979-02-06 Sulfur-containing compound

Country Status (1)

Country Link
JP (1) JPS55104275A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982002200A1 (en) * 1980-12-29 1982-07-08 Iwao Jun Ichi Heterocyclic 5-membered ring compounds
JPS58172382A (en) * 1982-03-22 1983-10-11 モンテデイソン・エツセ・ピ・ア Plant growth regulant or biostimulant 3-acyl substituted derivatives of 2- or 4-thiazolidine carboxylic acid

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982002200A1 (en) * 1980-12-29 1982-07-08 Iwao Jun Ichi Heterocyclic 5-membered ring compounds
US4464371A (en) * 1980-12-29 1984-08-07 Santen Pharmaceutical Co., Ltd. Five-membered heterocyclic compounds
JPS58172382A (en) * 1982-03-22 1983-10-11 モンテデイソン・エツセ・ピ・ア Plant growth regulant or biostimulant 3-acyl substituted derivatives of 2- or 4-thiazolidine carboxylic acid

Also Published As

Publication number Publication date
JPS6213955B2 (en) 1987-03-30

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