JPS57144254A - 2-substituted-2-oxoazetidine derivative and its preparation - Google Patents
2-substituted-2-oxoazetidine derivative and its preparationInfo
- Publication number
- JPS57144254A JPS57144254A JP56029387A JP2938781A JPS57144254A JP S57144254 A JPS57144254 A JP S57144254A JP 56029387 A JP56029387 A JP 56029387A JP 2938781 A JP2938781 A JP 2938781A JP S57144254 A JPS57144254 A JP S57144254A
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- oxoazetidine
- derivative
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The N-substituted-2-oxoazetidine derivative of formulaI(R1 is H, alkoxy, aryloxy, alkylthio, arylthio, halogen, acyloxy, azido or amino; Ar is aromatic group; R2 is H, alkyl, aryl, alkylsilyl or a salt-forming metal cation).
EXAMPLE: β-(4-Methylthio-2-oxoazetidine-1-yl)-cinnamic acid methyl ester.
USE: Antibiotic agent and β-lactamase-inhibiting agent.
PROCESS: The compound of formulaIcan be prepared by reacting the 2-oxoazetidine derivative of formula II with the substituted sulfinylacrylic acid derivative of formula III (R3 is alkyl or aryl) in the presence of a base such as alkali metal hydride.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56029387A JPS57144254A (en) | 1981-03-03 | 1981-03-03 | 2-substituted-2-oxoazetidine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56029387A JPS57144254A (en) | 1981-03-03 | 1981-03-03 | 2-substituted-2-oxoazetidine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57144254A true JPS57144254A (en) | 1982-09-06 |
Family
ID=12274721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56029387A Pending JPS57144254A (en) | 1981-03-03 | 1981-03-03 | 2-substituted-2-oxoazetidine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57144254A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5944355A (en) * | 1982-09-03 | 1984-03-12 | Takeda Chem Ind Ltd | 2-azetidinone derivative and its preparation |
JPH075513B2 (en) * | 1990-06-14 | 1995-01-25 | ファイザー・インコーポレーテッド | 3-Aryl-2-hydroxypropionic acid derivatives and homologues as hypoglycemic agents |
-
1981
- 1981-03-03 JP JP56029387A patent/JPS57144254A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5944355A (en) * | 1982-09-03 | 1984-03-12 | Takeda Chem Ind Ltd | 2-azetidinone derivative and its preparation |
JPH0321026B2 (en) * | 1982-09-03 | 1991-03-20 | Takeda Chemical Industries Ltd | |
JPH075513B2 (en) * | 1990-06-14 | 1995-01-25 | ファイザー・インコーポレーテッド | 3-Aryl-2-hydroxypropionic acid derivatives and homologues as hypoglycemic agents |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MY101891A (en) | Novel carbostyril derivative and process for preparing same. | |
JPS5576829A (en) | Beta,gamma-dihydropolyprenyl alcohol and hypotensive agent made from it | |
JPS57108066A (en) | 4-substituted-2-oxoazetidine derivative and its preparation | |
JPS57118555A (en) | Leucotriene-analog compound, its preparation, and leucotriene-biosynthesis inhibiting agent containing said compound as active component | |
JPS57144254A (en) | 2-substituted-2-oxoazetidine derivative and its preparation | |
JPS55111463A (en) | Beta-lactam compound and its preparation | |
JPS57144269A (en) | Triazine derivative and its preparation | |
JPS5772981A (en) | 1,8-naphthyridine derivative and its salt | |
JPS54151985A (en) | Preparation of aminocarbostyril derivative | |
JPS57192342A (en) | Isoprenylamine derivative | |
JPS5566592A (en) | 7-alkoxythiazolo 3,2-a pyrimidine derivative, its preparation, and drug containing the same | |
JPS57102838A (en) | 9-halogeno-8-hydroxy-4-methyl-4-nonenoic acid, its derivative and their preparation | |
JPS55104275A (en) | Sulfur-containing compound | |
JPS579784A (en) | Production of penem-3-carboxylic derivative | |
JPS5770860A (en) | Carboxylic acid derivative and its salt | |
JPS5759897A (en) | Thiazolineazatidinone | |
JPS54128599A (en) | Pyrrolobenzazepin derivative | |
JPS55115887A (en) | 7beta-(4-lower alkylimino-1,3-dithietane-2-yl)carboxamide-3- (1-lower alkyltetrazol-5-yl)thiomethyl-delta3-cephem-4- carboxylic acid | |
JPS5625166A (en) | 5-fluorouracil derivative | |
JPS57169489A (en) | Cephalosporin derivative and its preparation | |
JPS5756484A (en) | Production of 3-acylamino-2-oxoazetidine-1-acetic acid derivative | |
JPS57106699A (en) | Novel steroid and its preparation | |
JPS57206687A (en) | Cephalosporin derivative and its preparation | |
JPS57158787A (en) | 1-h-4-h-pyrazolo(4',3':5,6)pyrano(2,3-b)pyridine derivative | |
JPS57156447A (en) | Ether compound and its synthesis |